FR2559064B1 - Composition pharmaceutique a biodisponibilite elevee et procede pour la preparer - Google Patents

Composition pharmaceutique a biodisponibilite elevee et procede pour la preparer

Info

Publication number
FR2559064B1
FR2559064B1 FR858501561A FR8501561A FR2559064B1 FR 2559064 B1 FR2559064 B1 FR 2559064B1 FR 858501561 A FR858501561 A FR 858501561A FR 8501561 A FR8501561 A FR 8501561A FR 2559064 B1 FR2559064 B1 FR 2559064B1
Authority
FR
France
Prior art keywords
preparing
same
pharmaceutical composition
high bioavailability
bioavailability pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR858501561A
Other languages
English (en)
Other versions
FR2559064A1 (fr
Inventor
Fabio Carli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SRL
Publication of FR2559064A1 publication Critical patent/FR2559064A1/fr
Application granted granted Critical
Publication of FR2559064B1 publication Critical patent/FR2559064B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR858501561A 1984-02-08 1985-02-05 Composition pharmaceutique a biodisponibilite elevee et procede pour la preparer Expired - Lifetime FR2559064B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848403359A GB8403359D0 (en) 1984-02-08 1984-02-08 Pharmaceutical compositions

Publications (2)

Publication Number Publication Date
FR2559064A1 FR2559064A1 (fr) 1985-08-09
FR2559064B1 true FR2559064B1 (fr) 1990-09-07

Family

ID=10556299

Family Applications (1)

Application Number Title Priority Date Filing Date
FR858501561A Expired - Lifetime FR2559064B1 (fr) 1984-02-08 1985-02-05 Composition pharmaceutique a biodisponibilite elevee et procede pour la preparer

Country Status (7)

Country Link
US (1) US4639370A (fr)
JP (1) JPH0717496B2 (fr)
BE (1) BE901665A (fr)
DE (1) DE3503681A1 (fr)
FR (1) FR2559064B1 (fr)
GB (2) GB8403359D0 (fr)
IT (1) IT1221012B (fr)

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JPH0215027A (ja) * 1988-07-01 1990-01-18 Takada Seiyaku Kk 新規なプロブコール固形製剤
JPH0215026A (ja) * 1988-07-01 1990-01-18 Takada Seiyaku Kk 新規なプロブコール固形製剤
IT1227626B (it) * 1988-11-28 1991-04-23 Vectorpharma Int Farmaci supportati aventi velocita' di dissoluzione aumentata e procedimento per la loro preparazione
IT1241417B (it) 1990-03-06 1994-01-14 Vectorpharma Int Composizioni terapeutiche a rilascio controllato di farmaci supportatisu polimeri reticolati e rivestiti con film polimerici,e loro processodi preparazione
IT1246188B (it) * 1990-07-27 1994-11-16 Resa Farma Procedimento per la preparazione di composizioni farmaceutiche aventi aumentata velocita' di dissoluzione della sostanza attiva e composizioni ottenute.
JP2516524B2 (ja) * 1992-04-27 1996-07-24 大洋薬品工業株式会社 持続性製剤
US5252611A (en) * 1992-07-20 1993-10-12 Isp Investments Inc. Controlled release tablets including strongly swellable, moderately crosslinked polyvinylpyrrolidone
IT1256386B (it) * 1992-11-13 1995-12-04 Luigi Boltri Composizioni farmaceutiche comprendenti un farmaco,una sostanza polimerica reticolata,un olio ed un agente tensioattivo
CA2218486A1 (fr) * 1995-04-20 1996-10-24 Vectorpharma - Eon N.A. Compose contenant du glycolate d'amidon de sodium en tant que materiau support et produits a base de ce compose
ATE208631T1 (de) * 1996-02-05 2001-11-15 Sankyo Co 5-alpha reductase inhibierende zusammenstellung zur oralen verabreichung, verfahren zur herstellung und deren verwendung
DE19608750A1 (de) * 1996-03-06 1997-09-11 Durachemie Gmbh & Co Kg Verfahren zur Herstellung von Fenofibrat-Präparaten
US5968895A (en) * 1996-12-11 1999-10-19 Praecis Pharmaceuticals, Inc. Pharmaceutical formulations for sustained drug delivery
US20070185032A1 (en) * 1996-12-11 2007-08-09 Praecis Pharmaceuticals, Inc. Pharmaceutical formulations for sustained drug delivery
UA65607C2 (uk) 1998-03-04 2004-04-15 Орто-Макнейл Фармацевтикал, Інк. Фармацевтична композиція (варіанти) та спосіб її приготування
US20020132839A1 (en) * 2000-06-22 2002-09-19 Ganter Sabina Maria Tablet formulations comprising valsartan
JP2004506670A (ja) 2000-08-21 2004-03-04 ユニリーバー・ナームローゼ・ベンノートシヤープ 活性成分と混合粉砕した担体を含む水性練り歯磨
DE10125509A1 (de) * 2001-05-23 2002-12-12 Hexal Ag Lösungsmittelfreie Homogenisatherstellung
ES2295379T3 (es) * 2001-06-29 2008-04-16 Eurand Pharmaceuticals Ltd. Procedimiento de activacion termodinamica de medicamentos insolubles en agua cargados en polimeros reticulados.
WO2003034837A1 (fr) * 2001-10-26 2003-05-01 John Kohnke Products Pty Ltd Systeme de forme galenique et vehicule utilise a cet effet
AUPS244002A0 (en) * 2002-05-20 2002-06-13 John Kohnke Products Pty Ltd Agent delivery system
ITMI20021074A1 (it) * 2002-05-20 2003-11-20 Actimex S R L Composizione ternaria comprendente una sostanza attiva e processo di comacinazione per la sua preparazione
US20050112087A1 (en) * 2003-04-29 2005-05-26 Musso Gary F. Pharmaceutical formulations for sustained drug delivery
US20060193825A1 (en) * 2003-04-29 2006-08-31 Praecis Phamaceuticals, Inc. Pharmaceutical formulations for sustained drug delivery
MXPA05012632A (es) * 2003-05-20 2006-02-22 Ranbaxy Lab Ltd Composiciones farmaceuticas de acitretin.
DE60309356T2 (de) * 2003-06-27 2007-08-30 Bioprogress S.P.A. Zusammensetzung, durch zusammen vermahlen eines wirkstoffes mit einem n-vinyl-2-pyrrolidon/vinylacetatkopolymers erhältlich
MY142989A (en) * 2004-03-10 2011-02-14 Bayer Schering Pharma Ag Stabilised supersaturated solids of lipophilic drugs
WO2005095950A1 (fr) * 2004-03-30 2005-10-13 Pfizer Products Inc. Procede et dispositif pour l'evaluation de compositions pharmaceutiques
US20100062073A1 (en) * 2006-11-29 2010-03-11 Ronald Arthur Beyerinck Pharmaceutical compositions comprising nanoparticles comprising enteric polymers casein
US20100119612A1 (en) * 2007-04-17 2010-05-13 Bend Research, Inc Nanoparticles comprising non-crystalline drug
WO2008135852A2 (fr) * 2007-05-03 2008-11-13 Pfizer Products Inc. Compositions pharmaceutiques comprenant des nanoparticules et de la caséine
WO2008135828A2 (fr) * 2007-05-03 2008-11-13 Pfizer Products Inc. Nanoparticules comprenant un médicament, de l'éthylcellulose et un sel biliaire
US8703204B2 (en) * 2007-05-03 2014-04-22 Bend Research, Inc. Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and anon-ionizable polymer
WO2008149230A2 (fr) 2007-06-04 2008-12-11 Pfizer Products Inc. Nanoparticules comprenant un médicament, un polymère cellulosique non ionisable et du tocophéryl polyéthylène glycol succinate
WO2008149192A2 (fr) * 2007-06-04 2008-12-11 Pfizer Products Inc. Nanoparticules comportant un polymère cellulosique non ionisable et un copolymère bloc amphiphile non ionisable
WO2009010842A2 (fr) * 2007-07-13 2009-01-22 Pfizer Products Inc. Nanoparticules comprenant des polymères cellulosiques ionisables faiblement solubles dans l'eau
US9724362B2 (en) * 2007-12-06 2017-08-08 Bend Research, Inc. Pharmaceutical compositions comprising nanoparticles and a resuspending material
US9233078B2 (en) * 2007-12-06 2016-01-12 Bend Research, Inc. Nanoparticles comprising a non-ionizable polymer and an Amine-functionalized methacrylate copolymer
CA2759125C (fr) * 2009-04-24 2017-08-15 Iceutica Pty Ltd Nouvelle formulation d'indomethacine
JP5530716B2 (ja) * 2009-12-28 2014-06-25 ライオン株式会社 生薬含有錠剤、生薬含有錠剤用の生薬担持粒子の製造方法
ITMI20120092A1 (it) 2012-01-26 2013-07-27 Micro Macinazione S A Compositi di inclusione farmaco-carrier preparati con processo di attivazione meccano-chimica mediante mulini a getto di fluido ad alta energia

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GB426290A (en) * 1933-03-08 1935-04-01 Heyden Chem Fab Manufacture of preparations having an anti-emetic action
DE2200778B2 (de) * 1971-01-13 1974-04-18 Sandoz Ag, Basel (Schweiz) Verwendung von hochmolekularem, unlöslichem, quervernetztem Polyvinylpyrrolidon als Sprengmittel in festen Arzneiformen
JPS5132719A (en) * 1974-09-13 1976-03-19 Yoshinobu Nakai Iyakuhinnoshorihoho
DE2634004B2 (de) * 1976-07-29 1978-08-10 Bernhard Dr. 8000 Muenchen Lippold Verfahren zur Beschleunigung der Auflösung und Verbesserung der Löslichkeit von schlechtlöslichen zur peroralen Verabreichung bestimmten Arzneistoffen
CA1098443A (fr) * 1977-05-20 1981-03-31 Namassivaya Doddi Composes medicinal absorbable contenant des polymeres de p-dioxanone
JPS603783B2 (ja) * 1977-08-10 1985-01-30 株式会社日立製作所 共通リードフレームから小リード数のリードフレームを製造する方法
GB1601833A (en) * 1978-02-06 1981-11-04 Wellcome Found Antacid formulation
GB2042888B (en) * 1979-03-05 1983-09-28 Teijin Ltd Preparation for administration to the mucosa of the oral or nasal cavity
IT1131833B (it) * 1980-06-20 1986-06-25 Crinos Industria Farmaco Eccipienti per sostanze spermicide
JPS6029682B2 (ja) * 1980-07-11 1985-07-12 山之内製薬株式会社 苦味のない製剤用組成物およびその製造法
DE3045135A1 (de) * 1980-11-29 1982-06-09 Sandoz-Patent-GmbH, 7850 Lörrach Pharmazeutische kompositionen enthaltende bioabbaubare polymere
IL61721A (en) * 1980-12-16 1984-03-30 Blank Izhak Nitroglycerin preparations
EP0078430B2 (fr) * 1981-10-29 1993-02-10 Bayer Ag Procédé de fabrication de préparations pharmaceutiques solides à libération rapide de dihydropyridines
JPS59101422A (ja) * 1982-12-02 1984-06-12 Takada Seiyaku Kk 溶出性の優れたニフエジピン固形製剤
EP0129893B1 (fr) * 1983-06-28 1991-09-04 Takeda Chemical Industries, Ltd. Mélange broyé
US4555399A (en) * 1983-11-18 1985-11-26 Key Pharmaceuticals, Inc. Aspirin tablet

Also Published As

Publication number Publication date
GB8403359D0 (en) 1984-03-14
DE3503681C2 (fr) 1991-09-19
US4639370A (en) 1987-01-27
GB8503034D0 (en) 1985-03-06
FR2559064A1 (fr) 1985-08-09
DE3503681A1 (de) 1985-08-08
JPH0717496B2 (ja) 1995-03-01
GB2153678B (en) 1988-04-13
IT1221012B (it) 1990-06-21
IT8519433A0 (it) 1985-02-07
GB2153678A (en) 1985-08-29
JPS60181030A (ja) 1985-09-14
BE901665A (fr) 1985-08-06

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Legal Events

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TP Transmission of property