BG61812B1 - Комплекси на 3-морфолино-сиднонимин с включения - Google Patents
Комплекси на 3-морфолино-сиднонимин с включения Download PDFInfo
- Publication number
- BG61812B1 BG61812B1 BG95530A BG9553091A BG61812B1 BG 61812 B1 BG61812 B1 BG 61812B1 BG 95530 A BG95530 A BG 95530A BG 9553091 A BG9553091 A BG 9553091A BG 61812 B1 BG61812 B1 BG 61812B1
- Authority
- BG
- Bulgaria
- Prior art keywords
- cyclodextrin
- sin
- morpholino
- complex
- salt
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
- C08B37/0015—Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/04—1,2,3-Oxadiazoles; Hydrogenated 1,2,3-oxadiazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Cardiology (AREA)
- Animal Behavior & Ethology (AREA)
- Polymers & Plastics (AREA)
- Materials Engineering (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU901869A HU212730B (en) | 1990-03-28 | 1990-03-28 | Process for producing inclusion complexes of cyclodextrine or its derivative and 3-morpholino-sydnonimine or its salt or its tautomer and pharmaceutical compositions containing them |
| PCT/HU1991/000013 WO1991014681A1 (en) | 1990-03-28 | 1991-03-28 | Inclusion complexes of 3-morpholino-sydnonimine or its salts or its tautomer isomer, process for the preparation thereof, and pharmaceutical compositions containing the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BG95530A BG95530A (bg) | 1993-12-24 |
| BG61812B1 true BG61812B1 (bg) | 1998-06-30 |
Family
ID=10956597
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG95530A BG61812B1 (bg) | 1990-03-28 | 1991-11-27 | Комплекси на 3-морфолино-сиднонимин с включения |
Country Status (33)
| Country | Link |
|---|---|
| US (1) | US5298496A (hu) |
| EP (1) | EP0478732B1 (hu) |
| JP (1) | JP2549961B2 (hu) |
| KR (1) | KR950004706B1 (hu) |
| CN (1) | CN1051081C (hu) |
| AT (1) | ATE170849T1 (hu) |
| AU (1) | AU635835B2 (hu) |
| BG (1) | BG61812B1 (hu) |
| BR (1) | BR9105137A (hu) |
| CA (1) | CA2054213C (hu) |
| CZ (1) | CZ285695B6 (hu) |
| DE (1) | DE69130146T2 (hu) |
| DK (1) | DK0478732T3 (hu) |
| ES (1) | ES2121780T3 (hu) |
| FI (1) | FI104882B (hu) |
| GE (1) | GEP19991743B (hu) |
| HK (1) | HK1011688A1 (hu) |
| HR (1) | HRP920560B1 (hu) |
| HU (2) | HU211648A9 (hu) |
| LT (1) | LT3257B (hu) |
| LV (1) | LV10087B (hu) |
| MC (1) | MC2186A1 (hu) |
| MD (1) | MD776C2 (hu) |
| MW (1) | MW6891A1 (hu) |
| NO (1) | NO303634B1 (hu) |
| OA (1) | OA09522A (hu) |
| PL (1) | PL165866B1 (hu) |
| RO (1) | RO109336B1 (hu) |
| RU (1) | RU2107695C1 (hu) |
| SI (1) | SI9110909B (hu) |
| TJ (1) | TJ189R3 (hu) |
| UA (1) | UA27242C2 (hu) |
| WO (1) | WO1991014681A1 (hu) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU210921B (en) * | 1990-03-28 | 1995-09-28 | Chinoin Gyogyszer Es Vegyeszet | Process for preparing inclusion complexes of n-ethoxycarbonyl-3-morpholino-sydnonimine formed with cyclodextrines and pharmaceutical compositions containing them |
| DE4117249C2 (de) * | 1991-05-27 | 1998-05-14 | Christian Dr Stief | Linsidomin zur Behandlung erektiler Dysfunktionen |
| HU213200B (en) | 1993-05-12 | 1997-03-28 | Chinoin Gyogyszer Es Vegyeszet | The cyclodextrin or cyclodextrin derivative cluster complexes of taxol, taxotere, or taxus, pharmaceutical preparations containing them and process for their production |
| HU218280B (en) * | 1994-04-26 | 2000-07-28 | Cyclodextrin inclusion complexes containing sin-1a which are stable intheir solid state, process for their preparation and pharmaceutical compositions containing the comlexes | |
| GB9915231D0 (en) | 1999-06-29 | 1999-09-01 | Pfizer Ltd | Pharmaceutical complex |
| FR2805462B1 (fr) * | 2000-02-24 | 2003-08-15 | Therabel Res | Nouvelle forme galenique orale a liberation prolongee de la molsidomine |
| WO2001085218A2 (en) * | 2000-05-11 | 2001-11-15 | Eastman Chemical Company | Acylated cyclodextrin guest inclusion complexes |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1496056A (fr) * | 1964-06-08 | 1967-09-29 | Takeda Chemical Industries Ltd | Nouveaux composés chimiques du type sydnonimine |
| DE3221425A1 (de) * | 1982-06-07 | 1983-12-08 | Boehringer Ingelheim KG, 6507 Ingelheim | Hydrolyseempfindlichen wirkstoff enthaltende, lagerstabile tablette |
| DE3346638A1 (de) * | 1983-12-23 | 1985-07-04 | Cassella Ag, 6000 Frankfurt | Photostabilisierung von molsidomin |
| GB8506792D0 (en) * | 1985-03-15 | 1985-04-17 | Janssen Pharmaceutica Nv | Derivatives of y-cyclodextrin |
| DE3522191A1 (de) * | 1985-06-21 | 1987-01-15 | Cassella Ag | Photostabilisierung von sydnoniminen |
| GB8613688D0 (en) * | 1986-06-05 | 1986-07-09 | Euro Celtique Sa | Pharmaceutical composition |
| JPH0819004B2 (ja) * | 1986-12-26 | 1996-02-28 | 日清製粉株式会社 | 徐放性医薬製剤 |
| IT1204725B (it) * | 1987-06-17 | 1989-03-10 | Edmond Pharma Srl | Complessi di inclusione del dipiridamolo con ciclodestrine |
| SE8904296D0 (sv) * | 1989-12-21 | 1989-12-21 | Pharmacia Ab | Transdermal system |
| WO1991015346A1 (de) * | 1990-04-06 | 1991-10-17 | Gerhard Blatt | Anlage zur behandlung von betonsteinen |
-
1990
- 1990-03-28 HU HU90P/P00224P patent/HU211648A9/hu unknown
- 1990-03-28 HU HU901869A patent/HU212730B/hu unknown
-
1991
- 1991-03-28 DK DK91907217T patent/DK0478732T3/da active
- 1991-03-28 RU SU5010582A patent/RU2107695C1/ru active
- 1991-03-28 JP JP3506356A patent/JP2549961B2/ja not_active Expired - Lifetime
- 1991-03-28 CZ CS91852A patent/CZ285695B6/cs not_active IP Right Cessation
- 1991-03-28 MD MD94-0334A patent/MD776C2/ro active IP Right Grant
- 1991-03-28 UA UA93060611A patent/UA27242C2/uk unknown
- 1991-03-28 MC MC@@@@D patent/MC2186A1/xx unknown
- 1991-03-28 CA CA002054213A patent/CA2054213C/en not_active Expired - Lifetime
- 1991-03-28 BR BR919105137A patent/BR9105137A/pt not_active Application Discontinuation
- 1991-03-28 SI SI9110909A patent/SI9110909B/sl unknown
- 1991-03-28 PL PL91293020A patent/PL165866B1/pl unknown
- 1991-03-28 RO RO148828A patent/RO109336B1/ro unknown
- 1991-03-28 CN CN91102699A patent/CN1051081C/zh not_active Expired - Fee Related
- 1991-03-28 DE DE69130146T patent/DE69130146T2/de not_active Expired - Lifetime
- 1991-03-28 WO PCT/HU1991/000013 patent/WO1991014681A1/en active IP Right Grant
- 1991-03-28 US US07/793,389 patent/US5298496A/en not_active Expired - Lifetime
- 1991-03-28 EP EP91907217A patent/EP0478732B1/en not_active Expired - Lifetime
- 1991-03-28 AU AU75493/91A patent/AU635835B2/en not_active Expired
- 1991-03-28 AT AT91907217T patent/ATE170849T1/de not_active IP Right Cessation
- 1991-03-28 KR KR1019910701671A patent/KR950004706B1/ko not_active IP Right Cessation
- 1991-03-28 ES ES91907217T patent/ES2121780T3/es not_active Expired - Lifetime
- 1991-11-08 OA OA60095A patent/OA09522A/en unknown
- 1991-11-13 MW MW6891A patent/MW6891A1/xx unknown
- 1991-11-26 FI FI915570A patent/FI104882B/fi active
- 1991-11-27 NO NO914650A patent/NO303634B1/no not_active IP Right Cessation
- 1991-11-27 BG BG95530A patent/BG61812B1/bg unknown
-
1992
- 1992-09-28 HR HRP-909/91A patent/HRP920560B1/xx not_active IP Right Cessation
- 1992-12-30 LV LVP-92-588A patent/LV10087B/lv unknown
-
1993
- 1993-03-05 LT LTIP387A patent/LT3257B/lt not_active IP Right Cessation
- 1993-06-16 GE GEAP1993880A patent/GEP19991743B/en unknown
-
1994
- 1994-11-28 TJ TJ94000008A patent/TJ189R3/xx unknown
-
1998
- 1998-12-07 HK HK98112917A patent/HK1011688A1/xx not_active IP Right Cessation
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