DE69638196D1 - Rekombinantes sendai-virus - Google Patents
Rekombinantes sendai-virusInfo
- Publication number
- DE69638196D1 DE69638196D1 DE69638196T DE69638196T DE69638196D1 DE 69638196 D1 DE69638196 D1 DE 69638196D1 DE 69638196 T DE69638196 T DE 69638196T DE 69638196 T DE69638196 T DE 69638196T DE 69638196 D1 DE69638196 D1 DE 69638196D1
- Authority
- DE
- Germany
- Prior art keywords
- sendai virus
- recombinant sendai
- virus
- transfecting
- regenerating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18811—Sendai virus
- C12N2760/18841—Use of virus, viral particle or viral elements as a vector
- C12N2760/18843—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18811—Sendai virus
- C12N2760/18851—Methods of production or purification of viral material
- C12N2760/18852—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP28541795 | 1995-11-01 | ||
PCT/JP1996/003069 WO1997016539A1 (fr) | 1995-11-01 | 1996-10-22 | Virus sendai recombinant |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69638196D1 true DE69638196D1 (de) | 2010-07-22 |
Family
ID=17691258
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69638196T Expired - Lifetime DE69638196D1 (de) | 1995-11-01 | 1996-10-22 | Rekombinantes sendai-virus |
Country Status (11)
Country | Link |
---|---|
US (2) | US7101685B2 (de) |
EP (1) | EP0863202B1 (de) |
KR (1) | KR100525687B1 (de) |
CN (1) | CN1143892C (de) |
AT (1) | ATE470704T1 (de) |
AU (1) | AU7335296A (de) |
CA (1) | CA2236378C (de) |
DE (1) | DE69638196D1 (de) |
DK (1) | DK0863202T3 (de) |
HK (1) | HK1018078A1 (de) |
WO (1) | WO1997016539A1 (de) |
Families Citing this family (80)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100525687B1 (ko) * | 1995-11-01 | 2005-11-25 | 가부시끼가이샤 디나벡 겡뀨쇼 | 재조합체 센다이바이러스 |
CN1129530C (zh) * | 1998-05-18 | 2003-12-03 | 精工爱普生株式会社 | 喷墨打印设备 |
US7241617B2 (en) | 1998-07-03 | 2007-07-10 | Dnavec Research, Inc. | Sendai viral vectors comprising foreign genes inserted between the R1 and R2 Loci |
ATE430806T1 (de) * | 1998-07-03 | 2009-05-15 | Dnavec Research Inc | (-)-strang rns virusvektor für nervenzellen |
US6828138B1 (en) * | 1998-08-11 | 2004-12-07 | Dnavec Research Inc. | Recombinant sendai virus vector including a gene encoding a chemokine |
US6544785B1 (en) | 1998-09-14 | 2003-04-08 | Mount Sinai School Of Medicine Of New York University | Helper-free rescue of recombinant negative strand RNA viruses |
DE69933528T2 (de) * | 1998-11-09 | 2007-08-09 | Nippon Biologicals, Inc. | Verfahren zur Cytokinproduktionn unter Verwendung eines Sendai Virus Expressionssystems |
US6490775B1 (en) * | 1999-04-23 | 2002-12-10 | Veri-Tek Inc. | Press operation verification system |
US7226786B2 (en) | 1999-05-18 | 2007-06-05 | Dnavec Research Inc. | Envelope gene-deficient Paramyxovirus vector |
DE60035589T2 (de) * | 1999-05-18 | 2008-04-17 | Dnavec Research Inc., Tsukuba | Viraler paramyxoviridae vektor mit einem defekten hüllprotein-gen |
US20030166252A1 (en) * | 1999-05-18 | 2003-09-04 | Kaio Kitazato | Paramyxovirus-derived RNP |
EP1211318B1 (de) | 1999-09-06 | 2007-08-08 | DNAVEC Research, Inc. | Paramyxoviren, die eine modifizierte transkriptionsstartsequenz umfassen |
KR100772276B1 (ko) | 1999-11-02 | 2007-11-01 | 가부시키가이샤 디나벡크 겐큐쇼 | 기도 상피로의 외인성 유전자 도입용 재조합센다이바이러스 벡터 |
JP4838962B2 (ja) * | 1999-11-02 | 2011-12-14 | 株式会社ディナベック研究所 | 気道上皮細胞への外因性遺伝子導入用組換えセンダイウイルスベクター |
US7314614B1 (en) | 1999-11-02 | 2008-01-01 | Dnavec Research, Inc. | Recombinant sendai virus vector for introducing exogenous genes to airway epithelia |
CA2397903A1 (en) * | 2000-01-19 | 2001-07-26 | Dnavec Research Inc. | Use of paramyxovirus vector for gene transfer into blood vessel |
EP1270016A4 (de) | 2000-03-30 | 2005-10-19 | Dnavec Research Inc | Aidsvirus-impfstoff unter verwendung eines sendaivirus-vektors |
JP2001275684A (ja) * | 2000-03-31 | 2001-10-09 | Nippon Medical Research Kk | 組換え体イヌジステンパーウイルスおよびその作製方法 |
CA2322057A1 (en) | 2000-05-18 | 2001-11-18 | Dnavec Research Inc. | Paramyxovirus vectors used for transfer of foreign genes |
AU2001264824A1 (en) * | 2000-06-01 | 2001-12-11 | St. Jude Children's Research Hospital | Vaccine and gene therapy vector and methods of use thereof |
CN100531802C (zh) * | 2000-06-01 | 2009-08-26 | 株式会社载体研究所 | 含有血凝素活性膜蛋白质的假型逆转录病毒载体 |
WO2002000264A1 (fr) * | 2000-06-27 | 2002-01-03 | Dnavec Research Inc. | Vecteur de virus pour transfert de gene dans des cellules renales |
CN1526014A (zh) * | 2000-10-06 | 2004-09-01 | ��ʽ���������о��� | 用于将外源基因导入骨骼肌的副粘病毒载体 |
JP2002142770A (ja) * | 2000-11-08 | 2002-05-21 | Dnavec Research Inc | 循環系への遺伝子送達用パラミクソウイルスベクター |
AU2002224113A1 (en) | 2000-11-27 | 2002-06-03 | Dnavec Research Inc. | Paramyxovirus vector encoding angiogenesis gene and utilization thereof |
US6596206B2 (en) * | 2001-03-30 | 2003-07-22 | Picoliter Inc. | Generation of pharmaceutical agent particles using focused acoustic energy |
US7465456B2 (en) | 2002-04-26 | 2008-12-16 | Medimmune, Llc | Multi plasmid system for the production of influenza virus |
AU2003231083A1 (en) | 2002-04-26 | 2003-11-10 | Medimmune, Llc | Multi plasmid system for the production of influenza virus |
WO2003092738A1 (fr) * | 2002-04-30 | 2003-11-13 | Dnavec Research Inc. | Composition support de medicament ou de gene avec activite d'hemagglutinine |
WO2003102183A1 (fr) * | 2002-06-03 | 2003-12-11 | Dnavec Research Inc. | Vecteurs de paramyxovirus codant pour un anticorps et son utilisation |
AU2003261931A1 (en) * | 2002-09-04 | 2004-03-29 | Dnavec Research Inc. | Process for producing virus vector containing membrane protein having sialic acid-binding activitiy in envelope with the use of gram-positive bacterium-origin neuraminidase |
JPWO2004038029A1 (ja) * | 2002-10-24 | 2006-02-23 | 株式会社ディナベック研究所 | T細胞に遺伝子を導入する方法 |
WO2005018539A2 (en) | 2003-06-16 | 2005-03-03 | Medimmune Vaccines, Inc. | Influenza hemagglutinin and neuraminidase variants |
JPWO2005001082A1 (ja) * | 2003-06-30 | 2006-08-10 | 株式会社ディナベック研究所 | 高変異領域が改変された遺伝子を搭載するマイナス鎖rnaウイルスベクター |
CA2544786A1 (en) * | 2003-11-04 | 2005-05-12 | Dnavec Research Inc. | Method for producing gene transferred dendritic cells |
DE602004027537D1 (de) | 2003-12-23 | 2010-07-15 | Medimmune Inc | |
CN1929867A (zh) | 2004-01-13 | 2007-03-14 | 株式会社载体研究所 | 肿瘤的基因治疗,即利用编码免疫刺激性细胞因子的单链负链rna病毒载体进行的治疗 |
CN1934260B (zh) | 2004-01-22 | 2013-03-13 | 株式会社载体研究所 | 利用含有巨细胞病毒增强子和鸡β-肌动蛋白启动子的杂合启动子制造负链RNA病毒载体的方法 |
WO2005071085A1 (ja) * | 2004-01-22 | 2005-08-04 | Dnavec Research Inc. | ウイルスベクターの製造方法 |
JPWO2005087269A1 (ja) * | 2004-03-16 | 2008-01-24 | 株式会社ディナベック研究所 | 腫瘍増殖を抑制する方法 |
US20080038234A1 (en) * | 2004-03-23 | 2008-02-14 | Shuji Hayashi | Bone Marrow-Related Cells Associated With Tissue Maintenance And/Or Repair |
CA2822895A1 (en) | 2004-05-25 | 2005-12-08 | Medimmune, Llc | Influenza hemagglutinin and neuraminidase variants |
CN101006172B (zh) | 2004-06-24 | 2012-09-05 | 株式会社载体研究所 | 包含导入了rna病毒的树突状细胞的抗癌剂 |
DE102005006388A1 (de) * | 2005-02-11 | 2006-08-24 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Replikationsdefiziente RNA-Viren als Impfstoffe |
ES2527503T3 (es) | 2005-03-08 | 2015-01-26 | Medimmune, Llc | Virus influenza reordenantes |
WO2006134917A1 (ja) | 2005-06-14 | 2006-12-21 | Dnavec Corporation | 抗体の作製方法 |
EP2993235B1 (de) | 2005-10-28 | 2019-02-13 | ID Pharma Co., Ltd. | Gentransfer in epithelialen stammzellen der atemwege unter verwendung von similian lentiviralen vektoren mit senadai rna-virus-spikeprotein pseudotypisierten vektoren |
US20100167341A1 (en) * | 2006-01-17 | 2010-07-01 | Dnavec Corporation | Novel protein expression system |
JPWO2007139178A1 (ja) | 2006-05-31 | 2009-10-15 | ディナベック株式会社 | アルツハイマー病治療薬 |
EP2048232A4 (de) * | 2006-07-13 | 2010-10-13 | Dnavec Corp | Nichtreplizierender paramyxoviridae-virusvektor |
WO2008133701A1 (en) | 2006-07-21 | 2008-11-06 | Medimmune, Llc. | Methods and compositions for increasing replication capacity of an influenza virus |
CN104278014A (zh) | 2006-08-09 | 2015-01-14 | 米迪缪尼有限公司 | 流感血凝素和神经氨酸酶变体 |
US20110021600A1 (en) | 2006-09-04 | 2011-01-27 | Kyowa Hakko Kirin Co., Ltd. | Novel nucleic acid |
WO2008100292A2 (en) | 2006-10-16 | 2008-08-21 | Genelux Corporation | Modified vaccinia virus strains for use in diagnostic and therapeutic methods |
JPWO2008084319A1 (ja) | 2006-12-18 | 2010-04-30 | 協和発酵キリン株式会社 | 新規核酸 |
US20100323428A1 (en) | 2007-02-07 | 2010-12-23 | Dnavec Corporation | Attenuated minus-stranded rna virus |
US9145564B2 (en) * | 2007-04-13 | 2015-09-29 | National Institute Of Advanced Industrial Science And Technology | Persistently infective Sendai virus vector |
EP2143794A1 (de) | 2007-04-27 | 2010-01-13 | Kyushu University, National University Corporation | Viraler vektor für gentherapie |
EP2674486A1 (de) | 2007-06-18 | 2013-12-18 | MedImmune, LLC | Influenza-B-Viren mit Veränderungen im Hämagglutininpolypeptid |
WO2009044899A1 (ja) | 2007-10-03 | 2009-04-09 | Kyowa Hakko Kirin Co., Ltd. | 細胞の増殖を制御する核酸 |
WO2009148137A1 (ja) | 2008-06-04 | 2009-12-10 | 協和発酵キリン株式会社 | 肥満細胞の脱顆粒を制御する核酸 |
CA2730408A1 (en) | 2008-07-11 | 2010-01-14 | Chin-Fen Yang | Influenza hemagglutinin and neuraminidase variants |
EP3075850B1 (de) | 2008-07-16 | 2019-02-06 | ID Pharma Co., Ltd. | Verfahren zur herstellung einer neuprogrammierten zelle anhand eines chromosomal unintegrierten virusvektors |
CN102272302B (zh) | 2008-10-31 | 2015-04-15 | 生物载体株式会社 | 增强重组蛋白表达的方法 |
EP2396033B1 (de) | 2009-02-12 | 2016-09-28 | MedImmune, LLC | Influenza-hämagglutinin- und neuraminidase-varianten |
JP2009268471A (ja) * | 2009-08-07 | 2009-11-19 | Dnavec Research Inc | センダイウイルスベクターを用いたワクチンおよびワクチンタンパク質 |
CN102711812B (zh) | 2010-01-08 | 2014-07-16 | 国立大学法人京都大学 | Tau蛋白病治疗用疫苗 |
EP2612911B1 (de) | 2010-08-30 | 2018-01-17 | ID Pharma Co., Ltd. | Zusammensetzung zur induktion pluripotenter stammzellen und ihre verwendung |
CN102205118B (zh) * | 2011-03-25 | 2013-05-22 | 天津济命生生物科技有限公司 | 一种生物制品及其制备方法 |
US9637758B2 (en) | 2011-04-28 | 2017-05-02 | St. Jude Children's Research Hospital | Modified Sendai virus vaccine and imaging vector |
US9951349B2 (en) * | 2011-09-27 | 2018-04-24 | Yale University | Compositions and methods for transient expression of recombinant RNA |
RU2519763C9 (ru) * | 2012-11-26 | 2015-04-27 | Ольга Вячеславовна Матвеева | Метод иммунотерапии онкологических заболеваний и фармацевтические композиции на основе онколитического вируса сендай |
US10975358B2 (en) | 2013-09-24 | 2021-04-13 | Id Pharma Co., Ltd. | Method for improving efficiency of inducing pluripotent stem cell |
JP7150241B2 (ja) | 2016-11-17 | 2022-10-11 | 国立感染症研究所長 | 非感染性パラミクソウイルス粒子を用いた感染症ワクチン |
CA3070552A1 (en) | 2017-07-21 | 2019-01-24 | I'rom Group Co., Ltd. | Polynucleotide for modifying target sequence and use thereof |
US20200353070A1 (en) | 2018-01-22 | 2020-11-12 | Japan As Represented By The Director-General Of National Institute Of Infectious Diseases | Selective cd8-positive t cell-inducing vaccine antigen |
CN112538498B (zh) * | 2020-04-20 | 2023-04-25 | 梅尔顿(深圳)生物医药技术有限公司 | 重组仙台病毒的构建方法及其应用 |
WO2022050419A1 (ja) | 2020-09-04 | 2022-03-10 | Heartseed株式会社 | iPS細胞の品質改善剤、iPS細胞の製造方法、iPS細胞、及びiPS細胞製造用組成物 |
AU2021409196A1 (en) | 2020-12-25 | 2023-08-03 | Id Pharma Co., Ltd. | Method for producing naive human ips cells from somatic cells |
WO2023227758A1 (en) | 2022-05-25 | 2023-11-30 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Vaccine with reduced anti-vector antigenicity |
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US6828138B1 (en) | 1998-08-11 | 2004-12-07 | Dnavec Research Inc. | Recombinant sendai virus vector including a gene encoding a chemokine |
DE69933528T2 (de) * | 1998-11-09 | 2007-08-09 | Nippon Biologicals, Inc. | Verfahren zur Cytokinproduktionn unter Verwendung eines Sendai Virus Expressionssystems |
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EP1270016A4 (de) | 2000-03-30 | 2005-10-19 | Dnavec Research Inc | Aidsvirus-impfstoff unter verwendung eines sendaivirus-vektors |
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CN1526014A (zh) | 2000-10-06 | 2004-09-01 | ��ʽ���������о��� | 用于将外源基因导入骨骼肌的副粘病毒载体 |
AU2002224113A1 (en) | 2000-11-27 | 2002-06-03 | Dnavec Research Inc. | Paramyxovirus vector encoding angiogenesis gene and utilization thereof |
JPWO2004038029A1 (ja) | 2002-10-24 | 2006-02-23 | 株式会社ディナベック研究所 | T細胞に遺伝子を導入する方法 |
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JPWO2005001082A1 (ja) | 2003-06-30 | 2006-08-10 | 株式会社ディナベック研究所 | 高変異領域が改変された遺伝子を搭載するマイナス鎖rnaウイルスベクター |
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CN1934260B (zh) | 2004-01-22 | 2013-03-13 | 株式会社载体研究所 | 利用含有巨细胞病毒增强子和鸡β-肌动蛋白启动子的杂合启动子制造负链RNA病毒载体的方法 |
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-
1996
- 1996-10-22 KR KR10-1998-0703241A patent/KR100525687B1/ko not_active IP Right Cessation
- 1996-10-22 DK DK96935403.4T patent/DK0863202T3/da active
- 1996-10-22 EP EP96935403A patent/EP0863202B1/de not_active Expired - Lifetime
- 1996-10-22 CN CNB961994762A patent/CN1143892C/zh not_active Expired - Lifetime
- 1996-10-22 WO PCT/JP1996/003069 patent/WO1997016539A1/ja active IP Right Grant
- 1996-10-22 CA CA2236378A patent/CA2236378C/en not_active Expired - Fee Related
- 1996-10-22 AU AU73352/96A patent/AU7335296A/en not_active Abandoned
- 1996-10-22 AT AT96935403T patent/ATE470704T1/de active
- 1996-10-22 DE DE69638196T patent/DE69638196D1/de not_active Expired - Lifetime
-
1999
- 1999-07-17 HK HK99103083A patent/HK1018078A1/xx not_active IP Right Cessation
-
2000
- 2000-12-01 US US09/728,207 patent/US7101685B2/en not_active Expired - Fee Related
-
2005
- 2005-05-17 US US11/130,117 patent/US7442544B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
KR100525687B1 (ko) | 2005-11-25 |
CN1207124A (zh) | 1999-02-03 |
EP0863202A4 (de) | 1999-03-03 |
KR19990067271A (ko) | 1999-08-16 |
DK0863202T3 (da) | 2010-09-27 |
US7442544B2 (en) | 2008-10-28 |
EP0863202B1 (de) | 2010-06-09 |
CA2236378C (en) | 2011-01-25 |
US20020098576A1 (en) | 2002-07-25 |
CA2236378A1 (en) | 1997-05-09 |
CN1143892C (zh) | 2004-03-31 |
EP0863202A1 (de) | 1998-09-09 |
AU7335296A (en) | 1997-05-22 |
US20050266566A1 (en) | 2005-12-01 |
WO1997016539A1 (fr) | 1997-05-09 |
ATE470704T1 (de) | 2010-06-15 |
HK1018078A1 (en) | 1999-12-10 |
US7101685B2 (en) | 2006-09-05 |
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