BR0011094A - Polimorfos de um citrato cristalino de azobiciclo[2,2,2]octan-3-amina e suas composições farmacêuticas - Google Patents

Polimorfos de um citrato cristalino de azobiciclo[2,2,2]octan-3-amina e suas composições farmacêuticas

Info

Publication number
BR0011094A
BR0011094A BR0011094-9A BR0011094A BR0011094A BR 0011094 A BR0011094 A BR 0011094A BR 0011094 A BR0011094 A BR 0011094A BR 0011094 A BR0011094 A BR 0011094A
Authority
BR
Brazil
Prior art keywords
octan
crystalline
citrate
azobicyclo
pharmaceutical compositions
Prior art date
Application number
BR0011094-9A
Other languages
English (en)
Inventor
Michael James Castaldi
George Joseph Quallich
Lewin Theophiluswint
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of BR0011094A publication Critical patent/BR0011094A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Otolaryngology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Patente de Invenção: "POLIMORFOS DE UM CITRATO CRISTALINO DE AZOBICICLO[2,2,2]OCTAN-3-AMINA E SUAS COMPOSIçõES FARMACêUTICAS". Uma forma polimórfica cristalina individual de citrato de (2S, 3S)-N-(metoxi-5-t-butilfenilmetil-2-difenilmetil-1 -azobiciclo[2,2,2]octan-3-amina (monohidrato de citrato) e sua composição farmacêutica. A composição farmacêutica da forma polimórfica do monohidrato de citrato tem estabilidade vantajosa para formulação para tratamento de êmese. A administração desta composição farmacêutica é de libertação imediata, a forma de dosagem oral preferencialmente por comprimido ou cápsula ou intravenosa.
BR0011094-9A 1999-06-01 2000-05-18 Polimorfos de um citrato cristalino de azobiciclo[2,2,2]octan-3-amina e suas composições farmacêuticas BR0011094A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13699299P 1999-06-01 1999-06-01
PCT/IB2000/000665 WO2000073304A1 (en) 1999-06-01 2000-05-18 Polymorphs of a crystalline azabicyclo (2,2,2) octan-3-amine citrate and their pharmaceutical compositions

Publications (1)

Publication Number Publication Date
BR0011094A true BR0011094A (pt) 2002-03-19

Family

ID=22475338

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0011094-9A BR0011094A (pt) 1999-06-01 2000-05-18 Polimorfos de um citrato cristalino de azobiciclo[2,2,2]octan-3-amina e suas composições farmacêuticas

Country Status (49)

Country Link
US (1) US6255320B1 (pt)
EP (1) EP1181290B1 (pt)
JP (1) JP3830816B2 (pt)
KR (1) KR100476606B1 (pt)
CN (1) CN1146565C (pt)
AP (1) AP2001002349A0 (pt)
AR (1) AR033331A1 (pt)
AT (1) ATE244239T1 (pt)
AU (1) AU767334B2 (pt)
BG (1) BG65240B1 (pt)
BR (1) BR0011094A (pt)
CA (1) CA2372238C (pt)
CO (1) CO5170463A1 (pt)
CY (1) CY2007011I1 (pt)
CZ (1) CZ295819B6 (pt)
DE (1) DE60003679T2 (pt)
DK (1) DK1181290T3 (pt)
DZ (1) DZ3050A1 (pt)
EA (1) EA003731B1 (pt)
EC (1) ECSP003508A (pt)
EE (1) EE200100656A (pt)
ES (1) ES2199825T3 (pt)
GT (1) GT200000087A (pt)
HK (1) HK1046284A1 (pt)
HN (1) HN2000000077A (pt)
HR (1) HRP20010904A2 (pt)
HU (1) HUP0201301A3 (pt)
IL (1) IL146406A0 (pt)
MA (1) MA26742A1 (pt)
MX (1) MXPA01012325A (pt)
MY (1) MY133508A (pt)
NO (1) NO20015848L (pt)
NZ (1) NZ515349A (pt)
OA (1) OA11956A (pt)
PA (1) PA8496101A1 (pt)
PE (1) PE20010209A1 (pt)
PL (1) PL196046B1 (pt)
PT (1) PT1181290E (pt)
SI (1) SI1181290T1 (pt)
SK (1) SK285820B6 (pt)
SV (1) SV2001000093A (pt)
TN (1) TNSN00120A1 (pt)
TR (1) TR200103473T2 (pt)
TW (1) TWI285204B (pt)
UA (1) UA66925C2 (pt)
UY (1) UY26176A1 (pt)
WO (1) WO2000073304A1 (pt)
YU (1) YU81101A (pt)
ZA (1) ZA200109775B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA06008648A (es) * 2004-01-30 2006-09-04 Pfizer Prod Inc Composiciones farmaceuticas de antagonistas del receptor de neuroquinina y ciclodextrina y metodos para una tolerancia mejorada en el sitio de inyeccion.
SI1713504T1 (sl) * 2004-01-30 2017-10-30 Zoetis Services Llc Protimikrobni konzervansi za dosego večodmerne formulacije z uporabo beta-ciklodekstrinov za tekoče odmerne oblike
AU2005216706B2 (en) 2004-01-30 2007-11-29 Pfizer Products Inc. NK-1 receptor antagonists anesthesia recovery
AU2005210259A1 (en) * 2004-02-02 2005-08-18 Pfizer Products Inc. Process for preparation of 1-(2S,3S)-2-benzhydr yl-N-(5-tert-butyl-2-methoxybenzyl)quinuclidin-3-amine
WO2014144894A1 (en) * 2013-03-15 2014-09-18 Pearl Therapeutics, Inc. Methods and systems for conditioning of particulate crystalline materials
CN110577522B (zh) * 2018-06-07 2022-12-27 东莞市东阳光动物保健药品有限公司 马罗匹坦柠檬酸盐新晶型及其制备方法
CN112979639A (zh) * 2019-12-16 2021-06-18 四川科瑞德凯华制药有限公司 一种马罗皮坦新晶型及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2103269C1 (ru) * 1991-05-31 1998-01-27 Пфайзер Инк. Производные хинуклидина или их фармацевтически приемлемые соли и фармацевтическая композиция
US5393762A (en) * 1993-06-04 1995-02-28 Pfizer Inc. Pharmaceutical agents for treatment of emesis
US5576317A (en) * 1994-12-09 1996-11-19 Pfizer Inc. NK-1 receptor antagonists and 5HT3 receptor antagonists for the treatment of emesis

Also Published As

Publication number Publication date
JP2003501354A (ja) 2003-01-14
IL146406A0 (en) 2002-07-25
UA66925C2 (uk) 2004-06-15
EP1181290B1 (en) 2003-07-02
AU767334B2 (en) 2003-11-06
BG65240B1 (bg) 2007-09-28
DZ3050A1 (fr) 2004-03-27
TWI285204B (en) 2007-08-11
AU4424800A (en) 2000-12-18
CY2007011I2 (el) 2010-07-28
DE60003679D1 (de) 2003-08-07
NO20015848L (no) 2001-12-18
US6255320B1 (en) 2001-07-03
DE60003679T2 (de) 2004-05-27
HUP0201301A2 (en) 2002-08-28
HK1046284A1 (en) 2003-01-03
AP2001002349A0 (en) 2001-12-31
MA26742A1 (fr) 2004-12-20
KR20020010688A (ko) 2002-02-04
TR200103473T2 (tr) 2002-04-22
PL352716A1 (en) 2003-09-08
ES2199825T3 (es) 2004-03-01
SK17332001A3 (sk) 2002-07-02
EE200100656A (et) 2003-02-17
PA8496101A1 (es) 2002-07-30
PT1181290E (pt) 2003-09-30
ATE244239T1 (de) 2003-07-15
ECSP003508A (es) 2002-02-25
CZ20014269A3 (cs) 2002-04-17
NO20015848D0 (no) 2001-11-30
CA2372238A1 (en) 2000-12-07
CN1353711A (zh) 2002-06-12
YU81101A (sh) 2004-07-15
SV2001000093A (es) 2001-11-08
DK1181290T3 (da) 2003-09-29
CY2007011I1 (el) 2010-07-28
OA11956A (en) 2006-04-13
EP1181290A1 (en) 2002-02-27
UY26176A1 (es) 2000-12-29
BG106204A (en) 2002-07-31
CO5170463A1 (es) 2002-06-27
CN1146565C (zh) 2004-04-21
EA200101108A1 (ru) 2002-04-25
JP3830816B2 (ja) 2006-10-11
AR033331A1 (es) 2003-12-17
SK285820B6 (sk) 2007-09-06
EA003731B1 (ru) 2003-08-28
CZ295819B6 (cs) 2005-11-16
PL196046B1 (pl) 2007-11-30
GT200000087A (es) 2001-11-22
HN2000000077A (es) 2001-02-02
SI1181290T1 (en) 2003-12-31
ZA200109775B (en) 2002-11-28
HRP20010904A2 (en) 2003-02-28
WO2000073304A1 (en) 2000-12-07
NZ515349A (en) 2004-03-26
HUP0201301A3 (en) 2002-10-28
MY133508A (en) 2007-11-30
KR100476606B1 (ko) 2005-03-18
TNSN00120A1 (fr) 2005-11-10
CA2372238C (en) 2006-12-19
MXPA01012325A (es) 2002-07-22
PE20010209A1 (es) 2001-03-01

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O, 11, 13, 24 E 25 DA LPI

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.