IT1290447B1 - Derivati 1,3-ossatiolanici ad attivita' antivirale - Google Patents

Derivati 1,3-ossatiolanici ad attivita' antivirale

Info

Publication number
IT1290447B1
IT1290447B1 IT97MI000737A ITMI970737A IT1290447B1 IT 1290447 B1 IT1290447 B1 IT 1290447B1 IT 97MI000737 A IT97MI000737 A IT 97MI000737A IT MI970737 A ITMI970737 A IT MI970737A IT 1290447 B1 IT1290447 B1 IT 1290447B1
Authority
IT
Italy
Prior art keywords
ossatiolanic
derivatives
viral activity
viral
activity
Prior art date
Application number
IT97MI000737A
Other languages
English (en)
Inventor
Franco Pellacini
Domenico Ungheri
Giovanna Schioppacassi
Jean-Louis Kraus
Michel Camplo
Nicolas Mourier
Jean-Claude Chermann
Original Assignee
Zambon Spa
I N S E R M Inst Nationale De
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa, I N S E R M Inst Nationale De filed Critical Zambon Spa
Priority to IT97MI000737A priority Critical patent/IT1290447B1/it
Priority to US09/381,635 priority patent/US6214833B1/en
Priority to CA002285320A priority patent/CA2285320A1/en
Priority to AU70407/98A priority patent/AU7040798A/en
Priority to EP98917071A priority patent/EP0970075A1/en
Priority to PCT/EP1998/001734 priority patent/WO1998043972A1/en
Publication of ITMI970737A1 publication Critical patent/ITMI970737A1/it
Application granted granted Critical
Publication of IT1290447B1 publication Critical patent/IT1290447B1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D411/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D411/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D411/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT97MI000737A 1997-03-28 1997-03-28 Derivati 1,3-ossatiolanici ad attivita' antivirale IT1290447B1 (it)

Priority Applications (6)

Application Number Priority Date Filing Date Title
IT97MI000737A IT1290447B1 (it) 1997-03-28 1997-03-28 Derivati 1,3-ossatiolanici ad attivita' antivirale
US09/381,635 US6214833B1 (en) 1997-03-28 1998-03-24 Pyrimidinone-1,3-oxathiolane derivatives with antiviral activity
CA002285320A CA2285320A1 (en) 1997-03-28 1998-03-24 Pyrimidinone-1,3-oxathiolane derivatives with antiviral activity
AU70407/98A AU7040798A (en) 1997-03-28 1998-03-24 Pyrimidinone-1,3-oxathiolane derivatives with antiviral activity
EP98917071A EP0970075A1 (en) 1997-03-28 1998-03-24 Pyrimidinone-1,3-oxathiolane derivatives with antiviral activity
PCT/EP1998/001734 WO1998043972A1 (en) 1997-03-28 1998-03-24 PYRIMIDINONE-1,3-OXATHIOLANE DERIVATIVES HAVING ANTIVIRAL ACTIVITY

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT97MI000737A IT1290447B1 (it) 1997-03-28 1997-03-28 Derivati 1,3-ossatiolanici ad attivita' antivirale

Publications (2)

Publication Number Publication Date
ITMI970737A1 ITMI970737A1 (it) 1998-09-28
IT1290447B1 true IT1290447B1 (it) 1998-12-03

Family

ID=11376687

Family Applications (1)

Application Number Title Priority Date Filing Date
IT97MI000737A IT1290447B1 (it) 1997-03-28 1997-03-28 Derivati 1,3-ossatiolanici ad attivita' antivirale

Country Status (6)

Country Link
US (1) US6214833B1 (it)
EP (1) EP0970075A1 (it)
AU (1) AU7040798A (it)
CA (1) CA2285320A1 (it)
IT (1) IT1290447B1 (it)
WO (1) WO1998043972A1 (it)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ20013678A3 (cs) 1999-04-13 2002-07-17 Basf Aktiengesellschaft Ligandy integrinového receptoru
BRPI0813709A2 (pt) 2007-07-09 2015-01-06 Eastern Virginia Med School Derivados de nucleosídeo substituído com propriedades antiviral e antimicrobiana
SG11201608538UA (en) * 2014-04-29 2016-11-29 Biosearch Technologies Inc Compounds compositions and methods including thermally labile moieties
US9708350B2 (en) 2014-12-04 2017-07-18 Shin-Etsu Chemical Co., Ltd. Method for producing polyalkylene glycol derivative having amino group at end, polymerization initiator for use in the same, and alcohol compound as raw material for the polymerization initiator
JP6460937B2 (ja) * 2014-12-04 2019-01-30 信越化学工業株式会社 末端にアミノ基を有するポリアルキレングリコール誘導体の製造方法
US10377775B2 (en) 2014-12-04 2019-08-13 Shin-Etsu Chemical Co., Ltd. Method for producing polyalkylene glycol derivative having amino group at end

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0429436A3 (en) * 1985-12-06 1991-12-27 The University Of Kansas Prodrugs of rapamycin
DK406686D0 (da) * 1986-08-26 1986-08-26 Hans Bundgaard Carboxylsyrederivater
US5047407A (en) 1989-02-08 1991-09-10 Iaf Biochem International, Inc. 2-substituted-5-substituted-1,3-oxathiolanes with antiviral properties
HU226137B1 (en) 1989-02-08 2008-05-28 Shire Canada Inc Process for preparing substituted 1,3-oxathiolanes with antiviral properties
GB9009861D0 (en) * 1990-05-02 1990-06-27 Glaxo Group Ltd Chemical compounds
JP2960164B2 (ja) 1990-11-13 1999-10-06 バイオケム ファーマ インコーポレイテッド 抗ウイルス特性を有する置換１，３−オキサチオラン類および置換１，３−ジチオラン類
NZ250842A (en) 1991-02-22 1996-03-26 Univ Emory Resolution of a racemic mixture of nucleoside enantiomers such as 2-hydroxymethyl-5-(5-fluorocytosin-1-yl)-1,3-oxathiolane (ftc)
FR2720397B1 (fr) * 1994-05-24 1996-08-23 Laphal Laboratoires Sa Nouveaux oxathiolanes, leur procédé de préparation et les compositions pharmaceutiques qui en renferment.
IT1276901B1 (it) * 1994-12-13 1997-11-03 Zambon Spa Derivati dell'eritromicina a 9-0-ossina dotati di attivita' antibiotica

Also Published As

Publication number Publication date
ITMI970737A1 (it) 1998-09-28
EP0970075A1 (en) 2000-01-12
US6214833B1 (en) 2001-04-10
AU7040798A (en) 1998-10-22
CA2285320A1 (en) 1998-10-08
WO1998043972A1 (en) 1998-10-08

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Legal Events

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0001 Granted