ZA98986B - 3'-n-oxide,3'-N-dimethylamine, 9-oxime erythromycin A derivatives - Google Patents

3'-n-oxide,3'-N-dimethylamine, 9-oxime erythromycin A derivatives

Info

Publication number
ZA98986B
ZA98986B ZA98986A ZA98986A ZA98986B ZA 98986 B ZA98986 B ZA 98986B ZA 98986 A ZA98986 A ZA 98986A ZA 98986 A ZA98986 A ZA 98986A ZA 98986 B ZA98986 B ZA 98986B
Authority
ZA
South Africa
Prior art keywords
dimethylamine
derivatives
oxide
oxime erythromycin
erythromycin
Prior art date
Application number
ZA98986A
Other languages
English (en)
Inventor
Yi-Yin Ku
David A Riley
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of ZA98986B publication Critical patent/ZA98986B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA98986A 1997-02-13 1998-02-06 3'-n-oxide,3'-N-dimethylamine, 9-oxime erythromycin A derivatives ZA98986B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/800,009 US5864023A (en) 1997-02-13 1997-02-13 3'-N'oxide, 3'-n-dimethylamine, 9-oxime erythromycin a derivatives

Publications (1)

Publication Number Publication Date
ZA98986B true ZA98986B (en) 1998-08-05

Family

ID=25177295

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA98986A ZA98986B (en) 1997-02-13 1998-02-06 3'-n-oxide,3'-N-dimethylamine, 9-oxime erythromycin A derivatives

Country Status (25)

Country Link
US (1) US5864023A (xx)
EP (1) EP0966477B1 (xx)
JP (1) JP2001512456A (xx)
KR (1) KR100561326B1 (xx)
CN (1) CN1326865C (xx)
AR (1) AR012032A1 (xx)
AT (1) ATE252108T1 (xx)
AU (1) AU725274B2 (xx)
BG (1) BG64099B1 (xx)
BR (1) BR9807349A (xx)
CA (1) CA2279932C (xx)
CZ (1) CZ294481B6 (xx)
DE (1) DE69818977T2 (xx)
DK (1) DK0966477T3 (xx)
ES (1) ES2212266T3 (xx)
HU (1) HUP0001330A3 (xx)
IL (1) IL130697A0 (xx)
NO (1) NO993876L (xx)
NZ (1) NZ336482A (xx)
PL (1) PL187357B1 (xx)
PT (1) PT966477E (xx)
SK (1) SK284157B6 (xx)
TR (1) TR199901874T2 (xx)
WO (1) WO1998035976A1 (xx)
ZA (1) ZA98986B (xx)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100317907B1 (ko) * 1998-11-24 2001-12-24 김 완 주 신규한 중간체, 이를 이용한 마크로라이드계 항생제의제조방법
US6437106B1 (en) 1999-06-24 2002-08-20 Abbott Laboratories Process for preparing 6-o-substituted erythromycin derivatives
KR20010008496A (ko) * 1999-07-01 2001-02-05 유충식 6-오-메틸 에리트로마이신의 제조방법
KR100336447B1 (ko) * 1999-11-24 2002-05-15 민경윤 클라리스로마이신의 개선된 제조방법
IL150227A0 (en) * 1999-12-16 2002-12-01 Teva Pharma Processes for preparing clarithromycin polymorphs and novel polymorph iv
AU2261901A (en) * 2000-01-11 2001-07-24 Teva Pharma Processes for preparing clarithromycin polymorphs
US6565882B2 (en) * 2000-02-24 2003-05-20 Advancis Pharmaceutical Corp Antibiotic composition with inhibitor
US6544555B2 (en) 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
EP1313486A1 (en) 2000-02-29 2003-05-28 Teva Pharmaceutical Industries Ltd. Processes for preparing clarithromycin and clarithromycin intermediate, essentially oxime-free clarithromycin, and pharmaceutical composition comprising the same
BR0109194A (pt) * 2000-03-15 2003-02-11 Hanmi Pharm Ind Co Ltd Método para preparar claritromicina em cristais da forma ii
KR20000037126A (ko) * 2000-04-08 2000-07-05 김용규 6-메틸 에리스로마이신 a의 제조방법
US20020068078A1 (en) * 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
US6541014B2 (en) * 2000-10-13 2003-04-01 Advancis Pharmaceutical Corp. Antiviral product, use and formulation thereof
US20020197314A1 (en) * 2001-02-23 2002-12-26 Rudnic Edward M. Anti-fungal composition
JP2006528190A (ja) * 2003-07-21 2006-12-14 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
US8313776B2 (en) * 2003-07-21 2012-11-20 Shionogi Inc. Antibiotic product, use and formulation thereof
JP2006528185A (ja) * 2003-07-21 2006-12-14 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
CA2535177A1 (en) * 2003-08-11 2005-02-24 Advancis Pharmaceutical Corporation Robust pellet
CA2535398C (en) * 2003-08-12 2013-11-12 Advancis Pharmaceuticals Corporation Antibiotic product, use and formulation thereof
AU2004270170B2 (en) * 2003-08-29 2011-01-27 Shionogi, Inc. Antibiotic product, use and formulation thereof
WO2005027877A1 (en) * 2003-09-15 2005-03-31 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
CA2550983C (en) * 2003-12-24 2013-09-17 Advancis Pharmaceutical Corporation Enhanced absorption of modified release dosage forms
JP2008505124A (ja) * 2004-07-02 2008-02-21 アドバンシス ファーマスーティカル コーポレイション パルス送達用錠剤
US7694523B2 (en) * 2004-07-19 2010-04-13 Earthrenew, Inc. Control system for gas turbine in material treatment unit
US8778924B2 (en) * 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
US8299052B2 (en) 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication
WO2009023191A2 (en) * 2007-08-09 2009-02-19 Teva Pharmaceutical Industries Ltd. An improved process for the preparation of clarithromycin

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4331803A (en) * 1980-06-04 1982-05-25 Taisho Pharmaceutical Co., Ltd. Novel erythromycin compounds
JPS60214796A (ja) * 1984-04-06 1985-10-28 Taisho Pharmaceut Co Ltd 6−0−メチルエリスロマイシン類の製法
JPS61103890A (ja) * 1984-10-26 1986-05-22 Taisho Pharmaceut Co Ltd 6−0−メチルエリスロマイシンa誘導体
US4670549A (en) * 1985-03-18 1987-06-02 Taisho Pharmaceutical Co., Ltd. Method for selective methylation of erythromycin a derivatives
JPS61229895A (ja) * 1985-04-03 1986-10-14 Nippon Zeon Co Ltd 保護化デス−n−メチルエリスロマイシン誘導体
EP0254534A3 (en) * 1986-07-24 1991-04-17 William S. Robinson Erythromycin derivatives and compositions and use for inhibiting virus replication and disease
EP0260938B1 (en) * 1986-09-18 1992-12-09 Taisho Pharmaceutical Co. Ltd Erythromycin a derivatives and method for preparing the same
KR960000434B1 (ko) * 1986-12-17 1996-01-06 다이쇼 세이야꾸 가부시끼가이샤 에리스로마이신 a유도체 및 그의 제조 방법
JP2751385B2 (ja) * 1988-05-19 1998-05-18 大正製薬株式会社 エリスロマイシンaオキシム及びその塩の製造方法

Also Published As

Publication number Publication date
HUP0001330A3 (en) 2000-09-28
CN1246864A (zh) 2000-03-08
EP0966477A1 (en) 1999-12-29
PT966477E (pt) 2004-03-31
CZ294481B6 (cs) 2005-01-12
CA2279932A1 (en) 1998-08-20
EP0966477B1 (en) 2003-10-15
SK284157B6 (sk) 2004-10-05
KR100561326B1 (ko) 2006-03-16
CN1326865C (zh) 2007-07-18
BG103673A (en) 2000-02-29
AU6260898A (en) 1998-09-08
TR199901874T2 (xx) 2000-04-21
WO1998035976A1 (en) 1998-08-20
CZ270499A3 (cs) 1999-11-17
NO993876D0 (no) 1999-08-11
AR012032A1 (es) 2000-09-27
DE69818977D1 (en) 2003-11-20
KR20000070985A (ko) 2000-11-25
ES2212266T3 (es) 2004-07-16
DK0966477T3 (da) 2004-02-23
HUP0001330A2 (hu) 2000-08-28
BR9807349A (pt) 2000-04-25
CA2279932C (en) 2008-04-22
DE69818977T2 (de) 2004-08-12
AU725274B2 (en) 2000-10-12
PL187357B1 (pl) 2004-06-30
US5864023A (en) 1999-01-26
IL130697A0 (en) 2000-06-01
JP2001512456A (ja) 2001-08-21
PL335301A1 (en) 2000-04-10
NZ336482A (en) 2001-02-23
NO993876L (no) 1999-08-11
SK97499A3 (en) 2000-01-18
BG64099B1 (bg) 2003-12-31
ATE252108T1 (de) 2003-11-15

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