CA2228048A1 - Procede de preparation de formes galeniques solides de medicaments en tres faibles doses - Google Patents
Procede de preparation de formes galeniques solides de medicaments en tres faibles doses Download PDFInfo
- Publication number
- CA2228048A1 CA2228048A1 CA002228048A CA2228048A CA2228048A1 CA 2228048 A1 CA2228048 A1 CA 2228048A1 CA 002228048 A CA002228048 A CA 002228048A CA 2228048 A CA2228048 A CA 2228048A CA 2228048 A1 CA2228048 A1 CA 2228048A1
- Authority
- CA
- Canada
- Prior art keywords
- composition according
- drug
- alpha
- carrier
- daily dose
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Cette invention concerne un procédé de formulation d'un médicament qui consiste à mélanger des particules d'excipient à une solution aqueuse contenant un médicament, ladite solution représentant de 1 à 3 % en poids du mélange total. L'invention concerne également un procédé de traitement et/ou de prophylaxie de la démence qui consiste à administrer à un patient du monochlorhydrate de [R-(Z)]-.alpha.-(méthoxyimino)-.alpha.-(1-azabicyclo[2.2.2]oct-3-yl)acétonitrile en une dose quotidienne ne dépassant pas 0,01mg/kg, ainsi que les compositions pharmaceutiques utilisées dans ce type de traitement.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9515624.6 | 1995-07-29 | ||
GBGB9515624.6A GB9515624D0 (en) | 1995-07-29 | 1995-07-29 | Novel process |
GB9606684.0 | 1996-03-29 | ||
GBGB9606684.0A GB9606684D0 (en) | 1996-03-29 | 1996-03-29 | Novel process |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2228048A1 true CA2228048A1 (fr) | 1997-02-13 |
Family
ID=26307485
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002228048A Abandoned CA2228048A1 (fr) | 1995-07-29 | 1996-07-29 | Procede de preparation de formes galeniques solides de medicaments en tres faibles doses |
Country Status (25)
Country | Link |
---|---|
EP (1) | EP0841902A2 (fr) |
JP (1) | JPH11510493A (fr) |
KR (1) | KR19990035972A (fr) |
CN (1) | CN1196677A (fr) |
AP (1) | AP858A (fr) |
AR (1) | AR004178A1 (fr) |
AU (1) | AU716961B2 (fr) |
BG (1) | BG102266A (fr) |
BR (1) | BR9609804A (fr) |
CA (1) | CA2228048A1 (fr) |
CZ (1) | CZ24798A3 (fr) |
DZ (1) | DZ2077A1 (fr) |
EA (2) | EA199901055A1 (fr) |
HU (1) | HUP9900521A3 (fr) |
IL (1) | IL122897A0 (fr) |
MA (1) | MA23953A1 (fr) |
MX (1) | MX9800809A (fr) |
NO (1) | NO980384L (fr) |
NZ (1) | NZ315632A (fr) |
OA (1) | OA10659A (fr) |
PL (1) | PL325242A1 (fr) |
SK (1) | SK11098A3 (fr) |
TR (1) | TR199800156T1 (fr) |
UY (1) | UY24297A1 (fr) |
WO (1) | WO1997004750A2 (fr) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9619074D0 (en) * | 1996-09-12 | 1996-10-23 | Smithkline Beecham Plc | Composition |
AU748396C (en) * | 1998-03-11 | 2003-01-23 | Smithkline Beecham Corporation | Composition |
FR2796840B1 (fr) * | 1999-07-26 | 2003-06-20 | Ethypharm Lab Prod Ethiques | Comprimes faiblement doses et procede de preparation |
BRPI0116793B8 (pt) | 2000-12-14 | 2021-05-25 | Johnson & Johnson | produtos de hormônio de esteróide e métodos para prepará-los |
WO2005097076A2 (fr) * | 2004-04-09 | 2005-10-20 | Smithkline Beecham Corporation | Produits pharmaceutiques a faibles doses |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4489026A (en) * | 1982-09-07 | 1984-12-18 | The Upjohn Company | Process for preparing solid unit dosage forms of ultra-low dose drugs |
JPS5970614A (ja) * | 1982-10-14 | 1984-04-21 | Asahi Chem Ind Co Ltd | 微量主薬系湿式固形製剤方法 |
US4898736A (en) * | 1988-03-09 | 1990-02-06 | Merck & Co., Inc. | Method for tablet preparation |
SG48315A1 (en) * | 1989-04-13 | 1998-04-17 | Beecham Group Plc | Novel compounds |
ZA939565B (en) * | 1993-12-21 | 1994-08-11 | Applied Analytical Ind Inc | Method for preparing low dose pharmaceutical products. |
-
1996
- 1996-07-25 AR ARP960103748A patent/AR004178A1/es not_active Application Discontinuation
- 1996-07-26 MA MA24329A patent/MA23953A1/fr unknown
- 1996-07-26 UY UY24297A patent/UY24297A1/es not_active IP Right Cessation
- 1996-07-27 DZ DZ960121A patent/DZ2077A1/fr active
- 1996-07-29 EP EP96927621A patent/EP0841902A2/fr not_active Withdrawn
- 1996-07-29 IL IL12289796A patent/IL122897A0/xx unknown
- 1996-07-29 SK SK110-98A patent/SK11098A3/sk unknown
- 1996-07-29 JP JP9507243A patent/JPH11510493A/ja active Pending
- 1996-07-29 WO PCT/EP1996/003326 patent/WO1997004750A2/fr not_active Application Discontinuation
- 1996-07-29 TR TR1998/00156T patent/TR199800156T1/xx unknown
- 1996-07-29 NZ NZ315632A patent/NZ315632A/xx unknown
- 1996-07-29 HU HU9900521A patent/HUP9900521A3/hu unknown
- 1996-07-29 AU AU67384/96A patent/AU716961B2/en not_active Ceased
- 1996-07-29 PL PL96325242A patent/PL325242A1/xx unknown
- 1996-07-29 KR KR1019980700633A patent/KR19990035972A/ko not_active Application Discontinuation
- 1996-07-29 CZ CZ98247A patent/CZ24798A3/cs unknown
- 1996-07-29 MX MX9800809A patent/MX9800809A/es unknown
- 1996-07-29 CN CN96197054A patent/CN1196677A/zh active Pending
- 1996-07-29 BR BR9609804A patent/BR9609804A/pt not_active Application Discontinuation
- 1996-07-29 EA EA199901055A patent/EA199901055A1/ru unknown
- 1996-07-29 AP APAP/P/1998/001170A patent/AP858A/en active
- 1996-07-29 CA CA002228048A patent/CA2228048A1/fr not_active Abandoned
- 1996-07-29 EA EA199800179A patent/EA000740B1/ru not_active IP Right Cessation
-
1998
- 1998-01-28 OA OA9800013A patent/OA10659A/en unknown
- 1998-01-28 NO NO980384A patent/NO980384L/no unknown
- 1998-02-20 BG BG102266A patent/BG102266A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
CZ24798A3 (cs) | 1998-06-17 |
MA23953A1 (fr) | 1997-04-01 |
NO980384L (no) | 1998-03-26 |
NZ315632A (en) | 1999-11-29 |
HUP9900521A3 (en) | 2001-04-28 |
JPH11510493A (ja) | 1999-09-14 |
AU6738496A (en) | 1997-02-26 |
HUP9900521A2 (hu) | 1999-06-28 |
WO1997004750A2 (fr) | 1997-02-13 |
AP9801170A0 (en) | 1998-01-31 |
MX9800809A (es) | 1998-04-30 |
DZ2077A1 (fr) | 2002-07-22 |
PL325242A1 (en) | 1998-07-06 |
IL122897A0 (en) | 1998-08-16 |
OA10659A (en) | 2002-09-18 |
BR9609804A (pt) | 1999-07-06 |
AU716961B2 (en) | 2000-03-09 |
AP858A (en) | 2000-07-12 |
TR199800156T1 (xx) | 1998-04-21 |
KR19990035972A (ko) | 1999-05-25 |
CN1196677A (zh) | 1998-10-21 |
EA000740B1 (ru) | 2000-02-28 |
EA199901055A1 (ru) | 2000-06-26 |
AR004178A1 (es) | 1998-11-04 |
UY24297A1 (es) | 1997-01-23 |
NO980384D0 (no) | 1998-01-28 |
EP0841902A2 (fr) | 1998-05-20 |
EA199800179A1 (ru) | 1998-10-29 |
BG102266A (en) | 1998-10-30 |
SK11098A3 (en) | 1998-07-08 |
WO1997004750A3 (fr) | 1997-03-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Discontinued |