CA2288994C - Polyalkylene oxide-modified single chain polypeptides - Google Patents
Polyalkylene oxide-modified single chain polypeptides Download PDFInfo
- Publication number
- CA2288994C CA2288994C CA2288994A CA2288994A CA2288994C CA 2288994 C CA2288994 C CA 2288994C CA 2288994 A CA2288994 A CA 2288994A CA 2288994 A CA2288994 A CA 2288994A CA 2288994 C CA2288994 C CA 2288994C
- Authority
- CA
- Canada
- Prior art keywords
- antigen
- polypeptide
- chain
- binding
- variable region
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
- C07K2317/41—Glycosylation, sialylation, or fucosylation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
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US4444997P | 1997-04-30 | 1997-04-30 | |
US5047297P | 1997-06-23 | 1997-06-23 | |
US6307497P | 1997-10-27 | 1997-10-27 | |
US6734197P | 1997-12-02 | 1997-12-02 | |
US60/063,074 | 1997-12-02 | ||
US60/044,449 | 1997-12-02 | ||
US60/067,341 | 1997-12-02 | ||
US60/050,472 | 1997-12-02 | ||
PCT/US1998/008654 WO1998048837A1 (en) | 1997-04-30 | 1998-04-30 | Polyalkylene oxide-modified single chain polypeptides |
Publications (2)
Publication Number | Publication Date |
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CA2288994A1 CA2288994A1 (en) | 1998-11-05 |
CA2288994C true CA2288994C (en) | 2011-07-05 |
Family
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Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
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CA2288994A Expired - Lifetime CA2288994C (en) | 1997-04-30 | 1998-04-30 | Polyalkylene oxide-modified single chain polypeptides |
CA2288992A Expired - Lifetime CA2288992C (en) | 1997-04-30 | 1998-04-30 | Single-chain antigen-binding proteins capable of glycosylation, production and uses thereof |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2288992A Expired - Lifetime CA2288992C (en) | 1997-04-30 | 1998-04-30 | Single-chain antigen-binding proteins capable of glycosylation, production and uses thereof |
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EP0979102A4 (en) | 2005-11-23 |
US20020155498A1 (en) | 2002-10-24 |
US6323322B1 (en) | 2001-11-27 |
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JP4187277B2 (ja) | 2008-11-26 |
EP0981548A1 (en) | 2000-03-01 |
JP2008115193A (ja) | 2008-05-22 |
JP2002516610A (ja) | 2002-06-04 |
US7632504B2 (en) | 2009-12-15 |
JP2002505574A (ja) | 2002-02-19 |
US20050008650A1 (en) | 2005-01-13 |
US20050048064A1 (en) | 2005-03-03 |
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