BR9906600A - Forma de dosagem oral sólida compreendendo uma combinação de metformina e glibenclamida - Google Patents

Forma de dosagem oral sólida compreendendo uma combinação de metformina e glibenclamida

Info

Publication number
BR9906600A
BR9906600A BR9906600-9A BR9906600A BR9906600A BR 9906600 A BR9906600 A BR 9906600A BR 9906600 A BR9906600 A BR 9906600A BR 9906600 A BR9906600 A BR 9906600A
Authority
BR
Brazil
Prior art keywords
metformin
combination
dosage form
oral dosage
solid oral
Prior art date
Application number
BR9906600-9A
Other languages
English (en)
Inventor
Yves Bonhomme
Geoffrey Nicholson
Gillian Cave
Sarah J Nicholson
Original Assignee
Lipha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8235441&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9906600(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lipha filed Critical Lipha
Publication of BR9906600A publication Critical patent/BR9906600A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

Abstract

Patente de Invenção: <B>"FORMA DE DOSAGEM ORAL SóLIDA COMPREENDENDO UMA COMBINAçãO DE METFORMINA E GLIBENCLAMIDA"<D>. A presente invenção refere-se a uma forma de dosagem oral sólida compreendendo uma combinação de metformina e glibenclamida onde o tamanho de glibenclamida é tal que a biodisponibilidade de glibenclamida é comparável à biodisponibilidade de glibenclamida obtida com uma administração separada de metformida e glibenclamida.
BR9906600-9A 1998-07-15 1999-07-12 Forma de dosagem oral sólida compreendendo uma combinação de metformina e glibenclamida BR9906600A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98401781A EP0974356B1 (en) 1998-07-15 1998-07-15 Tablets comprising a combination of metformin and glibenclamide
PCT/EP1999/005571 WO2000003742A2 (en) 1998-07-15 1999-07-12 Solid oral dosage form comprising a combination of metformin and glibenclamide

Publications (1)

Publication Number Publication Date
BR9906600A true BR9906600A (pt) 2000-07-18

Family

ID=8235441

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9906600-9A BR9906600A (pt) 1998-07-15 1999-07-12 Forma de dosagem oral sólida compreendendo uma combinação de metformina e glibenclamida

Country Status (27)

Country Link
US (2) US6303146B1 (pt)
EP (4) EP0974356B1 (pt)
JP (2) JP2002520371A (pt)
KR (2) KR20040053177A (pt)
CN (2) CN1486698A (pt)
AP (1) AP1450A (pt)
AR (2) AR013052A1 (pt)
AT (1) ATE250418T1 (pt)
AU (2) AU753604B2 (pt)
BR (1) BR9906600A (pt)
CA (1) CA2303537C (pt)
DE (1) DE69818444T2 (pt)
DK (1) DK0974356T3 (pt)
DZ (1) DZ2846A1 (pt)
ES (1) ES2206868T3 (pt)
ID (1) ID25784A (pt)
MA (1) MA24930A1 (pt)
MY (1) MY129552A (pt)
NZ (1) NZ503248A (pt)
OA (1) OA11400A (pt)
PT (1) PT974356E (pt)
RU (2) RU2226396C2 (pt)
SI (1) SI0974356T1 (pt)
TW (2) TWI245632B (pt)
UY (1) UY25611A1 (pt)
WO (1) WO2000003742A2 (pt)
ZA (1) ZA200001159B (pt)

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FR2816841B1 (fr) * 2000-11-22 2004-02-06 Lipha Nouvelles compositions pharmaceutiques a action antidiabetique et leur procede de preparation
CA2434169C (en) * 2001-01-12 2011-03-15 Sun Pharmaceutical Industries Limited Spaced drug delivery system
FR2825023B1 (fr) * 2001-05-23 2005-04-15 Flamel Tech Sa Forme pharmaceutique orale antidiabetique "une prise par jour"comprenant une biguanide et au moins un autre principe actif
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US7767249B2 (en) * 2001-06-07 2010-08-03 Hewlett-Packard Development Company, L.P. Preparation of nanoparticles
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US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
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US7183321B2 (en) * 2001-12-17 2007-02-27 Bristol-Myers Squibb Company Antidiabetic formulation and method
ES2284829T3 (es) * 2002-01-25 2007-11-16 Laboratorios Silanes, S.A. De C.V. Composicion farmaceutica que se usa para controlar la glucosa en sangre en pacientes con diabetes de tipo 2.
ES2627842T3 (es) * 2002-02-21 2017-07-31 Valeant Pharmaceuticals Luxembourg S.À.R.L. Formas de dosificación de liberación controlada
US20030187074A1 (en) * 2002-03-04 2003-10-02 Javed Hussain Oral compositions for treatment of diabetes
US20030219482A1 (en) * 2002-03-21 2003-11-27 Chaudhari Sunil Sudhakar Multiparticulate compositions for once-a-day administration
IL164221A0 (en) 2002-04-09 2005-12-18 Flamel Tech Sa Oral pharmaceutical formulation in the form of aqueous suspension of microcapsules for modified release of amoxicillim
MXPA04009968A (es) 2002-04-09 2004-12-13 Flamel Tech Sa Formulacion farmaceutica oral bajo forma de suspension acuosa de microcapsulas que permiten la liberacion modificada de principio (s) activo (s).
KR100897890B1 (ko) 2002-06-17 2009-05-18 인벤티아 헬스케어 피브이티. 엘티디. 티아졸리딘디온 및 바이구아나이드를 함유하는 다층 정제및 그의 제조 방법
US7445796B2 (en) * 2002-08-19 2008-11-04 L. Perrigo Company Pharmaceutically active particles of a monomodal particle size distribution and method
EP1562607A1 (en) * 2002-11-15 2005-08-17 Ranbaxy Laboratories, Ltd. Pharmaceutical dosage forms of biguanide-sulfonylurea combinations
FR2853831A1 (fr) * 2003-03-05 2004-10-22 Usv Ltd Forme posologique solide a usage oral de metformine et de glyburide et son procede de preparation
JPWO2004091661A1 (ja) * 2003-04-15 2006-07-06 中外製薬株式会社 糖尿病治療剤
US20060121108A1 (en) * 2004-12-02 2006-06-08 Prasad C K System and method for producing a directly compressible, high-potency formulation of metformin hydrochloride
CN100341495C (zh) * 2004-12-29 2007-10-10 三九医药股份有限公司 格列本脲固体分散体、口服组合物及其制备方法
KR100760430B1 (ko) * 2004-12-31 2007-10-04 한미약품 주식회사 당뇨병 치료제의 경구 투여용 서방성 복합 제제 및 이의제조 방법
PE20061245A1 (es) * 2005-03-30 2007-01-06 Generex Pharm Inc Composiciones para la transmision transmucosa oral de la metformina
US8529537B2 (en) * 2005-08-05 2013-09-10 Kimberly-Clark Worldwide, Inc. Absorbent article with enclosures
MXPA05009633A (es) * 2005-09-08 2007-03-07 Silanes Sa De Cv Lab Composicion farmaceutica estable de glimepirida de liberacion inmediata y metformina de liberacion prolongada.
WO2008002591A2 (en) 2006-06-26 2008-01-03 Amgen Inc Methods for treating atherosclerosis
WO2008062273A2 (en) * 2006-11-20 2008-05-29 Cadila Pharmaceuticals Limited Solid oral dosage form having antidiabetic drug combination
JO3272B1 (ar) 2007-07-19 2018-09-16 Takeda Pharmaceuticals Co مستحضر صلب يشمل ألوجليبتين وميتفورمين هيدروكلوريد
EA201070187A1 (ru) 2007-07-26 2010-08-30 Эмджен Инк. Модифицированные ферменты лецитин-холестерин ацилтрансферазы
US20110009347A1 (en) 2009-07-08 2011-01-13 Yin Liang Combination therapy for the treatment of diabetes
US20130108699A1 (en) * 2010-04-26 2013-05-02 Jose Antonio Matji Tuduri Highly dispersible granulate for the preparation of formulations of high dosage active substances and procedure for obtaining high dosage active substances thereof
RU2451506C1 (ru) 2011-06-02 2012-05-27 Сергей Юрьевич Лешков Комбинация для лечения сахарного диабета и его осложнений
CN104220460A (zh) 2011-12-08 2014-12-17 安姆根有限公司 激动人lcat抗原结合蛋白和它们在疗法中的用途
CN104127424A (zh) * 2014-07-30 2014-11-05 沈阳药科大学 格列本脲衍生物及其制备方法和应用
CN105030793A (zh) * 2015-08-25 2015-11-11 瑞阳制药有限公司 二甲双胍格列本脲胶囊及其制备方法
WO2019070109A1 (es) * 2017-10-03 2019-04-11 Infinite Clinical Research International, S.A. De C.V. Triconjugado para el tratamiento de diabetes mellitus
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CN113143940A (zh) * 2020-12-30 2021-07-23 成都恒瑞制药有限公司 一种抗糖尿病药物组合物的制备方法

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Also Published As

Publication number Publication date
JP2003292443A (ja) 2003-10-15
CN1486698A (zh) 2004-04-07
ID25784A (id) 2000-11-02
AP2000001757A0 (en) 2000-03-31
NZ503248A (en) 2002-09-27
EP1435240A2 (en) 2004-07-07
CN1146427C (zh) 2004-04-21
EP1011684A2 (en) 2000-06-28
EP1435240A3 (en) 2009-08-12
CA2303537C (en) 2005-12-06
TW200303208A (en) 2003-09-01
JP2002520371A (ja) 2002-07-09
KR100478347B1 (ko) 2005-03-23
CN1275082A (zh) 2000-11-29
DE69818444D1 (de) 2003-10-30
UY25611A1 (es) 2000-08-21
USRE38629E1 (en) 2004-10-19
DZ2846A1 (fr) 2003-12-01
PT974356E (pt) 2004-02-27
KR20010030603A (ko) 2001-04-16
MA24930A1 (fr) 2000-04-01
RU2286788C2 (ru) 2006-11-10
MY129552A (en) 2007-04-30
EP0974356B1 (en) 2003-09-24
TWI245632B (en) 2005-12-21
EP2269613A2 (en) 2011-01-05
EP0974356A1 (en) 2000-01-26
CA2303537A1 (en) 2000-01-27
AR013052A1 (es) 2000-11-22
DE69818444T2 (de) 2004-05-06
AP1450A (en) 2005-07-25
US6303146B1 (en) 2001-10-16
AU5417999A (en) 2000-02-07
EP2269613A3 (en) 2012-10-17
AR065970A2 (es) 2009-07-15
AU2003261560A1 (en) 2005-05-26
KR20040053177A (ko) 2004-06-23
TW555560B (en) 2003-10-01
RU2226396C2 (ru) 2004-04-10
SI0974356T1 (en) 2003-12-31
OA11400A (en) 2004-04-08
RU2003126257A (ru) 2005-02-27
ATE250418T1 (de) 2003-10-15
ZA200001159B (en) 2001-05-31
AU753604B2 (en) 2002-10-24
WO2000003742A2 (en) 2000-01-27
ES2206868T3 (es) 2004-05-16
DK0974356T3 (da) 2003-10-27
WO2000003742A3 (en) 2000-04-20

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFERIMENTO DO PRESENTE PEDIDO, UMA VEZ QUE O MESMO NAO ATENDE AOS ESTABELECIDO NOS ARTIGOS 8O E 13, E 25 DA LPI - LEI 9279/96

B12B Appeal against refusal [chapter 12.2 patent gazette]
B15G Petition not considered as such [chapter 15.7 patent gazette]

Free format text: DESCONHECIDA DA PETICAO NO 020110110801/RJ DE 27/10/2011, O PEDIDO DE ALTERACAO DE NOME E SEDE POR AUSENCIA DE FUNDAMENTACAO LEGAL, UMA VEZ QUE O PEDIDO FOI INDEFERIDO CONFORME PUBLICADO NA RPI 2040 DE 09/02/2010.

B25H Request for change of headquarter rejected

Owner name: LIPHA (FR)

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08H Application fees: decision cancelled [chapter 8.8 patent gazette]