AU6738496A - Process for preparing solid dosage forms of very low-dose drugs - Google Patents

Process for preparing solid dosage forms of very low-dose drugs

Info

Publication number
AU6738496A
AU6738496A AU67384/96A AU6738496A AU6738496A AU 6738496 A AU6738496 A AU 6738496A AU 67384/96 A AU67384/96 A AU 67384/96A AU 6738496 A AU6738496 A AU 6738496A AU 6738496 A AU6738496 A AU 6738496A
Authority
AU
Australia
Prior art keywords
low
dosage forms
solid dosage
preparing solid
dose drugs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU67384/96A
Other versions
AU716961B2 (en
Inventor
Michael Sidney George Clark
Rajinder Kumar
Julia Mary Loudon
Sultan James Manek
Neil Mortimer
James Albert Napper
Karen Triona O'brien
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9515624.6A external-priority patent/GB9515624D0/en
Priority claimed from GBGB9606684.0A external-priority patent/GB9606684D0/en
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Publication of AU6738496A publication Critical patent/AU6738496A/en
Application granted granted Critical
Publication of AU716961B2 publication Critical patent/AU716961B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
AU67384/96A 1995-07-29 1996-07-29 Process for preparing solid dosage forms of very low-dose drugs Ceased AU716961B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB9515624 1995-07-29
GBGB9515624.6A GB9515624D0 (en) 1995-07-29 1995-07-29 Novel process
GB9606684 1996-03-29
GBGB9606684.0A GB9606684D0 (en) 1996-03-29 1996-03-29 Novel process
PCT/EP1996/003326 WO1997004750A2 (en) 1995-07-29 1996-07-29 Process for preparing solid dosage forms of very low-dose drugs

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU20640/00A Division AU751607B2 (en) 1995-07-29 2000-03-03 Method of treatment of dementia

Publications (2)

Publication Number Publication Date
AU6738496A true AU6738496A (en) 1997-02-26
AU716961B2 AU716961B2 (en) 2000-03-09

Family

ID=26307485

Family Applications (1)

Application Number Title Priority Date Filing Date
AU67384/96A Ceased AU716961B2 (en) 1995-07-29 1996-07-29 Process for preparing solid dosage forms of very low-dose drugs

Country Status (25)

Country Link
EP (1) EP0841902A2 (en)
JP (1) JPH11510493A (en)
KR (1) KR19990035972A (en)
CN (1) CN1196677A (en)
AP (1) AP858A (en)
AR (1) AR004178A1 (en)
AU (1) AU716961B2 (en)
BG (1) BG102266A (en)
BR (1) BR9609804A (en)
CA (1) CA2228048A1 (en)
CZ (1) CZ24798A3 (en)
DZ (1) DZ2077A1 (en)
EA (2) EA000740B1 (en)
HU (1) HUP9900521A3 (en)
IL (1) IL122897A0 (en)
MA (1) MA23953A1 (en)
MX (1) MX9800809A (en)
NO (1) NO980384L (en)
NZ (1) NZ315632A (en)
OA (1) OA10659A (en)
PL (1) PL325242A1 (en)
SK (1) SK11098A3 (en)
TR (1) TR199800156T1 (en)
UY (1) UY24297A1 (en)
WO (1) WO1997004750A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9619074D0 (en) * 1996-09-12 1996-10-23 Smithkline Beecham Plc Composition
KR20010034588A (en) * 1998-03-11 2001-04-25 피터 기딩스 Composition
FR2796840B1 (en) * 1999-07-26 2003-06-20 Ethypharm Lab Prod Ethiques LOW-DOSE TABLETS AND METHOD OF PREPARATION
DK1591121T3 (en) 2000-12-14 2009-10-05 Ortho Mcneil Janssen Pharm Process for the preparation of steroid hormone products containing a stabilizer in non-crystalline form
JP2007532511A (en) * 2004-04-09 2007-11-15 スミスクライン ビーチャム コーポレーション Low dose medicine

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4489026A (en) * 1982-09-07 1984-12-18 The Upjohn Company Process for preparing solid unit dosage forms of ultra-low dose drugs
JPS5970614A (en) * 1982-10-14 1984-04-21 Asahi Chem Ind Co Ltd Wet solid pharmaceutical preparation of very small amount of main drug
US4898736A (en) * 1988-03-09 1990-02-06 Merck & Co., Inc. Method for tablet preparation
DK0392803T3 (en) * 1989-04-13 2004-10-18 Beecham Group Plc Hitherto unknown compounds
ZA939565B (en) * 1993-12-21 1994-08-11 Applied Analytical Ind Inc Method for preparing low dose pharmaceutical products.

Also Published As

Publication number Publication date
BG102266A (en) 1998-10-30
CZ24798A3 (en) 1998-06-17
NO980384D0 (en) 1998-01-28
OA10659A (en) 2002-09-18
MA23953A1 (en) 1997-04-01
DZ2077A1 (en) 2002-07-22
EA199800179A1 (en) 1998-10-29
SK11098A3 (en) 1998-07-08
CN1196677A (en) 1998-10-21
WO1997004750A2 (en) 1997-02-13
CA2228048A1 (en) 1997-02-13
AR004178A1 (en) 1998-11-04
PL325242A1 (en) 1998-07-06
NO980384L (en) 1998-03-26
AP858A (en) 2000-07-12
TR199800156T1 (en) 1998-04-21
EP0841902A2 (en) 1998-05-20
HUP9900521A3 (en) 2001-04-28
EA000740B1 (en) 2000-02-28
WO1997004750A3 (en) 1997-03-27
EA199901055A1 (en) 2000-06-26
MX9800809A (en) 1998-04-30
AP9801170A0 (en) 1998-01-31
BR9609804A (en) 1999-07-06
NZ315632A (en) 1999-11-29
IL122897A0 (en) 1998-08-16
AU716961B2 (en) 2000-03-09
HUP9900521A2 (en) 1999-06-28
JPH11510493A (en) 1999-09-14
KR19990035972A (en) 1999-05-25
UY24297A1 (en) 1997-01-23

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired