OA10659A - Process for preparing solid dosage forms of very low-dose drugs - Google Patents

Process for preparing solid dosage forms of very low-dose drugs Download PDF

Info

Publication number
OA10659A
OA10659A OA9800013A OA9800013A OA10659A OA 10659 A OA10659 A OA 10659A OA 9800013 A OA9800013 A OA 9800013A OA 9800013 A OA9800013 A OA 9800013A OA 10659 A OA10659 A OA 10659A
Authority
OA
OAPI
Prior art keywords
composition according
drug
carrier
pharmaceutical composition
daily dose
Prior art date
Application number
OA9800013A
Other languages
English (en)
Inventor
James Albert Napper
Karen Triona O'brien
Sultan James Manek
Rajinder Kumar
Julia Mary Loudon
Michael Sydney George Clark
Neil Mortimer
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9515624.6A external-priority patent/GB9515624D0/en
Priority claimed from GBGB9606684.0A external-priority patent/GB9606684D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of OA10659A publication Critical patent/OA10659A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
OA9800013A 1995-07-29 1998-01-28 Process for preparing solid dosage forms of very low-dose drugs OA10659A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9515624.6A GB9515624D0 (en) 1995-07-29 1995-07-29 Novel process
GBGB9606684.0A GB9606684D0 (en) 1996-03-29 1996-03-29 Novel process

Publications (1)

Publication Number Publication Date
OA10659A true OA10659A (en) 2002-09-18

Family

ID=26307485

Family Applications (1)

Application Number Title Priority Date Filing Date
OA9800013A OA10659A (en) 1995-07-29 1998-01-28 Process for preparing solid dosage forms of very low-dose drugs

Country Status (25)

Country Link
EP (1) EP0841902A2 (fr)
JP (1) JPH11510493A (fr)
KR (1) KR19990035972A (fr)
CN (1) CN1196677A (fr)
AP (1) AP858A (fr)
AR (1) AR004178A1 (fr)
AU (1) AU716961B2 (fr)
BG (1) BG102266A (fr)
BR (1) BR9609804A (fr)
CA (1) CA2228048A1 (fr)
CZ (1) CZ24798A3 (fr)
DZ (1) DZ2077A1 (fr)
EA (2) EA000740B1 (fr)
HU (1) HUP9900521A3 (fr)
IL (1) IL122897A0 (fr)
MA (1) MA23953A1 (fr)
MX (1) MX9800809A (fr)
NO (1) NO980384L (fr)
NZ (1) NZ315632A (fr)
OA (1) OA10659A (fr)
PL (1) PL325242A1 (fr)
SK (1) SK11098A3 (fr)
TR (1) TR199800156T1 (fr)
UY (1) UY24297A1 (fr)
WO (1) WO1997004750A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9619074D0 (en) * 1996-09-12 1996-10-23 Smithkline Beecham Plc Composition
HUP0101043A3 (en) 1998-03-11 2002-02-28 Smithkline Beecham Corp Controlled release oral dosage form containing [r-(z)]-alpha-(methoxyimino)-alpha-(1-azabicyclo[2.2.2]oct-3-yl]acetonitrile monohydrochlorid and process for its preparation
FR2796840B1 (fr) * 1999-07-26 2003-06-20 Ethypharm Lab Prod Ethiques Comprimes faiblement doses et procede de preparation
UA77404C2 (en) 2000-12-14 2006-12-15 Ortho Mcneil Pharm Inc Norgestimate-based steroid hormone product and method for its manufacture
WO2005097076A2 (fr) * 2004-04-09 2005-10-20 Smithkline Beecham Corporation Produits pharmaceutiques a faibles doses

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4489026A (en) * 1982-09-07 1984-12-18 The Upjohn Company Process for preparing solid unit dosage forms of ultra-low dose drugs
JPS5970614A (ja) * 1982-10-14 1984-04-21 Asahi Chem Ind Co Ltd 微量主薬系湿式固形製剤方法
US4898736A (en) * 1988-03-09 1990-02-06 Merck & Co., Inc. Method for tablet preparation
SG48315A1 (en) * 1989-04-13 1998-04-17 Beecham Group Plc Novel compounds
ZA939565B (en) * 1993-12-21 1994-08-11 Applied Analytical Ind Inc Method for preparing low dose pharmaceutical products.

Also Published As

Publication number Publication date
KR19990035972A (ko) 1999-05-25
HUP9900521A3 (en) 2001-04-28
IL122897A0 (en) 1998-08-16
WO1997004750A3 (fr) 1997-03-27
CA2228048A1 (fr) 1997-02-13
AU6738496A (en) 1997-02-26
NZ315632A (en) 1999-11-29
AU716961B2 (en) 2000-03-09
TR199800156T1 (xx) 1998-04-21
CZ24798A3 (cs) 1998-06-17
UY24297A1 (es) 1997-01-23
AP9801170A0 (en) 1998-01-31
HUP9900521A2 (hu) 1999-06-28
NO980384L (no) 1998-03-26
JPH11510493A (ja) 1999-09-14
BR9609804A (pt) 1999-07-06
EA199901055A1 (ru) 2000-06-26
BG102266A (en) 1998-10-30
EA199800179A1 (ru) 1998-10-29
EA000740B1 (ru) 2000-02-28
EP0841902A2 (fr) 1998-05-20
MA23953A1 (fr) 1997-04-01
WO1997004750A2 (fr) 1997-02-13
AR004178A1 (es) 1998-11-04
DZ2077A1 (fr) 2002-07-22
CN1196677A (zh) 1998-10-21
PL325242A1 (en) 1998-07-06
SK11098A3 (en) 1998-07-08
MX9800809A (es) 1998-04-30
AP858A (en) 2000-07-12
NO980384D0 (no) 1998-01-28

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