HUP0400495A2 - Apomorfin szájnyálkahártyán keresztül történő adagolására szolgáló orális készítmény - Google Patents
Apomorfin szájnyálkahártyán keresztül történő adagolására szolgáló orális készítményInfo
- Publication number
- HUP0400495A2 HUP0400495A2 HU0400495A HUP0400495A HUP0400495A2 HU P0400495 A2 HUP0400495 A2 HU P0400495A2 HU 0400495 A HU0400495 A HU 0400495A HU P0400495 A HUP0400495 A HU P0400495A HU P0400495 A2 HUP0400495 A2 HU P0400495A2
- Authority
- HU
- Hungary
- Prior art keywords
- oral mucosal
- apomorphine
- dosage forms
- administration via
- tissue
- Prior art date
Links
- VMWNQDUVQKEIOC-CYBMUJFWSA-N apomorphine Chemical compound C([C@H]1N(C)CC2)C3=CC=C(O)C(O)=C3C3=C1C2=CC=C3 VMWNQDUVQKEIOC-CYBMUJFWSA-N 0.000 title abstract 3
- 229960004046 apomorphine Drugs 0.000 title abstract 3
- 239000002552 dosage form Substances 0.000 title abstract 2
- 210000004400 mucous membrane Anatomy 0.000 title 1
- 229920002307 Dextran Polymers 0.000 abstract 2
- 239000012876 carrier material Substances 0.000 abstract 1
- 210000002200 mouth mucosa Anatomy 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Zoology (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Abstract
A találmány tárgya gyógyszerkészítmény, amely apomorfin vagygyógyszerészetileg elfogadható sója vagy prodrugja terápiásan hatásosmennyiségét tartalmazza egy 10-95 tömeg%-ban dextránt tartalmazóhordozóval kombinációban. A találmány oltalmi körébe tartozik egy azapomorfin szájnyálkahártyán keresztül történő adagolására szolgálótabletta dózis forma is, amely 2-10 mg apomorfint tartalmaz 10-95 mgdextránt tartalmazó hordozóanyaggal kombinációban. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US47584499A | 1999-12-30 | 1999-12-30 | |
PCT/US2000/034548 WO2001049292A1 (en) | 1999-12-30 | 2000-12-19 | Oral mucosal dosage forms of apomorphine |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0400495A2 true HUP0400495A2 (hu) | 2004-06-28 |
HUP0400495A3 HUP0400495A3 (en) | 2007-05-02 |
Family
ID=23889387
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0400495A HUP0400495A3 (en) | 1999-12-30 | 2000-12-19 | Oral mucosal dosage forms of apomorphine, suitable for the administration via oral mucosal tissue |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP1242088A1 (hu) |
JP (1) | JP2004501065A (hu) |
CN (1) | CN1414853A (hu) |
AU (1) | AU2440901A (hu) |
BR (1) | BR0012822A (hu) |
CA (1) | CA2394297A1 (hu) |
CZ (1) | CZ20022245A3 (hu) |
HK (1) | HK1051315A1 (hu) |
HU (1) | HUP0400495A3 (hu) |
IL (1) | IL150034A0 (hu) |
MX (1) | MXPA02006034A (hu) |
NO (1) | NO20023190L (hu) |
PL (1) | PL366204A1 (hu) |
WO (1) | WO2001049292A1 (hu) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE0202365D0 (sv) | 2002-08-05 | 2002-08-05 | Pharmacia Ab | New formulation and use thereof |
SI1617823T1 (sl) * | 2003-01-24 | 2019-07-31 | Nicachet Ab | Vrečka, ki obsega nikotinski sestavek za transmukozno dajanje |
SE0302947D0 (sv) | 2003-01-24 | 2003-11-07 | Magle Ab | A composition material for transmucosal delivery |
CA2562391A1 (en) * | 2004-04-14 | 2005-10-27 | Takeda Pharmaceutical Company Limited | Solid pharmaceutical preparation |
GB0509317D0 (en) * | 2005-05-06 | 2005-06-15 | Clarke Anthony | Pharmaceutical formulation of apomorphine |
AU2010259971C1 (en) * | 2009-06-12 | 2017-02-16 | Sunovion Pharmaceuticals Inc. | Sublingual apomorphine |
WO2020243538A1 (en) * | 2019-05-31 | 2020-12-03 | Primo Pharmatech Llc | Unit dosage form for transmucosal drug delivery of an active pharmaceutical ingredient |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK0865789T3 (da) * | 1993-03-26 | 2005-07-18 | Franciscus Wilhelmus He Merkus | Farmaceutiske præparater til intranasal administration af dihydroergotamin |
GB9517062D0 (en) * | 1995-08-18 | 1995-10-25 | Scherer Ltd R P | Pharmaceutical compositions |
-
2000
- 2000-12-19 CN CN00818098A patent/CN1414853A/zh active Pending
- 2000-12-19 IL IL15003400A patent/IL150034A0/xx unknown
- 2000-12-19 BR BR0012822-8A patent/BR0012822A/pt not_active IP Right Cessation
- 2000-12-19 WO PCT/US2000/034548 patent/WO2001049292A1/en not_active Application Discontinuation
- 2000-12-19 AU AU24409/01A patent/AU2440901A/en not_active Abandoned
- 2000-12-19 PL PL00366204A patent/PL366204A1/xx not_active Application Discontinuation
- 2000-12-19 JP JP2001549660A patent/JP2004501065A/ja not_active Withdrawn
- 2000-12-19 CZ CZ20022245A patent/CZ20022245A3/cs unknown
- 2000-12-19 CA CA002394297A patent/CA2394297A1/en not_active Abandoned
- 2000-12-19 HU HU0400495A patent/HUP0400495A3/hu unknown
- 2000-12-19 MX MXPA02006034A patent/MXPA02006034A/es unknown
- 2000-12-19 EP EP00988174A patent/EP1242088A1/en not_active Withdrawn
-
2002
- 2002-07-01 NO NO20023190A patent/NO20023190L/no not_active Application Discontinuation
-
2003
- 2003-03-14 HK HK03101912.0A patent/HK1051315A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
WO2001049292A1 (en) | 2001-07-12 |
PL366204A1 (en) | 2005-01-24 |
EP1242088A1 (en) | 2002-09-25 |
BR0012822A (pt) | 2004-03-09 |
CA2394297A1 (en) | 2001-07-12 |
NO20023190L (no) | 2002-08-29 |
AU2440901A (en) | 2001-07-16 |
JP2004501065A (ja) | 2004-01-15 |
CZ20022245A3 (cs) | 2002-10-16 |
HK1051315A1 (zh) | 2003-08-01 |
CN1414853A (zh) | 2003-04-30 |
IL150034A0 (en) | 2002-12-01 |
MXPA02006034A (es) | 2004-08-23 |
NO20023190D0 (no) | 2002-07-01 |
HUP0400495A3 (en) | 2007-05-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD9A | Lapse of provisional protection due to non-payment of fees |