BG60679B1 - Аналози на 1,3-оксатиоланнуклеозида - Google Patents

Аналози на 1,3-оксатиоланнуклеозида Download PDF

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Publication number
BG60679B1
BG60679B1 BG95705A BG9570591A BG60679B1 BG 60679 B1 BG60679 B1 BG 60679B1 BG 95705 A BG95705 A BG 95705A BG 9570591 A BG9570591 A BG 9570591A BG 60679 B1 BG60679 B1 BG 60679B1
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BG
Bulgaria
Prior art keywords
compound according
compound
enantiomer
weight
acid
Prior art date
Application number
BG95705A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG95705A (bg
Inventor
Jonathan A Coates
Ian M Mutton
Charles R Penn
Richard Storer
Christopher Williamson
Original Assignee
Iaf Biochem Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10675345&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BG60679(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Iaf Biochem Int filed Critical Iaf Biochem Int
Publication of BG95705A publication Critical patent/BG95705A/bg
Publication of BG60679B1 publication Critical patent/BG60679B1/bg

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D411/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D411/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D411/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
BG95705A 1990-05-02 1991-12-28 Аналози на 1,3-оксатиоланнуклеозида BG60679B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909009861A GB9009861D0 (en) 1990-05-02 1990-05-02 Chemical compounds
PCT/GB1991/000706 WO1991017159A1 (en) 1990-05-02 1991-05-02 1,3-oxathiolane nucleoside analogues

Publications (2)

Publication Number Publication Date
BG95705A BG95705A (bg) 1993-12-24
BG60679B1 true BG60679B1 (bg) 1995-12-29

Family

ID=10675345

Family Applications (1)

Application Number Title Priority Date Filing Date
BG95705A BG60679B1 (bg) 1990-05-02 1991-12-28 Аналози на 1,3-оксатиоланнуклеозида

Country Status (35)

Country Link
US (3) US6180639B1 (ja)
EP (2) EP0625150A1 (ja)
JP (3) JP2927546B2 (ja)
KR (1) KR960007532B1 (ja)
CN (3) CN1036196C (ja)
AP (1) AP182A (ja)
BG (1) BG60679B1 (ja)
CA (2) CA2059263C (ja)
CZ (1) CZ288499B6 (ja)
EG (1) EG19958A (ja)
FI (1) FI111722B (ja)
GB (1) GB9009861D0 (ja)
GE (1) GEP19991705B (ja)
HK (1) HK1043940B (ja)
HU (2) HUT64335A (ja)
IE (1) IE911482A1 (ja)
IL (1) IL98025A (ja)
MA (1) MA22144A1 (ja)
MD (1) MD809C2 (ja)
MY (1) MY109796A (ja)
NO (1) NO180377B (ja)
NZ (1) NZ238017A (ja)
OA (1) OA09559A (ja)
PL (1) PL167682B1 (ja)
PT (1) PT97520B (ja)
RO (1) RO112616B1 (ja)
RU (1) RU2099338C1 (ja)
SG (1) SG46383A1 (ja)
SK (1) SK283430B6 (ja)
TN (1) TNSN91029A1 (ja)
TW (2) TWI222448B (ja)
UA (1) UA40589C2 (ja)
WO (1) WO1991017159A1 (ja)
YU (1) YU78291A (ja)
ZA (1) ZA913293B (ja)

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Also Published As

Publication number Publication date
CN1036196C (zh) 1997-10-22
AP9100255A0 (en) 1991-07-31
JPH05501117A (ja) 1993-03-04
CA2059263A1 (en) 1991-11-03
SK283430B6 (sk) 2003-07-01
EP1062950A3 (en) 2003-05-02
TWI222448B (en) 2004-10-21
NO920018D0 (no) 1992-01-02
CN1326743A (zh) 2001-12-19
RU2099338C1 (ru) 1997-12-20
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WO1991017159A1 (en) 1991-11-14
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FI916165A0 (fi) 1991-12-30
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AU651345B2 (en) 1994-07-21
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US20030004175A1 (en) 2003-01-02
KR920702682A (ko) 1992-10-06
CZ288499B6 (en) 2001-06-13
FI111722B (fi) 2003-09-15
UA40589C2 (uk) 2001-08-15
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TW366346B (en) 1999-08-11
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IL98025A (en) 1996-10-16
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HK1043940B (zh) 2005-03-24
IL98025A0 (en) 1992-06-21
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AP182A (en) 1992-06-30
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AU7771991A (en) 1991-11-27
MD809B2 (en) 1997-08-31
SG46383A1 (en) 1998-02-20
OA09559A (fr) 1993-01-31
JP2927546B2 (ja) 1999-07-28
GB9009861D0 (en) 1990-06-27
MA22144A1 (fr) 1991-12-31
MY109796A (en) 1997-07-30
PL167682B1 (pl) 1995-10-31
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