SK287331B6 - Liečivo na liečenie zápalových a obštrukčných ochorení dýchacích ciest - Google Patents

Liečivo na liečenie zápalových a obštrukčných ochorení dýchacích ciest Download PDF

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Publication number
SK287331B6
SK287331B6 SK650-2003A SK6502003A SK287331B6 SK 287331 B6 SK287331 B6 SK 287331B6 SK 6502003 A SK6502003 A SK 6502003A SK 287331 B6 SK287331 B6 SK 287331B6
Authority
SK
Slovakia
Prior art keywords
medicament according
parts
medicament
carbon atoms
dispersion
Prior art date
Application number
SK650-2003A
Other languages
English (en)
Slovak (sk)
Other versions
SK6502003A3 (en
Inventor
Bernard Cuenoud
Robin Alec Fairhurst
Nicholas Lowther
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of SK6502003A3 publication Critical patent/SK6502003A3/sk
Publication of SK287331B6 publication Critical patent/SK287331B6/sk

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/47042-Quinolinones, e.g. carbostyril
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/16Central respiratory analeptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
SK650-2003A 2000-12-04 2001-12-03 Liečivo na liečenie zápalových a obštrukčných ochorení dýchacích ciest SK287331B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0029562.6A GB0029562D0 (en) 2000-12-04 2000-12-04 Organic compounds
PCT/EP2001/014122 WO2002045703A2 (en) 2000-12-04 2001-12-03 Mixtures or organic compounds for the treatmentof airway diseases

Publications (2)

Publication Number Publication Date
SK6502003A3 SK6502003A3 (en) 2003-12-02
SK287331B6 true SK287331B6 (sk) 2010-07-07

Family

ID=9904414

Family Applications (1)

Application Number Title Priority Date Filing Date
SK650-2003A SK287331B6 (sk) 2000-12-04 2001-12-03 Liečivo na liečenie zápalových a obštrukčných ochorení dýchacích ciest

Country Status (28)

Country Link
US (5) US6800643B2 (hu)
EP (2) EP1772142A3 (hu)
JP (2) JP2004514739A (hu)
KR (1) KR100523541B1 (hu)
CN (1) CN1212119C (hu)
AT (1) ATE361077T1 (hu)
AU (2) AU1708202A (hu)
BR (1) BRPI0115910B8 (hu)
CA (1) CA2427282C (hu)
CY (1) CY1106727T1 (hu)
CZ (1) CZ304294B6 (hu)
DE (1) DE60128258T2 (hu)
DK (1) DK1341542T3 (hu)
EC (1) ECSP034620A (hu)
ES (1) ES2284732T3 (hu)
GB (1) GB0029562D0 (hu)
HK (1) HK1059564A1 (hu)
HU (1) HU229552B1 (hu)
IL (2) IL155709A0 (hu)
MX (1) MXPA03004976A (hu)
NO (1) NO325692B1 (hu)
NZ (1) NZ525731A (hu)
PL (1) PL204002B1 (hu)
PT (1) PT1341542E (hu)
RU (1) RU2292890C2 (hu)
SK (1) SK287331B6 (hu)
WO (1) WO2002045703A2 (hu)
ZA (1) ZA200303399B (hu)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
AR028948A1 (es) 2000-06-20 2003-05-28 Astrazeneca Ab Compuestos novedosos
GB0029562D0 (en) * 2000-12-04 2001-01-17 Novartis Ag Organic compounds
ES2425392T3 (es) 2002-03-20 2013-10-15 Mannkind Corporation Cartucho para un aparato de inhalación
US20040146509A1 (en) * 2002-07-25 2004-07-29 Zhihe Li Methods for improvement of lung function using TGF-beta inhibitors
PA8578101A1 (es) 2002-08-13 2004-05-07 Warner Lambert Co Derivados de heterobiarilo como inhibidores de metaloproteinasa de la matriz
US7250426B2 (en) * 2002-11-29 2007-07-31 Boehringer Ingelheim Pharma Gmbh & Co Kg Tiotropium-containing pharmaceutical combination for inhalation
PE20100399A1 (es) * 2003-04-02 2010-06-01 Novartis Ag Procedimiento para preparar oxi-(1h)-quinolin-2-onas 5-(alfa-haloacetil)-8-sustituidas
PT1613315E (pt) * 2003-04-04 2009-04-22 Novartis Ag Derivados da quinolina-2-ona para o tratamento de doenças das vias aéreas respiratórias
GB0307856D0 (en) * 2003-04-04 2003-05-14 Novartis Ag Organic compounds
GB0411056D0 (en) 2004-05-18 2004-06-23 Novartis Ag Organic compounds
ATE486064T1 (de) 2004-08-20 2010-11-15 Mannkind Corp Katalyse der diketopiperazinsynthese
PL1791542T3 (pl) 2004-08-23 2015-11-30 Mannkind Corp Sole diketopiperazyny do dostarczania leków
KR100666220B1 (ko) * 2005-01-31 2007-01-09 영남대학교 산학협력단 구내염 치료용 분사제 조성물
EP2484382A1 (en) * 2005-03-30 2012-08-08 Schering Corporation Medicament comprising a phosphodiesterase IV inhibitor in an inhalable form
GB0511065D0 (en) * 2005-05-31 2005-07-06 Novartis Ag Organic compounds
GB0511066D0 (en) * 2005-05-31 2005-07-06 Novartis Ag Organic compounds
TW200738634A (en) 2005-08-02 2007-10-16 Astrazeneca Ab New salt
TW200744612A (en) * 2005-08-26 2007-12-16 Astrazeneca Ab New combination
AU2006290870B2 (en) 2005-09-14 2013-02-28 Mannkind Corporation Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces
GB0523655D0 (en) * 2005-11-21 2005-12-28 Novartis Ag Organic compounds
GB0523656D0 (en) * 2005-11-21 2005-12-28 Novartis Ag Organic compounds
WO2007075800A2 (en) * 2005-12-20 2007-07-05 Tika Läkemedel Ab Methods and systems for the delivery of corticosteroids
EP2497484A3 (en) 2006-02-22 2012-11-07 MannKind Corporation A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent
US20070225233A1 (en) * 2006-03-27 2007-09-27 Tsu-Fuh Yeh Reducing the risk of chronic lung disease in infants
EP1878722A1 (en) * 2006-07-13 2008-01-16 Novartis AG Quinolinone derivatives and their pharmaceutical compositions
BRPI0713951B8 (pt) * 2006-06-30 2021-05-25 Novartis Ag derivados de quinazolina, e composição farmacêutica
ES2394589T3 (es) 2007-12-14 2013-02-04 Aerodesigns, Inc Suministro de productos alimenticios transformables en aerosol
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
DK2570147T3 (da) 2008-06-13 2018-01-29 Mannkind Corp Tørpulverinhalator og system til lægemiddelindgivelse
KR101628410B1 (ko) 2008-06-20 2016-06-08 맨카인드 코포레이션 흡입 활동에 관한 실시간 프로파일링을 위한 대화형 장치 및 방법
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
CA2754595C (en) 2009-03-11 2017-06-27 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
US9463161B2 (en) 2009-05-29 2016-10-11 Pearl Therapeutics, Inc. Compositions for pulmonary delivery of long-acting muscarinic antagonists and associated methods and systems
US8734845B2 (en) 2009-06-12 2014-05-27 Mannkind Corporation Diketopiperazine microparticles with defined specific surface areas
KR100940388B1 (ko) * 2009-07-01 2010-02-02 유병덕 스크류탈수기 및 이를 포함하는 유기성폐기물 건조장치
CA2778698A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
RU2531455C2 (ru) 2010-06-21 2014-10-20 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
CA2805700A1 (en) * 2010-07-16 2012-01-19 Cipla Limited Pharmaceutical compositions comprising r(+) budesonide and formoterol
BR112013008974A2 (pt) * 2010-10-12 2023-12-19 Cipla Ltd Composição farmacêutica, processo para fabricar uma composição farmacêutica e uso de uma composição farmacêutica
MY180552A (en) 2011-04-01 2020-12-02 Mannkind Corp Blister package for pharmaceutical cartridges
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
CN102247380A (zh) * 2011-08-19 2011-11-23 北京阜康仁生物制药科技有限公司 一种以布地奈德与茚达特罗为活性成分的复方制剂
WO2013063160A1 (en) 2011-10-24 2013-05-02 Mannkind Corporation Methods and compositions for treating pain
WO2013132514A2 (en) * 2012-03-09 2013-09-12 Rao Davuluri Ramamohan A novel process for the preparation of (r)-5-[2-[(5, 6-diethyl-2, 3-dihydro-1h-inden-2-yl) amino]-1-hydroxyethyl]-8-hydroxy quinolin-2(1h)-one
WO2014008639A1 (zh) * 2012-07-11 2014-01-16 上海威智医药科技有限公司 制备茚达特罗的方法
CA2878457C (en) 2012-07-12 2021-01-19 Mannkind Corporation Dry powder drug delivery systems and methods
WO2014044288A1 (en) * 2012-09-21 2014-03-27 Crystal Pharma Sa Methods for the preparation of indacaterol and pharmaceutically acceptable salts thereof
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
BR112015023168B1 (pt) 2013-03-15 2021-08-10 Mannkind Corporation Composição de 3,6-bis(n-fumaril-4-aminobutil)-2,5-dicetopiperazina cristalina, método de produção de partículas de 3,6-bis(n-fumaril-4-aminobutil)-2,5-dicetopiperazina e uso de uma composição de dicetopiperazina cristalina
CN114848614A (zh) 2013-07-18 2022-08-05 曼金德公司 热稳定性干粉药物组合物和方法
CA2920488C (en) 2013-08-05 2022-04-26 Mannkind Corporation Insufflation apparatus and methods
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
ITUB20153978A1 (it) * 2015-09-28 2017-03-28 Laboratorio Chimico Int S P A Procedimento per la preparazione di derivati di indanammina e di nuovi intermedi di sintesi.
CN107868045A (zh) * 2016-09-28 2018-04-03 四川海思科制药有限公司 一种茚达特罗中间体的制备方法
CN106831445B (zh) * 2016-11-22 2019-01-22 斯芬克司药物研发(天津)股份有限公司 一种茚基胺化合物的制备方法
CN110229078A (zh) * 2019-05-22 2019-09-13 博诺康源(北京)药业科技有限公司 一种茚达特罗起始原料开环杂质的制备
CN114751857A (zh) * 2022-04-29 2022-07-15 梯尔希(南京)药物研发有限公司 一种茚达特罗杂质的制备方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4607028A (en) * 1983-08-18 1986-08-19 Ciba-Geigy Corporation Novel carboxylic acid esters
WO1993018007A1 (en) * 1992-03-13 1993-09-16 Tokyo Tanabe Company Limited Novel carbostyril derivative
GB9405019D0 (en) 1994-03-15 1994-04-27 Smithkline Beecham Plc Novel compounds
GB9501286D0 (en) 1995-01-24 1995-03-15 Ciba Geigy Ag Pharmaceutical compositions and preparations thereof
EP0761216B1 (en) * 1995-08-16 2003-11-12 Huntington Medical Research Institutes Rhodamine 123 compositions for treating prostate cancer
GB9603237D0 (en) 1996-02-16 1996-04-17 Sandoz Ltd Organic compounds
TW375604B (en) 1996-02-19 1999-12-01 Kissei Pharmaceutical 3,4-di-substituting phenyl-ethanolamine-tetrahydronaphthyl carboxylic amide derivatives
GB9610122D0 (en) * 1996-05-15 1996-07-24 Reckitt & Colmann Prod Ltd Organic compositions
AU735249B2 (en) * 1997-07-03 2001-07-05 Asahi Kasei Kabushiki Kaisha Novel tricyclic compounds having saturated rings and medicinal compositions containing the same
GB9902689D0 (en) * 1999-02-08 1999-03-31 Novartis Ag Organic compounds
GB9913083D0 (en) * 1999-06-04 1999-08-04 Novartis Ag Organic compounds
US6448239B1 (en) 1999-06-03 2002-09-10 Trustees Of Princeton University Peroxynitrite decomposition catalysts and methods of use thereof
US6664235B1 (en) * 1999-08-20 2003-12-16 Riken Medicaments comprising sialic acid derivatives as active ingredients
CA2417973A1 (en) * 2000-08-04 2002-02-14 Longwood Pharmaceutical Research, Inc. Formulations of mometasone and a bronchodilator for pulmonary administration
GB0029562D0 (en) * 2000-12-04 2001-01-17 Novartis Ag Organic compounds

Also Published As

Publication number Publication date
KR20030048065A (ko) 2003-06-18
NO20032510L (no) 2003-06-03
CZ20031537A3 (cs) 2003-10-15
KR100523541B1 (ko) 2005-10-25
WO2002045703A2 (en) 2002-06-13
EP1772142A2 (en) 2007-04-11
US20120108555A1 (en) 2012-05-03
MXPA03004976A (es) 2003-09-05
IL155709A0 (en) 2003-11-23
NO20032510D0 (no) 2003-06-03
NZ525731A (en) 2004-11-26
EP1772142A3 (en) 2011-09-14
CZ304294B6 (cs) 2014-02-19
GB0029562D0 (en) 2001-01-17
BR0115910A (pt) 2004-01-20
HUP0302571A3 (en) 2005-05-30
US20040038951A1 (en) 2004-02-26
ES2284732T3 (es) 2007-11-16
SK6502003A3 (en) 2003-12-02
US20100068288A1 (en) 2010-03-18
CN1212119C (zh) 2005-07-27
BRPI0115910B8 (pt) 2021-05-25
US7008951B2 (en) 2006-03-07
RU2003119549A (ru) 2005-02-10
HK1059564A1 (en) 2004-07-09
US6800643B2 (en) 2004-10-05
DK1341542T3 (da) 2007-09-03
DE60128258D1 (de) 2007-06-14
BRPI0115910B1 (pt) 2019-12-31
PL362443A1 (en) 2004-11-02
NO325692B1 (no) 2008-07-07
US7622484B2 (en) 2009-11-24
DE60128258T2 (de) 2007-12-27
CY1106727T1 (el) 2012-05-23
EP1341542B1 (en) 2007-05-02
IL155709A (en) 2008-11-26
EP1341542A2 (en) 2003-09-10
AU2002217082B2 (en) 2005-04-07
HUP0302571A2 (hu) 2003-11-28
JP2004514739A (ja) 2004-05-20
CA2427282A1 (en) 2002-06-13
RU2292890C2 (ru) 2007-02-10
AU1708202A (en) 2002-06-18
WO2002045703A3 (en) 2003-03-13
ATE361077T1 (de) 2007-05-15
HU229552B1 (en) 2014-01-28
ZA200303399B (en) 2004-04-23
US20060052352A1 (en) 2006-03-09
PT1341542E (pt) 2007-08-01
US20050009795A1 (en) 2005-01-13
CN1477963A (zh) 2004-02-25
CA2427282C (en) 2010-10-19
JP2007302684A (ja) 2007-11-22
ECSP034620A (es) 2003-06-25
PL204002B1 (pl) 2009-12-31

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Expiry date: 20211203