BG62229B2 - Моноклонални антитела срещу човешки туморнекротизиращ фактор и използването им - Google Patents
Моноклонални антитела срещу човешки туморнекротизиращ фактор и използването им Download PDFInfo
- Publication number
- BG62229B2 BG62229B2 BG098602A BG9860294A BG62229B2 BG 62229 B2 BG62229 B2 BG 62229B2 BG 098602 A BG098602 A BG 098602A BG 9860294 A BG9860294 A BG 9860294A BG 62229 B2 BG62229 B2 BG 62229B2
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- Prior art keywords
- tnf
- antibodies
- monoclonal antibodies
- cells
- tak
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/241—Tumor Necrosis Factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19863631229 DE3631229A1 (de) | 1986-09-13 | 1986-09-13 | Monoklonale antikoerper gegen humanen tumornekrosefaktor (tnf) und deren verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG62229B2 true BG62229B2 (bg) | 1999-05-31 |
Family
ID=6309540
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG098602A BG62229B2 (bg) | 1986-09-13 | 1994-02-28 | Моноклонални антитела срещу човешки туморнекротизиращ фактор и използването им |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5231024A (pt) |
| EP (1) | EP0260610B1 (pt) |
| JP (2) | JP2837160B2 (pt) |
| BG (1) | BG62229B2 (pt) |
| BR (1) | BR1100843A (pt) |
| CA (1) | CA1337717C (pt) |
| DE (2) | DE3631229A1 (pt) |
| DK (1) | DK473887A (pt) |
| ES (1) | ES2058083T3 (pt) |
| FI (1) | FI91421C (pt) |
| ZA (1) | ZA876807B (pt) |
Families Citing this family (174)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6419927B1 (en) | 1981-09-08 | 2002-07-16 | Anthony Cerami | Method for reducing adverse effects of a human 70kDa mediator which results from endotoxin stimulation of macrophages |
| US5700466A (en) * | 1981-09-08 | 1997-12-23 | The Rockefeller University | Method of ameliorating or preventing septic shock using a monoclonal antibody specific to cachectin/tumor necrosis factor |
| US6309640B1 (en) | 1981-09-08 | 2001-10-30 | The Rockefeller University | Lipoprotein lipase suppression by endotoxin-induced mediator (shock assay) |
| GB2233559B (en) * | 1988-03-11 | 1992-03-04 | Celltech Ltd | Antibodies for use in antilymphocyte antibody therapy |
| DE3823804A1 (de) * | 1988-07-14 | 1990-01-18 | Basf Ag | Neutralisation der in vitro und in vivo toxischen eigenschaften von tnf-(alpha) durch monoklonale antikoerper und den davon abgeleiteten fragmenten |
| NZ229922A (en) * | 1988-07-18 | 1992-04-28 | Chiron Corp | Monoclonal antibodies specifically binding cachectin (tumor necrosis factor) and compositions |
| AU4182289A (en) * | 1988-08-19 | 1990-03-23 | Celltech Limited | Pharmaceutical products for anti-neoplastic therapy |
| WO1991002078A1 (en) | 1989-08-07 | 1991-02-21 | Peptide Technology Ltd | Tumour necrosis factor binding ligands |
| US20030225254A1 (en) * | 1989-08-07 | 2003-12-04 | Rathjen Deborah Ann | Tumour necrosis factor binding ligands |
| US5959087A (en) * | 1989-08-07 | 1999-09-28 | Peptide Technology, Ltd. | Tumour necrosis factor binding ligands |
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Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0780914B2 (ja) * | 1984-04-02 | 1995-08-30 | 旭化成工業株式会社 | ヒト腫瘍壊死因子に対する抗体 |
| JPS60209528A (ja) * | 1984-04-03 | 1985-10-22 | Asahi Chem Ind Co Ltd | ヒト腫瘍壊死因子の精製方法 |
| JPS6163698A (ja) * | 1984-09-05 | 1986-04-01 | Asahi Chem Ind Co Ltd | 生理活性物質に対するモノクロ−ナル抗体とそれを用いる生理活性物質の精製方法 |
| IL73883A (en) * | 1984-12-20 | 1990-12-23 | Yeda Res & Dev | Monoclonal antibodies against tnf-alpha,hybridomas producing them and method for the purification of tnf-alpha |
| US4870163A (en) * | 1985-08-29 | 1989-09-26 | New York Blood Center, Inc. | Preparation of pure human tumor necrosis factor and hybridomas producing monoclonal antibodies to human tumor necrosis factor |
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1986
- 1986-09-13 DE DE19863631229 patent/DE3631229A1/de not_active Withdrawn
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1987
- 1987-09-08 US US07/094,289 patent/US5231024A/en not_active Expired - Fee Related
- 1987-09-11 DK DK473887A patent/DK473887A/da not_active Application Discontinuation
- 1987-09-11 FI FI873948A patent/FI91421C/fi not_active IP Right Cessation
- 1987-09-11 EP EP87113278A patent/EP0260610B1/de not_active Expired - Lifetime
- 1987-09-11 DE DE87113278T patent/DE3787241D1/de not_active Expired - Fee Related
- 1987-09-11 ES ES87113278T patent/ES2058083T3/es not_active Expired - Lifetime
- 1987-09-11 JP JP62226755A patent/JP2837160B2/ja not_active Expired - Fee Related
- 1987-09-11 ZA ZA876807A patent/ZA876807B/xx unknown
- 1987-09-11 CA CA000546724A patent/CA1337717C/en not_active Expired - Fee Related
-
1994
- 1994-02-28 BG BG098602A patent/BG62229B2/bg unknown
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1996
- 1996-12-27 JP JP8349507A patent/JP2758394B2/ja not_active Expired - Fee Related
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1997
- 1997-05-12 BR BR1100843-1A patent/BR1100843A/pt active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| FI873948A (fi) | 1988-03-14 |
| FI873948A0 (fi) | 1987-09-11 |
| JP2837160B2 (ja) | 1998-12-14 |
| EP0260610A2 (de) | 1988-03-23 |
| BR1100843A (pt) | 2000-04-18 |
| JPH09294584A (ja) | 1997-11-18 |
| FI91421C (fi) | 1994-06-27 |
| DK473887D0 (da) | 1987-09-11 |
| FI91421B (fi) | 1994-03-15 |
| US5231024A (en) | 1993-07-27 |
| JP2758394B2 (ja) | 1998-05-28 |
| CA1337717C (en) | 1995-12-12 |
| JPS63157977A (ja) | 1988-06-30 |
| DE3787241D1 (de) | 1993-10-07 |
| EP0260610A3 (en) | 1989-01-11 |
| EP0260610B1 (de) | 1993-09-01 |
| ES2058083T3 (es) | 1994-11-01 |
| DK473887A (da) | 1988-03-11 |
| ZA876807B (en) | 1989-05-30 |
| DE3631229A1 (de) | 1988-03-24 |
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