ES2115571T1 - Metodo de tratar enfermedades vasculares progresivas y cronicas. - Google Patents
Metodo de tratar enfermedades vasculares progresivas y cronicas.Info
- Publication number
- ES2115571T1 ES2115571T1 ES96917917T ES96917917T ES2115571T1 ES 2115571 T1 ES2115571 T1 ES 2115571T1 ES 96917917 T ES96917917 T ES 96917917T ES 96917917 T ES96917917 T ES 96917917T ES 2115571 T1 ES2115571 T1 ES 2115571T1
- Authority
- ES
- Spain
- Prior art keywords
- pps
- vascular diseases
- chronic vascular
- treating progressive
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000001684 chronic effect Effects 0.000 title abstract 2
- 230000000750 progressive effect Effects 0.000 title abstract 2
- 208000019553 vascular disease Diseases 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 206010016654 Fibrosis Diseases 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000004761 fibrosis Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
LA INVENCION SE REFIERE A UN METODO PARA EL TRATAMIENTO DE UN PACIENTE MAMIFERO QUE SUFRE UNA ENFERMEDAD VASCULAR PROGRESIVA CRONICA (CPVD) CARACTERIZADA POR CICATRIZACION Y/O FIBROSIS CON EL FIN DE DETENER EL PROGRESO DE LA ENFERMEDAD Y RESOLVER LAS LESIONES DE CICATRIZACION O FIBROTICAS YA FORMADAS. EL METODO CONSISTE EN ADMINISTRAR AL PACIENTE UNA COMPOSICION FARMACEUTICA QUE CONTIENE UNA CANTIDAD EFICAZ DE POLISULFATO DE PENTOSANO (PPS) O UNA SAL FARMACEUTICAMENTE ACEPTABLE DEL MISMO. SE PREFIERE LA VIA ORAL DE ADMINISTRACION, CON DOSIS DIARIAS TOTALES DE PPS O DE SAL DE PPS DE ENTRE APROXIMADAMENTE 50 Y 1200 MG POR DIA.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/478,347 US5643892A (en) | 1995-06-07 | 1995-06-07 | Method of treating chronic progressive vascular diseases |
PCT/US1996/008367 WO1996040158A1 (en) | 1995-06-07 | 1996-06-03 | Method of treating chronic progressive vascular diseases |
BR9704114-9A BR9704114A (pt) | 1995-06-07 | 1997-07-28 | Processo de tratamento de doenças vasculares progressivas crÈnicas |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2115571T1 true ES2115571T1 (es) | 1998-07-01 |
ES2115571T3 ES2115571T3 (es) | 2003-09-01 |
Family
ID=25664870
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96917917T Expired - Lifetime ES2115571T3 (es) | 1995-06-07 | 1996-06-03 | Uso de polisulfato de pentosana para la resolucion de cicatrices en enfermedades vasculares progresivas cronicas. |
Country Status (14)
Country | Link |
---|---|
US (1) | US5643892A (es) |
EP (1) | EP0809505B1 (es) |
AU (1) | AU699012B2 (es) |
BR (1) | BR9704114A (es) |
CA (1) | CA2210351C (es) |
DE (1) | DE809505T1 (es) |
ES (1) | ES2115571T3 (es) |
HU (1) | HUP9802431A3 (es) |
IL (1) | IL121217A (es) |
NO (1) | NO313686B1 (es) |
NZ (1) | NZ309991A (es) |
TW (1) | TW434018B (es) |
WO (1) | WO1996040158A1 (es) |
ZA (1) | ZA964247B (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20010005720A1 (en) * | 1995-06-07 | 2001-06-28 | U.S.A. As Represented By The Secretary Department Of Health And Human Services | Method of treating chronic progressive vascular scarring diseases |
US6255295B1 (en) | 1996-12-23 | 2001-07-03 | Nutramax Laboratories, Inc. | Aminosugar, glycosaminoglycan or glycosaminoglycan-like compounds, and s-adenosylmethionine composition for the protection, treatment, repair, and reduction of inflammation of connective tissue |
UA65587C2 (en) | 1997-10-09 | 2004-04-15 | Baker Norton Pharma | Method for preventing nephrotoxicity induced by cyclosporins or tacrolimus |
DE19747195A1 (de) * | 1997-10-24 | 1999-04-29 | Knoll Ag | Verwendung von Glykosaminoglykanen zur Herstellung von pharmazeutischen Zubereitungen zur Behandlung von mit Diabetes assoziierten Augenkrankheiten |
WO2001052867A1 (en) * | 2000-01-19 | 2001-07-26 | The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Use of pentosan polysulfate to treat certain conditions of the prostate |
WO2007014155A2 (en) * | 2005-07-22 | 2007-02-01 | Trf Pharma, Inc. | Method for treating sickle cell disease and sickle cell disease sequelae |
DK2010220T3 (da) * | 2006-04-03 | 2022-05-23 | Ceva Animal Health Pty Ltd | Stabiliserede pentosanpolysulfat-(pps)-formuleringer |
EP2407174B1 (en) | 2009-03-11 | 2014-05-07 | Jellice Co., Ltd. | Progression inhibitor or prophylactic agent for atherosclerosis, blood cholesterol level-lowering agent, and functional food or food for specified health uses |
WO2011088418A2 (en) * | 2010-01-15 | 2011-07-21 | Mount Sinai School Of Medicine | Inhibition of tnf-alpha induced activation of nfkb by pentosan polysulfate |
JP6175431B2 (ja) | 2011-06-20 | 2017-08-02 | アイカーン スクール オブ メディシン アット マウント サイナイ | ムコ多糖症およびその他のリソソーム障害に対する抗tnf療法 |
US20130273096A1 (en) * | 2011-10-05 | 2013-10-17 | Bruce A. Daniels | Therapeutic Sulfated Polysaccharides, Compositions Thereof, and Methods for Treating Patients |
AU2018437600B2 (en) | 2018-08-20 | 2022-11-17 | Reqmed Company, Ltd. | Novel pentosan polysulfate sodium preparation |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4820693A (en) * | 1986-05-22 | 1989-04-11 | Angiogenics, Ltd. | Method and composition for arresting angiogenesis and capillary, cell or membrane leakage |
US4966890A (en) * | 1986-04-04 | 1990-10-30 | Angiogenics, Ltd. | Method and composition for arresting angiogenesis and capillary, cell or membrane leakage |
DE3725554A1 (de) * | 1987-08-01 | 1989-02-09 | Hoechst Ag | Pharmazeutisches kombinationspraeparat sowie dessen herstellung und verwendung |
US5032679A (en) * | 1988-12-15 | 1991-07-16 | Glycomed, Inc. | Heparin fragments as inhibitors of smooth muscle cell proliferation |
EP0466315A3 (en) * | 1990-05-30 | 1992-07-01 | Larrian Gillespie | Compositions containing xylan sulphates for affecting growth factor function and for inhibiting fibroblast proliferation |
US5605938A (en) * | 1991-05-31 | 1997-02-25 | Gliatech, Inc. | Methods and compositions for inhibition of cell invasion and fibrosis using dextran sulfate |
-
1995
- 1995-06-07 US US08/478,347 patent/US5643892A/en not_active Expired - Fee Related
-
1996
- 1996-05-27 ZA ZA964247A patent/ZA964247B/xx unknown
- 1996-06-03 EP EP96917917A patent/EP0809505B1/en not_active Expired - Lifetime
- 1996-06-03 IL IL12121796A patent/IL121217A/xx not_active IP Right Cessation
- 1996-06-03 HU HU9802431A patent/HUP9802431A3/hu unknown
- 1996-06-03 NZ NZ309991A patent/NZ309991A/en unknown
- 1996-06-03 DE DE0809505T patent/DE809505T1/de active Pending
- 1996-06-03 AU AU60300/96A patent/AU699012B2/en not_active Ceased
- 1996-06-03 WO PCT/US1996/008367 patent/WO1996040158A1/en active IP Right Grant
- 1996-06-03 ES ES96917917T patent/ES2115571T3/es not_active Expired - Lifetime
- 1996-06-03 CA CA002210351A patent/CA2210351C/en not_active Expired - Fee Related
- 1996-08-03 TW TW085109390A patent/TW434018B/zh not_active IP Right Cessation
-
1997
- 1997-07-02 NO NO19973081A patent/NO313686B1/no unknown
- 1997-07-28 BR BR9704114-9A patent/BR9704114A/pt not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO1996040158A1 (en) | 1996-12-19 |
EP0809505A4 (en) | 1998-07-01 |
TW434018B (en) | 2001-05-16 |
AU6030096A (en) | 1996-12-30 |
NO313686B1 (no) | 2002-11-18 |
AU699012B2 (en) | 1998-11-19 |
EP0809505A1 (en) | 1997-12-03 |
ZA964247B (en) | 1996-12-04 |
HUP9802431A3 (en) | 2001-06-28 |
ES2115571T3 (es) | 2003-09-01 |
IL121217A (en) | 2000-09-28 |
NO973081D0 (no) | 1997-07-02 |
BR9704114A (pt) | 2000-06-06 |
NZ309991A (en) | 2001-03-30 |
IL121217A0 (en) | 1999-10-28 |
NO973081L (no) | 1997-08-27 |
EP0809505B1 (en) | 2003-04-02 |
CA2210351A1 (en) | 1996-12-19 |
HUP9802431A2 (hu) | 1999-02-01 |
DE809505T1 (de) | 1998-05-28 |
CA2210351C (en) | 2003-09-23 |
US5643892A (en) | 1997-07-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US5801161A (en) | Pharmaceutical composition for the intranasal administration of hydroxocobalamin | |
RU94046316A (ru) | Применение высокоэффективных фосфонатов при изготовлении лекарственных средств для лечения остеопороза | |
EA200501496A1 (ru) | Высокоселективные ингибиторы обратного захвата норэпинефрина и способы их применения | |
ES2115571T1 (es) | Metodo de tratar enfermedades vasculares progresivas y cronicas. | |
ES2170069T3 (es) | 1-alfa-hidroxiprevitamina d para administracion oral. | |
IL124977A0 (en) | Oral administration of effective amounts of forms of hyaluronic acid | |
FR2798065B1 (fr) | Utilisation de la nicotine ou de ses derives dans un medicament pour le traitement des maladies neurologiques, notamment la maladie de parkinson | |
US4438138A (en) | Reduction of cholesterol with meta-chloro α-t-butylaminopropiophenone | |
CA2274510A1 (en) | Treatment of osteoarthritis by administering poly-n-acetyl-d-glucosamine | |
RU2003125274A (ru) | Применение флумазенила в производстве лекарства для лечения алкогольной зависимости | |
ECSP044986A (es) | Composicion farmaceutica que comprende lumiracoxib | |
US20070292535A1 (en) | Strontium compositions and methods of treating arthritic and or osteoporitic conditions | |
AR035946A1 (es) | Composiciones farmaceuticas estrogenicas para usar en el tratamiento de desordenes en mujeres perimenopausicas, menopausicas o posmenopausicas, y usos de dichas composiciones para la preparacion de medicamentos | |
US5925625A (en) | Pharmaceutical composition for the intranasal administration of hydroxocobalamin | |
BR9809396A (pt) | Método de tratamento de doenças de cicatrização vascular progressivas | |
AR006202A1 (es) | Usos de antagonista ige para preparar un medicamento util para el tratamiento de las enfermedades alergicas y composiciones que los contiene | |
RU2002129298A (ru) | Применение галантамина для лечения психоневрологического поведения, связанного с болезнью альцгеймера | |
KR970005283A (ko) | 심근경색발생 후의 환자를 처치하기 위한 서트랄린의 용도 | |
JP2022528481A (ja) | ピモジドとメトトレキサートの医薬組成物、及びその使用 | |
AR003957A1 (es) | Composicion farmaceutica para tratar un paciente mamifero que sufre una enfermedad vascular cronica progresiva (cpvd) | |
RU2160102C2 (ru) | Применение бензидамина для лечения патологических состояний, вызванных фно | |
AR032479A1 (es) | Nuevas composiciones farmaceuticas que contienen epinastina y pseudoefedrina | |
EP1518554B1 (en) | Pharmaceutical composition for the treatment of hyperhomocysteinemia | |
AR020167A1 (es) | Metodo para la prevencion del inicio del asma | |
Levin et al. | Therapeutic trials in acute gouty arthritis |