DK0966477T3 - 3'-N-oxid, 3'-N-dimethylamin, 9-oxim-erythromycin A-derivater - Google Patents

3'-N-oxid, 3'-N-dimethylamin, 9-oxim-erythromycin A-derivater

Info

Publication number
DK0966477T3
DK0966477T3 DK98904822T DK98904822T DK0966477T3 DK 0966477 T3 DK0966477 T3 DK 0966477T3 DK 98904822 T DK98904822 T DK 98904822T DK 98904822 T DK98904822 T DK 98904822T DK 0966477 T3 DK0966477 T3 DK 0966477T3
Authority
DK
Denmark
Prior art keywords
erythromycin
dimethylamine
oxime
derivatives
oxide
Prior art date
Application number
DK98904822T
Other languages
English (en)
Inventor
Yi-Yin Ku
David A Riley
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of DK0966477T3 publication Critical patent/DK0966477T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK98904822T 1997-02-13 1998-02-03 3'-N-oxid, 3'-N-dimethylamin, 9-oxim-erythromycin A-derivater DK0966477T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/800,009 US5864023A (en) 1997-02-13 1997-02-13 3'-N'oxide, 3'-n-dimethylamine, 9-oxime erythromycin a derivatives
PCT/US1998/001929 WO1998035976A1 (en) 1997-02-13 1998-02-03 3'-n-oxide, 3'-n-dimethylamine, 9-oxime erythromycin a derivatives

Publications (1)

Publication Number Publication Date
DK0966477T3 true DK0966477T3 (da) 2004-02-23

Family

ID=25177295

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98904822T DK0966477T3 (da) 1997-02-13 1998-02-03 3'-N-oxid, 3'-N-dimethylamin, 9-oxim-erythromycin A-derivater

Country Status (25)

Country Link
US (1) US5864023A (da)
EP (1) EP0966477B1 (da)
JP (1) JP2001512456A (da)
KR (1) KR100561326B1 (da)
CN (1) CN1326865C (da)
AR (1) AR012032A1 (da)
AT (1) ATE252108T1 (da)
AU (1) AU725274B2 (da)
BG (1) BG64099B1 (da)
BR (1) BR9807349A (da)
CA (1) CA2279932C (da)
CZ (1) CZ294481B6 (da)
DE (1) DE69818977T2 (da)
DK (1) DK0966477T3 (da)
ES (1) ES2212266T3 (da)
HU (1) HUP0001330A3 (da)
IL (1) IL130697A0 (da)
NO (1) NO993876D0 (da)
NZ (1) NZ336482A (da)
PL (1) PL187357B1 (da)
PT (1) PT966477E (da)
SK (1) SK284157B6 (da)
TR (1) TR199901874T2 (da)
WO (1) WO1998035976A1 (da)
ZA (1) ZA98986B (da)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100317907B1 (ko) * 1998-11-24 2001-12-24 김 완 주 신규한 중간체, 이를 이용한 마크로라이드계 항생제의제조방법
US6437106B1 (en) 1999-06-24 2002-08-20 Abbott Laboratories Process for preparing 6-o-substituted erythromycin derivatives
KR20010008496A (ko) * 1999-07-01 2001-02-05 유충식 6-오-메틸 에리트로마이신의 제조방법
KR100336447B1 (ko) * 1999-11-24 2002-05-15 민경윤 클라리스로마이신의 개선된 제조방법
KR20020070991A (ko) 1999-12-16 2002-09-11 테바 파마슈티컬 인더스트리즈 리미티드 클라리트로마이신 다형체 및 신규의 다형체 ⅳ의 제조 방법
HUP0204252A3 (en) * 2000-01-11 2003-04-28 Teva Pharma Process for preparing clarithromycin polymorphs and pharmaceutical compositions containing them
US6544555B2 (en) * 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
US6565882B2 (en) * 2000-02-24 2003-05-20 Advancis Pharmaceutical Corp Antibiotic composition with inhibitor
WO2001064224A1 (en) * 2000-02-29 2001-09-07 Teva Pharmaceutical Industries Ltd. Processes for preparing clarithromycin and clarithromycin intermediate, essentially oxime-free clarithromycin, and pharmaceutical composition comprising the same
MXPA02008861A (es) * 2000-03-15 2003-02-10 Hanmi Pharm Ind Co Ltd Metodo para preparar claritromicina de cristales de forma ii.
KR20000037126A (ko) * 2000-04-08 2000-07-05 김용규 6-메틸 에리스로마이신 a의 제조방법
US6541014B2 (en) * 2000-10-13 2003-04-01 Advancis Pharmaceutical Corp. Antiviral product, use and formulation thereof
US20020068078A1 (en) * 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
US20020197314A1 (en) * 2001-02-23 2002-12-26 Rudnic Edward M. Anti-fungal composition
AU2004258944B2 (en) * 2003-07-21 2011-02-10 Shionogi, Inc. Antibiotic product, use and formulation thereof
CA2533292C (en) * 2003-07-21 2013-12-31 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
AU2004258949B2 (en) * 2003-07-21 2011-02-10 Shionogi, Inc. Antibiotic product, use and formulation thereof
JP2007502296A (ja) * 2003-08-11 2007-02-08 アドバンシス ファーマスーティカル コーポレイション ロバストペレット
US8062672B2 (en) * 2003-08-12 2011-11-22 Shionogi Inc. Antibiotic product, use and formulation thereof
WO2005023184A2 (en) * 2003-08-29 2005-03-17 Advancis Pharmaceuticals Corporation Antibiotic product, use and formulation thereof
WO2005027877A1 (en) * 2003-09-15 2005-03-31 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
EP1701705A4 (en) * 2003-12-24 2007-08-08 Advancis Pharmaceutical Corp IMPROVED ABSORPTION OF MODIFIED RELEASE DOSAGE FORMS
WO2006014427A1 (en) * 2004-07-02 2006-02-09 Advancis Pharmaceutical Corporation Tablet for pulsed delivery
US7694523B2 (en) * 2004-07-19 2010-04-13 Earthrenew, Inc. Control system for gas turbine in material treatment unit
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
US8778924B2 (en) * 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
US8299052B2 (en) 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication
WO2009023191A2 (en) * 2007-08-09 2009-02-19 Teva Pharmaceutical Industries Ltd. An improved process for the preparation of clarithromycin

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4331803A (en) * 1980-06-04 1982-05-25 Taisho Pharmaceutical Co., Ltd. Novel erythromycin compounds
JPS60214796A (ja) * 1984-04-06 1985-10-28 Taisho Pharmaceut Co Ltd 6−0−メチルエリスロマイシン類の製法
JPS61103890A (ja) * 1984-10-26 1986-05-22 Taisho Pharmaceut Co Ltd 6−0−メチルエリスロマイシンa誘導体
US4670549A (en) * 1985-03-18 1987-06-02 Taisho Pharmaceutical Co., Ltd. Method for selective methylation of erythromycin a derivatives
JPS61229895A (ja) * 1985-04-03 1986-10-14 Nippon Zeon Co Ltd 保護化デス−n−メチルエリスロマイシン誘導体
EP0254534A3 (en) * 1986-07-24 1991-04-17 William S. Robinson Erythromycin derivatives and compositions and use for inhibiting virus replication and disease
DE3782994T2 (de) * 1986-09-18 1993-04-08 Taisho Pharma Co Ltd Erythromycin-a-derivate und verfahren zu ihrer herstellung.
KR960000434B1 (ko) * 1986-12-17 1996-01-06 다이쇼 세이야꾸 가부시끼가이샤 에리스로마이신 a유도체 및 그의 제조 방법
JP2751385B2 (ja) * 1988-05-19 1998-05-18 大正製薬株式会社 エリスロマイシンaオキシム及びその塩の製造方法

Also Published As

Publication number Publication date
EP0966477A1 (en) 1999-12-29
NO993876L (no) 1999-08-11
BG103673A (en) 2000-02-29
HUP0001330A2 (hu) 2000-08-28
SK97499A3 (en) 2000-01-18
CN1326865C (zh) 2007-07-18
CZ294481B6 (cs) 2005-01-12
BG64099B1 (bg) 2003-12-31
NZ336482A (en) 2001-02-23
JP2001512456A (ja) 2001-08-21
DE69818977T2 (de) 2004-08-12
PL187357B1 (pl) 2004-06-30
US5864023A (en) 1999-01-26
AU725274B2 (en) 2000-10-12
CA2279932C (en) 2008-04-22
CN1246864A (zh) 2000-03-08
PL335301A1 (en) 2000-04-10
NO993876D0 (no) 1999-08-11
PT966477E (pt) 2004-03-31
EP0966477B1 (en) 2003-10-15
ATE252108T1 (de) 2003-11-15
WO1998035976A1 (en) 1998-08-20
BR9807349A (pt) 2000-04-25
KR20000070985A (ko) 2000-11-25
DE69818977D1 (en) 2003-11-20
AR012032A1 (es) 2000-09-27
KR100561326B1 (ko) 2006-03-16
TR199901874T2 (xx) 2000-04-21
CA2279932A1 (en) 1998-08-20
ZA98986B (en) 1998-08-05
IL130697A0 (en) 2000-06-01
ES2212266T3 (es) 2004-07-16
SK284157B6 (sk) 2004-10-05
CZ270499A3 (cs) 1999-11-17
HUP0001330A3 (en) 2000-09-28
AU6260898A (en) 1998-09-08

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