PT82505B - Processo de preparacao de celulas hibridas produtoras de um antigenie caracteristico do virus da hepatite b obtido a partir de hepatocitos e de celulas estabilizadas de simio - Google Patents
Processo de preparacao de celulas hibridas produtoras de um antigenie caracteristico do virus da hepatite b obtido a partir de hepatocitos e de celulas estabilizadas de simioInfo
- Publication number
- PT82505B PT82505B PT82505A PT8250586A PT82505B PT 82505 B PT82505 B PT 82505B PT 82505 A PT82505 A PT 82505A PT 8250586 A PT8250586 A PT 8250586A PT 82505 B PT82505 B PT 82505B
- Authority
- PT
- Portugal
- Prior art keywords
- cells
- hepatitis
- hepatocytes
- simelo
- virus obtained
- Prior art date
Links
- 241000700721 Hepatitis B virus Species 0.000 title abstract 2
- 210000004027 cell Anatomy 0.000 title abstract 2
- 210000003494 hepatocyte Anatomy 0.000 title abstract 2
- 210000004754 hybrid cell Anatomy 0.000 title abstract 2
- 239000000427 antigen Substances 0.000 title 1
- 102000036639 antigens Human genes 0.000 title 1
- 108091007433 antigens Proteins 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 241000282693 Cercopithecidae Species 0.000 abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- 238000003501 co-culture Methods 0.000 abstract 2
- 108020004414 DNA Proteins 0.000 abstract 1
- 241000282577 Pan troglodytes Species 0.000 abstract 1
- 230000001413 cellular effect Effects 0.000 abstract 1
- 210000003527 eukaryotic cell Anatomy 0.000 abstract 1
- 238000009396 hybridization Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C12N5/12—Fused cells, e.g. hybridomas
- C12N5/16—Animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Silicates, Zeolites, And Molecular Sieves (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR858506706A FR2581393B2 (fr) | 1985-05-02 | 1985-05-02 | Cellules hybrides productrices d'un antigene caracteristique du virus de l'hepatite b obtenu a partir d'hepatocytes et de cellules etablies de singe, procede pour l'obtention de ces cellules hybrides et application de celles-ci a la production de l'antigene susdit |
Publications (2)
Publication Number | Publication Date |
---|---|
PT82505A PT82505A (fr) | 1986-06-01 |
PT82505B true PT82505B (pt) | 1989-12-29 |
Family
ID=9318906
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT82505A PT82505B (pt) | 1985-05-02 | 1986-05-02 | Processo de preparacao de celulas hibridas produtoras de um antigenie caracteristico do virus da hepatite b obtido a partir de hepatocitos e de celulas estabilizadas de simio |
Country Status (12)
Country | Link |
---|---|
US (1) | US5112748A (pt) |
EP (1) | EP0200653B1 (pt) |
JP (1) | JPS6229971A (pt) |
AT (1) | ATE51026T1 (pt) |
CA (1) | CA1277934C (pt) |
DE (1) | DE3669529D1 (pt) |
DK (1) | DK204586A (pt) |
ES (1) | ES8703519A1 (pt) |
FR (1) | FR2581393B2 (pt) |
GR (1) | GR861142B (pt) |
PT (1) | PT82505B (pt) |
WO (1) | WO1993013203A1 (pt) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7766329B1 (en) | 1992-10-02 | 2010-08-03 | Sierra Design Group | Wheel indicator and ticket dispenser apparatus |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2757169A1 (de) * | 1977-12-22 | 1979-07-05 | Hoechst Ag | Verfahren zur gewinnung insulin produzierender tierischer zellen |
FR2458584A1 (fr) * | 1979-06-08 | 1981-01-02 | Pasteur Institut | Vecteurs pour le transfert et l'expression de materiel genetique dans une cellule eucaryote et procede pour la production d'une proteine determinee dans des cellules eucaryotes |
FR2480780B1 (fr) * | 1980-04-22 | 1985-12-06 | Pasteur Institut | Procede de transformation de cellules, notamment eucaryotes, par un adn circulaire tel que celui du virus de l'hepatite b et preparations contenant les produits d'expression desdits adn |
JPS6045848B2 (ja) * | 1980-07-31 | 1985-10-12 | 株式会社林原生物化学研究所 | ヒト成長ホルモンの製造方法 |
FR2500847B1 (fr) * | 1981-03-02 | 1985-09-13 | Pasteur Institut | Marqueurs genetiques selectifs pour cellules eucaryotes, procede de mise en oeuvre de tels marqueurs et application des cellules contenant un tel marqueur a la fabrication de proteines determinees apres leur transformation par un adn correspondant |
EP0062574A3 (en) * | 1981-03-31 | 1982-12-29 | The Regents Of The University Of California | Virus protein synthesis |
DE3245665A1 (de) * | 1982-05-04 | 1983-11-10 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren zur herstellung permanenter tierischer und humaner zellinien und deren verwendung |
JPS58201988A (ja) * | 1982-05-04 | 1983-11-25 | ベ−リンガ−・マンハイム・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング | 永久培養可能な動物及びヒトの細胞系を得る方法 |
US4608339A (en) * | 1983-10-25 | 1986-08-26 | Yoakum George H | Protoplast fusion method for high-frequency DNA transfection in human cells |
FR2555607B2 (fr) * | 1983-11-30 | 1986-10-03 | Pasteur Institut | Culture de cellules eucaryotes productrices d'une proteine vaccinante, notamment d'antigene hbs |
FR2565995B1 (fr) * | 1984-03-07 | 1987-10-23 | Centre Nat Rech Scient | Cellules hybrides productrices d'un polypeptide determine et obtenu a partir de cellules primaires naturellement capables d'exprimer ce polypeptide ou un polypeptide equivalent, procede pour l'obtention de ces cellules hybrides et application de celles-ci a la production dudit polypeptide |
-
1985
- 1985-05-02 FR FR858506706A patent/FR2581393B2/fr not_active Expired
-
1986
- 1986-04-29 DE DE8686400945T patent/DE3669529D1/de not_active Expired - Lifetime
- 1986-04-29 US US07/031,465 patent/US5112748A/en not_active Expired - Fee Related
- 1986-04-29 WO PCT/FR1986/000147 patent/WO1993013203A1/fr unknown
- 1986-04-29 AT AT86400945T patent/ATE51026T1/de not_active IP Right Cessation
- 1986-04-29 EP EP86400945A patent/EP0200653B1/fr not_active Expired - Lifetime
- 1986-04-29 GR GR861142A patent/GR861142B/el unknown
- 1986-05-02 PT PT82505A patent/PT82505B/pt not_active IP Right Cessation
- 1986-05-02 CA CA000508230A patent/CA1277934C/fr not_active Expired - Fee Related
- 1986-05-02 JP JP61102930A patent/JPS6229971A/ja active Pending
- 1986-05-02 ES ES555123A patent/ES8703519A1/es not_active Expired
- 1986-05-02 DK DK204586A patent/DK204586A/da not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
ES555123A0 (es) | 1987-03-01 |
GR861142B (en) | 1986-08-11 |
PT82505A (fr) | 1986-06-01 |
FR2581393A2 (fr) | 1986-11-07 |
US5112748A (en) | 1992-05-12 |
JPS6229971A (ja) | 1987-02-07 |
EP0200653B1 (fr) | 1990-03-14 |
EP0200653A1 (fr) | 1986-11-05 |
ES8703519A1 (es) | 1987-03-01 |
FR2581393B2 (fr) | 1989-07-21 |
CA1277934C (fr) | 1990-12-18 |
DK204586D0 (da) | 1986-05-02 |
DK204586A (da) | 1986-11-03 |
DE3669529D1 (de) | 1990-04-19 |
ATE51026T1 (de) | 1990-03-15 |
WO1993013203A1 (fr) | 1993-07-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MY117686A (en) | Infectious clones of rna viruses and vaccines and diagnostic assays derived thereof | |
DK15182A (da) | Fremgangsmaade til fremstilling af recombinant-dna | |
DK577783A (da) | Vektor for udtrykkelse af et dna-segment i gaer | |
DE69638196D1 (de) | Rekombinantes sendai-virus | |
ES8105388A1 (es) | Un metodo para mantener, replicar y expresar por lo menos una porcion del genoma de un virus n.p. | |
DE69233639D1 (de) | Polynukleotidabschnitt des HPV16-Genoms | |
NO874750D0 (no) | Bestemte dna-sekvenser avledet fra en papillomavirusgenom, deres bruk i in vitro diagnostikk og produksjon av antigene preparater. | |
WO1993000365A3 (en) | Hepatitis c virus (hcv) polypeptides | |
DE69031791D1 (de) | Verfahren zur HCV-Züchtung in Zell-Linien aus B- oder T-Lymphozyten | |
DK149589D0 (da) | Dna-sekvens, dna-vektor, muteret hiv-virusgenom, hiv-vaccine og fremgangsmaade til fremstilling af samme | |
AU7234987A (en) | Viral vector coding for a glycoprotein of the virus responsible for a.i.d.s., vaccine and antibody | |
DE3585578D1 (de) | Hepatitisoberflaechenantigenpartikelvakzin. | |
EP0105141A3 (en) | Recombinant dna molecules, process for their production, their use for production of hepatitis b surface antigen (hbsag) and pharmaceutical compositions containing this hbsag | |
PT82505B (pt) | Processo de preparacao de celulas hibridas produtoras de um antigenie caracteristico do virus da hepatite b obtido a partir de hepatocitos e de celulas estabilizadas de simio | |
DK326289D0 (da) | Fremgangsmaade til fremstilling af et protein ud fra gaersvampe under anvendelse af et inducerbart system, samt vektorer og transformerede stammer til brug ved fremgangsmaaden | |
ATE179428T1 (de) | Verfahren zur herstellung von hepatitis antigenen und impfstoffen | |
DK498387A (da) | Virus-dna-sekvens | |
GR3015892T3 (en) | Virus resistant plants having a viral coat protein. | |
ATE31733T1 (de) | Verfahren zur herstellung von hybridisierungssonden. | |
KR880007728A (ko) | 비루스 벡터 및 재조합 dna | |
ATE389726T1 (de) | Infektiöse vektoren und pflanzenklone, die sich von turnip mosaikvirus herleiten | |
KR880004092A (ko) | 두창비루스의 a-형 봉입체용 유전자 | |
KR960023060A (ko) | 에리스로포이에틴의 제조방법 | |
DK107493A (da) | Vektor for udtrykkelse i gaer, bestaaende af et fremmed dna-segment og en fremgangsmaade til syntese af fremmede proteiner ved hjaelp af en saadan vektor |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19941231 |