ATE366314T1 - Infektioese rna virus-klone, vakzine und davon abgeleitete diagnostische assays - Google Patents
Infektioese rna virus-klone, vakzine und davon abgeleitete diagnostische assaysInfo
- Publication number
- ATE366314T1 ATE366314T1 AT97954491T AT97954491T ATE366314T1 AT E366314 T1 ATE366314 T1 AT E366314T1 AT 97954491 T AT97954491 T AT 97954491T AT 97954491 T AT97954491 T AT 97954491T AT E366314 T1 ATE366314 T1 AT E366314T1
- Authority
- AT
- Austria
- Prior art keywords
- vaccines
- rna virus
- diagnostic assay
- genome
- infectious rna
- Prior art date
Links
- 208000015181 infectious disease Diseases 0.000 title abstract 5
- 230000002458 infectious effect Effects 0.000 title abstract 4
- 241000700605 Viruses Species 0.000 title abstract 2
- 238000003556 assay Methods 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 241001493065 dsRNA viruses Species 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP96203024A EP0839912A1 (de) | 1996-10-30 | 1996-10-30 | Ansteckende Klone von RNA-Viren und darauf basierende Impfstoffe und diagnostisches Verfahren |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE366314T1 true ATE366314T1 (de) | 2007-07-15 |
Family
ID=8224533
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97954491T ATE366314T1 (de) | 1996-10-30 | 1997-10-29 | Infektioese rna virus-klone, vakzine und davon abgeleitete diagnostische assays |
Country Status (23)
| Country | Link |
|---|---|
| US (5) | US6268199B1 (de) |
| EP (2) | EP0839912A1 (de) |
| JP (1) | JP3921552B2 (de) |
| KR (1) | KR100437254B1 (de) |
| CN (1) | CN1138859C (de) |
| AT (1) | ATE366314T1 (de) |
| AU (1) | AU719991B2 (de) |
| BR (1) | BR9712592A (de) |
| CA (1) | CA2272046C (de) |
| CZ (1) | CZ294781B6 (de) |
| DE (1) | DE69737886T2 (de) |
| DK (1) | DK0935660T3 (de) |
| ES (1) | ES2290973T3 (de) |
| HU (1) | HUP9903829A3 (de) |
| ID (1) | ID22208A (de) |
| MY (1) | MY117686A (de) |
| PL (1) | PL191258B1 (de) |
| PT (1) | PT935660E (de) |
| SI (1) | SI0935660T1 (de) |
| SK (1) | SK286231B6 (de) |
| UA (1) | UA72433C2 (de) |
| WO (1) | WO1998018933A1 (de) |
| ZA (1) | ZA979732B (de) |
Families Citing this family (79)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040224327A1 (en) * | 1996-10-30 | 2004-11-11 | Meulenberg Johanna Jacoba Maria | Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof |
| EP0839912A1 (de) * | 1996-10-30 | 1998-05-06 | Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) | Ansteckende Klone von RNA-Viren und darauf basierende Impfstoffe und diagnostisches Verfahren |
| EP0974660A1 (de) * | 1998-06-19 | 2000-01-26 | Stichting Instituut voor Dierhouderij en Diergezondheid (ID-DLO) | Newcastle-Krankheitsvirus Infektiöser Klone, Impfstoffe und Diagnosetest |
| US7691389B2 (en) * | 1998-12-22 | 2010-04-06 | Pfizer Inc | Infectious cDNA clone of north american porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof |
| US7618797B2 (en) | 1998-12-22 | 2009-11-17 | Pfizer Inc | Infectious cDNA clone of North American porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof |
| NZ501264A (en) | 1998-12-22 | 2001-09-28 | Pfizer Prod Inc | Polynucleotide DNA sequence encoding an infectious RNA molecule encoding a North American PRRS |
| US7132106B2 (en) * | 1998-12-22 | 2006-11-07 | Pfizer Inc. | Infectious cDNA clone of North American porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof |
| PL204373B1 (pl) | 1999-03-08 | 2010-01-29 | Boehringer Ingelheim Vetemendi | Replikony zespołu reprodukcyjnego i oddechowego świń (PRRSV), zastosowanie replikonów PRRSV, szczepionki zawierające replikony PRRSV i zastosowanie tych szczepionek |
| WO2000065032A1 (en) | 1999-04-22 | 2000-11-02 | United States Department Of Agriculture | Porcine reproductive and respiratory syndrome vaccine, based on isolate ja-142 |
| HUP0204176A3 (en) * | 2000-01-26 | 2003-12-29 | Boehringer Ingelheim Vetmed | Recombinant attenuation of prrsv |
| EP1156111A1 (de) | 2000-05-19 | 2001-11-21 | Stichting Dienst Landbouwkundig Onderzoek | Chimäre Arterivirus-ähnliche Partikel |
| ES2240745T3 (es) | 2001-06-05 | 2005-10-16 | Curevac Gmbh | Composicion farmaceutica que contiene un arnm estabilizado y optimizado para la traduccion, adecuada como vacuna y como regenerante de tejidos. |
| DE10162480A1 (de) | 2001-12-19 | 2003-08-07 | Ingmar Hoerr | Die Applikation von mRNA für den Einsatz als Therapeutikum gegen Tumorerkrankungen |
| US6841364B2 (en) | 2002-01-22 | 2005-01-11 | Protatek International, Inc. | Infectious cDNA clones of porcine reproductive and respiratory syndrome virus and expression vectors thereof |
| DE10229872A1 (de) * | 2002-07-03 | 2004-01-29 | Curevac Gmbh | Immunstimulation durch chemisch modifizierte RNA |
| DE10347710B4 (de) | 2003-10-14 | 2006-03-30 | Johannes-Gutenberg-Universität Mainz | Rekombinante Impfstoffe und deren Verwendung |
| AR049924A1 (es) | 2004-06-18 | 2006-09-13 | Univ Minnesota | Identificacion de organismos viralmente infectados y vacunados |
| KR100872840B1 (ko) | 2004-07-09 | 2008-12-22 | (주)씨아이디 | 돼지생식기호흡기증후군 바이러스에 대한 전체-길이의감염성이 있는 cDNA 클론 및 이의 용도 |
| US20060020227A1 (en) * | 2004-07-20 | 2006-01-26 | Moore Thomas E | Collection means and a method for collecting cord blood |
| US7632636B2 (en) | 2004-09-21 | 2009-12-15 | Boehringer Ingelheim Vetmedica, Inc. | Porcine reproductive and respiratory syndrome isolates and methods of use |
| CN101189027A (zh) | 2005-01-13 | 2008-05-28 | 贝林格尔·英格海姆维特梅迪卡有限公司 | 改良的prrs疫苗 |
| BRPI0606189A2 (pt) * | 2005-02-25 | 2009-06-09 | Pfizer Prod Inc | composição, vacina e método para proteger um animal porcino de infecção por um vìrus de prrs, célula hospedeira transfectada, método para fazer um vìrus de prrs geneticamente modificado e atenuado |
| HUE031018T2 (hu) | 2005-06-24 | 2017-06-28 | Univ Minnesota | PRRS vírusok, fertõzõ klónok, ezek mutánsai és alkalmazási eljárások |
| JP2009506129A (ja) * | 2005-08-30 | 2009-02-12 | ボード・オブ・リージエンツ・オブ・ザ・ユニバーシテイ・オブ・ネブラスカ | 改善された免疫原性を有するｐｒｒｓｖ抗原で動物を予防接種するための方法及び組成物 |
| DE102005046490A1 (de) | 2005-09-28 | 2007-03-29 | Johannes-Gutenberg-Universität Mainz | Modifikationen von RNA, die zu einer erhöhten Transkriptstabilität und Translationseffizienz führen |
| JP2010507361A (ja) | 2006-07-31 | 2010-03-11 | キュアバック ゲーエムベーハー | 具体的には免疫刺激剤／アジュバントとしての、一般式（Ｉ）：ＧｌＸｍＧｎ、または一般式（ＩＩ）：ＣｌＸｍＣｎで表される核酸 |
| US7666585B2 (en) | 2007-06-15 | 2010-02-23 | Protatek International, Inc. | Construction of chimera PRRSV, compositions and vaccine preparations |
| WO2008153572A1 (en) * | 2007-06-15 | 2008-12-18 | Protatek International, Inc. | Construction of chimera prrsv, compositions and vaccine preparations |
| EP2181189B1 (de) * | 2007-06-25 | 2012-06-20 | South Dakota State University | Rekombinantes nordamerikanisches prrs-virus typ 1 und seine verwendung |
| WO2009030254A1 (en) | 2007-09-04 | 2009-03-12 | Curevac Gmbh | Complexes of rna and cationic peptides for transfection and for immunostimulation |
| EP2548960B1 (de) | 2008-01-31 | 2018-01-31 | CureVac AG | Nukleinsäure der Formel (NuGIXmGnNv)a und Derivate davon als immunstimulierendes Mittel/Adjuvans |
| RU2561595C2 (ru) * | 2008-08-25 | 2015-08-27 | Бёрингер Ингельхайм Ветмедика, Инк. | Вакцина против высокопатогенного репродуктивно-респираторного синдрома свиней (hp prrs) |
| WO2010037408A1 (en) | 2008-09-30 | 2010-04-08 | Curevac Gmbh | Composition comprising a complexed (m)rna and a naked mrna for providing or enhancing an immunostimulatory response in a mammal and uses thereof |
| AR078253A1 (es) | 2009-09-02 | 2011-10-26 | Boehringer Ingelheim Vetmed | Metodos para reducir la actividad antivirica en composiciones pcv-2 y composiciones pcv-2 con mejor inmunogenicidad |
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| ES2558106T3 (es) | 2010-07-30 | 2016-02-02 | Curevac Ag | Formación de complejos de ácidos nucleicos con componentes catiónicos disulfuro-reticulados para la transfección e inmunoestimulación |
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| UA108902C2 (uk) | 2010-11-10 | 2015-06-25 | Вірус північноамериканського репродуктивного та респіраторного синдрому свиней (prrs) та його застосування | |
| UA117272C2 (uk) | 2011-02-17 | 2018-07-10 | Бьорінгер Інгельхайм Ветмедіка Гмбх | Новий європейський штам prrsv |
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| WO2013113326A1 (en) | 2012-01-31 | 2013-08-08 | Curevac Gmbh | Pharmaceutical composition comprising a polymeric carrier cargo complex and at least one protein or peptide antigen |
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| CA2936286A1 (en) | 2014-04-01 | 2015-10-08 | Curevac Ag | Polymeric carrier cargo complex for use as an immunostimulating agent or as an adjuvant |
| JP6398454B2 (ja) * | 2014-08-13 | 2018-10-03 | セイコーエプソン株式会社 | 圧電駆動装置、ロボット、及び、それらの駆動方法 |
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| JP6986078B2 (ja) | 2016-08-05 | 2021-12-22 | ヒプラ サイエンティフィック，エス．エル．ユー． | ブタ生殖器呼吸器症候群ウイルスｃＤＮＡクローンおよびその用途 |
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1996
- 1996-10-30 EP EP96203024A patent/EP0839912A1/de not_active Withdrawn
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1997
- 1997-10-29 ID IDW990271A patent/ID22208A/id unknown
- 1997-10-29 CN CNB97180706XA patent/CN1138859C/zh not_active Expired - Lifetime
- 1997-10-29 BR BR9712592-0A patent/BR9712592A/pt not_active Application Discontinuation
- 1997-10-29 SI SI9730768T patent/SI0935660T1/sl unknown
- 1997-10-29 CZ CZ19991564A patent/CZ294781B6/cs not_active IP Right Cessation
- 1997-10-29 US US09/297,535 patent/US6268199B1/en not_active Expired - Lifetime
- 1997-10-29 DE DE69737886T patent/DE69737886T2/de not_active Expired - Lifetime
- 1997-10-29 PL PL333070A patent/PL191258B1/pl not_active IP Right Cessation
- 1997-10-29 AT AT97954491T patent/ATE366314T1/de active
- 1997-10-29 MY MYPI97005141A patent/MY117686A/en unknown
- 1997-10-29 CA CA2272046A patent/CA2272046C/en not_active Expired - Lifetime
- 1997-10-29 UA UA99052951A patent/UA72433C2/uk unknown
- 1997-10-29 ZA ZA9709732A patent/ZA979732B/xx unknown
- 1997-10-29 JP JP52032198A patent/JP3921552B2/ja not_active Expired - Lifetime
- 1997-10-29 HU HU9903829A patent/HUP9903829A3/hu unknown
- 1997-10-29 AU AU58828/98A patent/AU719991B2/en not_active Expired
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- 1997-10-29 DK DK97954491T patent/DK0935660T3/da active
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- 1997-10-29 KR KR10-1999-7003788A patent/KR100437254B1/ko not_active IP Right Cessation
- 1997-10-29 EP EP97954491A patent/EP0935660B1/de not_active Expired - Lifetime
- 1997-10-29 SK SK547-99A patent/SK286231B6/sk not_active IP Right Cessation
- 1997-10-29 WO PCT/NL1997/000593 patent/WO1998018933A1/en active IP Right Grant
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2001
- 2001-06-05 US US09/874,626 patent/US20020098573A1/en not_active Abandoned
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2003
- 2003-12-30 US US10/750,410 patent/US20040197872A1/en not_active Abandoned
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2005
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