DK1341542T3 - Indanylderivater til behandling af luftvejssygdomme - Google Patents
Indanylderivater til behandling af luftvejssygdommeInfo
- Publication number
- DK1341542T3 DK1341542T3 DK01999366T DK01999366T DK1341542T3 DK 1341542 T3 DK1341542 T3 DK 1341542T3 DK 01999366 T DK01999366 T DK 01999366T DK 01999366 T DK01999366 T DK 01999366T DK 1341542 T3 DK1341542 T3 DK 1341542T3
- Authority
- DK
- Denmark
- Prior art keywords
- treatment
- respiratory diseases
- indanyl derivatives
- indanyl
- derivatives
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Quinoline Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0029562.6A GB0029562D0 (en) | 2000-12-04 | 2000-12-04 | Organic compounds |
PCT/EP2001/014122 WO2002045703A2 (en) | 2000-12-04 | 2001-12-03 | Mixtures or organic compounds for the treatmentof airway diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1341542T3 true DK1341542T3 (da) | 2007-09-03 |
Family
ID=9904414
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK01999366T DK1341542T3 (da) | 2000-12-04 | 2001-12-03 | Indanylderivater til behandling af luftvejssygdomme |
Country Status (28)
Country | Link |
---|---|
US (5) | US6800643B2 (da) |
EP (2) | EP1772142A3 (da) |
JP (2) | JP2004514739A (da) |
KR (1) | KR100523541B1 (da) |
CN (1) | CN1212119C (da) |
AT (1) | ATE361077T1 (da) |
AU (2) | AU1708202A (da) |
BR (1) | BRPI0115910B8 (da) |
CA (1) | CA2427282C (da) |
CY (1) | CY1106727T1 (da) |
CZ (1) | CZ304294B6 (da) |
DE (1) | DE60128258T2 (da) |
DK (1) | DK1341542T3 (da) |
EC (1) | ECSP034620A (da) |
ES (1) | ES2284732T3 (da) |
GB (1) | GB0029562D0 (da) |
HK (1) | HK1059564A1 (da) |
HU (1) | HU229552B1 (da) |
IL (2) | IL155709A0 (da) |
MX (1) | MXPA03004976A (da) |
NO (1) | NO325692B1 (da) |
NZ (1) | NZ525731A (da) |
PL (1) | PL204002B1 (da) |
PT (1) | PT1341542E (da) |
RU (1) | RU2292890C2 (da) |
SK (1) | SK287331B6 (da) |
WO (1) | WO2002045703A2 (da) |
ZA (1) | ZA200303399B (da) |
Families Citing this family (60)
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---|---|---|---|---|
US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
AR028948A1 (es) | 2000-06-20 | 2003-05-28 | Astrazeneca Ab | Compuestos novedosos |
GB0029562D0 (en) * | 2000-12-04 | 2001-01-17 | Novartis Ag | Organic compounds |
ATE385193T1 (de) | 2002-03-20 | 2008-02-15 | Mannkind Corp | Inhalationsgerät |
US20040146509A1 (en) * | 2002-07-25 | 2004-07-29 | Zhihe Li | Methods for improvement of lung function using TGF-beta inhibitors |
PA8578101A1 (es) | 2002-08-13 | 2004-05-07 | Warner Lambert Co | Derivados de heterobiarilo como inhibidores de metaloproteinasa de la matriz |
US7250426B2 (en) * | 2002-11-29 | 2007-07-31 | Boehringer Ingelheim Pharma Gmbh & Co Kg | Tiotropium-containing pharmaceutical combination for inhalation |
PE20050211A1 (es) * | 2003-04-02 | 2005-04-27 | Novartis Ag | Procedimiento para preparar oxi-(1h)-quinolin-2-onas 5-(alfa-haloacetil)-8-sustituidas |
GB0307856D0 (en) * | 2003-04-04 | 2003-05-14 | Novartis Ag | Organic compounds |
EP1613315B1 (en) * | 2003-04-04 | 2009-01-21 | Novartis AG | Quinoline-2-one-derivatives for the treatment of airways diseases |
GB0411056D0 (en) | 2004-05-18 | 2004-06-23 | Novartis Ag | Organic compounds |
CA2575692C (en) | 2004-08-20 | 2014-10-14 | Mannkind Corporation | Catalysis of diketopiperazine synthesis |
BR122019022692B1 (pt) | 2004-08-23 | 2023-01-10 | Mannkind Corporation | Composição terapêutica em pó seco contendo dicetopiperazina, pelo menos um tipo de cátion e um agente biologicamente ativo |
KR100666220B1 (ko) * | 2005-01-31 | 2007-01-09 | 영남대학교 산학협력단 | 구내염 치료용 분사제 조성물 |
WO2006105401A2 (en) * | 2005-03-30 | 2006-10-05 | Schering Corporation | Medicaments and methods combining an anticholinergic, a corticosteroid, and a long acting beta agonist |
GB0511066D0 (en) * | 2005-05-31 | 2005-07-06 | Novartis Ag | Organic compounds |
GB0511065D0 (en) * | 2005-05-31 | 2005-07-06 | Novartis Ag | Organic compounds |
TW200738634A (en) | 2005-08-02 | 2007-10-16 | Astrazeneca Ab | New salt |
TW200744612A (en) * | 2005-08-26 | 2007-12-16 | Astrazeneca Ab | New combination |
DK1937219T3 (da) | 2005-09-14 | 2016-02-15 | Mannkind Corp | Fremgangsmåde til lægemiddelformulering baseret på at øge affiniteten af krystallinske mikropartikeloverflader til aktive stoffer |
GB0523655D0 (en) * | 2005-11-21 | 2005-12-28 | Novartis Ag | Organic compounds |
GB0523656D0 (en) * | 2005-11-21 | 2005-12-28 | Novartis Ag | Organic compounds |
EP1971348A2 (en) * | 2005-12-20 | 2008-09-24 | Tika Läkemedel AB | Systems and methods for the delivery of corticosteroids having an increased lung deposition |
IN2015DN00888A (da) | 2006-02-22 | 2015-07-10 | Mannkind Corp | |
US20070225233A1 (en) * | 2006-03-27 | 2007-09-27 | Tsu-Fuh Yeh | Reducing the risk of chronic lung disease in infants |
US8198450B2 (en) * | 2006-06-30 | 2012-06-12 | Novartis Ag | Quinolinone derivatives and their pharmaceutical compositions |
EP1878722A1 (en) * | 2006-07-13 | 2008-01-16 | Novartis AG | Quinolinone derivatives and their pharmaceutical compositions |
EP2534957B1 (en) | 2007-12-14 | 2015-05-27 | AeroDesigns, Inc | Delivering aerosolizable products |
US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
KR101933816B1 (ko) | 2008-06-13 | 2019-03-29 | 맨카인드 코포레이션 | 건조 분말 흡입기 및 약물 투여 시스템 |
EP2609954B1 (en) | 2008-06-20 | 2021-12-29 | MannKind Corporation | An interactive apparatus for real-time profiling of inhalation efforts |
TWI532497B (zh) | 2008-08-11 | 2016-05-11 | 曼凱公司 | 超快起作用胰島素之用途 |
US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
US8538707B2 (en) | 2009-03-11 | 2013-09-17 | Mannkind Corporation | Apparatus, system and method for measuring resistance of an inhaler |
RU2580315C3 (ru) | 2009-05-29 | 2021-06-18 | Перл Терапьютикс, Инк. | Композиции для респираторной доставки активных веществ и связанные с ними способы и системы |
MY157166A (en) | 2009-06-12 | 2016-05-13 | Mankind Corp | Diketopiperazine microparticles with defined specific surface areas |
KR100940388B1 (ko) * | 2009-07-01 | 2010-02-02 | 유병덕 | 스크류탈수기 및 이를 포함하는 유기성폐기물 건조장치 |
JP5784622B2 (ja) | 2009-11-03 | 2015-09-24 | マンカインド コーポレ−ション | 吸入活動をシミュレートするための装置及び方法 |
RU2531455C2 (ru) | 2010-06-21 | 2014-10-20 | Маннкайнд Корпорейшн | Системы и способы доставки сухих порошковых лекарств |
EP3871676A1 (en) * | 2010-07-16 | 2021-09-01 | Cipla Limited | Pharmaceutical compositions comprising r(+) budesonide and arformoterol |
CN107998109A (zh) * | 2010-10-12 | 2018-05-08 | 西普拉有限公司 | 药物组合物 |
JP6133270B2 (ja) | 2011-04-01 | 2017-05-24 | マンカインド コーポレイション | 薬剤カートリッジのためのブリスター包装 |
WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
CN102247380A (zh) * | 2011-08-19 | 2011-11-23 | 北京阜康仁生物制药科技有限公司 | 一种以布地奈德与茚达特罗为活性成分的复方制剂 |
CA2852536A1 (en) | 2011-10-24 | 2013-05-02 | Mannkind Corporation | Methods and compositions for treating pain |
WO2013132514A2 (en) * | 2012-03-09 | 2013-09-12 | Rao Davuluri Ramamohan | A novel process for the preparation of (r)-5-[2-[(5, 6-diethyl-2, 3-dihydro-1h-inden-2-yl) amino]-1-hydroxyethyl]-8-hydroxy quinolin-2(1h)-one |
WO2014008639A1 (zh) * | 2012-07-11 | 2014-01-16 | 上海威智医药科技有限公司 | 制备茚达特罗的方法 |
ES2624294T3 (es) | 2012-07-12 | 2017-07-13 | Mannkind Corporation | Sistemas de suministro de fármacos en polvo seco |
WO2014044288A1 (en) * | 2012-09-21 | 2014-03-27 | Crystal Pharma Sa | Methods for the preparation of indacaterol and pharmaceutically acceptable salts thereof |
EP2911690A1 (en) | 2012-10-26 | 2015-09-02 | MannKind Corporation | Inhalable influenza vaccine compositions and methods |
EP2970149B1 (en) | 2013-03-15 | 2019-08-21 | MannKind Corporation | Microcrystalline diketopiperazine compositions and methods |
BR112016000937A8 (pt) | 2013-07-18 | 2021-06-22 | Mannkind Corp | formulações farmacêuticas de pó seco, método para a fabricação de uma formulação de pó seco e uso de uma formulação farmacêutica de pó seco |
CA2920488C (en) | 2013-08-05 | 2022-04-26 | Mannkind Corporation | Insufflation apparatus and methods |
WO2015148905A1 (en) | 2014-03-28 | 2015-10-01 | Mannkind Corporation | Use of ultrarapid acting insulin |
US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
ITUB20153978A1 (it) * | 2015-09-28 | 2017-03-28 | Laboratorio Chimico Int S P A | Procedimento per la preparazione di derivati di indanammina e di nuovi intermedi di sintesi. |
CN107868045A (zh) * | 2016-09-28 | 2018-04-03 | 四川海思科制药有限公司 | 一种茚达特罗中间体的制备方法 |
CN106831445B (zh) * | 2016-11-22 | 2019-01-22 | 斯芬克司药物研发(天津)股份有限公司 | 一种茚基胺化合物的制备方法 |
CN110229078A (zh) * | 2019-05-22 | 2019-09-13 | 博诺康源(北京)药业科技有限公司 | 一种茚达特罗起始原料开环杂质的制备 |
CN114751857A (zh) * | 2022-04-29 | 2022-07-15 | 梯尔希(南京)药物研发有限公司 | 一种茚达特罗杂质的制备方法 |
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US4607028A (en) * | 1983-08-18 | 1986-08-19 | Ciba-Geigy Corporation | Novel carboxylic acid esters |
WO1993018007A1 (en) * | 1992-03-13 | 1993-09-16 | Tokyo Tanabe Company Limited | Novel carbostyril derivative |
GB9405019D0 (en) | 1994-03-15 | 1994-04-27 | Smithkline Beecham Plc | Novel compounds |
GB9501286D0 (en) * | 1995-01-24 | 1995-03-15 | Ciba Geigy Ag | Pharmaceutical compositions and preparations thereof |
EP0761216B1 (en) * | 1995-08-16 | 2003-11-12 | Huntington Medical Research Institutes | Rhodamine 123 compositions for treating prostate cancer |
GB9603237D0 (en) | 1996-02-16 | 1996-04-17 | Sandoz Ltd | Organic compounds |
TW375604B (en) | 1996-02-19 | 1999-12-01 | Kissei Pharmaceutical | 3,4-di-substituting phenyl-ethanolamine-tetrahydronaphthyl carboxylic amide derivatives |
GB9610122D0 (en) | 1996-05-15 | 1996-07-24 | Reckitt & Colmann Prod Ltd | Organic compositions |
KR100335169B1 (ko) | 1997-07-03 | 2002-05-04 | 야마모토 카즈모토 | 포화 고리를 갖는 신규한 트리시클릭 화합물 및 이를포함하는 의약 조성물 |
GB9902689D0 (en) | 1999-02-08 | 1999-03-31 | Novartis Ag | Organic compounds |
GB9913083D0 (en) * | 1999-06-04 | 1999-08-04 | Novartis Ag | Organic compounds |
US6448239B1 (en) | 1999-06-03 | 2002-09-10 | Trustees Of Princeton University | Peroxynitrite decomposition catalysts and methods of use thereof |
US6664235B1 (en) | 1999-08-20 | 2003-12-16 | Riken | Medicaments comprising sialic acid derivatives as active ingredients |
CA2417973A1 (en) * | 2000-08-04 | 2002-02-14 | Longwood Pharmaceutical Research, Inc. | Formulations of mometasone and a bronchodilator for pulmonary administration |
GB0029562D0 (en) * | 2000-12-04 | 2001-01-17 | Novartis Ag | Organic compounds |
-
2000
- 2000-12-04 GB GBGB0029562.6A patent/GB0029562D0/en not_active Ceased
-
2001
- 2001-12-03 IL IL15570901A patent/IL155709A0/xx active IP Right Grant
- 2001-12-03 NZ NZ525731A patent/NZ525731A/en not_active IP Right Cessation
- 2001-12-03 PT PT01999366T patent/PT1341542E/pt unknown
- 2001-12-03 KR KR10-2003-7005584A patent/KR100523541B1/ko active IP Right Grant
- 2001-12-03 HU HU0302571A patent/HU229552B1/hu unknown
- 2001-12-03 WO PCT/EP2001/014122 patent/WO2002045703A2/en active IP Right Grant
- 2001-12-03 CZ CZ2003-1537A patent/CZ304294B6/cs not_active IP Right Cessation
- 2001-12-03 DK DK01999366T patent/DK1341542T3/da active
- 2001-12-03 AU AU1708202A patent/AU1708202A/xx active Pending
- 2001-12-03 EP EP07100048A patent/EP1772142A3/en not_active Withdrawn
- 2001-12-03 MX MXPA03004976A patent/MXPA03004976A/es active IP Right Grant
- 2001-12-03 JP JP2002547487A patent/JP2004514739A/ja not_active Withdrawn
- 2001-12-03 DE DE60128258T patent/DE60128258T2/de not_active Expired - Lifetime
- 2001-12-03 CA CA2427282A patent/CA2427282C/en not_active Expired - Lifetime
- 2001-12-03 BR BRPI0115910 patent/BRPI0115910B8/pt not_active IP Right Cessation
- 2001-12-03 ES ES01999366T patent/ES2284732T3/es not_active Expired - Lifetime
- 2001-12-03 SK SK650-2003A patent/SK287331B6/sk not_active IP Right Cessation
- 2001-12-03 PL PL362443A patent/PL204002B1/pl unknown
- 2001-12-03 US US10/433,546 patent/US6800643B2/en not_active Expired - Lifetime
- 2001-12-03 RU RU2003119549/15A patent/RU2292890C2/ru active
- 2001-12-03 CN CNB01820032XA patent/CN1212119C/zh not_active Expired - Lifetime
- 2001-12-03 EP EP01999366A patent/EP1341542B1/en not_active Expired - Lifetime
- 2001-12-03 AT AT01999366T patent/ATE361077T1/de active
- 2001-12-03 AU AU2002217082A patent/AU2002217082B2/en active Active
-
2003
- 2003-05-01 IL IL155709A patent/IL155709A/en unknown
- 2003-05-02 ZA ZA200303399A patent/ZA200303399B/en unknown
- 2003-05-22 EC EC2003004620A patent/ECSP034620A/es unknown
- 2003-06-03 NO NO20032510A patent/NO325692B1/no not_active IP Right Cessation
-
2004
- 2004-02-11 HK HK04100918A patent/HK1059564A1/xx not_active IP Right Cessation
- 2004-08-04 US US10/911,201 patent/US7008951B2/en not_active Expired - Lifetime
-
2005
- 2005-10-12 US US11/248,462 patent/US7622484B2/en not_active Expired - Lifetime
-
2007
- 2007-07-10 JP JP2007180977A patent/JP2007302684A/ja active Pending
- 2007-07-13 CY CY20071100933T patent/CY1106727T1/el unknown
-
2009
- 2009-10-09 US US12/576,444 patent/US20100068288A1/en not_active Abandoned
-
2012
- 2012-01-09 US US13/346,108 patent/US20120108555A1/en not_active Abandoned
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