NO914650L - Inklusjonskomplekser av 3-morfolino-sydnonimin eller detstautomer-isomer, fremgangsmaate for fremstilling av disse og farmasoeytiske preparater inneholdende disse - Google Patents

Inklusjonskomplekser av 3-morfolino-sydnonimin eller detstautomer-isomer, fremgangsmaate for fremstilling av disse og farmasoeytiske preparater inneholdende disse

Info

Publication number
NO914650L
NO914650L NO91914650A NO914650A NO914650L NO 914650 L NO914650 L NO 914650L NO 91914650 A NO91914650 A NO 91914650A NO 914650 A NO914650 A NO 914650A NO 914650 L NO914650 L NO 914650L
Authority
NO
Norway
Prior art keywords
sydnonimine
morpholino
preparation
isoms
detstautomer
Prior art date
Application number
NO91914650A
Other languages
English (en)
Other versions
NO914650D0 (no
NO303634B1 (no
Inventor
Maria Vikmon
Jozsef Szejtli
Lajos Szente
Jozsef Gaal
Istvan Hermecz
Agnes Horvath
Katalin Marmarosi
Gabor Horvath
Iren Munkacsi
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of NO914650D0 publication Critical patent/NO914650D0/no
Publication of NO914650L publication Critical patent/NO914650L/no
Publication of NO303634B1 publication Critical patent/NO303634B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
    • C08B37/0015—Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/04—1,2,3-Oxadiazoles; Hydrogenated 1,2,3-oxadiazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
NO914650A 1990-03-28 1991-11-27 AnalogifremgangsmÕte for fremstilling av et farmas°ytisk aktivt inklusjonskompleks av 3-morfolino-sydnonimin og dets tautomerisomere former, spesielt SIN-1A, eller deres salter, dannet med et syklodekstrinderivat NO303634B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU901869A HU212730B (en) 1990-03-28 1990-03-28 Process for producing inclusion complexes of cyclodextrine or its derivative and 3-morpholino-sydnonimine or its salt or its tautomer and pharmaceutical compositions containing them
PCT/HU1991/000013 WO1991014681A1 (en) 1990-03-28 1991-03-28 Inclusion complexes of 3-morpholino-sydnonimine or its salts or its tautomer isomer, process for the preparation thereof, and pharmaceutical compositions containing the same

Publications (3)

Publication Number Publication Date
NO914650D0 NO914650D0 (no) 1991-11-27
NO914650L true NO914650L (no) 1991-11-27
NO303634B1 NO303634B1 (no) 1998-08-10

Family

ID=10956597

Family Applications (1)

Application Number Title Priority Date Filing Date
NO914650A NO303634B1 (no) 1990-03-28 1991-11-27 AnalogifremgangsmÕte for fremstilling av et farmas°ytisk aktivt inklusjonskompleks av 3-morfolino-sydnonimin og dets tautomerisomere former, spesielt SIN-1A, eller deres salter, dannet med et syklodekstrinderivat

Country Status (33)

Country Link
US (1) US5298496A (no)
EP (1) EP0478732B1 (no)
JP (1) JP2549961B2 (no)
KR (1) KR950004706B1 (no)
CN (1) CN1051081C (no)
AT (1) ATE170849T1 (no)
AU (1) AU635835B2 (no)
BG (1) BG61812B1 (no)
BR (1) BR9105137A (no)
CA (1) CA2054213C (no)
CZ (1) CZ285695B6 (no)
DE (1) DE69130146T2 (no)
DK (1) DK0478732T3 (no)
ES (1) ES2121780T3 (no)
FI (1) FI104882B (no)
GE (1) GEP19991743B (no)
HK (1) HK1011688A1 (no)
HR (1) HRP920560B1 (no)
HU (2) HU212730B (no)
LT (1) LT3257B (no)
LV (1) LV10087B (no)
MC (1) MC2186A1 (no)
MD (1) MD776C2 (no)
MW (1) MW6891A1 (no)
NO (1) NO303634B1 (no)
OA (1) OA09522A (no)
PL (1) PL165866B1 (no)
RO (1) RO109336B1 (no)
RU (1) RU2107695C1 (no)
SI (1) SI9110909B (no)
TJ (1) TJ189R3 (no)
UA (1) UA27242C2 (no)
WO (1) WO1991014681A1 (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU210921B (en) * 1990-03-28 1995-09-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing inclusion complexes of n-ethoxycarbonyl-3-morpholino-sydnonimine formed with cyclodextrines and pharmaceutical compositions containing them
DE4117249C2 (de) * 1991-05-27 1998-05-14 Christian Dr Stief Linsidomin zur Behandlung erektiler Dysfunktionen
HU213200B (en) 1993-05-12 1997-03-28 Chinoin Gyogyszer Es Vegyeszet The cyclodextrin or cyclodextrin derivative cluster complexes of taxol, taxotere, or taxus, pharmaceutical preparations containing them and process for their production
HU218280B (en) * 1994-04-26 2000-07-28 Cyclodextrin inclusion complexes containing sin-1a which are stable intheir solid state, process for their preparation and pharmaceutical compositions containing the comlexes
GB9915231D0 (en) 1999-06-29 1999-09-01 Pfizer Ltd Pharmaceutical complex
FR2805462B1 (fr) * 2000-02-24 2003-08-15 Therabel Res Nouvelle forme galenique orale a liberation prolongee de la molsidomine
DE60117777T2 (de) * 2000-05-11 2006-08-17 Eastman Chemical Co., Kingsport Acylierte zyclodextrin guest-inklusion komplexe

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1496056A (fr) * 1964-06-08 1967-09-29 Takeda Chemical Industries Ltd Nouveaux composés chimiques du type sydnonimine
DE3221425A1 (de) * 1982-06-07 1983-12-08 Boehringer Ingelheim KG, 6507 Ingelheim Hydrolyseempfindlichen wirkstoff enthaltende, lagerstabile tablette
DE3346638A1 (de) * 1983-12-23 1985-07-04 Cassella Ag, 6000 Frankfurt Photostabilisierung von molsidomin
GB8506792D0 (en) * 1985-03-15 1985-04-17 Janssen Pharmaceutica Nv Derivatives of y-cyclodextrin
DE3522191A1 (de) * 1985-06-21 1987-01-15 Cassella Ag Photostabilisierung von sydnoniminen
GB8613688D0 (en) * 1986-06-05 1986-07-09 Euro Celtique Sa Pharmaceutical composition
JPH0819004B2 (ja) * 1986-12-26 1996-02-28 日清製粉株式会社 徐放性医薬製剤
IT1204725B (it) * 1987-06-17 1989-03-10 Edmond Pharma Srl Complessi di inclusione del dipiridamolo con ciclodestrine
SE8904296D0 (sv) * 1989-12-21 1989-12-21 Pharmacia Ab Transdermal system
WO1991015346A1 (de) * 1990-04-06 1991-10-17 Gerhard Blatt Anlage zur behandlung von betonsteinen

Also Published As

Publication number Publication date
AU635835B2 (en) 1993-04-01
OA09522A (en) 1992-11-15
FI915570A0 (fi) 1991-11-26
DE69130146T2 (de) 1999-04-01
NO914650D0 (no) 1991-11-27
US5298496A (en) 1994-03-29
EP0478732B1 (en) 1998-09-09
KR950004706B1 (ko) 1995-05-04
MD940334A (en) 1996-10-31
CA2054213A1 (en) 1991-09-29
PL165866B1 (pl) 1995-02-28
GEP19991743B (en) 1999-09-10
EP0478732A1 (en) 1992-04-08
SI9110909B (sl) 1999-02-28
AU7549391A (en) 1991-10-21
LTIP387A (en) 1994-09-25
LV10087B (en) 1995-02-20
BG61812B1 (bg) 1998-06-30
RU2107695C1 (ru) 1998-03-27
BR9105137A (pt) 1992-08-04
CZ285695B6 (cs) 1999-10-13
HK1011688A1 (en) 1999-07-16
MD776C2 (ro) 1998-05-31
LT3257B (en) 1995-05-25
TJ189R3 (en) 1998-10-28
JP2549961B2 (ja) 1996-10-30
KR920701183A (ko) 1992-08-11
DE69130146D1 (de) 1998-10-15
HU212730B (en) 1996-10-28
WO1991014681A1 (en) 1991-10-03
CN1055928A (zh) 1991-11-06
CN1051081C (zh) 2000-04-05
DK0478732T3 (da) 1999-06-07
ATE170849T1 (de) 1998-09-15
ES2121780T3 (es) 1998-12-16
SI9110909A (sl) 1998-06-30
MW6891A1 (en) 1993-07-14
MD776B2 (en) 1997-07-31
HRP920560B1 (en) 1999-12-31
CZ85291A3 (en) 1993-11-17
HU901869D0 (en) 1990-07-28
HUT58110A (en) 1992-01-28
LV10087A (lv) 1994-05-10
PL293020A1 (en) 1992-12-28
NO303634B1 (no) 1998-08-10
MC2186A1 (fr) 1992-09-16
UA27242C2 (uk) 2000-08-15
HU211648A9 (en) 1995-12-28
HRP920560A2 (hr) 1994-04-30
FI104882B (fi) 2000-04-28
JPH04506221A (ja) 1992-10-29
RO109336B1 (ro) 1995-01-30
CA2054213C (en) 1998-12-01

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