CA2878843A1 - Bispecific asymmetric heterodimers comprising anti-cd3 constructs - Google Patents
Bispecific asymmetric heterodimers comprising anti-cd3 constructs Download PDFInfo
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- CA2878843A1 CA2878843A1 CA2878843A CA2878843A CA2878843A1 CA 2878843 A1 CA2878843 A1 CA 2878843A1 CA 2878843 A CA2878843 A CA 2878843A CA 2878843 A CA2878843 A CA 2878843A CA 2878843 A1 CA2878843 A1 CA 2878843A1
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- cell
- polypeptide
- heteromultimer
- construct
- multispecific heteromultimer
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Classifications
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
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- C—CHEMISTRY; METALLURGY
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
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- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
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- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
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- Rheumatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
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| US201261671640P | 2012-07-13 | 2012-07-13 | |
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| US201361845948P | 2013-07-12 | 2013-07-12 | |
| US61/845,948 | 2013-07-12 | ||
| PCT/US2013/050411 WO2014012085A2 (en) | 2012-07-13 | 2013-07-13 | Bispecific asymmetric heterodimers comprising anti-cd3 constructs |
Publications (1)
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| CA2878843A1 true CA2878843A1 (en) | 2014-01-16 |
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| CA2878843A Abandoned CA2878843A1 (en) | 2012-07-13 | 2013-07-13 | Bispecific asymmetric heterodimers comprising anti-cd3 constructs |
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| WO (1) | WO2014012085A2 (cg-RX-API-DMAC7.html) |
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| WO2011028952A1 (en) | 2009-09-02 | 2011-03-10 | Xencor, Inc. | Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens |
| JP6091894B2 (ja) | 2009-09-16 | 2017-03-15 | ジェネンテック， インコーポレイテッド | コイルドコイルおよび／またはテザー含有タンパク質複合体およびその使用 |
| AR080793A1 (es) | 2010-03-26 | 2012-05-09 | Roche Glycart Ag | Anticuerpos biespecificos |
| WO2012016227A2 (en) | 2010-07-29 | 2012-02-02 | Xencor, Inc. | Antibodies with modified isoelectric points |
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| US20240343802A1 (en) | 2024-10-17 |
| HK1207575A1 (en) | 2016-02-05 |
| RU2650868C2 (ru) | 2018-04-17 |
| AU2013289883B2 (en) | 2018-11-01 |
| WO2014012085A2 (en) | 2014-01-16 |
| KR20150036606A (ko) | 2015-04-07 |
| EP2872170A2 (en) | 2015-05-20 |
| US20190248897A1 (en) | 2019-08-15 |
| EP2872170A4 (en) | 2016-06-22 |
| CN104640562A (zh) | 2015-05-20 |
| BR112015000798A2 (pt) | 2017-06-27 |
| US20140154253A1 (en) | 2014-06-05 |
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