BRPI0407149A - Formas polimórficas de rifaximin, processos para sua produção e seu uso em preparações medicinais - Google Patents

Formas polimórficas de rifaximin, processos para sua produção e seu uso em preparações medicinais

Info

Publication number
BRPI0407149A
BRPI0407149A BR0407149-2A BRPI0407149A BRPI0407149A BR PI0407149 A BRPI0407149 A BR PI0407149A BR PI0407149 A BRPI0407149 A BR PI0407149A BR PI0407149 A BRPI0407149 A BR PI0407149A
Authority
BR
Brazil
Prior art keywords
rifaximin
production
polymorphic forms
processes
medicinal preparations
Prior art date
Application number
BR0407149-2A
Other languages
English (en)
Inventor
Giuseppe C Viscomi
Manuela Campana
Dario Braga
Donatella Confortini
Vincenzo Cannata
Paolo Righi
Goffredo Rosini
Original Assignee
Alfa Wassermann Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33187382&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0407149(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alfa Wassermann Spa filed Critical Alfa Wassermann Spa
Publication of BRPI0407149A publication Critical patent/BRPI0407149A/pt
Publication of BRPI0407149A8 publication Critical patent/BRPI0407149A8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05B—ELECTRIC HEATING; ELECTRIC LIGHT SOURCES NOT OTHERWISE PROVIDED FOR; CIRCUIT ARRANGEMENTS FOR ELECTRIC LIGHT SOURCES, IN GENERAL
    • H05B6/00—Heating by electric, magnetic or electromagnetic fields
    • H05B6/02—Induction heating
    • H05B6/10—Induction heating apparatus, other than furnaces, for specific applications
    • H05B6/12—Cooking devices
    • H05B6/1209—Cooking devices induction cooking plates or the like and devices to be used in combination with them
    • H05B6/1236—Cooking devices induction cooking plates or the like and devices to be used in combination with them adapted to induce current in a coil to supply power to a device and electrical heating devices powered in this way
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05B—ELECTRIC HEATING; ELECTRIC LIGHT SOURCES NOT OTHERWISE PROVIDED FOR; CIRCUIT ARRANGEMENTS FOR ELECTRIC LIGHT SOURCES, IN GENERAL
    • H05B6/00—Heating by electric, magnetic or electromagnetic fields
    • H05B6/02—Induction heating
    • H05B6/10—Induction heating apparatus, other than furnaces, for specific applications
    • H05B6/12—Cooking devices
    • H05B6/1209—Cooking devices induction cooking plates or the like and devices to be used in combination with them
    • H05B6/1245—Cooking devices induction cooking plates or the like and devices to be used in combination with them with special coil arrangements
    • H05B6/1263—Cooking devices induction cooking plates or the like and devices to be used in combination with them with special coil arrangements using coil cooling arrangements

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Physics & Mathematics (AREA)
  • Electromagnetism (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)

Abstract

"FORMAS POLIMóRFICAS DE RIFAXIMIN, PROCESSOS PARA SUA PRODUçãO E SEU USO EM PREPARAçõES MEDICINAIS". A presente invenção refere-se a formas polimórficas cristalinas de rifaximin (INN), referidas como rifaximin alfa e rifaximin beta, e a uma forma pobremente cristalina referida como rifaximin gama, úteis na produção de medicamentos contendo rifaximin para o uso oral e tópico e obtidas por meio de um processo de cristalização realizado por dissolução quente de rifaximin bruto em álcool etílico e causando a cristalização do produto pela adição de água em uma temperatura fixada e por um período de tempo fixado, seguido por secagem sob condições controladas até atingir um preciso teor de água no produto final, são os objetos da invenção.
BRPI0407149A 2003-11-07 2004-11-04 formas polimórficas de rifaximin, processos para sua produção e seu uso em preparações medicinais BRPI0407149A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT002144A ITMI20032144A1 (it) 2003-11-07 2003-11-07 Forme polimorfe di rifaximina, processi per ottenerle e
PCT/EP2004/012490 WO2005044823A2 (en) 2003-11-07 2004-11-04 Polymorphous forms of rifaximin as antibiotics

Publications (2)

Publication Number Publication Date
BRPI0407149A true BRPI0407149A (pt) 2006-02-07
BRPI0407149A8 BRPI0407149A8 (pt) 2019-01-15

Family

ID=33187382

Family Applications (2)

Application Number Title Priority Date Filing Date
BR0402382-0A BRPI0402382A (pt) 2003-11-07 2004-03-19 Formas polimórficas de rifaximina, processos para a produção das mesmas e uso das mesmas em preparações medicinais
BRPI0407149A BRPI0407149A8 (pt) 2003-11-07 2004-11-04 formas polimórficas de rifaximin, processos para sua produção e seu uso em preparações medicinais

Family Applications Before (1)

Application Number Title Priority Date Filing Date
BR0402382-0A BRPI0402382A (pt) 2003-11-07 2004-03-19 Formas polimórficas de rifaximina, processos para a produção das mesmas e uso das mesmas em preparações medicinais

Country Status (38)

Country Link
US (5) US7045620B2 (pt)
EP (6) EP1676847B1 (pt)
JP (5) JP2005139161A (pt)
KR (4) KR20050043589A (pt)
CN (4) CN1613858A (pt)
AR (3) AR043547A1 (pt)
AT (3) ATE421966T1 (pt)
AU (2) AU2004200964A1 (pt)
BR (2) BRPI0402382A (pt)
CA (2) CA2460384A1 (pt)
CL (1) CL2004000498A1 (pt)
CO (1) CO5560083A1 (pt)
CY (3) CY1108017T1 (pt)
DE (4) DE04005541T1 (pt)
DK (3) DK1676848T3 (pt)
ES (3) ES2320160T4 (pt)
HK (3) HK1092151A1 (pt)
HR (2) HRP20040265A2 (pt)
IL (2) IL160798A0 (pt)
IT (1) ITMI20032144A1 (pt)
JO (1) JO2470B1 (pt)
MA (1) MA27069A1 (pt)
MD (1) MD3653G8 (pt)
ME (1) ME00424B (pt)
MX (2) MXPA04002353A (pt)
NO (1) NO334950B1 (pt)
NZ (1) NZ531622A (pt)
PL (3) PL1676847T3 (pt)
PT (3) PT1676848E (pt)
RS (4) RS20060168A (pt)
RU (1) RU2270200C2 (pt)
SI (3) SI1676848T1 (pt)
TN (2) TNSN04044A1 (pt)
TW (1) TWI285107B (pt)
UA (1) UA86384C2 (pt)
WO (1) WO2005044823A2 (pt)
YU (1) YU24804A (pt)
ZA (1) ZA200401948B (pt)

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KR100855084B1 (ko) 2008-08-29
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JP2011057698A (ja) 2011-03-24
JP5199576B2 (ja) 2013-05-15
DE602004006367D1 (de) 2007-06-21
HRP20060093A2 (en) 2006-05-31
ATE361927T1 (de) 2007-06-15
RS54569B1 (en) 2016-06-30
AR043547A1 (es) 2005-08-03
EP1676847A1 (en) 2006-07-05
EP1557421B1 (en) 2007-05-09
KR20070113327A (ko) 2007-11-28
AU2004287601B8 (en) 2009-03-05
KR20050043589A (ko) 2005-05-11
IL174271A0 (en) 2006-08-01
HK1073657A1 (en) 2005-10-14
US20110160449A1 (en) 2011-06-30
AU2004200964A1 (en) 2005-05-26
PL1557421T3 (pl) 2007-08-31
JO2470B1 (en) 2009-01-20
NO334950B1 (no) 2014-08-04
CA2538546A1 (en) 2005-05-19
JP2014177500A (ja) 2014-09-25
DE602004006367T2 (de) 2007-09-06
NZ531622A (en) 2004-10-29
PL1676847T3 (pl) 2009-07-31
ITMI20032144A1 (it) 2005-05-08
US20080132530A1 (en) 2008-06-05
PT1676848E (pt) 2009-04-09
CN1613858A (zh) 2005-05-11
AU2004287601B2 (en) 2009-02-26
DK1676848T3 (da) 2009-05-11
DE602004019298D1 (de) 2009-03-19
US8404704B2 (en) 2013-03-26
NO20061110L (no) 2006-04-19
DK1557421T3 (da) 2007-09-17
ES2320160T3 (es) 2009-05-19
HRP20040265A2 (en) 2004-12-31
CY1108017T1 (el) 2013-09-04
YU24804A (sh) 2006-08-17
MD20060080A (en) 2006-11-30
KR100883216B1 (ko) 2009-02-13
RS54568B1 (en) 2016-06-30
ES2320160T4 (es) 2011-03-09
KR20060110737A (ko) 2006-10-25
PL1676848T3 (pl) 2009-07-31
WO2005044823A3 (en) 2005-10-27
EP2208730A1 (en) 2010-07-21
IL174271A (en) 2010-12-30
RS54571B1 (en) 2016-06-30
DE602004006367C5 (de) 2019-04-04
ES2244364T3 (es) 2007-12-01
CA2460384A1 (en) 2005-05-07
JP2011046738A (ja) 2011-03-10
CA2538546C (en) 2011-04-19
CY1108964T1 (el) 2014-07-02
KR20070113326A (ko) 2007-11-28
CN101260115B (zh) 2011-11-23
RS20150291A1 (en) 2015-10-30
CN101260115A (zh) 2008-09-10
US8173801B2 (en) 2012-05-08
ATE421966T1 (de) 2009-02-15
RS20060168A (en) 2008-09-29
US7045620B2 (en) 2006-05-16
ATE421965T1 (de) 2009-02-15
RU2004108953A (ru) 2005-10-27
IL160798A0 (en) 2004-08-31
SI1557421T1 (sl) 2007-08-31
PT1676847E (pt) 2009-04-09
ES2244364T1 (es) 2005-12-16
EP1682556A2 (en) 2006-07-26
HK1092150A1 (en) 2007-02-02
BRPI0402382A (pt) 2005-06-28
CN101260114A (zh) 2008-09-10
WO2005044823A2 (en) 2005-05-19
RS20150292A1 (en) 2015-10-30
HK1092151A1 (en) 2007-02-02
EP1676848B1 (en) 2009-01-28
US20120059023A1 (en) 2012-03-08
JP5635376B2 (ja) 2014-12-03
TNSN06069A1 (en) 2007-10-03
CN1886408B (zh) 2010-06-09
AR081991A2 (es) 2012-10-31
CL2004000498A1 (es) 2005-03-11
CY1108909T1 (el) 2014-07-02
TWI285107B (en) 2007-08-11
EP1676847B1 (en) 2009-01-28
SI1676847T1 (sl) 2009-06-30
CN1886408A (zh) 2006-12-27
US20050101598A1 (en) 2005-05-12
MD3653G8 (ro) 2016-08-31
EP1676848A1 (en) 2006-07-05
US20050272754A1 (en) 2005-12-08
MA27069A1 (fr) 2004-12-20
KR100867751B1 (ko) 2008-11-10
ES2320161T3 (es) 2009-05-19
MXPA04002353A (es) 2005-05-11
MD3653F2 (en) 2008-07-31
HRP20060093B1 (hr) 2015-12-18
BRPI0407149A8 (pt) 2019-01-15
DE602004019296D1 (de) 2009-03-19
JP2005139161A (ja) 2005-06-02
ZA200401948B (en) 2004-04-29
DE04005541T1 (de) 2005-12-29
SI1676848T1 (sl) 2009-06-30
MXPA06002644A (es) 2006-06-06
CN101260114B (zh) 2012-11-28
EP1557421A1 (en) 2005-07-27
JP2007509904A (ja) 2007-04-19
RU2270200C2 (ru) 2006-02-20
TW200515913A (en) 2005-05-16
PT1557421E (pt) 2007-07-31
US7915275B2 (en) 2011-03-29
ME00424B (me) 2011-10-10
DK1676847T3 (da) 2009-05-11
UA86384C2 (uk) 2009-04-27
EP2210893A1 (en) 2010-07-28
AR081992A2 (es) 2012-10-31
CO5560083A1 (es) 2005-09-30

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