HUP0302571A2 - Szerves vegyületek keverékét tartalmazó gyógyszerkészítmény légúti betegségek kezelésére - Google Patents
Szerves vegyületek keverékét tartalmazó gyógyszerkészítmény légúti betegségek kezeléséreInfo
- Publication number
- HUP0302571A2 HUP0302571A2 HU0302571A HUP0302571A HUP0302571A2 HU P0302571 A2 HUP0302571 A2 HU P0302571A2 HU 0302571 A HU0302571 A HU 0302571A HU P0302571 A HUP0302571 A HU P0302571A HU P0302571 A2 HUP0302571 A2 HU P0302571A2
- Authority
- HU
- Hungary
- Prior art keywords
- treatment
- pharmaceutical composition
- composition containing
- organic compounds
- containing mixture
- Prior art date
Links
- 208000023504 respiratory system disease Diseases 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title 1
- 150000002894 organic compounds Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003246 corticosteroid Substances 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 230000000414 obstructive effect Effects 0.000 abstract 1
- 150000003839 salts Chemical group 0.000 abstract 1
- 239000012453 solvate Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Abstract
A találmány tárgya egy gyógyászati készítmény, amely külön vagy együtttartalmazza (A) (I) képlet szerinti vegyületet szabad vagygyógyszerészetileg tolerálható só vagy szolvát formájában és (B)kortikoszteroidot szimultán, szakaszos vagy szeparált adagolásragyulladásos vagy obstruktív légúti megbetegedések kezelésére, az (A)és (B) moláris aránya 100:1 - 1:300. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0029562.6A GB0029562D0 (en) | 2000-12-04 | 2000-12-04 | Organic compounds |
PCT/EP2001/014122 WO2002045703A2 (en) | 2000-12-04 | 2001-12-03 | Mixtures or organic compounds for the treatmentof airway diseases |
Publications (3)
Publication Number | Publication Date |
---|---|
HUP0302571A2 true HUP0302571A2 (hu) | 2003-11-28 |
HUP0302571A3 HUP0302571A3 (en) | 2005-05-30 |
HU229552B1 HU229552B1 (en) | 2014-01-28 |
Family
ID=9904414
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0302571A HU229552B1 (en) | 2000-12-04 | 2001-12-03 | Pharmaceutical composition containing mixture of organic compounds for the treatment of air way diseases |
Country Status (28)
Country | Link |
---|---|
US (5) | US6800643B2 (hu) |
EP (2) | EP1341542B1 (hu) |
JP (2) | JP2004514739A (hu) |
KR (1) | KR100523541B1 (hu) |
CN (1) | CN1212119C (hu) |
AT (1) | ATE361077T1 (hu) |
AU (2) | AU1708202A (hu) |
BR (1) | BRPI0115910B8 (hu) |
CA (1) | CA2427282C (hu) |
CY (1) | CY1106727T1 (hu) |
CZ (1) | CZ304294B6 (hu) |
DE (1) | DE60128258T2 (hu) |
DK (1) | DK1341542T3 (hu) |
EC (1) | ECSP034620A (hu) |
ES (1) | ES2284732T3 (hu) |
GB (1) | GB0029562D0 (hu) |
HK (1) | HK1059564A1 (hu) |
HU (1) | HU229552B1 (hu) |
IL (2) | IL155709A0 (hu) |
MX (1) | MXPA03004976A (hu) |
NO (1) | NO325692B1 (hu) |
NZ (1) | NZ525731A (hu) |
PL (1) | PL204002B1 (hu) |
PT (1) | PT1341542E (hu) |
RU (1) | RU2292890C2 (hu) |
SK (1) | SK287331B6 (hu) |
WO (1) | WO2002045703A2 (hu) |
ZA (1) | ZA200303399B (hu) |
Families Citing this family (60)
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US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
AR028948A1 (es) | 2000-06-20 | 2003-05-28 | Astrazeneca Ab | Compuestos novedosos |
GB0029562D0 (en) * | 2000-12-04 | 2001-01-17 | Novartis Ag | Organic compounds |
ES2300568T3 (es) | 2002-03-20 | 2008-06-16 | Mannkind Corporation | Aparato de inhalacion. |
US20040146509A1 (en) * | 2002-07-25 | 2004-07-29 | Zhihe Li | Methods for improvement of lung function using TGF-beta inhibitors |
PA8578101A1 (es) | 2002-08-13 | 2004-05-07 | Warner Lambert Co | Derivados de heterobiarilo como inhibidores de metaloproteinasa de la matriz |
US7250426B2 (en) * | 2002-11-29 | 2007-07-31 | Boehringer Ingelheim Pharma Gmbh & Co Kg | Tiotropium-containing pharmaceutical combination for inhalation |
PE20100399A1 (es) * | 2003-04-02 | 2010-06-01 | Novartis Ag | Procedimiento para preparar oxi-(1h)-quinolin-2-onas 5-(alfa-haloacetil)-8-sustituidas |
EP1613315B1 (en) * | 2003-04-04 | 2009-01-21 | Novartis AG | Quinoline-2-one-derivatives for the treatment of airways diseases |
GB0307856D0 (en) * | 2003-04-04 | 2003-05-14 | Novartis Ag | Organic compounds |
GB0411056D0 (en) | 2004-05-18 | 2004-06-23 | Novartis Ag | Organic compounds |
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KR101306384B1 (ko) | 2004-08-23 | 2013-09-09 | 맨카인드 코포레이션 | 약물 전달용 디케토피페라진염, 디케토모르포린염 또는디케토디옥산염 |
KR100666220B1 (ko) * | 2005-01-31 | 2007-01-09 | 영남대학교 산학협력단 | 구내염 치료용 분사제 조성물 |
JP2008534611A (ja) * | 2005-03-30 | 2008-08-28 | シェーリング コーポレイション | 抗コリン作用薬、コルチコステロイドおよび長時間作用性βアゴニストを合わせる薬物および方法 |
GB0511065D0 (en) * | 2005-05-31 | 2005-07-06 | Novartis Ag | Organic compounds |
GB0511066D0 (en) * | 2005-05-31 | 2005-07-06 | Novartis Ag | Organic compounds |
TW200738634A (en) | 2005-08-02 | 2007-10-16 | Astrazeneca Ab | New salt |
TW200744612A (en) * | 2005-08-26 | 2007-12-16 | Astrazeneca Ab | New combination |
JP5465878B2 (ja) | 2005-09-14 | 2014-04-09 | マンカインド コーポレイション | 活性薬剤に対する結晶性微粒子表面の親和性を増大させることに基づく薬物処方の方法 |
GB0523655D0 (en) * | 2005-11-21 | 2005-12-28 | Novartis Ag | Organic compounds |
GB0523656D0 (en) * | 2005-11-21 | 2005-12-28 | Novartis Ag | Organic compounds |
EP1971346A2 (en) * | 2005-12-20 | 2008-09-24 | Tika Läkemedel AB | Systems and methods for the delivery of corticosteroids |
CN104383546B (zh) | 2006-02-22 | 2021-03-02 | 曼金德公司 | 用于改善包含二酮哌嗪和活性剂的微粒的药物性质的方法 |
US20070225233A1 (en) * | 2006-03-27 | 2007-09-27 | Tsu-Fuh Yeh | Reducing the risk of chronic lung disease in infants |
PT2044025E (pt) | 2006-06-30 | 2012-12-17 | Novartis Ag | Derivados de quinolinona e suas composições farmacêuticas |
EP1878722A1 (en) * | 2006-07-13 | 2008-01-16 | Novartis AG | Quinolinone derivatives and their pharmaceutical compositions |
EP2230934B8 (en) | 2007-12-14 | 2012-10-24 | AeroDesigns, Inc | Delivering aerosolizable food products |
CN104689432B (zh) | 2008-06-13 | 2018-07-06 | 曼金德公司 | 干粉吸入器和用于药物输送的系统 |
US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
JP5479465B2 (ja) | 2008-06-20 | 2014-04-23 | マンカインド コーポレイション | 吸入努力をリアルタイムにプロファイルする対話式機器および方法 |
TWI494123B (zh) | 2008-08-11 | 2015-08-01 | Mannkind Corp | 超快起作用胰島素之用途 |
US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
PL2405963T3 (pl) | 2009-03-11 | 2014-04-30 | Mannkind Corp | Urządzenie, układ i sposób pomiaru oporu inhalatora |
CN107412212B (zh) | 2009-05-29 | 2021-01-22 | 珍珠治疗公司 | 经肺递送长效毒蕈碱拮抗剂及长效β2肾上腺素能受体激动剂的组合物及相关方法与系统 |
EP2440184B1 (en) | 2009-06-12 | 2023-04-05 | MannKind Corporation | Diketopiperazine microparticles with defined specific surface areas |
KR100940388B1 (ko) * | 2009-07-01 | 2010-02-02 | 유병덕 | 스크류탈수기 및 이를 포함하는 유기성폐기물 건조장치 |
WO2011056889A1 (en) | 2009-11-03 | 2011-05-12 | Mannkind Corporation | An apparatus and method for simulating inhalation efforts |
RU2571331C1 (ru) | 2010-06-21 | 2015-12-20 | Маннкайнд Корпорейшн | Системы и способы доставки сухих порошковых лекарств |
WO2012007729A2 (en) * | 2010-07-16 | 2012-01-19 | Cipla Limited | Pharmaceutical compositions |
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WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
CN102247380A (zh) * | 2011-08-19 | 2011-11-23 | 北京阜康仁生物制药科技有限公司 | 一种以布地奈德与茚达特罗为活性成分的复方制剂 |
AU2012328885B2 (en) | 2011-10-24 | 2017-08-31 | Mannkind Corporation | Methods and compositions for treating pain |
WO2013132514A2 (en) * | 2012-03-09 | 2013-09-12 | Rao Davuluri Ramamohan | A novel process for the preparation of (r)-5-[2-[(5, 6-diethyl-2, 3-dihydro-1h-inden-2-yl) amino]-1-hydroxyethyl]-8-hydroxy quinolin-2(1h)-one |
WO2014008639A1 (zh) * | 2012-07-11 | 2014-01-16 | 上海威智医药科技有限公司 | 制备茚达特罗的方法 |
AU2013289957B2 (en) | 2012-07-12 | 2017-02-23 | Mannkind Corporation | Dry powder drug delivery systems and methods |
WO2014044288A1 (en) * | 2012-09-21 | 2014-03-27 | Crystal Pharma Sa | Methods for the preparation of indacaterol and pharmaceutically acceptable salts thereof |
WO2014066856A1 (en) | 2012-10-26 | 2014-05-01 | Mannkind Corporation | Inhalable influenza vaccine compositions and methods |
EP3587404B1 (en) | 2013-03-15 | 2022-07-13 | MannKind Corporation | Microcrystalline diketopiperazine compositions, methods for preparation and use thereof |
BR112016000937A8 (pt) | 2013-07-18 | 2021-06-22 | Mannkind Corp | formulações farmacêuticas de pó seco, método para a fabricação de uma formulação de pó seco e uso de uma formulação farmacêutica de pó seco |
JP2016530930A (ja) | 2013-08-05 | 2016-10-06 | マンカインド コーポレイション | 通気装置及び方法 |
WO2015148905A1 (en) | 2014-03-28 | 2015-10-01 | Mannkind Corporation | Use of ultrarapid acting insulin |
US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
ITUB20153978A1 (it) * | 2015-09-28 | 2017-03-28 | Laboratorio Chimico Int S P A | Procedimento per la preparazione di derivati di indanammina e di nuovi intermedi di sintesi. |
CN107868045A (zh) * | 2016-09-28 | 2018-04-03 | 四川海思科制药有限公司 | 一种茚达特罗中间体的制备方法 |
CN106831445B (zh) * | 2016-11-22 | 2019-01-22 | 斯芬克司药物研发(天津)股份有限公司 | 一种茚基胺化合物的制备方法 |
CN110229078A (zh) * | 2019-05-22 | 2019-09-13 | 博诺康源(北京)药业科技有限公司 | 一种茚达特罗起始原料开环杂质的制备 |
CN114751857A (zh) * | 2022-04-29 | 2022-07-15 | 梯尔希(南京)药物研发有限公司 | 一种茚达特罗杂质的制备方法 |
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US4607028A (en) * | 1983-08-18 | 1986-08-19 | Ciba-Geigy Corporation | Novel carboxylic acid esters |
WO1993018007A1 (en) * | 1992-03-13 | 1993-09-16 | Tokyo Tanabe Company Limited | Novel carbostyril derivative |
GB9405019D0 (en) * | 1994-03-15 | 1994-04-27 | Smithkline Beecham Plc | Novel compounds |
GB9501286D0 (en) * | 1995-01-24 | 1995-03-15 | Ciba Geigy Ag | Pharmaceutical compositions and preparations thereof |
ATE253908T1 (de) * | 1995-08-16 | 2003-11-15 | Huntington Medical Res Inst | Rhodamin 123 zusammensetzungen für behandlung von prostatakrebs |
GB9603237D0 (en) * | 1996-02-16 | 1996-04-17 | Sandoz Ltd | Organic compounds |
TW375604B (en) | 1996-02-19 | 1999-12-01 | Kissei Pharmaceutical | 3,4-di-substituting phenyl-ethanolamine-tetrahydronaphthyl carboxylic amide derivatives |
GB9610122D0 (en) | 1996-05-15 | 1996-07-24 | Reckitt & Colmann Prod Ltd | Organic compositions |
EP0997458A4 (en) | 1997-07-03 | 2003-03-05 | Asahi Chemical Ind | NOVEL TRICYCLIC COMPOUNDS HAVING SATUROUS CORES AND MEDICINAL COMPOSITIONS CONTAINING THEM |
GB9902689D0 (en) | 1999-02-08 | 1999-03-31 | Novartis Ag | Organic compounds |
GB9913083D0 (en) * | 1999-06-04 | 1999-08-04 | Novartis Ag | Organic compounds |
US6448239B1 (en) | 1999-06-03 | 2002-09-10 | Trustees Of Princeton University | Peroxynitrite decomposition catalysts and methods of use thereof |
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CA2417973A1 (en) * | 2000-08-04 | 2002-02-14 | Longwood Pharmaceutical Research, Inc. | Formulations of mometasone and a bronchodilator for pulmonary administration |
GB0029562D0 (en) * | 2000-12-04 | 2001-01-17 | Novartis Ag | Organic compounds |
-
2000
- 2000-12-04 GB GBGB0029562.6A patent/GB0029562D0/en not_active Ceased
-
2001
- 2001-12-03 CA CA2427282A patent/CA2427282C/en not_active Expired - Lifetime
- 2001-12-03 AT AT01999366T patent/ATE361077T1/de active
- 2001-12-03 PT PT01999366T patent/PT1341542E/pt unknown
- 2001-12-03 WO PCT/EP2001/014122 patent/WO2002045703A2/en active IP Right Grant
- 2001-12-03 DK DK01999366T patent/DK1341542T3/da active
- 2001-12-03 MX MXPA03004976A patent/MXPA03004976A/es active IP Right Grant
- 2001-12-03 KR KR10-2003-7005584A patent/KR100523541B1/ko active IP Right Grant
- 2001-12-03 DE DE60128258T patent/DE60128258T2/de not_active Expired - Lifetime
- 2001-12-03 SK SK650-2003A patent/SK287331B6/sk not_active IP Right Cessation
- 2001-12-03 IL IL15570901A patent/IL155709A0/xx active IP Right Grant
- 2001-12-03 AU AU1708202A patent/AU1708202A/xx active Pending
- 2001-12-03 EP EP01999366A patent/EP1341542B1/en not_active Expired - Lifetime
- 2001-12-03 BR BRPI0115910 patent/BRPI0115910B8/pt not_active IP Right Cessation
- 2001-12-03 ES ES01999366T patent/ES2284732T3/es not_active Expired - Lifetime
- 2001-12-03 NZ NZ525731A patent/NZ525731A/en not_active IP Right Cessation
- 2001-12-03 AU AU2002217082A patent/AU2002217082B2/en active Active
- 2001-12-03 US US10/433,546 patent/US6800643B2/en not_active Expired - Lifetime
- 2001-12-03 JP JP2002547487A patent/JP2004514739A/ja not_active Withdrawn
- 2001-12-03 HU HU0302571A patent/HU229552B1/hu unknown
- 2001-12-03 PL PL362443A patent/PL204002B1/pl unknown
- 2001-12-03 RU RU2003119549/15A patent/RU2292890C2/ru active
- 2001-12-03 CZ CZ2003-1537A patent/CZ304294B6/cs not_active IP Right Cessation
- 2001-12-03 CN CNB01820032XA patent/CN1212119C/zh not_active Expired - Lifetime
- 2001-12-03 EP EP07100048A patent/EP1772142A3/en not_active Withdrawn
-
2003
- 2003-05-01 IL IL155709A patent/IL155709A/en unknown
- 2003-05-02 ZA ZA200303399A patent/ZA200303399B/en unknown
- 2003-05-22 EC EC2003004620A patent/ECSP034620A/es unknown
- 2003-06-03 NO NO20032510A patent/NO325692B1/no not_active IP Right Cessation
-
2004
- 2004-02-11 HK HK04100918A patent/HK1059564A1/xx not_active IP Right Cessation
- 2004-08-04 US US10/911,201 patent/US7008951B2/en not_active Expired - Lifetime
-
2005
- 2005-10-12 US US11/248,462 patent/US7622484B2/en not_active Expired - Lifetime
-
2007
- 2007-07-10 JP JP2007180977A patent/JP2007302684A/ja active Pending
- 2007-07-13 CY CY20071100933T patent/CY1106727T1/el unknown
-
2009
- 2009-10-09 US US12/576,444 patent/US20100068288A1/en not_active Abandoned
-
2012
- 2012-01-09 US US13/346,108 patent/US20120108555A1/en not_active Abandoned
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