BE901665A - Composition pharmaceutique a biodisponibilite elevee et procede pour la preparer. - Google Patents

Composition pharmaceutique a biodisponibilite elevee et procede pour la preparer.

Info

Publication number
BE901665A
BE901665A BE0/214459A BE214459A BE901665A BE 901665 A BE901665 A BE 901665A BE 0/214459 A BE0/214459 A BE 0/214459A BE 214459 A BE214459 A BE 214459A BE 901665 A BE901665 A BE 901665A
Authority
BE
Belgium
Prior art keywords
pharmaceutical composition
preparing
same
water
substance
Prior art date
Application number
BE0/214459A
Other languages
English (en)
Inventor
F Carli
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of BE901665A publication Critical patent/BE901665A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Un polymère gonflable à l'eau insoluble dans l'eau est chargé d'une substance biologiquement active ou d'une substance qui est convertie in vivo en substance biologiquement active, par exemple un médicament ou un précurseur de médicament, par préparation et broyage d'un mélange de ladite substance avec un polymère gonflable à l'eau insoluble dans l'eau dans un rapport des poids substance : polymère de 1 : 0,1 à 1 : 100 ; le polymère ainsi chargé est utilisable comme composition pharmaceutique.
BE0/214459A 1984-02-08 1985-02-06 Composition pharmaceutique a biodisponibilite elevee et procede pour la preparer. BE901665A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848403359A GB8403359D0 (en) 1984-02-08 1984-02-08 Pharmaceutical compositions

Publications (1)

Publication Number Publication Date
BE901665A true BE901665A (fr) 1985-08-06

Family

ID=10556299

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/214459A BE901665A (fr) 1984-02-08 1985-02-06 Composition pharmaceutique a biodisponibilite elevee et procede pour la preparer.

Country Status (7)

Country Link
US (1) US4639370A (fr)
JP (1) JPH0717496B2 (fr)
BE (1) BE901665A (fr)
DE (1) DE3503681A1 (fr)
FR (1) FR2559064B1 (fr)
GB (2) GB8403359D0 (fr)
IT (1) IT1221012B (fr)

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DE19608750A1 (de) * 1996-03-06 1997-09-11 Durachemie Gmbh & Co Kg Verfahren zur Herstellung von Fenofibrat-Präparaten
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DE10125509A1 (de) * 2001-05-23 2002-12-12 Hexal Ag Lösungsmittelfreie Homogenisatherstellung
AU2002321061B2 (en) * 2001-06-29 2006-08-24 Eurand Pharmaceuticals Ltd Process of thermodynamical activation of water-insoluble drugs loaded into cross linked polymers
GB2398221B (en) * 2001-10-26 2006-04-12 John Kohnke Dosage system & dosage vehicle therefor
ITMI20021074A1 (it) * 2002-05-20 2003-11-20 Actimex S R L Composizione ternaria comprendente una sostanza attiva e processo di comacinazione per la sua preparazione
AUPS244002A0 (en) * 2002-05-20 2002-06-13 John Kohnke Products Pty Ltd Agent delivery system
US20060193825A1 (en) * 2003-04-29 2006-08-31 Praecis Phamaceuticals, Inc. Pharmaceutical formulations for sustained drug delivery
US20050112087A1 (en) * 2003-04-29 2005-05-26 Musso Gary F. Pharmaceutical formulations for sustained drug delivery
MXPA05012632A (es) * 2003-05-20 2006-02-22 Ranbaxy Lab Ltd Composiciones farmaceuticas de acitretin.
AU2003304242A1 (en) * 2003-06-27 2005-01-13 Bioprogress S.P.A. Composite product obtainable by cogrinding of a active principle with a copolymer n-vinyl-2-pyrrolidone/vinyl-acetate
MY142989A (en) * 2004-03-10 2011-02-14 Bayer Schering Pharma Ag Stabilised supersaturated solids of lipophilic drugs
EP1730516A1 (fr) * 2004-03-30 2006-12-13 Pfizer Products Incorporated Procede et dispositif pour l'evaluation de compositions pharmaceutiques
WO2008065502A1 (fr) * 2006-11-29 2008-06-05 Pfizer Products Inc. Compositions pharmaceutiques constituées a) de nanoparticules comprenant des polymères entériques et b) de la caséine
US20100119612A1 (en) * 2007-04-17 2010-05-13 Bend Research, Inc Nanoparticles comprising non-crystalline drug
US20100080852A1 (en) * 2007-05-03 2010-04-01 Ronald Arthur Beyerinck Phamaceutical composition comprising nanoparticles and casein
US8703204B2 (en) * 2007-05-03 2014-04-22 Bend Research, Inc. Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and anon-ionizable polymer
WO2008135828A2 (fr) * 2007-05-03 2008-11-13 Pfizer Products Inc. Nanoparticules comprenant un médicament, de l'éthylcellulose et un sel biliaire
EP2162120B1 (fr) * 2007-06-04 2016-05-04 Bend Research, Inc Nanoparticules comportant un polymère cellulosique non ionisable et un copolymère bloc amphiphile non ionisable
WO2008149230A2 (fr) 2007-06-04 2008-12-11 Pfizer Products Inc. Nanoparticules comprenant un médicament, un polymère cellulosique non ionisable et du tocophéryl polyéthylène glycol succinate
EP2178518A2 (fr) * 2007-07-13 2010-04-28 Bend Research, Inc Nanoparticules comprenant des polymères cellulosiques ionisables faiblement solubles dans l'eau
US9233078B2 (en) * 2007-12-06 2016-01-12 Bend Research, Inc. Nanoparticles comprising a non-ionizable polymer and an Amine-functionalized methacrylate copolymer
WO2009073215A1 (fr) * 2007-12-06 2009-06-11 Bend Research, Inc. Compositions pharmaceutiques comprenant des nanoparticules et une matière de remise en suspension
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Also Published As

Publication number Publication date
GB8503034D0 (en) 1985-03-06
DE3503681C2 (fr) 1991-09-19
JPH0717496B2 (ja) 1995-03-01
GB8403359D0 (en) 1984-03-14
GB2153678B (en) 1988-04-13
DE3503681A1 (de) 1985-08-08
FR2559064A1 (fr) 1985-08-09
IT1221012B (it) 1990-06-21
GB2153678A (en) 1985-08-29
IT8519433A0 (it) 1985-02-07
US4639370A (en) 1987-01-27
JPS60181030A (ja) 1985-09-14
FR2559064B1 (fr) 1990-09-07

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Legal Events

Date Code Title Description
RE20 Patent expired

Owner name: *FARMITALIA CARLO ERBA S.R.L.

Effective date: 20050206

RE20 Patent expired

Owner name: *FARMITALIA CARLO ERBA S.R.L.

Effective date: 20050206