ES2115571T3 - Uso de polisulfato de pentosana para la resolucion de cicatrices en enfermedades vasculares progresivas cronicas. - Google Patents

Uso de polisulfato de pentosana para la resolucion de cicatrices en enfermedades vasculares progresivas cronicas.

Info

Publication number
ES2115571T3
ES2115571T3 ES96917917T ES96917917T ES2115571T3 ES 2115571 T3 ES2115571 T3 ES 2115571T3 ES 96917917 T ES96917917 T ES 96917917T ES 96917917 T ES96917917 T ES 96917917T ES 2115571 T3 ES2115571 T3 ES 2115571T3
Authority
ES
Spain
Prior art keywords
pps
chronic progressive
polisulfate
pentosana
scars
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96917917T
Other languages
English (en)
Other versions
ES2115571T1 (es
Inventor
Gary E Striker
Liliane J Striker
Fred P Sherman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Department of Health and Human Services
Ivax Research Holdings Inc
Original Assignee
US Department of Health and Human Services
Ivax Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Department of Health and Human Services, Ivax Research Inc filed Critical US Department of Health and Human Services
Publication of ES2115571T1 publication Critical patent/ES2115571T1/es
Application granted granted Critical
Publication of ES2115571T3 publication Critical patent/ES2115571T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Abstract

LA INVENCION SE REFIERE A UN METODO PARA EL TRATAMIENTO DE UN PACIENTE MAMIFERO QUE SUFRE UNA ENFERMEDAD VASCULAR PROGRESIVA CRONICA (CPVD) CARACTERIZADA POR CICATRIZACION Y/O FIBROSIS CON EL FIN DE DETENER EL PROGRESO DE LA ENFERMEDAD Y RESOLVER LAS LESIONES DE CICATRIZACION O FIBROTICAS YA FORMADAS. EL METODO CONSISTE EN ADMINISTRAR AL PACIENTE UNA COMPOSICION FARMACEUTICA QUE CONTIENE UNA CANTIDAD EFICAZ DE POLISULFATO DE PENTOSANO (PPS) O UNA SAL FARMACEUTICAMENTE ACEPTABLE DEL MISMO. SE PREFIERE LA VIA ORAL DE ADMINISTRACION, CON DOSIS DIARIAS TOTALES DE PPS O DE SAL DE PPS DE ENTRE APROXIMADAMENTE 50 Y 1200 MG POR DIA.
ES96917917T 1995-06-07 1996-06-03 Uso de polisulfato de pentosana para la resolucion de cicatrices en enfermedades vasculares progresivas cronicas. Expired - Lifetime ES2115571T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/478,347 US5643892A (en) 1995-06-07 1995-06-07 Method of treating chronic progressive vascular diseases
PCT/US1996/008367 WO1996040158A1 (en) 1995-06-07 1996-06-03 Method of treating chronic progressive vascular diseases
BR9704114-9A BR9704114A (pt) 1995-06-07 1997-07-28 Processo de tratamento de doenças vasculares progressivas crÈnicas

Publications (2)

Publication Number Publication Date
ES2115571T1 ES2115571T1 (es) 1998-07-01
ES2115571T3 true ES2115571T3 (es) 2003-09-01

Family

ID=25664870

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96917917T Expired - Lifetime ES2115571T3 (es) 1995-06-07 1996-06-03 Uso de polisulfato de pentosana para la resolucion de cicatrices en enfermedades vasculares progresivas cronicas.

Country Status (14)

Country Link
US (1) US5643892A (es)
EP (1) EP0809505B1 (es)
AU (1) AU699012B2 (es)
BR (1) BR9704114A (es)
CA (1) CA2210351C (es)
DE (1) DE809505T1 (es)
ES (1) ES2115571T3 (es)
HU (1) HUP9802431A3 (es)
IL (1) IL121217A (es)
NO (1) NO313686B1 (es)
NZ (1) NZ309991A (es)
TW (1) TW434018B (es)
WO (1) WO1996040158A1 (es)
ZA (1) ZA964247B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010005720A1 (en) * 1995-06-07 2001-06-28 U.S.A. As Represented By The Secretary Department Of Health And Human Services Method of treating chronic progressive vascular scarring diseases
US6255295B1 (en) 1996-12-23 2001-07-03 Nutramax Laboratories, Inc. Aminosugar, glycosaminoglycan or glycosaminoglycan-like compounds, and s-adenosylmethionine composition for the protection, treatment, repair, and reduction of inflammation of connective tissue
UA65587C2 (en) 1997-10-09 2004-04-15 Baker Norton Pharma Method for preventing nephrotoxicity induced by cyclosporins or tacrolimus
DE19747195A1 (de) * 1997-10-24 1999-04-29 Knoll Ag Verwendung von Glykosaminoglykanen zur Herstellung von pharmazeutischen Zubereitungen zur Behandlung von mit Diabetes assoziierten Augenkrankheiten
US20020010140A1 (en) 2000-01-19 2002-01-24 Striker Gary E. Use of pentosan polysulfate to treat certain conditions of the prostate
US20080214480A1 (en) * 2005-07-22 2008-09-04 Trf Pharma, Inc. Method for Treating Sickle Cell Disease and Sickle Cell Disease Sequalae
NZ571537A (en) * 2006-04-03 2012-06-29 Nutramax Lab Inc Stabilized pentosan polysulfate (PPS) formulations and methods of analayzing them
JP5604417B2 (ja) 2009-03-11 2014-10-08 ゼライス株式会社 アテローム性動脈硬化症の進行抑制薬・予防薬・血中コレステロール低下薬・機能性食品・特定保健用食品
US8871741B2 (en) * 2010-01-15 2014-10-28 Icahn School Of Medicine At Mount Sinai Inhibition of TNF-α induced activation of NFKB by pentosan polysulfate
JP6175431B2 (ja) 2011-06-20 2017-08-02 アイカーン スクール オブ メディシン アット マウント サイナイ ムコ多糖症およびその他のリソソーム障害に対する抗ｔｎｆ療法
US20130273096A1 (en) * 2011-10-05 2013-10-17 Bruce A. Daniels Therapeutic Sulfated Polysaccharides, Compositions Thereof, and Methods for Treating Patients
JP6935960B2 (ja) 2018-08-20 2021-09-15 株式会社レクメド 新規ポリ硫酸ペントサンナトリウム製剤

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4820693A (en) * 1986-05-22 1989-04-11 Angiogenics, Ltd. Method and composition for arresting angiogenesis and capillary, cell or membrane leakage
US4966890A (en) * 1986-04-04 1990-10-30 Angiogenics, Ltd. Method and composition for arresting angiogenesis and capillary, cell or membrane leakage
DE3725554A1 (de) * 1987-08-01 1989-02-09 Hoechst Ag Pharmazeutisches kombinationspraeparat sowie dessen herstellung und verwendung
US5032679A (en) * 1988-12-15 1991-07-16 Glycomed, Inc. Heparin fragments as inhibitors of smooth muscle cell proliferation
EP0466315A3 (en) * 1990-05-30 1992-07-01 Larrian Gillespie Compositions containing xylan sulphates for affecting growth factor function and for inhibiting fibroblast proliferation
US5605938A (en) * 1991-05-31 1997-02-25 Gliatech, Inc. Methods and compositions for inhibition of cell invasion and fibrosis using dextran sulfate

Also Published As

Publication number Publication date
HUP9802431A3 (en) 2001-06-28
BR9704114A (pt) 2000-06-06
DE809505T1 (de) 1998-05-28
US5643892A (en) 1997-07-01
ES2115571T1 (es) 1998-07-01
CA2210351A1 (en) 1996-12-19
IL121217A0 (en) 1999-10-28
AU6030096A (en) 1996-12-30
CA2210351C (en) 2003-09-23
NZ309991A (en) 2001-03-30
NO973081L (no) 1997-08-27
AU699012B2 (en) 1998-11-19
IL121217A (en) 2000-09-28
TW434018B (en) 2001-05-16
NO313686B1 (no) 2002-11-18
EP0809505B1 (en) 2003-04-02
ZA964247B (en) 1996-12-04
EP0809505A1 (en) 1997-12-03
HUP9802431A2 (hu) 1999-02-01
NO973081D0 (no) 1997-07-02
WO1996040158A1 (en) 1996-12-19
EP0809505A4 (en) 1998-07-01

Similar Documents

Publication Publication Date Title
ES2186737T3 (es) Composiciones de oxicodona de liberacion controlada.
ES2188782T3 (es) Formulaciones farmaceuticas que contienen darifenacina.
ES2052717T3 (es) Uso de derivados de indolona para la preparacion de medicamentos para el tratamiento de la enfermedad de parkinson.
ES2160693T3 (es) Formulacion estable de 10-hidroxi-7-etil-camptotecina en la forma lactona.
ES2170069T3 (es) 1-alfa-hidroxiprevitamina d para administracion oral.
RU94046316A (ru) Применение высокоэффективных фосфонатов при изготовлении лекарственных средств для лечения остеопороза
ES2093735T3 (es) Derivados de melatonina para uso en la terapia de trastornos del sueño y en medicacion preanestesica.
ES2084579T3 (es) Uso de buspirona en la preparacion de una composicion farmaceutica para el tratamiento del abuso del alcohol.
ES2115571T3 (es) Uso de polisulfato de pentosana para la resolucion de cicatrices en enfermedades vasculares progresivas cronicas.
ES2153906T3 (es) Uso de incienso para el tratamiento de la enfermedad de alzheimer.
GB2285219A (en) Use of norastemizole for the treatment of allergic disorders
AR036312A1 (es) Composicion farmaceutica
MX9205568A (es) Composicion farmaceutica que contiene cantidades de 5-amino-1beta-d-ribofuranosil-imidazol-4-carboxamida.
IT1244636B (it) Uso dell'acetil l-carnitina nel trattamento terapeutico del coma e composizioni farmaceutiche utili in tale trattamento.
ES2119748T3 (es) Composicion farmaceutica que contiene un farmaco ligeramente soluble en agua.
CO4230093A1 (es) Derivados del indol y sus usos medicos
MY124465A (en) Reduction of infarct volume using citicoline
AR087240A2 (es) Composiciones farmaceuticas que tienen epinastina y pseudoefedrina
KR890006227A (ko) 페놀-함유 진해성 액체 조성물
AR008559A1 (es) Uso de pentosanpolisulfato (pps) o de una sal farmaceuticamente aceptable del mismo
AR006202A1 (es) Usos de antagonista ige para preparar un medicamento util para el tratamiento de las enfermedades alergicas y composiciones que los contiene
KR890012942A (ko) 5-치환된 오르니틴 유도체
KR970005283A (ko) 심근경색발생 후의 환자를 처치하기 위한 서트랄린의 용도
BR9509433A (pt) Uso de (r-(z))-a-(metaxoiimino)-a-(1-azabiciclo-(2,2,2)oct-3-il)acetonitrila ou um sal farmaceuticamente aceitável da mesma processo para aperfeiçoar o processamento de uma proteina precursora de amilóide ao longo de um percurso não amiloidogênio processo para tratamento ou profilaxia do mal de alzheimer composição farmacêutica e uso processo ou composição
AR025549A1 (es) Mofetil micofelonato en asociacion con peg-ifn-alfa