YU24804A - Polimorfni oblici rifaksimina, postupci za njegovu proizvodnju i njegova upotreba u medicinskim preparatima - Google Patents
Polimorfni oblici rifaksimina, postupci za njegovu proizvodnju i njegova upotreba u medicinskim preparatimaInfo
- Publication number
- YU24804A YU24804A YU24804A YUP24804A YU24804A YU 24804 A YU24804 A YU 24804A YU 24804 A YU24804 A YU 24804A YU P24804 A YUP24804 A YU P24804A YU 24804 A YU24804 A YU 24804A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- rifaximin
- crystalization
- production
- medicinal preparations
- processes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05B—ELECTRIC HEATING; ELECTRIC LIGHT SOURCES NOT OTHERWISE PROVIDED FOR; CIRCUIT ARRANGEMENTS FOR ELECTRIC LIGHT SOURCES, IN GENERAL
- H05B6/00—Heating by electric, magnetic or electromagnetic fields
- H05B6/02—Induction heating
- H05B6/10—Induction heating apparatus, other than furnaces, for specific applications
- H05B6/12—Cooking devices
- H05B6/1209—Cooking devices induction cooking plates or the like and devices to be used in combination with them
- H05B6/1236—Cooking devices induction cooking plates or the like and devices to be used in combination with them adapted to induce current in a coil to supply power to a device and electrical heating devices powered in this way
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05B—ELECTRIC HEATING; ELECTRIC LIGHT SOURCES NOT OTHERWISE PROVIDED FOR; CIRCUIT ARRANGEMENTS FOR ELECTRIC LIGHT SOURCES, IN GENERAL
- H05B6/00—Heating by electric, magnetic or electromagnetic fields
- H05B6/02—Induction heating
- H05B6/10—Induction heating apparatus, other than furnaces, for specific applications
- H05B6/12—Cooking devices
- H05B6/1209—Cooking devices induction cooking plates or the like and devices to be used in combination with them
- H05B6/1245—Cooking devices induction cooking plates or the like and devices to be used in combination with them with special coil arrangements
- H05B6/1263—Cooking devices induction cooking plates or the like and devices to be used in combination with them with special coil arrangements using coil cooling arrangements
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Physics & Mathematics (AREA)
- Electromagnetism (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicinal Preparation (AREA)
Abstract
Otkriveni su kristalni polimorfni oblici rifaksimin (INN) antibiotika nazvanog rifaksimin α i rifaksimina ГЎ, i slabo kristalni oblik nazvan rifaksimin γ. Ovi oblici su korisni za proizvodnju medicinskih preparata za oralnu i površinsku upotrebu i mogu se dobiti putem postupka kristalizacije obavljenog toplim rastaranjem sirovog rifaksimina u etil alkoholu i uzrokovanjem kristalizacije produkta dodavanjem vode na odredjenoj temperaturi i tokom odredjenog vremenskog perioda. Kristalizacija je praćena sušenjem obavljenim u kontrolisanim uslovima sve dok se ne dostigne specifični sadržaj vode u krajnjem produktu.[Crystal polymorphous forms of rafaximin (INN) antibiotics named as rifaximin α and rifaximin ГЎ, and weak crystal form named rifaximin γ. These forms are useful in production of medicinal preparations for oral and surface use and can be obtained in crystalization process carried out by warm dissolution of raw rifaximin in ethyl alcohol and taking samples of crystalization of the product by adding water at determined temperature and within a determined time period. Crystalization is followed by drying carried in controlled conditions until specific content of water in a final product is obtained.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT002144A ITMI20032144A1 (it) | 2003-11-07 | 2003-11-07 | Forme polimorfe di rifaximina, processi per ottenerle e |
Publications (1)
Publication Number | Publication Date |
---|---|
YU24804A true YU24804A (sh) | 2006-08-17 |
Family
ID=33187382
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU24804A YU24804A (sh) | 2003-11-07 | 2004-03-19 | Polimorfni oblici rifaksimina, postupci za njegovu proizvodnju i njegova upotreba u medicinskim preparatima |
Country Status (38)
Country | Link |
---|---|
US (5) | US7045620B2 (sh) |
EP (6) | EP1676848B1 (sh) |
JP (5) | JP2005139161A (sh) |
KR (4) | KR20050043589A (sh) |
CN (4) | CN1613858A (sh) |
AR (3) | AR043547A1 (sh) |
AT (3) | ATE421965T1 (sh) |
AU (2) | AU2004200964A1 (sh) |
BR (2) | BRPI0402382A (sh) |
CA (2) | CA2460384A1 (sh) |
CL (1) | CL2004000498A1 (sh) |
CO (1) | CO5560083A1 (sh) |
CY (3) | CY1108017T1 (sh) |
DE (4) | DE602004006367C5 (sh) |
DK (3) | DK1557421T3 (sh) |
ES (3) | ES2320160T4 (sh) |
HK (3) | HK1092151A1 (sh) |
HR (2) | HRP20040265A2 (sh) |
IL (2) | IL160798A0 (sh) |
IT (1) | ITMI20032144A1 (sh) |
JO (1) | JO2470B1 (sh) |
MA (1) | MA27069A1 (sh) |
MD (1) | MD3653G8 (sh) |
ME (1) | ME00424B (sh) |
MX (2) | MXPA04002353A (sh) |
NO (1) | NO334950B1 (sh) |
NZ (1) | NZ531622A (sh) |
PL (3) | PL1676848T3 (sh) |
PT (3) | PT1676847E (sh) |
RS (4) | RS20060168A (sh) |
RU (1) | RU2270200C2 (sh) |
SI (3) | SI1676847T1 (sh) |
TN (2) | TNSN04044A1 (sh) |
TW (1) | TWI285107B (sh) |
UA (1) | UA86384C2 (sh) |
WO (1) | WO2005044823A2 (sh) |
YU (1) | YU24804A (sh) |
ZA (1) | ZA200401948B (sh) |
Families Citing this family (82)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7048906B2 (en) | 1995-05-17 | 2006-05-23 | Cedars-Sinai Medical Center | Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions |
US6861053B1 (en) * | 1999-08-11 | 2005-03-01 | Cedars-Sinai Medical Center | Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth |
US7902206B2 (en) * | 2003-11-07 | 2011-03-08 | Alfa Wassermann, S.P.A. | Polymorphic forms α, β and γ of rifaximin |
US7906542B2 (en) * | 2004-11-04 | 2011-03-15 | Alfa Wassermann, S.P.A. | Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin |
ITMI20032144A1 (it) * | 2003-11-07 | 2005-05-08 | Alfa Wassermann Spa | Forme polimorfe di rifaximina, processi per ottenerle e |
US20080262024A1 (en) * | 2003-11-07 | 2008-10-23 | Giuseppe Claudio Viscomi | Rifaximin compositions and method of use |
US7923553B2 (en) * | 2003-11-07 | 2011-04-12 | Alfa Wassermann, S.P.A. | Processes for the production of polymorphic forms of rifaximin |
ES2522895T3 (es) | 2005-03-03 | 2014-11-19 | Alfa Wassermann S.P.A. | Nuevas formas polimorfas de rifaximina, procedimientos para su producción y uso de las mismas en preparados medicinales |
ITBO20050123A1 (it) | 2005-03-07 | 2005-06-06 | Alfa Wassermann Spa | Formulazioni farmaceutiche gastroresistenti contenenti rifaximina |
AU2007281413B2 (en) | 2006-08-02 | 2013-10-31 | Christopher Jahraus | Compositions and methods for the treatment of radiation proctosigmoiditis |
ITMI20061692A1 (it) * | 2006-09-05 | 2008-03-06 | Alfa Wassermann Spa | Uso di polioli per ottenere forme polimorfe stabili di rifaximina |
NZ575550A (en) * | 2006-09-22 | 2011-12-22 | Cipla Ltd | Rifaximin |
US20080161337A1 (en) * | 2007-01-03 | 2008-07-03 | Leonard Weinstock | Use of Rifaximin for the Treatment of Chronic Prostatitis |
US20080159987A1 (en) * | 2007-01-03 | 2008-07-03 | Leonard Weinstock | Use of Rifaximin for the Treatment of Restless Legs Syndrome |
ITMI20071241A1 (it) * | 2007-06-20 | 2008-12-21 | Solmag S P A | Processo per la preparazione di rifaximina amorfa e rifaximina amorfa cosi' ottenuta |
PL2011486T5 (pl) * | 2007-07-06 | 2016-09-30 | Lupin Ltd | Farmaceutyczne kompozycje rifaksyminy |
AU2016203925B2 (en) * | 2007-07-06 | 2016-10-20 | Lupin Limited | Pharmaceutical compositions of rifaximin |
JP5755878B2 (ja) * | 2007-07-06 | 2015-07-29 | ルパン リミテッドLupin Limited | リファキシミンの薬剤組成物 |
US7709634B2 (en) * | 2007-09-20 | 2010-05-04 | Apotex Pharmachem Inc. | Amorphous form of rifaximin and processes for its preparation |
MY158257A (en) * | 2008-02-25 | 2016-09-30 | Salix Pharmaceuticals Ltd | Forms of rifaximin and uses thereof |
US8486956B2 (en) * | 2008-02-25 | 2013-07-16 | Salix Pharmaceuticals, Ltd | Forms of rifaximin and uses thereof |
US11779571B2 (en) | 2008-02-26 | 2023-10-10 | Salix Pharmaceuticals, Inc. | Methods for treating irritable bowel syndrome (IBS) |
DK2252148T3 (da) * | 2008-02-26 | 2019-05-06 | Salix Pharmaceuticals Ltd | Fremgangsmåder til behandling af irritabel tarmsyndrom |
WO2009137672A1 (en) | 2008-05-07 | 2009-11-12 | Salix Pharmaceuticals, Ltd. | Methods of treating bowel disease by administering a bowel cleanser and an antibiotic |
DK2327407T3 (da) | 2008-09-26 | 2014-08-25 | Aska Pharm Co Ltd | Profylaktisk og/eller terapeutisk middel til funktionelle gastrointestinale sygdomme |
US20100317681A1 (en) * | 2009-06-15 | 2010-12-16 | Salix Pharmaceuticals, Ltd. | Modulation of systemic exposure to rifaximin |
PL2350096T3 (pl) | 2008-10-02 | 2020-06-29 | Salix Pharmaceuticals, Ltd. | Sposoby leczenia encefalopatii wątrobowej |
US7928115B2 (en) * | 2008-10-02 | 2011-04-19 | Salix Pharmaceuticals, Ltd. | Methods of treating travelers diarrhea and hepatic encephalopathy |
US20110035232A1 (en) | 2008-10-02 | 2011-02-10 | Salix Pharmaceuticals, Ltd. | Methods of treating hepatic encephalopathy |
KR101906177B1 (ko) | 2008-12-10 | 2018-10-10 | 시플라 리미티드 | 리팍시민 복합체 |
IT1397617B1 (it) * | 2009-04-20 | 2013-01-18 | Alfa Wassermann Spa | Nuovi derivati della rifamicina |
CN102548408A (zh) * | 2009-06-02 | 2012-07-04 | 萨利克斯药品有限公司 | 治疗肝性脑病的方法 |
EP2475392A4 (en) | 2009-09-13 | 2013-01-09 | Salix Pharmaceuticals Ltd | METHOD FOR TREATING IRRITATION SYNDROME |
CN102665693A (zh) * | 2009-10-27 | 2012-09-12 | 鲁平有限公司 | 利福昔明固体分散体 |
WO2011061748A1 (en) * | 2009-11-19 | 2011-05-26 | Strides Arcolab Limited | Rifaximin premix |
JP2013511570A (ja) | 2009-11-23 | 2013-04-04 | シプラ・リミテッド | 局所用泡沫組成物 |
EP2401282B2 (en) † | 2009-12-28 | 2017-01-04 | Silvio Massimo Lavagna | Method for the production of amorphous rifaximin |
WO2011103246A1 (en) | 2010-02-18 | 2011-08-25 | Salix Pharmaceuticals, Ltd. | Methods for treating infection |
IT1398550B1 (it) | 2010-03-05 | 2013-03-01 | Alfa Wassermann Spa | Formulazioni comprendenti rifaximina utili per ottenere un effetto prolungato nel tempo |
NZ603590A (en) * | 2010-06-03 | 2015-08-28 | Salix Pharmaceuticals Ltd | New forms of rifaximin and uses thereof |
WO2011156897A2 (en) * | 2010-06-16 | 2011-12-22 | Apotex Pharmachem Inc. | Polymorphic forms of rifaximin |
SI2593463T1 (sl) | 2010-07-12 | 2020-10-30 | Salix Pharmaceuticals, Inc. | Formulacije rifaksimina in njihove uporabe |
WO2012035544A2 (en) | 2010-09-13 | 2012-03-22 | Sequent Scientific Ltd. | A novel polymorphic form of rifaximin and process for its preparation |
IT1403847B1 (it) * | 2010-09-22 | 2013-11-08 | Alfa Wassermann Spa | Composizioni farmaceutiche comprendenti rifaximina e loro uso. |
WO2012060675A1 (es) * | 2010-11-05 | 2012-05-10 | Interquim, S.A. De C.V. | Proceso para la preparación de rifaximina amorfa |
WO2012076832A1 (en) * | 2010-12-09 | 2012-06-14 | Cipla Limited | Suppositories comprising rifaximin |
AU2012214239B2 (en) * | 2011-02-11 | 2016-06-30 | Salix Pharmaceuticals, Ltd. | Forms of Rifaximin and uses thereof |
EP2705042A1 (en) | 2011-05-02 | 2014-03-12 | Ranbaxy Laboratories Limited | Rifaximin dimethylformamide solvate |
WO2012155981A1 (en) | 2011-05-19 | 2012-11-22 | Friulchem Spa | New process for the synthesis of rifaximin and a new pseudo-crystalline form of rifaximin obtained thereby |
ITMI20110890A1 (it) * | 2011-05-19 | 2012-11-20 | A M S A Anonima Materie Sint & Affini S P A | Polimorfo di rifaximina e processo per la sua preparazione |
ITBO20110461A1 (it) | 2011-07-29 | 2013-01-30 | Alfa Wassermann Spa | Composizioni farmaceutiche comprendenti rifaximina, processi per la loro preparazione e loro uso nel trattamento di infezioni vaginali. |
US20130184302A1 (en) * | 2011-11-02 | 2013-07-18 | Enoch Bortey | Methods for treating irritable bowel syndrome (ibs) and infections |
JP2013184902A (ja) * | 2012-03-06 | 2013-09-19 | Aska Pharmaceutical Co Ltd | リファキシミン含有結晶 |
WO2013185211A1 (en) * | 2012-06-13 | 2013-12-19 | Apotex Pharmachem Inc. | Polymorphic forms of rifaximin |
ITBO20120368A1 (it) | 2012-07-06 | 2014-01-07 | Alfa Wassermann Spa | Composizioni comprendenti rifaximina e amminoacidi, cristalli di rifaximina derivanti da tali composizioni e loro uso. |
WO2014091432A1 (en) | 2012-12-12 | 2014-06-19 | Ranbaxy Laboratories Limited | Pharmaceutical compositions of rifaximin |
WO2014140995A2 (en) | 2013-03-15 | 2014-09-18 | Alfa Wassermann S.P.A. | Method for diagnosing vaginal infections |
US20160038468A1 (en) | 2013-03-15 | 2016-02-11 | Alfa Wassermann S.P.A. | Rifaximin for use in the treating of vaginal infections |
CN105324109A (zh) | 2013-04-12 | 2016-02-10 | 意大利阿尔法韦士曼制药公司 | Nsaid施用和相关的组合物、方法和系统 |
US9018225B1 (en) | 2013-07-26 | 2015-04-28 | Novel Laboratories | Rifaximin crystalline forms and methods of preparation thereof |
EP2927235B1 (en) * | 2014-03-31 | 2017-02-08 | Euticals S.P.A. | Polymorphic mixture of rifaximin and its use for the preparation of solid formulations |
CA2946101A1 (en) * | 2014-04-19 | 2015-10-22 | Granules India Limited | An improved process for the preparation of rifamycin derivatives |
EP3140313B1 (en) | 2014-05-04 | 2020-02-26 | Salix Pharmaceuticals, Inc. | Ibs microbiota and uses thereof |
ES2810010T3 (es) | 2014-05-12 | 2021-03-08 | Alfasigma Spa | Preparación y uso de la forma cristalina tau de rifaximina solvatada con DEGME |
MX2016016458A (es) * | 2014-06-30 | 2017-07-13 | Salix Pharmaceuticals Inc | Métodos para repetir tratamiento de síndrome del intestino irritable (ibs). |
CN104083324B (zh) * | 2014-07-10 | 2017-05-10 | 青岛动保国家工程技术研究中心有限公司 | 一种利福昔明的兽用悬乳剂及其制备方法和应用 |
EP2982764A1 (en) | 2014-08-05 | 2016-02-10 | ALFA WASSERMANN S.p.A. | Identification of vaginal bacteria |
CN104274391B (zh) * | 2014-10-08 | 2017-02-01 | 哈尔滨坤盟医药科技有限公司 | 一种含利福昔明的药物制剂 |
WO2017021975A1 (en) * | 2015-08-06 | 2017-02-09 | Msn Laboratories Private Limited | Process for the preparation of crystalline forms of rifaximin |
EP3294270B1 (en) | 2016-03-24 | 2018-09-12 | Sandoz AG | Pharmaceutical composition containing rifaximin alpha&delta |
HUE044432T2 (hu) | 2016-03-24 | 2019-10-28 | Sandoz Ag | Rifaximin alfá-t tartalmazó, hosszan eltartható kompozíció |
US9988398B2 (en) * | 2016-06-07 | 2018-06-05 | Cadila Healthcare Limited | Crystalline form of rifaximin and process for its preparation |
EP4137132A1 (en) | 2016-09-30 | 2023-02-22 | Salix Pharmaceuticals, Inc. | Solid dispersion forms of rifaximin |
CN106632396B (zh) * | 2017-01-06 | 2019-01-11 | 成都樵枫科技发展有限公司 | γ晶型利福昔明的制备方法和用途 |
PL3416627T3 (pl) * | 2017-04-26 | 2020-06-01 | Sandoz Ag | Doustna postać dawkowania zawierająca rifaksyminę w postaci beta |
EP3645539B1 (en) | 2017-06-26 | 2021-04-07 | Biofer S.p.A. | Pyrido-imidazo rifamycin derivatives as antibacterial agent |
WO2020245214A1 (en) | 2019-06-03 | 2020-12-10 | Bausch Health Ireland Limited | Use of methylnaltrexone and rifaximin for treatment of increased gut permeability or associated disorders |
BR112022003500A2 (pt) | 2019-09-24 | 2022-05-24 | Bausch Health Ireland Ltd | Formulações líquidas de rifaximina |
WO2021191312A1 (en) | 2020-03-24 | 2021-09-30 | Bausch Health Ireland Limited | Methods of treating covid-19 with rifaximin |
WO2021229480A1 (en) * | 2020-05-15 | 2021-11-18 | Atra Pharmaceuticals Limited | Polymorph of rifaximin, process for the preparation thereof and pharmaceutical composition containing rifaximin |
CN116018133A (zh) | 2020-06-26 | 2023-04-25 | 博士医疗爱尔兰有限公司 | 靶向释放利福昔明组合物 |
WO2022090490A1 (en) | 2020-10-29 | 2022-05-05 | Bausch Health Ireland Limited | Rifaximin liquid formulations for use in the treatment of sickle cell disease |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4241785A (en) * | 1978-07-24 | 1980-12-30 | Peerless Of America, Inc. | Heat exchangers and method of making same |
IT1154655B (it) * | 1980-05-22 | 1987-01-21 | Alfa Farmaceutici Spa | Derivati imidazo-rifamicinici metodi per la loro preparazione e loro uso come sostanza ad azione antibatterica |
IT1199374B (it) * | 1984-05-15 | 1988-12-30 | Alfa Farmaceutici Spa | Processo per la preparazione di pirido-imidazo-rifamicine |
CA1215976A (en) | 1984-05-15 | 1986-12-30 | Vincenzo Cannata | New process for the synthesis of imidazo rifamycins |
IT1199413B (it) | 1984-09-26 | 1988-12-30 | Alfa Farmaceutici Spa | Processo per la preparazione di pirido-imidazo-rifamicine |
GB8816620D0 (en) * | 1988-07-13 | 1988-08-17 | Lepetit Spa | Rifapentine hydrohalides |
EP0536197B1 (en) * | 1990-06-29 | 1995-07-26 | GRUPPO LEPETIT S.p.A. | Pure crystalline form of rifapentine |
US20020048610A1 (en) * | 2000-01-07 | 2002-04-25 | Cima Michael J. | High-throughput formation, identification, and analysis of diverse solid-forms |
UA75365C2 (en) * | 2000-08-16 | 2006-04-17 | Bristol Myers Squibb Co | Epothilone analog polymorph modifications, a method for obtaining thereof (variants), a pharmaceutical composition based thereon |
CA2426393C (en) * | 2000-10-31 | 2012-05-29 | Ciba Specialty Chemicals Holding Inc. | Crystalline forms of venlafaxine hydrochloride |
IL156055A0 (en) * | 2000-11-30 | 2003-12-23 | Teva Pharma | Novel crystal forms of atorvastatin hemi calcium and processes for their preparation as well as novel processes for preparing other forms |
ITMI20032144A1 (it) * | 2003-11-07 | 2005-05-08 | Alfa Wassermann Spa | Forme polimorfe di rifaximina, processi per ottenerle e |
US20050262269A1 (en) | 2004-05-20 | 2005-11-24 | Pike Jimmy D | System and method for information handling system PCI express advanced switching |
ES2522895T3 (es) | 2005-03-03 | 2014-11-19 | Alfa Wassermann S.P.A. | Nuevas formas polimorfas de rifaximina, procedimientos para su producción y uso de las mismas en preparados medicinales |
NZ575550A (en) * | 2006-09-22 | 2011-12-22 | Cipla Ltd | Rifaximin |
WO2008115572A1 (en) | 2007-03-21 | 2008-09-25 | Theraquest Biosciences, Inc. | Methods and compositions of nsaids |
ITMI20071241A1 (it) | 2007-06-20 | 2008-12-21 | Solmag S P A | Processo per la preparazione di rifaximina amorfa e rifaximina amorfa cosi' ottenuta |
PL2011486T5 (pl) | 2007-07-06 | 2016-09-30 | Lupin Ltd | Farmaceutyczne kompozycje rifaksyminy |
JP5755878B2 (ja) * | 2007-07-06 | 2015-07-29 | ルパン リミテッドLupin Limited | リファキシミンの薬剤組成物 |
US7709634B2 (en) * | 2007-09-20 | 2010-05-04 | Apotex Pharmachem Inc. | Amorphous form of rifaximin and processes for its preparation |
WO2009047801A1 (en) | 2007-10-10 | 2009-04-16 | Lupin Limited | Therapeutic combinations and compositions for the treatment of gastrointestinal disorders |
MY158257A (en) | 2008-02-25 | 2016-09-30 | Salix Pharmaceuticals Ltd | Forms of rifaximin and uses thereof |
-
2003
- 2003-11-07 IT IT002144A patent/ITMI20032144A1/it unknown
- 2003-12-05 US US10/728,090 patent/US7045620B2/en not_active Expired - Lifetime
-
2004
- 2004-03-09 DE DE602004006367.3T patent/DE602004006367C5/de not_active Expired - Lifetime
- 2004-03-09 IL IL16079804A patent/IL160798A0/xx unknown
- 2004-03-09 DK DK04005541T patent/DK1557421T3/da active
- 2004-03-09 SI SI200431074T patent/SI1676847T1/sl unknown
- 2004-03-09 NZ NZ531622A patent/NZ531622A/en not_active IP Right Cessation
- 2004-03-09 SI SI200431070T patent/SI1676848T1/sl unknown
- 2004-03-09 EP EP06004220A patent/EP1676848B1/en not_active Expired - Lifetime
- 2004-03-09 PT PT06004219T patent/PT1676847E/pt unknown
- 2004-03-09 DE DE602004019296T patent/DE602004019296D1/de not_active Expired - Lifetime
- 2004-03-09 PL PL06004220T patent/PL1676848T3/pl unknown
- 2004-03-09 AT AT06004219T patent/ATE421965T1/de active
- 2004-03-09 DK DK06004219T patent/DK1676847T3/da active
- 2004-03-09 DK DK06004220T patent/DK1676848T3/da active
- 2004-03-09 AT AT06004220T patent/ATE421966T1/de active
- 2004-03-09 SI SI200430297T patent/SI1557421T1/sl unknown
- 2004-03-09 PL PL04005541T patent/PL1557421T3/pl unknown
- 2004-03-09 DE DE602004019298T patent/DE602004019298D1/de not_active Expired - Lifetime
- 2004-03-09 PT PT04005541T patent/PT1557421E/pt unknown
- 2004-03-09 DE DE04005541T patent/DE04005541T1/de active Pending
- 2004-03-09 ES ES06004219T patent/ES2320160T4/es not_active Expired - Lifetime
- 2004-03-09 ES ES04005541T patent/ES2244364T3/es not_active Expired - Lifetime
- 2004-03-09 AT AT04005541T patent/ATE361927T1/de active
- 2004-03-09 EP EP04005541A patent/EP1557421B1/en not_active Expired - Lifetime
- 2004-03-09 EP EP06004219A patent/EP1676847B1/en not_active Expired - Lifetime
- 2004-03-09 PL PL06004219T patent/PL1676847T3/pl unknown
- 2004-03-09 PT PT06004220T patent/PT1676848E/pt unknown
- 2004-03-09 ES ES06004220T patent/ES2320161T3/es not_active Expired - Lifetime
- 2004-03-09 CA CA002460384A patent/CA2460384A1/en not_active Abandoned
- 2004-03-10 AU AU2004200964A patent/AU2004200964A1/en not_active Abandoned
- 2004-03-10 ZA ZA200401948A patent/ZA200401948B/xx unknown
- 2004-03-11 MX MXPA04002353A patent/MXPA04002353A/es unknown
- 2004-03-11 AR ARP040100781A patent/AR043547A1/es not_active Application Discontinuation
- 2004-03-11 CL CL200400498A patent/CL2004000498A1/es unknown
- 2004-03-11 CO CO04022467A patent/CO5560083A1/es not_active Application Discontinuation
- 2004-03-16 CN CNA2004100477623A patent/CN1613858A/zh active Pending
- 2004-03-16 TW TW093106943A patent/TWI285107B/zh not_active IP Right Cessation
- 2004-03-17 JP JP2004076458A patent/JP2005139161A/ja active Pending
- 2004-03-17 KR KR1020040017892A patent/KR20050043589A/ko not_active Application Discontinuation
- 2004-03-18 RU RU2004108953/04A patent/RU2270200C2/ru active
- 2004-03-18 JO JO200433A patent/JO2470B1/en active
- 2004-03-18 HR HRP20040265 patent/HRP20040265A2/hr not_active Application Discontinuation
- 2004-03-19 TN TNP2004000044A patent/TNSN04044A1/en unknown
- 2004-03-19 BR BR0402382-0A patent/BRPI0402382A/pt not_active IP Right Cessation
- 2004-03-19 YU YU24804A patent/YU24804A/sh unknown
- 2004-03-24 MA MA27590A patent/MA27069A1/fr unknown
- 2004-04-11 UA UAA200602354A patent/UA86384C2/uk unknown
- 2004-11-04 CN CN2008100869308A patent/CN101260114B/zh active Active
- 2004-11-04 WO PCT/EP2004/012490 patent/WO2005044823A2/en active Application Filing
- 2004-11-04 MD MDA20060080A patent/MD3653G8/ro active IP Right Grant
- 2004-11-04 EP EP10004590A patent/EP2208730A1/en not_active Withdrawn
- 2004-11-04 RS YUP-2006/0168A patent/RS20060168A/sr unknown
- 2004-11-04 EP EP04797615A patent/EP1682556A2/en not_active Withdrawn
- 2004-11-04 RS RS20060168A patent/RS54568B1/en unknown
- 2004-11-04 KR KR1020077026410A patent/KR100867751B1/ko active IP Right Grant
- 2004-11-04 CA CA2538546A patent/CA2538546C/en active Active
- 2004-11-04 BR BRPI0407149A patent/BRPI0407149A8/pt not_active Application Discontinuation
- 2004-11-04 KR KR1020077026409A patent/KR100883216B1/ko active IP Right Grant
- 2004-11-04 RS RS20150292A patent/RS54571B1/en unknown
- 2004-11-04 EP EP10004589A patent/EP2210893A1/en not_active Withdrawn
- 2004-11-04 CN CN2004800030228A patent/CN1886408B/zh active Active
- 2004-11-04 KR KR1020057013910A patent/KR100855084B1/ko active IP Right Review Request
- 2004-11-04 MX MXPA06002644A patent/MXPA06002644A/es active IP Right Grant
- 2004-11-04 JP JP2006537252A patent/JP5199576B2/ja active Active
- 2004-11-04 CN CN2008100869327A patent/CN101260115B/zh active Active
- 2004-11-04 RS RS20150291A patent/RS54569B1/en unknown
- 2004-11-04 ME MEP-2008-633A patent/ME00424B/me unknown
- 2004-11-04 AU AU2004287601A patent/AU2004287601B8/en active Active
-
2005
- 2005-05-24 US US11/135,651 patent/US20050272754A1/en not_active Abandoned
- 2005-08-04 HK HK06113864.0A patent/HK1092151A1/xx not_active IP Right Cessation
- 2005-08-04 HK HK06113863.1A patent/HK1092150A1/xx not_active IP Right Cessation
- 2005-08-04 HK HK05106702A patent/HK1073657A1/xx not_active IP Right Cessation
-
2006
- 2006-03-01 TN TNP2006000069A patent/TNSN06069A1/en unknown
- 2006-03-08 HR HRP20060093AA patent/HRP20060093B1/hr active IP Right Grant
- 2006-03-08 NO NO20061110A patent/NO334950B1/no unknown
- 2006-03-12 IL IL174271A patent/IL174271A/en active IP Right Grant
-
2007
- 2007-07-02 CY CY20071100875T patent/CY1108017T1/el unknown
- 2007-10-17 US US11/873,841 patent/US7915275B2/en active Active
-
2009
- 2009-03-23 CY CY20091100319T patent/CY1108909T1/el unknown
- 2009-04-09 CY CY20091100414T patent/CY1108964T1/el unknown
-
2010
- 2010-11-19 JP JP2010259452A patent/JP2011057698A/ja not_active Withdrawn
- 2010-11-19 JP JP2010259453A patent/JP5635376B2/ja active Active
-
2011
- 2011-03-04 US US13/041,348 patent/US8404704B2/en active Active
- 2011-03-04 US US13/041,346 patent/US8173801B2/en active Active
- 2011-06-23 AR ARP110102194A patent/AR081992A2/es not_active Application Discontinuation
- 2011-06-23 AR ARP110102193A patent/AR081991A2/es not_active Application Discontinuation
-
2014
- 2014-07-04 JP JP2014138697A patent/JP2014177500A/ja active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
YU24804A (sh) | Polimorfni oblici rifaksimina, postupci za njegovu proizvodnju i njegova upotreba u medicinskim preparatima | |
NO20074988L (no) | Nye polymorfe former av rifaximin, prosesser for deres fremstilling og anvendelse derav i medisin | |
DE69940525D1 (de) | Zubereitung, die einen zellextrakt zur herstellung eines zellfreien proteins enthalten und vorrichtung zur herstellung eines zellfreien proteins | |
WO2006024389A3 (de) | Biphenylthiazolcarboxamide | |
ZA200402858B (en) | Novel beta-phenyl-alpha-oxysubstituted propionic derivatives; process for its preparation and their use in the preparation of pharmaceutically important compounds. | |
IL174919A0 (en) | Diamine derivatives, process for the production thereof and plant disease control compositions containing the same | |
MXPA03012013A (es) | Derivados de 1-oxa-2,8-diaza-spiro[4,5]dec-2-eno sustituidos como medicamento para el tratamiento de dolor. | |
AU2003298218A1 (en) | Composition for controlled tempering by means of phase change, production and use thereof | |
AP2153A (en) | Process for the production of invert liquid sugar. | |
WO2004087700A8 (fr) | Derives du benzenesulfonamide, leur procede de preparation et leur utilisation de la douleur | |
MY126071A (en) | Crystalline form ii of cabergoline. | |
AU2003266216A1 (en) | Purification process comprising microfiltration at elevated temperatures | |
TW200613565A (en) | Collagen of fish scale and its manufacturing method | |
EP1405857A4 (en) | PROCESS FOR THE PRODUCTION OF OXAZOLINE-SACCHARIDE DERIVATIVES | |
GB0304716D0 (en) | Method for producing partially frozen ice-water-air mixtures | |
MD3101G2 (ro) | Procedeu de obţinere a biomasei de Spirulina platensis | |
NO20072245L (no) | Anvendelse av IL-17 til modning av oocytter | |
NO912685L (no) | Nye radikale litiumftalocyaninkrystaller, deres fremstillingsprosess og deres bruk til in vivo bestemmelse av molekylaert oksygen. | |
MY144578A (en) | New polymorphous forms of rifaximin, processes for their production and use thereof in the medicinal preparations | |
PT1711479E (pt) | Processo para a produção de bis-anidrido de dtpa | |
NO20033126L (no) | Metabolsk kontrollert fermenteringsprosess for karbamoyltobramycinproduksjon | |
FR2837833B1 (fr) | Procede de culture en masse, de la diatomee "haslea ostrearia simonsen" et utilisation des cultures obtenues par le procede | |
AU2003283574A1 (en) | Process for the purification of hydroxyaryl-aldhydes and ketones and their use in the production of hydroxyaryl oxime derivatives | |
HUP0303692A2 (hu) | Mézeskalácsdísz, eljárás az előállítására és alkalmazása | |
WO2004050044A3 (de) | Verwendung von emulgatorengemischen zur herstellung kosmetischer mittel |