NL139234B - Werkwijze ter bereiding van een geneesmiddel, dat de werking van adrenaline blokkeert, alsmede werkwijze ter bereiding van de daarin te gebruiken actieve verbindingen. - Google Patents
Werkwijze ter bereiding van een geneesmiddel, dat de werking van adrenaline blokkeert, alsmede werkwijze ter bereiding van de daarin te gebruiken actieve verbindingen.Info
- Publication number
- NL139234B NL139234B NL646408650A NL6408650A NL139234B NL 139234 B NL139234 B NL 139234B NL 646408650 A NL646408650 A NL 646408650A NL 6408650 A NL6408650 A NL 6408650A NL 139234 B NL139234 B NL 139234B
- Authority
- NL
- Netherlands
- Prior art keywords
- preparing
- adrenaline
- blocks
- action
- active compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
- C07D311/82—Xanthenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D321/00—Heterocyclic compounds containing rings having two oxygen atoms as the only ring hetero atoms, not provided for by groups C07D317/00 - C07D319/00
- C07D321/02—Seven-membered rings
- C07D321/10—Seven-membered rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D321/00—Heterocyclic compounds containing rings having two oxygen atoms as the only ring hetero atoms, not provided for by groups C07D317/00 - C07D319/00
- C07D321/12—Eight-membered rings
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB30135/63A GB1058822A (en) | 1963-07-30 | 1963-07-30 | 3-amino-2-hydroxypropoxy heterocyclic derivatives |
GB199064 | 1964-01-16 |
Publications (2)
Publication Number | Publication Date |
---|---|
NL6408650A NL6408650A (nl) | 1965-02-01 |
NL139234B true NL139234B (nl) | 1973-07-16 |
Family
ID=26237125
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL646408650A NL139234B (nl) | 1963-07-30 | 1964-07-29 | Werkwijze ter bereiding van een geneesmiddel, dat de werking van adrenaline blokkeert, alsmede werkwijze ter bereiding van de daarin te gebruiken actieve verbindingen. |
Country Status (10)
Country | Link |
---|---|
US (1) | US3340266A (nl) |
BE (1) | BE651032A (nl) |
BR (1) | BR6461288D0 (nl) |
CH (2) | CH468372A (nl) |
DK (2) | DK119432B (nl) |
ES (1) | ES302622A1 (nl) |
FR (2) | FR1583153A (nl) |
GB (1) | GB1058822A (nl) |
NL (1) | NL139234B (nl) |
SE (4) | SE316781C (nl) |
Families Citing this family (49)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3509170A (en) * | 1967-06-12 | 1970-04-28 | Du Pont | Heterocyclic amino-oxazolines |
GB1253709A (en) * | 1968-05-22 | 1971-11-17 | Frosst & Co Charles E | Thiadiazole derivatives |
US3655661A (en) * | 1968-05-22 | 1972-04-11 | Frosst & Co Charles E | Benzothiadiazole compounds |
US3668206A (en) * | 1968-10-16 | 1972-06-06 | Venkatachala Lakshmi Narayanan | Heterocyclic amine derivatives of 5,8-dihydronaphthyloxy propanols |
GB1308191A (en) * | 1970-04-06 | 1973-02-21 | Science Union & Cie | Thiochroman derivatives and a process for preparing them |
US3853923A (en) * | 1971-05-13 | 1974-12-10 | Kakenyaku Kako Kk | 2-substituted-(2-hydroxy-3-lower alkaminopropoxy)-benzofurans |
JPS517672B2 (nl) * | 1972-04-13 | 1976-03-10 | ||
US3910924A (en) * | 1972-04-13 | 1975-10-07 | Otsuka Pharma Co Ltd | 3,4-Dihydrocarbostyril derivatives and a process for preparing the same |
US3856818A (en) * | 1972-07-03 | 1974-12-24 | Squibb & Sons Inc | Tricyclic phenoxy aminopropanols |
AR207554A1 (es) * | 1972-12-02 | 1976-10-15 | Otsuka Pharma Co Ltd | Procedimiento para producir derivados de 3-alquil-5-((3,4-dihidro-5-carbostiril)oximetil)-oxazolidinona-(2) |
JPS5239035B2 (nl) * | 1972-12-14 | 1977-10-03 | ||
US4073909A (en) * | 1973-10-08 | 1978-02-14 | Sandoz Ltd. | Isoquinoline compounds |
GB1509527A (en) * | 1974-06-05 | 1978-05-04 | Ici Ltd | 1-(aryl-or heteroaryl)oxy-3-(substituted-amino)propan-2-ol derivatives processes for their manufacture and pharmaceutical compositions containing them |
US3894058A (en) * | 1974-05-17 | 1975-07-08 | Hoechst Co American | Tetrahydrobenzofuranylphenoxypropylamines |
US4070470A (en) * | 1974-06-24 | 1978-01-24 | Otsuka Pharmaceutical Co., Ltd. | Platelet aggregation inhibiting carbostyrils, their compositions and method of use |
GB1472959A (en) * | 1974-09-26 | 1977-05-11 | Roche Products Ltd | Benzofuran derivatives and a process for the manufacture thereof |
FI58329C (fi) * | 1974-11-08 | 1981-01-12 | Otsuka Pharma Co Ltd | Foerfarande foer framstaellning av i 8-staellning substituerade 5-(3'-alkylamino-2'-hydroxi)propoxi-3,4-dihydrokarbostyrilderivat |
AR206061A1 (es) * | 1974-11-15 | 1976-06-23 | Knoll Ag | Procedimiento para la produccion de nuevas 2-alcanoil (c1-c4)-1, 2, 3, 4-tetrahidro-8-respectivamente 7-, 6- o 5-(2-hidroxi-3-alquil (c3-c4)-aminopropoxi)-isoquinolinas de 2-alcanoil (c1-c4)-1, 2, 3, 4-tetrahidro-8-respectivamente 7- o 5-(2-hidroxi-3-alquil (c3-c4)-aminopropoxi)-6-metoxi-isoquinolinas y de 2-alcanoil (c1-c4)-1, 2, 3, 4-tetrahidro-8-respectivamente 6- o 5-(2-hidroxi-3-alquil (c3-c4)-aminopropoxi)-7-metoxi-isoquinolinas eventualmente metiladas en la posicion 1 |
GB1544952A (en) * | 1975-03-26 | 1979-04-25 | Sandoz Ltd | Isoquinolines |
FI760704A (nl) * | 1975-03-26 | 1976-09-27 | Sandoz Ag | |
US4081447A (en) * | 1975-04-09 | 1978-03-28 | Abbott Laboratories | 5-[2-Hydroxy-3-(3,4-dimethoxy phenethylamino)]-propoxy-3,4-dihydro carbostyril and pharmaceutically acceptable salts thereof |
GB1504424A (en) * | 1975-08-09 | 1978-03-22 | Beecham Group Ltd | Isoquinoline-derived aminoethers |
CA1089866A (en) * | 1975-10-20 | 1980-11-18 | Kiyoshi Ito | Benzofuran derivatives, preparation thereof and pharmaceutical compositions thereof |
US4139537A (en) | 1976-06-29 | 1979-02-13 | Cooper Laboratories, Inc. | 3-Aryloxy-1-(2- or 4-iminodihydro-1-pyridyl)-2-propanol antiarrhythmic compounds |
DE2704793C2 (de) * | 1977-02-05 | 1979-03-08 | Basf Ag, 6700 Ludwigshafen | 4-Hydroxy-l,2-benzisothiazole |
DE2704794C3 (de) * | 1977-02-05 | 1979-10-11 | Basf Ag, 6700 Ludwigshafen | Aminopropanolderivate des 4-Hydroxy-l^-benzisothiazols |
NZ187066A (en) * | 1977-05-03 | 1981-02-11 | Hoffmann La Roche | 4-(3-substitutedamino-2-hydroxypropoxy)-benzimidazolidin-2-(ones or thiones) |
US4235919A (en) * | 1977-07-21 | 1980-11-25 | Sandoz Ltd. | 1-(Indol-4-yloxy)-3-(2-substituted amino)-2-propanols and pharmaceutical use thereof |
DE2801980A1 (de) * | 1978-01-18 | 1979-07-19 | Boehringer Mannheim Gmbh | 4-hydroxy-2-benzimidazolin-thion- derivate, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel |
US4202978A (en) * | 1978-02-08 | 1980-05-13 | Hoffmann-La Roche Inc. | (S)-1-[2-(4-(2-Hydroxy-s-(1-alkylaminopropoxy)phenylalkyl]-4-phenylpiperazines |
EP0003758A1 (de) * | 1978-02-09 | 1979-09-05 | Ciba-Geigy Ag | Verätherte Hydroxy-benzodiheterocyclen und ihre Säureadditionssalze, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Präparate |
DE2901336A1 (de) | 1979-01-15 | 1980-07-24 | Boehringer Mannheim Gmbh | Neue arylether, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel |
IE810250L (en) * | 1980-02-11 | 1981-08-11 | Berlex Lab | N-(3-phenoxy-2-hydroxypropyl) benzimidazole -1-¹alkanamines. |
FR2479825A1 (fr) * | 1980-04-04 | 1981-10-09 | Fabre Sa Pierre | Benzodioxanne 1,4 methoxy-2 propanolamines, leur preparation et leur application en tant que medicaments |
US4472427A (en) * | 1980-12-23 | 1984-09-18 | Merck & Co., Inc. | (Aralkylamino-2-OR-propoxy)heterocyclic compounds |
CA1188311A (en) * | 1981-05-01 | 1985-06-04 | Edwin S. Wu | Antihypertensive agents |
US4473501A (en) * | 1981-05-04 | 1984-09-25 | G. D. Searle & Co. | Dihydro azino isoquinolines |
US4471128A (en) * | 1981-09-08 | 1984-09-11 | Ciba-Geigy Corporation | 1,5-Bis-(1,4-benzodioxin-2-yl)-3-azapentane-1,5-diols |
JPS5846079A (ja) * | 1981-09-12 | 1983-03-17 | Santen Pharmaceut Co Ltd | ベンゾチアゾリン環を有するエ−テル類 |
FR2588260B1 (fr) * | 1985-10-04 | 1987-11-20 | Adir | Nouveau derive du thiochromanne, son procede de preparation et les compositions pharmaceutiques qui le contiennent |
DK630987D0 (da) * | 1987-12-01 | 1987-12-01 | Ferrosan As | Aryloxyphenylpropylaminer, deres fremstilling og anvendelse |
US5198448A (en) * | 1988-08-10 | 1993-03-30 | Otsuka Pharmaceutical Company, Limited | Cardiotonics |
US5053514A (en) * | 1988-08-10 | 1991-10-01 | Otsuka Pharmaceutical Company, Limited | Cardiotonics |
US5266577A (en) * | 1988-08-10 | 1993-11-30 | Otsuka Pharmaceutical Company Ltd. | Method of treating congestive heart failure using carbostyril derivatives |
FR2746395B1 (fr) * | 1996-03-22 | 1998-04-17 | Adir | Nouveaux derives d'arylethanolamine et d'aryloxypropanolamine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
US6818660B2 (en) | 1996-04-09 | 2004-11-16 | Nps Pharmaceuticals, Inc. | Calcilytic compounds |
EA002984B1 (ru) * | 1996-04-09 | 2002-12-26 | Эн Пи Эс Фармасьютикалз, Инк. | Кальцилитические соединения, фармацевтические композиции и способ скрининга кальцилитических соединений |
US7202261B2 (en) | 1996-12-03 | 2007-04-10 | Nps Pharmaceuticals, Inc. | Calcilytic compounds |
TW483881B (en) | 1996-12-03 | 2002-04-21 | Nps Pharma Inc | Calcilytic compounds |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2807567A (en) * | 1953-06-02 | 1957-09-24 | Saul & Co | Preparation for the treatment of allergic diseases |
US2872374A (en) * | 1955-02-02 | 1959-02-03 | Nat Drug Co | Muscle-relaxing tranquilizer compositions |
US2984668A (en) * | 1958-07-31 | 1961-05-16 | Searle & Co | 3-(2-hydroxyethyl)-4-methyl-5-phenyloxazolidine and certain esters |
US3198806A (en) * | 1963-08-07 | 1965-08-03 | Dow Chemical Co | 2-alkoxy-2-oxazolines |
-
1963
- 1963-07-30 GB GB30135/63A patent/GB1058822A/en not_active Expired
-
1964
- 1964-07-20 CH CH949464A patent/CH468372A/de unknown
- 1964-07-20 CH CH1481668A patent/CH472402A/de not_active IP Right Cessation
- 1964-07-20 US US383940A patent/US3340266A/en not_active Expired - Lifetime
- 1964-07-27 BE BE651032A patent/BE651032A/xx unknown
- 1964-07-29 SE SE922764A patent/SE316781C/xx unknown
- 1964-07-29 NL NL646408650A patent/NL139234B/nl unknown
- 1964-07-29 SE SE7992/66A patent/SE316488B/xx unknown
- 1964-07-30 DK DK377564AA patent/DK119432B/da unknown
- 1964-07-30 FR FR1583153D patent/FR1583153A/fr not_active Expired - Lifetime
- 1964-07-30 BR BR161288/64A patent/BR6461288D0/pt unknown
- 1964-07-30 ES ES0302622A patent/ES302622A1/es not_active Expired
- 1964-10-29 FR FR993196A patent/FR4161M/fr not_active Expired
-
1965
- 1965-12-03 DK DK623065AA patent/DK111267B/da unknown
-
1966
- 1966-06-10 SE SE799166A patent/SE316487C/xx unknown
- 1966-06-10 SE SE799066A patent/SE316486C/xx unknown
Also Published As
Publication number | Publication date |
---|---|
DK111267B (da) | 1968-07-15 |
DE1493853A1 (de) | 1969-06-04 |
NL6408650A (nl) | 1965-02-01 |
US3340266A (en) | 1967-09-05 |
CH472402A (de) | 1969-05-15 |
CH468372A (de) | 1969-02-15 |
SE316781B (sv) | 1969-11-03 |
SE316487C (sv) | 1972-11-02 |
ES302622A1 (es) | 1965-03-16 |
BR6461288D0 (pt) | 1973-08-09 |
SE316486C (sv) | 1972-11-02 |
SE316486B (sv) | 1969-10-27 |
FR1583153A (nl) | 1969-10-24 |
DK119432B (da) | 1971-01-04 |
GB1058822A (en) | 1967-02-15 |
BE651032A (nl) | 1965-01-27 |
SE316488B (nl) | 1969-10-27 |
FR4161M (nl) | 1966-05-16 |
SE316487B (sv) | 1969-10-27 |
SE316781C (sv) | 1972-11-02 |
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