KR890009400A - 다이클로닌 Hcl및 페놀을 함유하는 약제학적 조성물 - Google Patents

다이클로닌 Hcl및 페놀을 함유하는 약제학적 조성물 Download PDF

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Publication number
KR890009400A
KR890009400A KR1019880016639A KR880016639A KR890009400A KR 890009400 A KR890009400 A KR 890009400A KR 1019880016639 A KR1019880016639 A KR 1019880016639A KR 880016639 A KR880016639 A KR 880016639A KR 890009400 A KR890009400 A KR 890009400A
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KR
South Korea
Prior art keywords
phenol
diclonin
hci
matter
pharmaceutical composition
Prior art date
Application number
KR1019880016639A
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English (en)
Inventor
소렌티노 제임스-빈센트
조셉 켈레이 윌리암
올로레모이에 진
Original Assignee
원본미기재
리챠드슨 빅스 인코포레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 원본미기재, 리챠드슨 빅스 인코포레이티드 filed Critical 원본미기재
Publication of KR890009400A publication Critical patent/KR890009400A/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

내용 없음

Description

디아클로닌 Hcl및 페놀을 함유하는 약제학적 조성물
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (6)

  1. 약 0.02 내지 약 3.0W/W의 다이클로닌 HCI및 약 0.3 내지 약 5.0W/W%의 페놀을 약제학적으로 허용되는 담체와의 혼합물 형태로 함유함을 특징으로하는, 강화된 항미생물적 작용을 갖는 물질의 약제학적 조성물.
  2. 약 0.05 내지 약 2.0W/V%의 다이클로닌 HCI 및 약 0,5 내지 약 3.0W/V%의 페놀이 혼입된 수성 기본의 구강적으로 허용되는 약제학적 담체를 함유하며 PH가 약 3 내지 4임을 특징으로 하는, 구강 건강 보호 용도 및 강화된 항미생물적 작용을 갖는 물질의 액체 약제학적 조성물.
  3. 제 2 항에 있어서, pH가 약 3.2 내지 약 3.6인 조성물.
  4. 약 0.1W/V%의 다이클로닌 HCI 및 약 1.0 내지 1.4W/V%의 페놀이 혼입된 수성-기본의 구강적으로 허용되는 약제학적 담체를 함유하며 pH거 약 3.4임을 특징으로 하는, 구강 건강 보호 용도 및 강화된 항미생물적 작용을 갖는 물질의 액체 약제학적 조성물.
  5. 약 1 내지 약 3mg의 다이클로닌 HCI 및 약 10 내지 약 50mg의 페놀을 함유함을 특징으로 하는 로젠지.
  6. 제 5 항에 있어서, 페놀 약 20 내지 약 35mg을 함유하는 로젠지.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019880016639A 1987-12-16 1988-12-14 다이클로닌 Hcl및 페놀을 함유하는 약제학적 조성물 KR890009400A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/133,834 US4808410A (en) 1987-12-16 1987-12-16 Pharmaceutical compositions containing dyclonine HC1 and phenol
US07/133,834 1987-12-16

Publications (1)

Publication Number Publication Date
KR890009400A true KR890009400A (ko) 1989-08-01

Family

ID=22460497

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019880016639A KR890009400A (ko) 1987-12-16 1988-12-14 다이클로닌 Hcl및 페놀을 함유하는 약제학적 조성물

Country Status (11)

Country Link
US (1) US4808410A (ko)
EP (1) EP0321231B1 (ko)
JP (1) JPH01265026A (ko)
KR (1) KR890009400A (ko)
AT (1) ATE73329T1 (ko)
AU (1) AU629803B2 (ko)
CA (1) CA1318599C (ko)
DE (1) DE3869088D1 (ko)
DK (1) DK701188A (ko)
NZ (1) NZ227339A (ko)
PH (1) PH24860A (ko)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4892877A (en) * 1987-10-27 1990-01-09 Richardson-Vicks Inc. Antitussive liquid compositions containing phenol
US4917894A (en) * 1988-06-29 1990-04-17 Beecham Inc. Rapid-onset long-duration oral anesthetic composition
AR245888A1 (es) * 1989-01-23 1994-03-30 Merrell Pharma Inc Procedimiento para la preparacion de una composicion farmaceutica liquida de derivados de piperidinoalcanol.
US4931473A (en) * 1989-02-15 1990-06-05 Richardson-Vicks Inc. Anesthetic oral compositions
US5100898A (en) * 1990-01-25 1992-03-31 Richardson-Vicks Inc. Antitussive liquid compositions containing dyclonine
US5478565A (en) * 1990-03-27 1995-12-26 Warner-Lambert Company Treatment of sinus headache
US5547657A (en) * 1994-10-11 1996-08-20 Eastman Chemical Company Low-irritation anesthetic and antiseptic mouth rinse
US5641512A (en) * 1995-03-29 1997-06-24 The Procter & Gamble Company Soft gelatin capsule compositions
US10179159B2 (en) 1999-10-22 2019-01-15 Scott Wepfer Topical anesthetic formulation
AU5286901A (en) * 1999-10-22 2001-06-18 Transdermatech, Inc. Topical anesthetic formulation
US7144846B2 (en) * 2004-05-11 2006-12-05 Steris, Inc. Acidic phenolic disinfectant compositions
US9789101B2 (en) * 2010-03-30 2017-10-17 Helperby Therapeutics Limited Methods and compositions for treating microbial infection using pyrroloquinone

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2868689A (en) * 1956-10-09 1959-01-13 Allied Lab Inc Pharmaceutical preparations containing dyclonine hydrochloride and chlorobutanol
US3203097A (en) * 1963-04-25 1965-08-31 Denver Chemical Mfg Company Germicidal dental pad
US4067997A (en) * 1975-05-21 1978-01-10 Med-Chem Laboratories Synergistic microbecidal composition and method
US4139627A (en) * 1977-10-06 1979-02-13 Beecham Inc. Anesthetic lozenges
DE2860482D1 (en) * 1977-11-07 1981-03-26 Beecham Inc Anaesthetic lozenges and method of preparing them
JPS5549317A (en) * 1978-10-02 1980-04-09 Dow Chemical Co Control of virus surrounded with phenylketones
US4624849A (en) * 1984-11-02 1986-11-25 The Procter & Gamble Company Antimicrobial lozenges
US4713243A (en) * 1986-06-16 1987-12-15 Johnson & Johnson Products, Inc. Bioadhesive extruded film for intra-oral drug delivery and process

Also Published As

Publication number Publication date
PH24860A (en) 1990-12-26
EP0321231A1 (en) 1989-06-21
AU629803B2 (en) 1992-10-15
EP0321231B1 (en) 1992-03-11
DE3869088D1 (de) 1992-04-16
AU2700488A (en) 1989-06-22
DK701188D0 (da) 1988-12-16
JPH01265026A (ja) 1989-10-23
NZ227339A (en) 1990-09-26
US4808410A (en) 1989-02-28
ATE73329T1 (de) 1992-03-15
DK701188A (da) 1989-06-17
CA1318599C (en) 1993-06-01

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