AU2003240481B8 - Methods and materials for the production of D-lactic acid in yeast - Google Patents

Methods and materials for the production of D-lactic acid in yeast Download PDF

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Publication number
AU2003240481B8
AU2003240481B8 AU2003240481A AU2003240481A AU2003240481B8 AU 2003240481 B8 AU2003240481 B8 AU 2003240481B8 AU 2003240481 A AU2003240481 A AU 2003240481A AU 2003240481 A AU2003240481 A AU 2003240481A AU 2003240481 B8 AU2003240481 B8 AU 2003240481B8
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Prior art keywords
cell
gene
lactic acid
promoter
terminator
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AU2003240481A
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AU2003240481B2 (en
AU2003240481A1 (en
Inventor
Catherine Asleson Dundon
Ben Hause
Stacey Olson
Vineet Rajgarhia
Pirkko Suominen
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NatureWorks LLC
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NatureWorks LLC
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Publication of AU2003240481B2 publication Critical patent/AU2003240481B2/en
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/56—Lactic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters
    • C12P7/625—Polyesters of hydroxy carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/37—Assays involving biological materials from specific organisms or of a specific nature from fungi
    • G01N2333/39—Assays involving biological materials from specific organisms or of a specific nature from fungi from yeasts
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Botany (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU2003240481A 2002-05-30 2003-05-30 Methods and materials for the production of D-lactic acid in yeast Ceased AU2003240481B8 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2008201598A AU2008201598A1 (en) 2002-05-30 2008-04-10 Methods and materials for the production of D-lactic acid in yeast

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38433302P 2002-05-30 2002-05-30
US60/384,333 2002-05-30
PCT/US2003/017310 WO2003102201A2 (en) 2002-05-30 2003-05-30 Methods and materials for the production of d-lactic acid in yeast

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2008201598A Division AU2008201598A1 (en) 2002-05-30 2008-04-10 Methods and materials for the production of D-lactic acid in yeast

Publications (3)

Publication Number Publication Date
AU2003240481A1 AU2003240481A1 (en) 2003-12-19
AU2003240481B2 AU2003240481B2 (en) 2008-01-10
AU2003240481B8 true AU2003240481B8 (en) 2008-03-20

Family

ID=29712012

Family Applications (4)

Application Number Title Priority Date Filing Date
AU2003240481A Ceased AU2003240481B8 (en) 2002-05-30 2003-05-30 Methods and materials for the production of D-lactic acid in yeast
AU2003243366A Ceased AU2003243366B2 (en) 2002-05-30 2003-05-30 Methods and materials for the production of lactic acid in yeast
AU2003251381A Ceased AU2003251381B2 (en) 2002-05-30 2003-05-30 Fermentation process using specific oxygen uptake rates as a process control
AU2008202963A Abandoned AU2008202963A1 (en) 2002-05-30 2008-07-03 Fermentation process using specific oxygen uptake rates as a process control

Family Applications After (3)

Application Number Title Priority Date Filing Date
AU2003243366A Ceased AU2003243366B2 (en) 2002-05-30 2003-05-30 Methods and materials for the production of lactic acid in yeast
AU2003251381A Ceased AU2003251381B2 (en) 2002-05-30 2003-05-30 Fermentation process using specific oxygen uptake rates as a process control
AU2008202963A Abandoned AU2008202963A1 (en) 2002-05-30 2008-07-03 Fermentation process using specific oxygen uptake rates as a process control

Country Status (15)

Country Link
US (7) US20040029256A1 (https=)
EP (4) EP1513923B1 (https=)
JP (4) JP4318638B2 (https=)
CN (4) CN1735683B (https=)
AT (1) ATE367436T1 (https=)
AU (4) AU2003240481B8 (https=)
BR (4) BR0311452A (https=)
CA (3) CA2487296A1 (https=)
DE (1) DE60315028T2 (https=)
DK (1) DK2878675T3 (https=)
ES (3) ES2529254T3 (https=)
PT (1) PT1513923E (https=)
UA (2) UA80976C2 (https=)
WO (3) WO2003102201A2 (https=)
ZA (3) ZA200409529B (https=)

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