ES8801276A1 - Procedimiento para preparar nuevos derivados imidazo - Google Patents
Procedimiento para preparar nuevos derivados imidazoInfo
- Publication number
- ES8801276A1 ES8801276A1 ES556974A ES556974A ES8801276A1 ES 8801276 A1 ES8801276 A1 ES 8801276A1 ES 556974 A ES556974 A ES 556974A ES 556974 A ES556974 A ES 556974A ES 8801276 A1 ES8801276 A1 ES 8801276A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- medicines containing
- imidazo derivatives
- derivatives
- imidazo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Cardiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE IMIDAZO, DE SUS SALES DE ADICION DE ACIDOS, DE FORMULA (I). COMPRENDE LA REACCION DE UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA R4SO2Y, PARA OBTENER UN COMPUESTO DE FORMULA (I), EN LAS QUE A, B, C Y D REPRESENTAN NITROGENO, METINO O METINO SUSTITUIDO, Y R1, R2, R3, R''1, R''2, Y R''3 PUEDEN SER VARIOS TIPOS DE RADICALES. LA REACCION SE EFECTUA EN UN DISOLVENTE INERTE, EN PRESENCIA DE UN ACEPTOR DE ACIDOS, A UNA TEMPERATURA COMPRENDIDA ENTRE 0JC Y 100JC. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SUS PROPIEDADES ANTITROMBOTICOS Y CARDIOVASCULARES Y SUS EFECTOS CARDIOTONICOS Y SOBRE LA PRESION SANGUINEA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19843446778 DE3446778A1 (de) | 1984-12-21 | 1984-12-21 | Neue imidazoderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8801276A1 true ES8801276A1 (es) | 1988-01-01 |
ES556974A0 ES556974A0 (es) | 1988-01-01 |
Family
ID=6253488
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES550241A Expired ES8703472A1 (es) | 1984-12-21 | 1985-12-20 | Procedimiento para preparar nuevos derivados imidazo |
ES556974A Expired ES8801276A1 (es) | 1984-12-21 | 1986-07-23 | Procedimiento para preparar nuevos derivados imidazo |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES550241A Expired ES8703472A1 (es) | 1984-12-21 | 1985-12-20 | Procedimiento para preparar nuevos derivados imidazo |
Country Status (14)
Country | Link |
---|---|
US (1) | US4716169A (es) |
EP (1) | EP0185345A1 (es) |
JP (1) | JPS61152681A (es) |
AU (1) | AU5154585A (es) |
DD (1) | DD242407A5 (es) |
DE (1) | DE3446778A1 (es) |
DK (1) | DK590185A (es) |
ES (2) | ES8703472A1 (es) |
FI (1) | FI855080A (es) |
GR (1) | GR853124B (es) |
HU (1) | HU194562B (es) |
NO (1) | NO855196L (es) |
PT (1) | PT81716B (es) |
ZA (1) | ZA859729B (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4833149A (en) * | 1986-09-22 | 1989-05-23 | Ortho Pharmaceutical Corporation | 2- or 3-aryl substituted imidazo[1,2-a]pyridines |
GB8719368D0 (en) * | 1987-08-15 | 1987-09-23 | Wellcome Found | Heterocyclic compounds |
SE8704248D0 (sv) * | 1987-10-30 | 1987-10-30 | Haessle Ab | Medical use |
EP0471236B1 (en) * | 1990-07-30 | 1995-03-15 | Takeda Chemical Industries, Ltd. | Imidazopyridine derivatives and their use |
US6127576A (en) * | 1996-12-20 | 2000-10-03 | American Cyanamid Company | Aminophenyl ketone derivatives and a method for the preparation thereof |
JP4327915B2 (ja) * | 1998-03-30 | 2009-09-09 | 株式会社デ・ウエスタン・セラピテクス研究所 | スルフォンアミド誘導体 |
US6596731B2 (en) | 2001-03-27 | 2003-07-22 | Hoffmann-La Roche Inc. | Substituted imidazo[1,2-A] pyridine derivatives |
US20080219922A1 (en) * | 2005-09-12 | 2008-09-11 | Goodman Mark M | Alzheimer's Disease Imaging Agents |
US7723336B2 (en) * | 2005-09-22 | 2010-05-25 | Bristol-Myers Squibb Company | Fused heterocyclic compounds useful as kinase modulators |
US8703096B2 (en) * | 2006-04-21 | 2014-04-22 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Beta-amyloid PET imaging agents |
EP1964841A1 (en) * | 2007-02-28 | 2008-09-03 | sanofi-aventis | Imidazo[1,2-a]azine and their use as pharmaceuticals |
EP1964840A1 (en) * | 2007-02-28 | 2008-09-03 | sanofi-aventis | Imidazo[1,2-a]pyridines and their use as pharmaceuticals |
US7868001B2 (en) | 2007-11-02 | 2011-01-11 | Hutchison Medipharma Enterprises Limited | Cytokine inhibitors |
EP2240488B1 (en) * | 2008-02-06 | 2016-11-02 | Bristol-Myers Squibb Company | Substituted imidazopyridazines useful as kinase inhibitors |
US20110065728A1 (en) * | 2008-05-14 | 2011-03-17 | Otsuka Pharmaceutical Factory, Inc. | Lipoprotein lipase-activating compositions comprising benzene derivatives |
PL2841437T3 (pl) * | 2012-04-26 | 2017-12-29 | Bristol-Myers Squibb Company | Pochodne imidazotiadiazolu i imidazopirazyny jako inhibitory receptora 4 (par4) aktywowanego proteazą do leczenia agregacji płytek |
EP2855489B1 (en) * | 2012-04-26 | 2017-01-04 | Bristol-Myers Squibb Company | Imidazothiadiazole and imidazopyridazine derivatives as protease activated receptor 4 (par4) inhibitors for treating platelet aggregation |
EP2847200B1 (en) | 2012-04-26 | 2017-03-29 | Bristol-Myers Squibb Company | Imidazothiadiazole derivatives as protease activated receptor 4 (par4) inhibitors for treating platelet aggregation |
US9598419B1 (en) | 2014-06-24 | 2017-03-21 | Universite De Montreal | Imidazotriazine and imidazodiazine compounds |
US9617279B1 (en) | 2014-06-24 | 2017-04-11 | Bristol-Myers Squibb Company | Imidazooxadiazole compounds |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS523957B2 (es) * | 1974-03-14 | 1977-01-31 | ||
US4166851A (en) * | 1977-05-16 | 1979-09-04 | Merck & Co., Inc. | Certain imidazo(1,2a)pyridine derivatives |
RO87859B (ro) * | 1982-12-27 | 1985-12-31 | Eli Lilly And Company | Procedeu pentru prepararea unor derivati de inidazopirimidina pirezina si triazina |
-
1984
- 1984-12-21 DE DE19843446778 patent/DE3446778A1/de not_active Withdrawn
-
1985
- 1985-12-16 EP EP85116025A patent/EP0185345A1/de not_active Withdrawn
- 1985-12-17 US US06/810,008 patent/US4716169A/en not_active Expired - Fee Related
- 1985-12-17 DD DD85284542A patent/DD242407A5/de unknown
- 1985-12-18 DK DK590185A patent/DK590185A/da not_active Application Discontinuation
- 1985-12-19 FI FI855080A patent/FI855080A/fi not_active Application Discontinuation
- 1985-12-19 PT PT81716A patent/PT81716B/pt unknown
- 1985-12-20 HU HU854933A patent/HU194562B/hu unknown
- 1985-12-20 JP JP60287602A patent/JPS61152681A/ja active Pending
- 1985-12-20 AU AU51545/85A patent/AU5154585A/en not_active Abandoned
- 1985-12-20 ES ES550241A patent/ES8703472A1/es not_active Expired
- 1985-12-20 ZA ZA859729A patent/ZA859729B/xx unknown
- 1985-12-20 NO NO855196A patent/NO855196L/no unknown
- 1985-12-20 GR GR853124A patent/GR853124B/el unknown
-
1986
- 1986-07-23 ES ES556974A patent/ES8801276A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
GR853124B (es) | 1986-04-22 |
DD242407A5 (de) | 1987-01-28 |
PT81716B (de) | 1987-10-15 |
US4716169A (en) | 1987-12-29 |
DK590185D0 (da) | 1985-12-18 |
JPS61152681A (ja) | 1986-07-11 |
ES550241A0 (es) | 1987-02-16 |
HU194562B (en) | 1988-02-29 |
AU5154585A (en) | 1986-06-26 |
FI855080A (fi) | 1986-06-22 |
NO855196L (no) | 1986-06-23 |
HUT40434A (en) | 1986-12-28 |
DK590185A (da) | 1986-06-22 |
ES556974A0 (es) | 1988-01-01 |
ES8703472A1 (es) | 1987-02-16 |
EP0185345A1 (de) | 1986-06-25 |
FI855080A0 (fi) | 1985-12-19 |
PT81716A (de) | 1986-01-01 |
ZA859729B (en) | 1987-08-26 |
DE3446778A1 (de) | 1986-07-03 |
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