NZ315632A - Process for preparing solid dosage forms of very low-dose drugs comprising admixing 1-3% by weight of carrier particles with a solution of drug in water - Google Patents

Process for preparing solid dosage forms of very low-dose drugs comprising admixing 1-3% by weight of carrier particles with a solution of drug in water

Info

Publication number
NZ315632A
NZ315632A NZ315632A NZ31563296A NZ315632A NZ 315632 A NZ315632 A NZ 315632A NZ 315632 A NZ315632 A NZ 315632A NZ 31563296 A NZ31563296 A NZ 31563296A NZ 315632 A NZ315632 A NZ 315632A
Authority
NZ
New Zealand
Prior art keywords
solution
drug
weight
water
carrier particles
Prior art date
Application number
NZ315632A
Other languages
English (en)
Inventor
James Albert Napper
Karen Triona O'brien
Sultan James Manek
Rajinder Kumar
Julia Mary Loudon
Michael Sidney George Clark
Neil Mortimer
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9515624.6A external-priority patent/GB9515624D0/en
Priority claimed from GBGB9606684.0A external-priority patent/GB9606684D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of NZ315632A publication Critical patent/NZ315632A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NZ315632A 1995-07-29 1996-07-29 Process for preparing solid dosage forms of very low-dose drugs comprising admixing 1-3% by weight of carrier particles with a solution of drug in water NZ315632A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9515624.6A GB9515624D0 (en) 1995-07-29 1995-07-29 Novel process
GBGB9606684.0A GB9606684D0 (en) 1996-03-29 1996-03-29 Novel process
PCT/EP1996/003326 WO1997004750A2 (en) 1995-07-29 1996-07-29 Process for preparing solid dosage forms of very low-dose drugs

Publications (1)

Publication Number Publication Date
NZ315632A true NZ315632A (en) 1999-11-29

Family

ID=26307485

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ315632A NZ315632A (en) 1995-07-29 1996-07-29 Process for preparing solid dosage forms of very low-dose drugs comprising admixing 1-3% by weight of carrier particles with a solution of drug in water

Country Status (25)

Country Link
EP (1) EP0841902A2 (xx)
JP (1) JPH11510493A (xx)
KR (1) KR19990035972A (xx)
CN (1) CN1196677A (xx)
AP (1) AP858A (xx)
AR (1) AR004178A1 (xx)
AU (1) AU716961B2 (xx)
BG (1) BG102266A (xx)
BR (1) BR9609804A (xx)
CA (1) CA2228048A1 (xx)
CZ (1) CZ24798A3 (xx)
DZ (1) DZ2077A1 (xx)
EA (2) EA000740B1 (xx)
HU (1) HUP9900521A3 (xx)
IL (1) IL122897A0 (xx)
MA (1) MA23953A1 (xx)
MX (1) MX9800809A (xx)
NO (1) NO980384L (xx)
NZ (1) NZ315632A (xx)
OA (1) OA10659A (xx)
PL (1) PL325242A1 (xx)
SK (1) SK11098A3 (xx)
TR (1) TR199800156T1 (xx)
UY (1) UY24297A1 (xx)
WO (1) WO1997004750A2 (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9619074D0 (en) * 1996-09-12 1996-10-23 Smithkline Beecham Plc Composition
CA2323177A1 (en) 1998-03-11 1999-09-16 Susan Marie Milosovich Composition
FR2796840B1 (fr) * 1999-07-26 2003-06-20 Ethypharm Lab Prod Ethiques Comprimes faiblement doses et procede de preparation
AU2742102A (en) 2000-12-14 2002-06-24 Ortho Mcneil Pharm Inc Steroid hormone products and methods for preparing them
US20070202179A1 (en) * 2004-04-09 2007-08-30 FAULKNER Patrick Low Dose Pharmaceutical Products

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4489026A (en) * 1982-09-07 1984-12-18 The Upjohn Company Process for preparing solid unit dosage forms of ultra-low dose drugs
JPS5970614A (ja) * 1982-10-14 1984-04-21 Asahi Chem Ind Co Ltd 微量主薬系湿式固形製剤方法
US4898736A (en) * 1988-03-09 1990-02-06 Merck & Co., Inc. Method for tablet preparation
ES2219636T3 (es) * 1989-04-13 2004-12-01 Beecham Group P.L.C. Nuevos compuestos.
ZA939565B (en) * 1993-12-21 1994-08-11 Applied Analytical Ind Inc Method for preparing low dose pharmaceutical products.

Also Published As

Publication number Publication date
NO980384D0 (no) 1998-01-28
JPH11510493A (ja) 1999-09-14
AP9801170A0 (en) 1998-01-31
SK11098A3 (en) 1998-07-08
BR9609804A (pt) 1999-07-06
HUP9900521A2 (hu) 1999-06-28
AR004178A1 (es) 1998-11-04
IL122897A0 (en) 1998-08-16
WO1997004750A3 (en) 1997-03-27
EA199800179A1 (ru) 1998-10-29
EP0841902A2 (en) 1998-05-20
EA000740B1 (ru) 2000-02-28
CA2228048A1 (en) 1997-02-13
BG102266A (en) 1998-10-30
AP858A (en) 2000-07-12
EA199901055A1 (ru) 2000-06-26
MX9800809A (es) 1998-04-30
WO1997004750A2 (en) 1997-02-13
CN1196677A (zh) 1998-10-21
MA23953A1 (fr) 1997-04-01
AU716961B2 (en) 2000-03-09
TR199800156T1 (xx) 1998-04-21
KR19990035972A (ko) 1999-05-25
NO980384L (no) 1998-03-26
OA10659A (en) 2002-09-18
AU6738496A (en) 1997-02-26
DZ2077A1 (fr) 2002-07-22
PL325242A1 (en) 1998-07-06
HUP9900521A3 (en) 2001-04-28
UY24297A1 (es) 1997-01-23
CZ24798A3 (cs) 1998-06-17

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