DK0974356T3 - Tabletter omfattende en kombination af metformin og glibenclamid - Google Patents

Tabletter omfattende en kombination af metformin og glibenclamid

Info

Publication number
DK0974356T3
DK0974356T3 DK98401781T DK98401781T DK0974356T3 DK 0974356 T3 DK0974356 T3 DK 0974356T3 DK 98401781 T DK98401781 T DK 98401781T DK 98401781 T DK98401781 T DK 98401781T DK 0974356 T3 DK0974356 T3 DK 0974356T3
Authority
DK
Denmark
Prior art keywords
glibenclamide
metformin
tablets
combination
Prior art date
Application number
DK98401781T
Other languages
Danish (da)
English (en)
Inventor
Yves Bonhomme
Geoffrey Nicholson
Original Assignee
Merck Sante Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8235441&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0974356(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck Sante Sas filed Critical Merck Sante Sas
Application granted granted Critical
Publication of DK0974356T3 publication Critical patent/DK0974356T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK98401781T 1998-07-15 1998-07-15 Tabletter omfattende en kombination af metformin og glibenclamid DK0974356T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98401781A EP0974356B1 (en) 1998-07-15 1998-07-15 Tablets comprising a combination of metformin and glibenclamide

Publications (1)

Publication Number Publication Date
DK0974356T3 true DK0974356T3 (da) 2003-10-27

Family

ID=8235441

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98401781T DK0974356T3 (da) 1998-07-15 1998-07-15 Tabletter omfattende en kombination af metformin og glibenclamid

Country Status (27)

Country Link
US (2) US6303146B1 (pt)
EP (4) EP0974356B1 (pt)
JP (2) JP2002520371A (pt)
KR (2) KR20040053177A (pt)
CN (2) CN1486698A (pt)
AP (1) AP1450A (pt)
AR (2) AR013052A1 (pt)
AT (1) ATE250418T1 (pt)
AU (2) AU753604B2 (pt)
BR (1) BR9906600A (pt)
CA (1) CA2303537C (pt)
DE (1) DE69818444T2 (pt)
DK (1) DK0974356T3 (pt)
DZ (1) DZ2846A1 (pt)
ES (1) ES2206868T3 (pt)
ID (1) ID25784A (pt)
MA (1) MA24930A1 (pt)
MY (1) MY129552A (pt)
NZ (1) NZ503248A (pt)
OA (1) OA11400A (pt)
PT (1) PT974356E (pt)
RU (2) RU2286788C2 (pt)
SI (1) SI0974356T1 (pt)
TW (2) TW555560B (pt)
UY (1) UY25611A1 (pt)
WO (1) WO2000003742A2 (pt)
ZA (1) ZA200001159B (pt)

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FR2816841B1 (fr) * 2000-11-22 2004-02-06 Lipha Nouvelles compositions pharmaceutiques a action antidiabetique et leur procede de preparation
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FR2825023B1 (fr) * 2001-05-23 2005-04-15 Flamel Tech Sa Forme pharmaceutique orale antidiabetique "une prise par jour"comprenant une biguanide et au moins un autre principe actif
US7767249B2 (en) * 2001-06-07 2010-08-03 Hewlett-Packard Development Company, L.P. Preparation of nanoparticles
US20050271737A1 (en) * 2001-06-07 2005-12-08 Chinea Vanessa I Application of a bioactive agent to a substrate
US8206753B2 (en) * 2001-06-20 2012-06-26 Metaproteomics, Llc Anti-inflammatory botanical products for the treatment of metabolic syndrome and diabetes
CA2454732C (en) 2001-07-30 2010-07-20 Mitsubishi Pharma Corporation Drugs for ameliorating postcibal hyperglycemia
US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
ITFI20010230A1 (it) * 2001-11-29 2003-05-29 Menarini Int Operations Lu Sa Composizioni farmaceutiche per il trattamento del diabete mellito di tipo ii
US7183321B2 (en) * 2001-12-17 2007-02-27 Bristol-Myers Squibb Company Antidiabetic formulation and method
WO2003061643A1 (es) * 2002-01-25 2003-07-31 Laboratorios Silanes, S.A. De C.V. Composicion farmaceutica para el control de la glucosa en sangre de pacientes con diabetes tipo 2
EP1476139B1 (en) * 2002-02-21 2017-05-17 Valeant Pharmaceuticals Luxembourg S.à.r.l. Controlled release dosage forms
US20030187074A1 (en) * 2002-03-04 2003-10-02 Javed Hussain Oral compositions for treatment of diabetes
US20030219482A1 (en) * 2002-03-21 2003-11-27 Chaudhari Sunil Sudhakar Multiparticulate compositions for once-a-day administration
DE60325709D1 (de) 2002-04-09 2009-02-26 Flamel Tech Sa Orale wässrige suspension, mikrokapseln enthaltend, zur kontrollierten freisetzung von wirkstoffen
CA2480824A1 (fr) 2002-04-09 2003-10-16 Flamel Technologies Formulation pharmaceutique orale sous forme de suspension aqueuse de microcapsules permettant la liberation modifiee d'amoxicilline
KR100897890B1 (ko) 2002-06-17 2009-05-18 인벤티아 헬스케어 피브이티. 엘티디. 티아졸리딘디온 및 바이구아나이드를 함유하는 다층 정제및 그의 제조 방법
US7445796B2 (en) * 2002-08-19 2008-11-04 L. Perrigo Company Pharmaceutically active particles of a monomodal particle size distribution and method
CN1729005A (zh) * 2002-11-15 2006-02-01 兰贝克赛实验室有限公司 含双胍－磺酰脲类组合的药物剂型
FR2853831A1 (fr) * 2003-03-05 2004-10-22 Usv Ltd Forme posologique solide a usage oral de metformine et de glyburide et son procede de preparation
WO2004091661A1 (ja) * 2003-04-15 2004-10-28 Chugai Seiyaku Kabushiki Kaisha 糖尿病治療剤
US20060121108A1 (en) * 2004-12-02 2006-06-08 Prasad C K System and method for producing a directly compressible, high-potency formulation of metformin hydrochloride
CN100341495C (zh) * 2004-12-29 2007-10-10 三九医药股份有限公司 格列本脲固体分散体、口服组合物及其制备方法
KR100760430B1 (ko) * 2004-12-31 2007-10-04 한미약품 주식회사 당뇨병 치료제의 경구 투여용 서방성 복합 제제 및 이의제조 방법
PE20061245A1 (es) * 2005-03-30 2007-01-06 Generex Pharm Inc Composiciones para la transmision transmucosa oral de la metformina
US8529537B2 (en) * 2005-08-05 2013-09-10 Kimberly-Clark Worldwide, Inc. Absorbent article with enclosures
MXPA05009633A (es) * 2005-09-08 2007-03-07 Silanes Sa De Cv Lab Composicion farmaceutica estable de glimepirida de liberacion inmediata y metformina de liberacion prolongada.
ATE540681T1 (de) 2006-06-26 2012-01-15 Amgen Inc Verfahren zur behandlung von atherosklerose
WO2008062273A2 (en) * 2006-11-20 2008-05-29 Cadila Pharmaceuticals Limited Solid oral dosage form having antidiabetic drug combination
GEP20125672B (en) 2007-07-19 2012-10-25 Takeda Pharmaceuticals Co ) solid composition containing alogliptin and metformin hydrochloride
JP5643643B2 (ja) 2007-07-26 2014-12-17 アムジエン・インコーポレーテツド 変性レシチン−コレステロールアシルトランスフェラーゼ酵素
US20110009347A1 (en) 2009-07-08 2011-01-13 Yin Liang Combination therapy for the treatment of diabetes
WO2011135106A1 (es) * 2010-04-26 2011-11-03 Smart Pharma Solutions, S.L Granulado altamente dispersable para la preparación de formulaciones de sustancias activas de altas dosis y procedimiento de obtención del mismo
RU2451506C1 (ru) 2011-06-02 2012-05-27 Сергей Юрьевич Лешков Комбинация для лечения сахарного диабета и его осложнений
CN104220460A (zh) 2011-12-08 2014-12-17 安姆根有限公司 激动人lcat抗原结合蛋白和它们在疗法中的用途
CN104127424A (zh) * 2014-07-30 2014-11-05 沈阳药科大学 格列本脲衍生物及其制备方法和应用
CN105030793A (zh) * 2015-08-25 2015-11-11 瑞阳制药有限公司 二甲双胍格列本脲胶囊及其制备方法
WO2019070109A1 (es) * 2017-10-03 2019-04-11 Infinite Clinical Research International, S.A. De C.V. Triconjugado para el tratamiento de diabetes mellitus
KR102484756B1 (ko) * 2020-11-13 2023-01-06 한국생산기술연구원 용해성 증대 및 취급용이성을 갖는 파우더 배지의 과립화 방법
CN113143940A (zh) * 2020-12-30 2021-07-23 成都恒瑞制药有限公司 一种抗糖尿病药物组合物的制备方法

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DE362704C (de) * 1921-08-09 1922-11-02 Naamlooze Vennootschap Interna Vorrichtung zum Senken einer Last, insbesondere eines Rettungsbootes
US3174901A (en) 1963-01-31 1965-03-23 Jan Marcel Didier Aron Samuel Process for the oral treatment of diabetes
DE2348334C2 (de) 1973-09-26 1982-11-11 Boehringer Mannheim Gmbh, 6800 Mannheim Neue Zubereitungsform des N-4-[2-(5-Chlor-2-methoxybenzamido)äthyl]- phenyl-sulfonyl-N'-cyclohexylharnstoffs
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DE4323636A1 (de) 1993-07-15 1995-01-19 Hoechst Ag Arzneistoffzubereitungen aus umhüllten, schwerstwasserlöslichen Arzneistoffen für Inhalationsarzneiformen und Verfahren zu ihrer Herstellung
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ATE355840T1 (de) 1997-06-18 2007-03-15 Smithkline Beecham Plc Behandlung der diabetes mit thiazolidindione und metformin
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Also Published As

Publication number Publication date
AU753604B2 (en) 2002-10-24
TW555560B (en) 2003-10-01
TWI245632B (en) 2005-12-21
MY129552A (en) 2007-04-30
JP2002520371A (ja) 2002-07-09
CN1275082A (zh) 2000-11-29
RU2003126257A (ru) 2005-02-27
AU5417999A (en) 2000-02-07
EP1435240A3 (en) 2009-08-12
TW200303208A (en) 2003-09-01
EP0974356A1 (en) 2000-01-26
MA24930A1 (fr) 2000-04-01
DZ2846A1 (fr) 2003-12-01
ID25784A (id) 2000-11-02
USRE38629E1 (en) 2004-10-19
ZA200001159B (en) 2001-05-31
DE69818444D1 (de) 2003-10-30
ES2206868T3 (es) 2004-05-16
EP0974356B1 (en) 2003-09-24
EP1011684A2 (en) 2000-06-28
OA11400A (en) 2004-04-08
KR20040053177A (ko) 2004-06-23
UY25611A1 (es) 2000-08-21
NZ503248A (en) 2002-09-27
AU2003261560A1 (en) 2005-05-26
DE69818444T2 (de) 2004-05-06
KR100478347B1 (ko) 2005-03-23
JP2003292443A (ja) 2003-10-15
AR065970A2 (es) 2009-07-15
WO2000003742A2 (en) 2000-01-27
AP1450A (en) 2005-07-25
EP2269613A3 (en) 2012-10-17
CA2303537C (en) 2005-12-06
PT974356E (pt) 2004-02-27
RU2286788C2 (ru) 2006-11-10
EP1435240A2 (en) 2004-07-07
BR9906600A (pt) 2000-07-18
CN1146427C (zh) 2004-04-21
EP2269613A2 (en) 2011-01-05
CA2303537A1 (en) 2000-01-27
ATE250418T1 (de) 2003-10-15
RU2226396C2 (ru) 2004-04-10
AR013052A1 (es) 2000-11-22
SI0974356T1 (en) 2003-12-31
WO2000003742A3 (en) 2000-04-20
KR20010030603A (ko) 2001-04-16
AP2000001757A0 (en) 2000-03-31
CN1486698A (zh) 2004-04-07
US6303146B1 (en) 2001-10-16

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