BG102312A - Производни на 5-о-деоаминил 6-о-метил еритронолида, и метод за получаването им - Google Patents

Производни на 5-о-деоаминил 6-о-метил еритронолида, и метод за получаването им

Info

Publication number
BG102312A
BG102312A BG102312A BG10231298A BG102312A BG 102312 A BG102312 A BG 102312A BG 102312 A BG102312 A BG 102312A BG 10231298 A BG10231298 A BG 10231298A BG 102312 A BG102312 A BG 102312A
Authority
BG
Bulgaria
Prior art keywords
oxy
preparation
deoaminyl
application
biologically active
Prior art date
Application number
BG102312A
Other languages
English (en)
Other versions
BG63822B1 (bg
Inventor
Alain Bonnet
Michel Delthil
Alain Mazurie
Original Assignee
Aventis Pharma S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9482423&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BG102312(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aventis Pharma S.A. filed Critical Aventis Pharma S.A.
Publication of BG102312A publication Critical patent/BG102312A/bg
Publication of BG63822B1 publication Critical patent/BG63822B1/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Изобретението се отнася до съединения, които могат да се използват за получаване на антибиотици. Теимат формула, в която OR1 и OR3 са хидроксилни групи, блокирани под формата на лесно отцепващи се радикали.
BG102312A 1995-09-11 1998-03-10 Производни на 5-о-деоаминил 6-о-метил еритронолида, и метод за получаването им BG63822B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9510601A FR2738571B1 (fr) 1995-09-11 1995-09-11 Nouveaux derives de la 5-0-desosaminyl 6-0-methyl- erythronolide a, leur procede de preparation et leur application a la preparation de produits biologiquement actifs
PCT/FR1996/001384 WO1997010251A1 (fr) 1995-09-11 1996-09-10 Nouveaux derives de la 5-0-desosaminyl 6-0-methyl erythronolide a, leur procede de preparation et leur application a la preparation de produits biologiquement actifs

Publications (2)

Publication Number Publication Date
BG102312A true BG102312A (bg) 1998-09-30
BG63822B1 BG63822B1 (bg) 2003-02-28

Family

ID=9482423

Family Applications (1)

Application Number Title Priority Date Filing Date
BG102312A BG63822B1 (bg) 1995-09-11 1998-03-10 Производни на 5-о-деоаминил 6-о-метил еритронолида, и метод за получаването им

Country Status (34)

Country Link
US (1) US5969161A (bg)
EP (1) EP0854880B1 (bg)
JP (1) JP4332218B2 (bg)
KR (1) KR100457755B1 (bg)
CN (2) CN1070498C (bg)
AP (1) AP887A (bg)
AR (1) AR004195A1 (bg)
AT (1) ATE266035T1 (bg)
AU (1) AU708811B2 (bg)
BG (1) BG63822B1 (bg)
BR (1) BR9610503A (bg)
CA (1) CA2228670C (bg)
CZ (3) CZ294865B6 (bg)
DE (1) DE69632405T2 (bg)
DK (1) DK0854880T3 (bg)
EA (1) EA000575B1 (bg)
EE (1) EE03774B1 (bg)
ES (1) ES2219698T3 (bg)
FR (1) FR2738571B1 (bg)
GE (1) GEP20022838B (bg)
HK (2) HK1016187A1 (bg)
HU (1) HU227565B1 (bg)
IL (1) IL123550A (bg)
MX (1) MX9801859A (bg)
NO (2) NO312678B1 (bg)
PL (1) PL183652B1 (bg)
PT (1) PT854880E (bg)
RO (1) RO120137B1 (bg)
SI (1) SI0854880T1 (bg)
SK (3) SK285853B6 (bg)
TR (1) TR199800438T1 (bg)
UA (1) UA53628C2 (bg)
WO (1) WO1997010251A1 (bg)
ZA (1) ZA966837B (bg)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL128681A0 (en) * 1996-09-04 2000-01-31 Abbott Lab 6-O substituted ketolides having antibacterial activity
UA51730C2 (uk) * 1996-09-04 2002-12-16 Ебботт Лабораторіз 6-o-заміщені кетоліди з антибактеріальною активністю, спосіб їх одержання (варіанти), фармацевтична композиція та спосіб регулювання бактеріальної інфекції у ссавців
US6034069A (en) * 1997-09-30 2000-03-07 Abbott Laboratories 3-'N-modified 6-O-substituted erythromycin ketolide derivatives having antibacterial activity
US6046171A (en) * 1997-10-29 2000-04-04 Abbott Laboratories 6,11-bridged erythromycin derivatives
US6124269A (en) * 1997-10-29 2000-09-26 Abbott Laboratories 2-Halo-6-O-substituted ketolide derivatives
US6054435A (en) * 1999-03-19 2000-04-25 Abbott Laboratories 6-O-substituted macrolides having antibacterial activity
US6420535B1 (en) 1999-06-07 2002-07-16 Abbott Laboratories 6-O-carbamate ketolide derivatives
CA2476423A1 (en) * 2002-02-15 2003-08-28 Sympore Gmbh Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof
US6841664B2 (en) * 2002-07-25 2005-01-11 Enanra Pharmaceuticals, Inc. 6,11-4-carbon bridged ketolides
US6764998B1 (en) 2003-06-18 2004-07-20 Enanta Pharmaceuticals, Inc. 6,11-4C-bicyclic 9a-azalide derivatives
US6753318B1 (en) * 2002-07-25 2004-06-22 Enanta Pharmaceuticals, Inc. 6,11-4-carbon bridged erythromycin derivatives
KR100661973B1 (ko) * 2002-05-13 2006-12-28 이난타 파마슈티칼스, 인코포레이티드 6,11 바이사이클릭 에리스로마이신 유도체
WO2005070918A1 (en) * 2002-05-13 2005-08-04 Enanta Pharmaceuticals, Inc. Process for the preparation of t-11 bicyclic erythromycin derivatives
US6878691B2 (en) * 2002-05-13 2005-04-12 Enanta Pharmaceuticals, Inc. 6-11 bicyclic ketolide derivatives
US7273853B2 (en) * 2002-05-13 2007-09-25 Enanta Pharmaceuticals, Inc. 6-11 bicyclic ketolide derivatives
US7135573B2 (en) * 2002-05-13 2006-11-14 Enanta Pharmaceuticals, Inc. Processes for the preparation of O-(6-Pyrazol-1-yl-pyridin-3-ylmethyl)-hydroxylamine
US7910558B2 (en) * 2002-05-13 2011-03-22 Enanta Pharmaceuticals, Inc. Bridged macrocyclic compounds and processes for the preparation thereof
US7064110B2 (en) * 2002-05-13 2006-06-20 Enanta Pharmaceuticals, Inc. 6-11 bicycle ketolide derivatives
ITMI20021726A1 (it) * 2002-08-01 2004-02-02 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
US6645941B1 (en) 2003-03-26 2003-11-11 Enanta Pharmaceuticals, Inc. 6,11-3C-bicyclic 9a-azalide derivatives
US7276487B2 (en) * 2003-09-23 2007-10-02 Enanta Pharmaceuticals, Inc. 9a, 11-3C-bicyclic 9a-azalide derivatives
US7414030B2 (en) * 2004-01-07 2008-08-19 Enanta Pharmaceuticals, Inc. 6-11 Bicyclic erythromycin derivatives
US7265094B2 (en) * 2004-01-09 2007-09-04 Enanta Pharmaceuticals, Inc. 9N-substituted 6-11 bicyclic erythromycin derivatives
JP2008522978A (ja) 2004-12-07 2008-07-03 エナンタ ファーマシューティカルズ インコーポレイテッド ３，６−ビシクロライド
US7229972B2 (en) 2004-12-07 2007-06-12 Enanta Pharmaceuticals, Inc. 3,6-Bicyclolides
WO2006065721A2 (en) 2004-12-13 2006-06-22 Enanta Pharmaceuticals, Inc. 11, 12-lactone bicyclolides
TW200635600A (en) 2004-12-13 2006-10-16 Enanta Pharm Inc Tetracyclic bicyclolides
US7384922B2 (en) * 2005-05-04 2008-06-10 Enanta Pharmaceuticals, Inc. 6-11 bridged oxime erythromycin derivatives
WO2007012464A1 (en) * 2005-07-26 2007-02-01 Merckle Gmbh Macrolide conjugates of pyrrolizine and indolizine compounds as inhibitors of 5-lipooxygenase and cyclooxygenase
US8273720B2 (en) * 2007-09-17 2012-09-25 Enanta Pharmaceuticals, Inc. 6,11-bicyclolides: bridged biaryl macrolide derivatives
US8354383B2 (en) * 2007-09-17 2013-01-15 Enanta Pharmaceuticals, Inc. 6,11-bridged biaryl macrolides
EP2203435B1 (en) * 2007-09-17 2018-07-18 Enanta Pharmaceuticals, Inc. 6, 11-bridged biaryl macrolides
CN103232501A (zh) * 2013-04-11 2013-08-07 宜昌东阳光药业股份有限公司 阿奇霉素或阿奇霉素的中间体脱去克拉定糖化合物的制备工艺

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR960000434B1 (ko) * 1986-12-17 1996-01-06 다이쇼 세이야꾸 가부시끼가이샤 에리스로마이신 a유도체 및 그의 제조 방법
US5523399A (en) * 1991-12-27 1996-06-04 Taisho Pharmaceutical Co., Ltd. 5-O-desosaminylerythronolide derivatives

Also Published As

Publication number Publication date
SI0854880T1 (en) 2004-12-31
BR9610503A (pt) 1999-07-06
CZ71798A3 (cs) 1998-07-15
ATE266035T1 (de) 2004-05-15
UA53628C2 (uk) 2003-02-17
JPH11512416A (ja) 1999-10-26
NO981053L (no) 1998-03-10
AP887A (en) 2000-11-10
CN1319602A (zh) 2001-10-31
NO981053D0 (no) 1998-03-10
CN1201462A (zh) 1998-12-09
AU708811B2 (en) 1999-08-12
SK283690B6 (sk) 2003-12-02
US5969161A (en) 1999-10-19
EA000575B1 (ru) 1999-12-29
NO20021111D0 (no) 2002-03-06
AU6991096A (en) 1997-04-01
FR2738571A1 (fr) 1997-03-14
CA2228670C (fr) 2005-04-12
HK1041489A1 (en) 2002-07-12
FR2738571B1 (fr) 1997-10-17
CZ294866B6 (cs) 2005-04-13
NO312678B1 (no) 2002-06-17
EE03774B1 (et) 2002-06-17
SK285853B6 (sk) 2007-09-06
KR100457755B1 (ko) 2005-02-28
NO315048B1 (no) 2003-06-30
EE9800065A (et) 1998-08-17
BG63822B1 (bg) 2003-02-28
PL326274A1 (en) 1998-08-31
SK29498A3 (en) 1998-12-02
ES2219698T3 (es) 2004-12-01
NO20021111L (no) 1998-03-10
CN1237069C (zh) 2006-01-18
RO120137B1 (ro) 2005-09-30
PL183652B1 (pl) 2002-06-28
DE69632405D1 (de) 2004-06-09
DK0854880T3 (da) 2004-08-16
EA199800288A1 (ru) 1998-08-27
ZA966837B (en) 1997-08-13
KR19990044543A (ko) 1999-06-25
HUP9802930A1 (hu) 1999-04-28
IL123550A (en) 2002-09-12
TR199800438T1 (xx) 1998-05-21
EP0854880B1 (fr) 2004-05-06
PT854880E (pt) 2004-09-30
HK1016187A1 (en) 1999-10-29
EP0854880A1 (fr) 1998-07-29
SK285995B6 (sk) 2008-01-07
JP4332218B2 (ja) 2009-09-16
MX9801859A (es) 1998-11-30
CN1070498C (zh) 2001-09-05
CZ289945B6 (cs) 2002-04-17
GEP20022838B (en) 2002-11-25
DE69632405T2 (de) 2005-05-19
CZ294865B6 (cs) 2005-04-13
AR004195A1 (es) 1998-11-04
WO1997010251A1 (fr) 1997-03-20
HU227565B1 (en) 2011-08-29
HUP9802930A3 (en) 1999-12-28
CA2228670A1 (fr) 1997-03-20
HK1041489B (zh) 2006-09-08
AP9801210A0 (en) 1998-03-31
IL123550A0 (en) 1998-10-30

Similar Documents

Publication Publication Date Title
BG102312A (bg) Производни на 5-о-деоаминил 6-о-метил еритронолида, и метод за получаването им
AU4821096A (en) Benzazepine-, benzoxazepine- and benzothiazepine-N-acetic derivatives, process for their preparation and pharmaceutical compositions containing them
HUP9603495A2 (en) 1-phenyl-2-dimethylaminomethyl-cyclohexan-1-ol-compounds, pharmaceutical compositions containing the same and process for their preparation
AU5278196A (en) New taxoids, their preparation and pharmaceutical compositions containing them
AU679663B2 (en) Dermatological or pharmaceutical composition, preparation process and use
AU1180997A (en) Novel taxoids, their preparation and pharmaceutical compositions containing them
AU1024897A (en) Mono-olefin/polyene interpolymers, method of preparation, compositions containing the same, and articles made thereof
HUP9601529A3 (en) Pyrimidinedion-, pyrimidinetrion-, triazinedion-, tetrahydro-quinazolinedion- derivatives, pharmaceutical compositions containing them, process for producing them and their use
AU6362796A (en) Substituted 4-phenylaminothiazoles, their process for preparation and the pharmaceutical compositions containing them
AU2481695A (en) Organometallic derivatives of group IIIA and process for their preparation
KR987000336A (en) Amphiphilic complexes, method for their preparation and compositions containing them
HUP9602635A3 (en) 4-aciloxy-benzenesulfonamide derivatives, process for their preparation and pharmaceutical compositions containing them
AU5254696A (en) Reduced toxicity compositions and methods for treating hiv infections
AU7220896A (en) New derivatives of 5-O-desosaminyl 6-O-methyl erythronolide A, their preparation process and their use in the preparation of biologically active products
ZA9610460B (en) New phenylamidine derivatives, processes for preparing them and their use as pharmaceutical compositions.
AU684430B2 (en) Chromone derivative, process for preparing same and pharmaceutical composition
IL141955A0 (en) Benzothiazolone derivatives, process for their preparation and pharmaceutical compositions containing them
HUP9803000A3 (en) Cyclopeptide derivatives, pharmaceutical compositions containing them, and process for producing them
HUP9601062A3 (en) Chromone derivatives, pharmaceutical compositions containing them and process for their preparation
AU5402896A (en) New taxoids, their preparation and pharmaceutical compositions containing same
AU3781793A (en) Process and compositions for dyeing hydrophobic polymer products
AU5639496A (en) Plant for producing groups of products
HUP9801068A3 (en) 1,2,3,4-tetrahydro-2-naphtaleneamine derivatives, process for their preparation, their use, and pharmaceutical compositions containing them
HUP9802571A3 (en) Pyridiniminyl-1,2-benzisoxazoles and- benzisothiazoles, process for their preparation and pharmaceutical compositions containing them
HUP9900079A3 (en) 12h-dibenzo[d,g][1,3]dioxocine derivatives, process for their preparation, their use and pharmaceutical compositions containing the same