ES8304937A1 - Procedimiento para la obtencion de derivados de 2-amino-piridina sustituidos. - Google Patents

Procedimiento para la obtencion de derivados de 2-amino-piridina sustituidos.

Info

Publication number
ES8304937A1
ES8304937A1 ES513392A ES513392A ES8304937A1 ES 8304937 A1 ES8304937 A1 ES 8304937A1 ES 513392 A ES513392 A ES 513392A ES 513392 A ES513392 A ES 513392A ES 8304937 A1 ES8304937 A1 ES 8304937A1
Authority
ES
Spain
Prior art keywords
preparation
substituted
amino
medicaments
pyridine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES513392A
Other languages
English (en)
Other versions
ES513392A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES513392A0 publication Critical patent/ES513392A0/es
Publication of ES8304937A1 publication Critical patent/ES8304937A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE 2-AMINOPIRIDINA SUSTITUIDOS Y DE SUS SALES FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE M Y N VALEN 0 O 1, Y R, R , R , R , R , R E Y PUEDEN SER VARIOS TIPOS DE RADICALES. CONSISTE EN LA REACCION DE OXIDACION DE DERIVADOS DE 2-AMINO-3,4-DIHIDROPIRIDINA DE FORMULA (II), EN LA QUE TODOS LOS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA OXIDACION SE LLEVA A CABO CON OXIGENO EN UN DISOLVENTE ORGANICO INERTE, EN PRESENCIA DE UN CATALIZADOR BASICO, TAL COMO BASES ALCALINAS O ALCALINOTERREAS, A TEMPERATURAS ENTRE -80 C Y 100 C. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO INHIBIDORES DE LA ABSORCION DE LIPIDOS.
ES513392A 1981-06-24 1982-06-23 Procedimiento para la obtencion de derivados de 2-amino-piridina sustituidos. Expired ES8304937A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813124673 DE3124673A1 (de) 1981-06-24 1981-06-24 Subsituierte 2-amino-pyridinderivate, verfahren zu ihrer herstellung, ihre verwendung in arzneimitteln, sowie deren herstellung

Publications (2)

Publication Number Publication Date
ES513392A0 ES513392A0 (es) 1983-03-16
ES8304937A1 true ES8304937A1 (es) 1983-03-16

Family

ID=6135207

Family Applications (1)

Application Number Title Priority Date Filing Date
ES513392A Expired ES8304937A1 (es) 1981-06-24 1982-06-23 Procedimiento para la obtencion de derivados de 2-amino-piridina sustituidos.

Country Status (6)

Country Link
US (1) US4469696A (es)
EP (1) EP0068259A1 (es)
JP (1) JPS58963A (es)
DE (1) DE3124673A1 (es)
DK (1) DK282682A (es)
ES (1) ES8304937A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4439437A (en) * 1981-04-28 1984-03-27 Smith Kline & French Laboratories Limited 2-[2-Thiazolyl or 2-guanidino-4-thiazolyl methylthioethyl(or butyl)amino]-3-(hydroxy or carboxy)pyridines, compositions containing same and method of use
JPH0688973B2 (ja) * 1987-03-12 1994-11-09 京都薬品工業株式会社 １，４−ジヒドロピリジン誘導体
US5021421A (en) * 1989-03-03 1991-06-04 Dainippon Pharmaceutical Co., Ltd. 2-(1-Piperazinyl)-4-phenylcycloalkanopyridine derivatives, processes for the production thereof, and pharmaceutical composition containing the same
WO1993022086A1 (en) * 1992-04-28 1993-11-11 Alcan International Limited Method for preventing sticking on a twin roll caster
EP1761516B1 (de) * 2004-06-25 2007-11-28 Basf Aktiengesellschaft 2, 4, 5, 6-substituierte pyridine, verfahren zu ihrer herstellung und ihre verwendung zur bekämpfung von schadpilzen
WO2006113704A2 (en) * 2005-04-18 2006-10-26 Neurogen Corporation Subtituted heteroaryl cb1 antagonists
US11534795B2 (en) * 2018-10-23 2022-12-27 Research & Business Foundation Sungkyunkwan University Preparing method of monomolecular nano-thin film

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2230392A1 (de) * 1972-06-22 1974-01-31 Cassella Farbwerke Mainkur Ag Substituierte pyridinverbindungen und verfahren zu ihrer herstellung
EP0000816A1 (en) * 1977-08-06 1979-02-21 Beecham Group Plc Substituted amino-pyridine derivatives, processes for their preparation and pharmaceutical compositions containing them
EP0013153B1 (en) * 1978-12-27 1982-12-22 Beecham Group Plc 6-amino pyridine carboxylic acid derivatives, a process for their preparation and pharmaceutical compositions containing them
DE2949701A1 (de) * 1979-12-11 1981-06-19 Bayer Ag, 5090 Leverkusen Substituierte 2-amino-3,4-dihydropyridinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
DE3124673A1 (de) 1983-01-13
ES513392A0 (es) 1983-03-16
US4469696A (en) 1984-09-04
JPS58963A (ja) 1983-01-06
DK282682A (da) 1982-12-25
EP0068259A1 (de) 1983-01-05

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19991007