CA2903583C - Microarray for delivery of therapeutic agent, methods of use, and methods of making - Google Patents

Microarray for delivery of therapeutic agent, methods of use, and methods of making Download PDF

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Publication number
CA2903583C
CA2903583C CA2903583A CA2903583A CA2903583C CA 2903583 C CA2903583 C CA 2903583C CA 2903583 A CA2903583 A CA 2903583A CA 2903583 A CA2903583 A CA 2903583A CA 2903583 C CA2903583 C CA 2903583C
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CA
Canada
Prior art keywords
suspension
drying
mold
solution
polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2903583A
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English (en)
French (fr)
Other versions
CA2903583A1 (en
Inventor
Guohua Chen
Zhongli Ding
Esi Ghartey-Tagoe
Ashutosh Shastry
Robert Wade Worsham
Parminder Singh
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Corium Innovations Inc
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Corium LLC
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Publication date
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Publication of CA2903583A1 publication Critical patent/CA2903583A1/en
Application granted granted Critical
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays or needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053—Methods for producing microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA2903583A 2013-03-15 2014-03-14 Microarray for delivery of therapeutic agent, methods of use, and methods of making Active CA2903583C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361792069P 2013-03-15 2013-03-15
US61/792,069 2013-03-15
PCT/US2014/029601 WO2014144973A1 (en) 2013-03-15 2014-03-14 Microarray for delivery of therapeutic agent, methods of use, and methods of making

Publications (2)

Publication Number Publication Date
CA2903583A1 CA2903583A1 (en) 2014-09-18
CA2903583C true CA2903583C (en) 2021-12-28

Family

ID=50629002

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2903583A Active CA2903583C (en) 2013-03-15 2014-03-14 Microarray for delivery of therapeutic agent, methods of use, and methods of making

Country Status (7)

Country Link
US (1) US9962534B2 (enExample)
EP (1) EP2968119B1 (enExample)
JP (3) JP2016512754A (enExample)
AU (1) AU2014233541B2 (enExample)
CA (1) CA2903583C (enExample)
ES (1) ES2761580T3 (enExample)
WO (1) WO2014144973A1 (enExample)

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EP2146689B1 (en) 2007-04-16 2020-08-12 Corium, Inc. Solvent-cast microneedle arrays containing active
US8911749B2 (en) 2007-04-16 2014-12-16 Corium International, Inc. Vaccine delivery via microneedle arrays
WO2009142741A1 (en) 2008-05-21 2009-11-26 Theraject, Inc. Method of manufacturing solid solution peforator patches and uses thereof
EP2429627B1 (en) * 2009-04-24 2017-06-14 Corium International, Inc. Methods for manufacturing microprojection arrays
JP6327852B2 (ja) 2010-05-04 2018-05-23 コリウム インターナショナル， インコーポレイテッド 微小突起アレイを使用した副甲状腺ホルモンの経皮送達のための方法及びデバイス
AU2013364053B2 (en) 2012-12-21 2018-08-30 Corium Pharma Solutions, Inc. Microarray for delivery of therapeutic agent and methods of use
CA2903748C (en) 2013-03-12 2021-11-02 Corium International, Inc. Microprojection applicators
BR112015022625B1 (pt) 2013-03-15 2023-01-31 Corium, Inc Aparelho de microestrutura para entrega de agente terapêutico
WO2014150285A2 (en) 2013-03-15 2014-09-25 Corium International, Inc. Multiple impact microprojection applicators and methods of use
US9962534B2 (en) 2013-03-15 2018-05-08 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
AU2014237279B2 (en) 2013-03-15 2018-11-22 Corium Pharma Solutions, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
JP6207459B2 (ja) * 2014-05-15 2017-10-04 富士フイルム株式会社 経皮吸収シートの製造方法
JP7109188B2 (ja) * 2014-08-29 2022-07-29 コリウム， インコーポレイテッド 活性剤の送達のための微細構造アレイ
WO2016036866A1 (en) 2014-09-04 2016-03-10 Corium International, Inc. Microstructure array, methods of making, and methods of use
JP6482323B2 (ja) 2015-03-03 2019-03-13 富士フイルム株式会社 経皮吸収シート
JP6317690B2 (ja) * 2015-03-03 2018-04-25 富士フイルム株式会社 経皮吸収シート、及びその製造方法
KR101676861B1 (ko) * 2015-04-10 2016-11-17 씨앤텍 주식회사 마이크로 니들 패치 제조장치와 방법, 및 이에 의해 제조되는 마이크로 니들 패치
US10857093B2 (en) 2015-06-29 2020-12-08 Corium, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
CN105833424A (zh) * 2016-03-21 2016-08-10 南通纺织丝绸产业技术研究院 一种丝素蛋白微针贴及其制备方法
WO2017208962A1 (ja) * 2016-05-31 2017-12-07 Ｎｉｓｓｈａ株式会社 マイクロニードルアレイ及びその製造方法
JP6691025B2 (ja) * 2016-09-06 2020-04-28 富士フイルム株式会社 針状アレイシートの製造方法
KR102401856B1 (ko) * 2017-02-17 2022-05-26 알레간 인코포레이티드 활성 성분을 갖는 마이크로니들 어레이
JP7260250B2 (ja) * 2017-03-03 2023-04-18 Ｎｉｓｓｈａ株式会社 かゆみ止めパッチ
KR102703839B1 (ko) * 2018-04-24 2024-09-05 주식회사 엠씨넷 피부투과성이 우수한 다층 마이크로니들 패치의 제조 방법
KR102526228B1 (ko) 2018-05-23 2023-04-26 후지필름 가부시키가이샤 일본 뇌염 백신 함유 마이크로니들 어레이
US20210276228A1 (en) 2018-06-25 2021-09-09 Corium, Inc. Hybrid method of forming microstructure array molds, methods of making microstructure arrays, and methods of use
CN116764087A (zh) * 2018-08-15 2023-09-19 阿勒根公司 具有活性成分的微针阵列
CN109674738A (zh) * 2019-01-21 2019-04-26 武汉长联来福制药股份有限公司 炎琥宁制剂、贴片及其制备方法

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