AU2016331918B2 - Crystal forms of β-nicotinamide mononucleotide - Google Patents

Crystal forms of β-nicotinamide mononucleotide Download PDF

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Publication number
AU2016331918B2
AU2016331918B2 AU2016331918A AU2016331918A AU2016331918B2 AU 2016331918 B2 AU2016331918 B2 AU 2016331918B2 AU 2016331918 A AU2016331918 A AU 2016331918A AU 2016331918 A AU2016331918 A AU 2016331918A AU 2016331918 B2 AU2016331918 B2 AU 2016331918B2
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compound
crystalline form
crystalline
composition
formula
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AU2016331918A1 (en
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Andrew Carr
Philippe Fernandes
David J. Livingston
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Metro International Biotech LLC
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Metro International Biotech LLC
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/048—Pyridine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AU2016331918A 2015-10-02 2016-09-30 Crystal forms of β-nicotinamide mononucleotide Active AU2016331918B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562236657P 2015-10-02 2015-10-02
US62/236,657 2015-10-02
PCT/US2016/054776 WO2017059249A1 (en) 2015-10-02 2016-09-30 Crystal forms of beta-nicotinamide mononucleotide

Publications (2)

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AU2016331918A1 AU2016331918A1 (en) 2018-05-10
AU2016331918B2 true AU2016331918B2 (en) 2021-11-04

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US (6) US10392415B2 (enExample)
EP (2) EP3355895A4 (enExample)
JP (4) JP2018534265A (enExample)
KR (1) KR102779733B1 (enExample)
CN (1) CN108697722B (enExample)
AU (1) AU2016331918B2 (enExample)
BR (1) BR112018006243A2 (enExample)
CA (1) CA3000744C (enExample)
EA (1) EA037104B1 (enExample)
GB (1) GB2542881B (enExample)
IL (1) IL258276B (enExample)
MX (1) MX390064B (enExample)
WO (1) WO2017059249A1 (enExample)
ZA (1) ZA201802657B (enExample)

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