ATE448482T1 - Vorrichtungen auf impedanzbasis sowie verfahren zur verwendung in assays - Google Patents

Vorrichtungen auf impedanzbasis sowie verfahren zur verwendung in assays

Info

Publication number
ATE448482T1
ATE448482T1 AT03748948T AT03748948T ATE448482T1 AT E448482 T1 ATE448482 T1 AT E448482T1 AT 03748948 T AT03748948 T AT 03748948T AT 03748948 T AT03748948 T AT 03748948T AT E448482 T1 ATE448482 T1 AT E448482T1
Authority
AT
Austria
Prior art keywords
electrodes
impedance
cells
assay
methods
Prior art date
Application number
AT03748948T
Other languages
English (en)
Inventor
Xiaobo Wang
Xiao Xu
Original Assignee
Acea Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acea Biosciences Inc filed Critical Acea Biosciences Inc
Application granted granted Critical
Publication of ATE448482T1 publication Critical patent/ATE448482T1/de

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/1031Investigating individual particles by measuring electrical or magnetic effects
    • G01N15/12Investigating individual particles by measuring electrical or magnetic effects by observing changes in resistance or impedance across apertures when traversed by individual particles, e.g. by using the Coulter principle
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/48707Physical analysis of biological material of liquid biological material by electrical means
    • G01N33/48728Investigating individual cells, e.g. by patch clamp, voltage clamp
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54373Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438Electrodes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT03748948T 2002-07-20 2003-07-18 Vorrichtungen auf impedanzbasis sowie verfahren zur verwendung in assays ATE448482T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US39774902P 2002-07-20 2002-07-20
US43540002P 2002-12-20 2002-12-20
US46957203P 2003-05-09 2003-05-09
PCT/US2003/022557 WO2004010103A2 (en) 2002-07-20 2003-07-18 Impedance based devices and methods for use in assays

Publications (1)

Publication Number Publication Date
ATE448482T1 true ATE448482T1 (de) 2009-11-15

Family

ID=30773523

Family Applications (2)

Application Number Title Priority Date Filing Date
AT03751801T ATE442587T1 (de) 2002-07-20 2003-07-18 Impedanz basierende vorrichtungen und verfahren zur analyse von zellen und partikeln
AT03748948T ATE448482T1 (de) 2002-07-20 2003-07-18 Vorrichtungen auf impedanzbasis sowie verfahren zur verwendung in assays

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT03751801T ATE442587T1 (de) 2002-07-20 2003-07-18 Impedanz basierende vorrichtungen und verfahren zur analyse von zellen und partikeln

Country Status (10)

Country Link
US (1) US7459303B2 (de)
EP (2) EP1539992B1 (de)
JP (2) JP4745056B2 (de)
CN (2) CN100577811C (de)
AT (2) ATE442587T1 (de)
AU (2) AU2003269911A1 (de)
CA (2) CA2493101C (de)
DE (2) DE60329187D1 (de)
HK (2) HK1082002A1 (de)
WO (2) WO2004010102A2 (de)

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