BR112018006243A2 - formas de cristal de mononucleotídeo de beta-nicotinamida - Google Patents

formas de cristal de mononucleotídeo de beta-nicotinamida

Info

Publication number
BR112018006243A2
BR112018006243A2 BR112018006243-0A BR112018006243A BR112018006243A2 BR 112018006243 A2 BR112018006243 A2 BR 112018006243A2 BR 112018006243 A BR112018006243 A BR 112018006243A BR 112018006243 A2 BR112018006243 A2 BR 112018006243A2
Authority
BR
Brazil
Prior art keywords
beta
crystal forms
nicotinamide mononucleotide
mononucleotide
nicotinamide
Prior art date
Application number
BR112018006243-0A
Other languages
English (en)
Inventor
Carr Andrew
Fernandes Phillippe
J. Livingston David
Original Assignee
Metro International Biotech, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metro International Biotech, Llc filed Critical Metro International Biotech, Llc
Publication of BR112018006243A2 publication Critical patent/BR112018006243A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/048—Pyridine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

a presente invenção refere-se a formas cristalinas de um ß-mononucleotídeo de nicotinamida, métodos para sua preparação e suas preparações farmacêuticas relacionadas. a invenção também refere-se a preparações adequadas para usos nutracêuticos, veterinários e agricolamente relevantes.
BR112018006243-0A 2015-10-02 2016-09-30 formas de cristal de mononucleotídeo de beta-nicotinamida BR112018006243A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562236657P 2015-10-02 2015-10-02
US62/236,657 2015-10-02
PCT/US2016/054776 WO2017059249A1 (en) 2015-10-02 2016-09-30 Crystal forms of beta-nicotinamide mononucleotide

Publications (1)

Publication Number Publication Date
BR112018006243A2 true BR112018006243A2 (pt) 2018-10-16

Family

ID=56320606

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112018006243-0A BR112018006243A2 (pt) 2015-10-02 2016-09-30 formas de cristal de mononucleotídeo de beta-nicotinamida

Country Status (14)

Country Link
US (5) US10392415B2 (pt)
EP (2) EP4272746A3 (pt)
JP (3) JP2018534265A (pt)
KR (1) KR20180073582A (pt)
CN (1) CN108697722B (pt)
AU (1) AU2016331918B2 (pt)
BR (1) BR112018006243A2 (pt)
CA (1) CA3000744C (pt)
EA (1) EA037104B1 (pt)
GB (1) GB2542881B (pt)
IL (1) IL258276B (pt)
MX (1) MX2018003656A (pt)
WO (1) WO2017059249A1 (pt)
ZA (1) ZA201802657B (pt)

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