HUP0302276A2 - Bikalutamidot és tamoxifent tartalmazó gyógyszerkombináció anti-androgén és anti-ösztrogén hatás előidézésére - Google Patents

Bikalutamidot és tamoxifent tartalmazó gyógyszerkombináció anti-androgén és anti-ösztrogén hatás előidézésére

Info

Publication number
HUP0302276A2
HUP0302276A2 HU0302276A HUP0302276A HUP0302276A2 HU P0302276 A2 HUP0302276 A2 HU P0302276A2 HU 0302276 A HU0302276 A HU 0302276A HU P0302276 A HUP0302276 A HU P0302276A HU P0302276 A2 HUP0302276 A2 HU P0302276A2
Authority
HU
Hungary
Prior art keywords
effect
tamoxifen
bicalutamide
providing
pharmaceutical combination
Prior art date
Application number
HU0302276A
Other languages
English (en)
Inventor
Barrington Furr
Original Assignee
Astrazeneca Ab,
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab, filed Critical Astrazeneca Ab,
Publication of HUP0302276A2 publication Critical patent/HUP0302276A2/hu
Publication of HUP0302276A3 publication Critical patent/HUP0302276A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Diabetes (AREA)
  • Pregnancy & Childbirth (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A találmány tárgya betegeknek antiandrogén és antiösztrogén hatáselőidézésére beadandó gyógyászati készítmény, amely (I) képletűvegyületet vagy annak gyógyászatilag alkalmazható sóját vagyszolvátját és tamoxifent vagy annak gyógyászatilag alkalmazható sójátvagy szolvátját tartalmazza (25-350) : (0,5-100) (I) képletű vegyület: tamoxifen aránynak megfelelő mennyiségben. Ó
HU0302276A 2000-05-23 2001-05-22 Pharmaceutical combination of bicalutamide and tamoxifen for providing an anti-androgenic effect and an anti-oestrogenic effect HUP0302276A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0012291.1A GB0012291D0 (en) 2000-05-23 2000-05-23 Pharmaceutical combination
PCT/SE2001/001162 WO2001089515A1 (en) 2000-05-23 2001-05-22 Pharmaceutical combination of bicalutamide and tamoxifen for providing an anti-androgenic effect and an anti-oestrogenic effect

Publications (2)

Publication Number Publication Date
HUP0302276A2 true HUP0302276A2 (hu) 2003-11-28
HUP0302276A3 HUP0302276A3 (en) 2005-06-28

Family

ID=9892038

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0302276A HUP0302276A3 (en) 2000-05-23 2001-05-22 Pharmaceutical combination of bicalutamide and tamoxifen for providing an anti-androgenic effect and an anti-oestrogenic effect

Country Status (23)

Country Link
US (1) US20030134899A1 (hu)
EP (1) EP1292296A1 (hu)
JP (1) JP2003534278A (hu)
KR (1) KR20030001535A (hu)
CN (1) CN1431899A (hu)
AU (1) AU2001262833A1 (hu)
BR (1) BR0111051A (hu)
CA (1) CA2407028A1 (hu)
CZ (1) CZ20023785A3 (hu)
EE (1) EE200200654A (hu)
GB (1) GB0012291D0 (hu)
HK (1) HK1053061A1 (hu)
HU (1) HUP0302276A3 (hu)
IL (1) IL152545A0 (hu)
IS (1) IS6589A (hu)
MX (1) MXPA02011472A (hu)
NO (1) NO20025638L (hu)
NZ (1) NZ521979A (hu)
PL (1) PL363504A1 (hu)
RU (1) RU2002134483A (hu)
SK (1) SK16562002A3 (hu)
WO (1) WO2001089515A1 (hu)
ZA (1) ZA200208845B (hu)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0103838D0 (sv) * 2001-11-16 2001-11-16 Astrazeneca Ab Pharmaceutical formulation & product
US20040214898A1 (en) * 2001-11-29 2004-10-28 Steiner Mitchell S. Methods for treating hot flashes
US20080249183A1 (en) * 2001-11-29 2008-10-09 Steiner Mitchell S Treatment of androgen-deprivation induced osteoporosis
US20050080143A1 (en) * 2001-11-29 2005-04-14 Steiner Mitchell S. Treatment of androgen-deprivation induced osteoporosis
US20060269611A1 (en) * 2001-11-29 2006-11-30 Steiner Mitchell S Prevention and treatment of androgen-deprivation induced osteoporosis
US20070197664A1 (en) * 2001-11-29 2007-08-23 Steiner Mitchell S Prevention and treatment of androgen-deprivation induced osteoporosis
US7524866B2 (en) 2001-11-29 2009-04-28 Gtx, Inc. Prevention and treatment of androgen—deprivation induced osteoporosis
ES2319785T3 (es) * 2001-11-29 2009-05-12 Gtx, Inc. Prevencion y tratamiento de osteoporosis inducida por privacion de androgenos.
US7332525B2 (en) * 2003-01-17 2008-02-19 Castle Erik P Method of treatment of prostate cancer and composition for treatment thereof
GB0424339D0 (en) * 2004-11-03 2004-12-08 Astrazeneca Ab Combination therapy
US20080177109A1 (en) * 2005-03-29 2008-07-24 Usv Limited Novel Process for Preparation of Bicalutamide
CN114748480B (zh) * 2021-01-08 2023-10-20 轩竹生物科技股份有限公司 一种预防和/或治疗癌症的药物组合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE637389A (hu) * 1962-09-13
ATE28864T1 (de) * 1982-07-23 1987-08-15 Ici Plc Amide-derivate.
US4895715A (en) * 1988-04-14 1990-01-23 Schering Corporation Method of treating gynecomastia
EP0748220A4 (en) * 1994-01-21 1997-09-10 Sepracor Inc METHOD AND COMPOSITIONS FOR TREATING ANDROGEN-DEPENDENT DISEASES USING OPTICALLY PURE R - (-) CASODEX

Also Published As

Publication number Publication date
NO20025638D0 (no) 2002-11-22
CN1431899A (zh) 2003-07-23
CA2407028A1 (en) 2001-11-29
RU2002134483A (ru) 2004-06-27
MXPA02011472A (es) 2004-09-06
IL152545A0 (en) 2003-05-29
EP1292296A1 (en) 2003-03-19
EE200200654A (et) 2004-06-15
GB0012291D0 (en) 2000-07-12
AU2001262833A1 (en) 2001-12-03
PL363504A1 (en) 2004-11-29
BR0111051A (pt) 2003-04-15
HK1053061A1 (zh) 2003-10-10
US20030134899A1 (en) 2003-07-17
WO2001089515A1 (en) 2001-11-29
ZA200208845B (en) 2004-02-27
JP2003534278A (ja) 2003-11-18
NZ521979A (en) 2004-06-25
SK16562002A3 (sk) 2003-05-02
NO20025638L (no) 2002-11-22
IS6589A (is) 2002-10-25
HUP0302276A3 (en) 2005-06-28
CZ20023785A3 (cs) 2003-03-12
KR20030001535A (ko) 2003-01-06

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