ZA859729B - New imidazo derivatives,the preparation thereof and pharmaceutical compositions containing these compounds - Google Patents

New imidazo derivatives,the preparation thereof and pharmaceutical compositions containing these compounds

Info

Publication number
ZA859729B
ZA859729B ZA859729A ZA859729A ZA859729B ZA 859729 B ZA859729 B ZA 859729B ZA 859729 A ZA859729 A ZA 859729A ZA 859729 A ZA859729 A ZA 859729A ZA 859729 B ZA859729 B ZA 859729B
Authority
ZA
South Africa
Prior art keywords
compounds
preparation
pharmaceutical compositions
compositions containing
new imidazo
Prior art date
Application number
ZA859729A
Other languages
English (en)
Inventor
Joachim Heider
Norbert Hauel
Volkhard Austel
Klaus Noll
Andreas Bomhard
Jacques Van Mell
Willi Diederen
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of ZA859729B publication Critical patent/ZA859729B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA859729A 1984-12-21 1985-12-20 New imidazo derivatives,the preparation thereof and pharmaceutical compositions containing these compounds ZA859729B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843446778 DE3446778A1 (de) 1984-12-21 1984-12-21 Neue imidazoderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
ZA859729B true ZA859729B (en) 1987-08-26

Family

ID=6253488

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA859729A ZA859729B (en) 1984-12-21 1985-12-20 New imidazo derivatives,the preparation thereof and pharmaceutical compositions containing these compounds

Country Status (14)

Country Link
US (1) US4716169A (es)
EP (1) EP0185345A1 (es)
JP (1) JPS61152681A (es)
AU (1) AU5154585A (es)
DD (1) DD242407A5 (es)
DE (1) DE3446778A1 (es)
DK (1) DK590185A (es)
ES (2) ES8703472A1 (es)
FI (1) FI855080A (es)
GR (1) GR853124B (es)
HU (1) HU194562B (es)
NO (1) NO855196L (es)
PT (1) PT81716B (es)
ZA (1) ZA859729B (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4833149A (en) * 1986-09-22 1989-05-23 Ortho Pharmaceutical Corporation 2- or 3-aryl substituted imidazo[1,2-a]pyridines
GB8719368D0 (en) * 1987-08-15 1987-09-23 Wellcome Found Heterocyclic compounds
SE8704248D0 (sv) * 1987-10-30 1987-10-30 Haessle Ab Medical use
EP0471236B1 (en) * 1990-07-30 1995-03-15 Takeda Chemical Industries, Ltd. Imidazopyridine derivatives and their use
US6127576A (en) * 1996-12-20 2000-10-03 American Cyanamid Company Aminophenyl ketone derivatives and a method for the preparation thereof
JP4327915B2 (ja) * 1998-03-30 2009-09-09 株式会社デ・ウエスタン・セラピテクス研究所 スルフォンアミド誘導体
US6596731B2 (en) 2001-03-27 2003-07-22 Hoffmann-La Roche Inc. Substituted imidazo[1,2-A] pyridine derivatives
WO2007033080A2 (en) * 2005-09-12 2007-03-22 Emory University Alzheimer's disease imaging agents
US7723336B2 (en) * 2005-09-22 2010-05-25 Bristol-Myers Squibb Company Fused heterocyclic compounds useful as kinase modulators
EP2021340B1 (en) * 2006-04-21 2014-07-23 The Government Of The United States, As Represented by The Secretary Of Health And Human Services Beta-amyloid pet imaging agents
EP1964841A1 (en) * 2007-02-28 2008-09-03 sanofi-aventis Imidazo[1,2-a]azine and their use as pharmaceuticals
EP1964840A1 (en) * 2007-02-28 2008-09-03 sanofi-aventis Imidazo[1,2-a]pyridines and their use as pharmaceuticals
US7868001B2 (en) 2007-11-02 2011-01-11 Hutchison Medipharma Enterprises Limited Cytokine inhibitors
JP5394404B2 (ja) * 2008-02-06 2014-01-22 ブリストル−マイヤーズ スクイブ カンパニー キナーゼ阻害剤として有用な置換イミダゾピリダジン類
EP2280706B1 (en) * 2008-05-14 2013-01-02 Otsuka Pharmaceutical Factory, Inc. Lipoprotein lipase-activating compositions comprising benzene derivatives
JP6101343B2 (ja) * 2012-04-26 2017-03-22 ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company 血小板凝集を治療するためのプロテアーゼ活性化受容体4(par4)阻害剤としてのイミダゾチアジアゾールおよびイミダゾピリダジン誘導体
CN104540835B (zh) 2012-04-26 2017-08-08 百时美施贵宝公司 用于治疗血小板聚集的作为蛋白酶激活受体4(par4)抑制剂的咪唑并噻二唑衍生物
HUE060743T2 (hu) * 2012-04-26 2023-04-28 Bristol Myers Squibb Co Gyógyszerészeti kompozíciók, amelyek tartalmaznak imidazothiadiazol- és imidazopiridazinszármazékokat mint proteáz aktívált receptor 4 (PAR4) inhibitorokat trombocitaaggregációk kezelésére
US9598419B1 (en) 2014-06-24 2017-03-21 Universite De Montreal Imidazotriazine and imidazodiazine compounds
US9617279B1 (en) 2014-06-24 2017-04-11 Bristol-Myers Squibb Company Imidazooxadiazole compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS523957B2 (es) * 1974-03-14 1977-01-31
US4166851A (en) * 1977-05-16 1979-09-04 Merck & Co., Inc. Certain imidazo(1,2a)pyridine derivatives
PT77844B (en) * 1982-12-27 1986-05-08 Lilly Co Eli Process for preparing substituted imidazopyrimidines -pyrazines and -triazines

Also Published As

Publication number Publication date
EP0185345A1 (de) 1986-06-25
FI855080A (fi) 1986-06-22
PT81716B (de) 1987-10-15
HU194562B (en) 1988-02-29
NO855196L (no) 1986-06-23
ES8703472A1 (es) 1987-02-16
US4716169A (en) 1987-12-29
FI855080A0 (fi) 1985-12-19
ES550241A0 (es) 1987-02-16
AU5154585A (en) 1986-06-26
ES8801276A1 (es) 1988-01-01
HUT40434A (en) 1986-12-28
DK590185D0 (da) 1985-12-18
GR853124B (es) 1986-04-22
ES556974A0 (es) 1988-01-01
PT81716A (de) 1986-01-01
DE3446778A1 (de) 1986-07-03
DD242407A5 (de) 1987-01-28
DK590185A (da) 1986-06-22
JPS61152681A (ja) 1986-07-11

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