DK577783A - Vektor for udtrykkelse af et dna-segment i gaer - Google Patents

Vektor for udtrykkelse af et dna-segment i gaer Download PDF

Info

Publication number
DK577783A
DK577783A DK577783A DK577783A DK577783A DK 577783 A DK577783 A DK 577783A DK 577783 A DK577783 A DK 577783A DK 577783 A DK577783 A DK 577783A DK 577783 A DK577783 A DK 577783A
Authority
DK
Denmark
Prior art keywords
gaer
vector
expression
dna segment
dna
Prior art date
Application number
DK577783A
Other languages
English (en)
Other versions
DK173604B1 (da
DK577783D0 (da
Inventor
Rae Lyn Burke
Patricia Tekamp-Olson
Steven Rosenberg
Pablo D T Valenzuela
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23860419&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK577783(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of DK577783D0 publication Critical patent/DK577783D0/da
Publication of DK577783A publication Critical patent/DK577783A/da
Priority to DK199301074A priority Critical patent/DK173763B1/da
Application granted granted Critical
Publication of DK173604B1 publication Critical patent/DK173604B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Toys (AREA)
DK198305777A 1983-02-22 1983-12-15 Vektor for udtrykkelse i gær, bestående af et fremmed DNA-kodningssegment og en fremgangsmåde til udtrykkelse af DNA-kodningssegmentet i gær ved hjælp af en sådan vektor DK173604B1 (da)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK199301074A DK173763B1 (da) 1983-02-22 1993-09-23 Vektor for udtrykkelse i gær med en PyK promotor og en fremgangsmåde til syntese af hepatitis B virus overfladeantigen ved hjælp af en sådan vektor

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46858983A 1983-02-22 1983-02-22
US46858983 1983-02-22

Publications (3)

Publication Number Publication Date
DK577783D0 DK577783D0 (da) 1983-12-15
DK577783A true DK577783A (da) 1984-08-23
DK173604B1 DK173604B1 (da) 2001-04-23

Family

ID=23860419

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198305777A DK173604B1 (da) 1983-02-22 1983-12-15 Vektor for udtrykkelse i gær, bestående af et fremmed DNA-kodningssegment og en fremgangsmåde til udtrykkelse af DNA-kodningssegmentet i gær ved hjælp af en sådan vektor

Country Status (7)

Country Link
EP (4) EP0732403A1 (da)
JP (2) JPS59210888A (da)
AT (3) ATE55151T1 (da)
CA (2) CA1341302C (da)
DE (3) DE3486431T3 (da)
DK (1) DK173604B1 (da)
SG (1) SG48422A1 (da)

Families Citing this family (76)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU577259B2 (en) * 1982-08-13 1988-09-22 Zymogenetics Inc. Glycolytic promters for regulated protein expression protease inhibitor
JPS5931799A (ja) * 1982-08-16 1984-02-20 Science & Tech Agency Ｂ型肝炎ウイルス遺伝子を組込んだ組換えプラスミド
JPS5936699A (ja) * 1982-08-20 1984-02-28 Chemo Sero Therapeut Res Inst シヤトルベクタ−
US5422267A (en) * 1984-05-22 1995-06-06 Robert R. Yocum Industrial yeast comprising an integrated glucoamylase gene
EP0173997A1 (en) * 1984-09-06 1986-03-12 Chiron Corporation Feline leukemia virus protein vaccines and their preparation
EP0184575B1 (en) * 1984-12-06 1993-04-28 Fina Research S.A. Transformed yeasts producing lysozyme, plasmids used for this transformation, and uses thereof
DE3677851D1 (de) * 1985-08-05 1991-04-11 Merck & Co Inc Verfahren zur steigerung der produktion von rekombinantem protein in hefearten der gattung saccharomyces.
EP0218209B1 (en) * 1985-10-03 1992-02-05 Green Cross Corporation Yeast promoter and process for preparing heterologous protein
JPH0655155B2 (ja) * 1985-10-03 1994-07-27 株式会社ミドリ十字 蛋白質の製造方法
DK162900C (da) * 1985-10-24 1992-05-11 Danisco Fremgangsmaade til ekspression af gener i gaer samt dna-fragment, rekombineret dna-segment og plasmider, hvor disse indgaar til brug ved udoevelse af fremgangsmaaden
US4895800A (en) * 1985-11-26 1990-01-23 Phillips Petroleum Company Yeast production of hepatitis B surface antigen
JPS62236496A (ja) * 1986-04-07 1987-10-16 Green Cross Corp:The ＨＢｓＡｇの製造方法
US4839283A (en) * 1986-12-30 1989-06-13 Zymogenetics, Inc. Method of expressing alpha-1-antitrypsin in yeast
IL86832A (en) 1987-06-22 2002-09-12 Medeva Holdings Bv A recombinant DNA molecule containing a nucleotide sequence of part of the region encoding HBV pre-1s, an immunogenic particle containing multiple peptide monomers containing a pre-s1 epitope and pharmaceutical preparations containing it
CA1340772C (en) 1987-12-30 1999-09-28 Patricia Tekamp-Olson Expression and secretion of heterologous protiens in yeast employing truncated alpha-factor leader sequences
AU644619B2 (en) 1989-12-21 1993-12-16 Advanced Technologies (Cambridge) Limited Modification of plant metabolism
ZA909987B (en) * 1990-01-29 1991-09-25 Ciba Geigy Novel fungal expression system
US6194140B1 (en) 1990-04-04 2001-02-27 Chiron Corporation HCV NS3 protein fragments having helicase activity and improved solubility
EP0785273A1 (en) 1990-11-26 1997-07-23 Genetics Institute, Inc. Paired basic amino acid converting enzyme and DNA sequence encoding it
EP0491077A1 (en) * 1990-12-19 1992-06-24 Medeva Holdings B.V. A composition used as a therapeutic agent against chronic viral hepatic diseases
EP0697888B1 (en) 1993-05-12 2003-09-17 Chiron Corporation Conserved motif of hepatitis c virus e2/ns1 region
US5629167A (en) * 1994-04-19 1997-05-13 Biocine S.P.A. Detection of antibodies against Chlamydia trachomatis pgp3 antigen in patient sera by enzyme-linked immunosorbent assay
JPH08173170A (ja) * 1994-05-25 1996-07-09 Kirin Brewery Co Ltd キャンディダ・ユティリス酵母の形質転換系、およびそれによる異種遺伝子の発現
US5712249A (en) * 1994-09-08 1998-01-27 Ciba-Geigy Corporation Use of insulin-like growth factors I and II for inhibition of inflammatory response
AU725340B2 (en) 1995-12-22 2000-10-12 Gist-Brocades B.V. Improved methods for transforming Phaffia strains, transformed Phaffia strains so obtained and recombinant DNA in said methods
BR9813930A (pt) 1997-11-06 2006-12-19 Chiron Spa antìgeno neisserial
ATE446368T1 (de) 1998-01-14 2009-11-15 Novartis Vaccines & Diagnostic Antigene aus neisseria meningitidis
US6087128A (en) * 1998-02-12 2000-07-11 Ndsu Research Foundation DNA encoding an avian E. coli iss
GB9808932D0 (en) 1998-04-27 1998-06-24 Chiron Spa Polyepitope carrier protein
MX343752B (es) 1998-05-01 2016-11-22 Novartis Vaccines & Diagnostics Inc Antigenos de neisseria meningitidis y composiciones que los contienen.
NZ571167A (en) 1999-04-30 2010-05-28 Novartis Vaccines & Diagnostic Fragments from Neisseria protein ORF 953 and their use in medicaments and diagnostic reagents
GB9911683D0 (en) 1999-05-19 1999-07-21 Chiron Spa Antigenic peptides
GB9916529D0 (en) 1999-07-14 1999-09-15 Chiron Spa Antigenic peptides
PT2275551E (pt) 1999-10-29 2015-06-29 Novartis Vaccines & Diagnostic Péptidos antigénicos de neisseria
US6709863B2 (en) 1999-12-08 2004-03-23 Iowa State University Research Foundation Nucleic acid molecules encoding multiple start codons and histidine tags
ES2588917T3 (es) 2000-01-17 2016-11-07 Glaxosmithkline Biologicals Sa Vacuna de VME suplementada contra meningococo
US7939087B2 (en) 2000-10-27 2011-05-10 Novartis Vaccines And Diagnostics, Inc. Nucleic acids and proteins from Streptococcus groups A & B
US8008459B2 (en) 2001-01-25 2011-08-30 Evolva Sa Concatemers of differentially expressed multiple genes
WO2002059297A2 (en) 2001-01-25 2002-08-01 Evolva Biotech A/S A library of a collection of cells
GB0107661D0 (en) 2001-03-27 2001-05-16 Chiron Spa Staphylococcus aureus
GB0107658D0 (en) 2001-03-27 2001-05-16 Chiron Spa Streptococcus pneumoniae
ES2386386T3 (es) 2001-12-12 2012-08-20 Novartis Vaccines And Diagnostics S.R.L. Inmunización contra Chlamydia trachomatis
AU2003243316A1 (en) 2002-05-24 2003-12-12 Nps Allelix Corp. Method for enzymatic production of glp-2(1-33) and glp-2-(1-34) peptides
CA2506318C (en) 2002-11-15 2011-07-12 Chiron Srl Unexpected surface proteins in neisseria meningitidis
GB0308198D0 (en) 2003-04-09 2003-05-14 Chiron Srl ADP-ribosylating bacterial toxin
US7829307B2 (en) 2003-11-21 2010-11-09 Nps Pharmaceuticals, Inc. Production of glucagon-like peptide 2
DE10356218A1 (de) * 2003-12-03 2005-06-30 Bayer Cropscience Ag Verfahren zum Identifizieren von fungizid wirksamen Verbindungen basierend auf Pyruvatkinasen aus Pilzen
BRPI0507169A (pt) 2004-02-02 2007-06-26 Ambrx Inc polipeptìdeos do hormÈnio de crescimento humano modificados e seu usos
EP1771205B1 (en) 2004-06-18 2016-10-26 Ambrx, Inc. Novel antigen-binding polypeptides and their uses
JP2008507280A (ja) 2004-07-21 2008-03-13 アンブレツクス・インコーポレイテツド 非天然コードアミノ酸を用いた生合成ポリペプチド
CA2594557C (en) 2004-12-22 2016-04-26 Ambrx, Inc. Modified human growth hormone
NZ555308A (en) 2004-12-22 2010-10-29 Ambrx Inc Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides
JP4990792B2 (ja) 2004-12-22 2012-08-01 アンブレツクス・インコーポレイテツド アミノアシル−ｔＲＮＡシンテターゼの組成物およびこの使用
EP1871411A4 (en) 2005-04-18 2010-07-21 Novartis Vaccines & Diagnostic EXPRESSION OF HEPATITIS B VIRUS SURFACE ANTIGEN FOR VACCINE MANUFACTURE
WO2007021297A1 (en) 2005-08-18 2007-02-22 Ambrx, Inc. COMPOSITIONS OF tRNA AND USES THEREOF
CN102973929B (zh) 2005-09-01 2017-04-26 诺华疫苗和诊断有限两合公司 含血清群c脑膜炎球菌的多价疫苗
EP1951890A4 (en) 2005-11-16 2009-06-24 Ambrx Inc PROCESSES AND COMPOSITIONS WITH NON-NATURAL AMINO ACIDS
KR101423898B1 (ko) 2005-12-14 2014-07-28 암브룩스, 인코포레이티드 비-천연 아미노산 및 폴리펩티드를 함유하는 조성물, 비-천연 아미노산 및 폴리펩티드를 포함하는 방법, 및 비-천연 아미노산 및 폴리펩티드의 용도
DK2054431T3 (da) 2006-06-09 2012-01-02 Novartis Ag Konformere af bakterielle adhæsiner
KR20090060294A (ko) 2006-09-08 2009-06-11 암브룩스, 인코포레이티드 변형된 인간 혈장 폴리펩티드 또는 Ｆｃ 스캐폴드 및 그의 용도
AU2007292892B9 (en) 2006-09-08 2013-02-28 Ambrx, Inc. Hybrid suppressor tRNA for vertebrate cells
CA2682147C (en) 2007-03-30 2017-08-08 Ambrx, Inc. Modified fgf-21 polypeptides and their uses
WO2008139591A1 (ja) * 2007-05-11 2008-11-20 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute 組換えアプロチニンの生産方法
CA2703830A1 (en) 2007-11-20 2009-05-28 Ambrx, Inc. Modified insulin polypeptides and their uses
SG188143A1 (en) 2008-02-08 2013-03-28 Ambrx Inc Modified leptin polypeptides and their uses
EP2318029B1 (en) 2008-07-23 2017-11-01 Ambrx, Inc. Modified bovine g-csf polypeptides and their uses
US8278418B2 (en) 2008-09-26 2012-10-02 Ambrx, Inc. Modified animal erythropoietin polypeptides and their uses
PE20110480A1 (es) 2008-09-26 2011-07-01 Ambrx Inc Microorganismos y vacunas dependientes de replicacion de aminoacidos no naturales
EA201290541A1 (ru) 2009-12-21 2013-05-30 Амбркс, Инк. Модифицированные бычьи соматотропиновые полипептиды и их применение
JP2013515081A (ja) 2009-12-21 2013-05-02 アンブルックス，インコーポレイテッド 修飾されているブタのソマトトロピンポリペプチドおよびそれらの使用
WO2011146833A1 (en) 2010-05-20 2011-11-24 Evolva Inc. Method of producing isoprenoid compounds in yeast
PE20140160A1 (es) 2010-08-17 2014-02-08 Ambrx Inc Polipeptidos de relaxina modificados y sus usos
US9567386B2 (en) 2010-08-17 2017-02-14 Ambrx, Inc. Therapeutic uses of modified relaxin polypeptides
TWI480288B (zh) 2010-09-23 2015-04-11 Lilly Co Eli 牛顆粒細胞群落刺激因子及其變體之調配物
MX2017004947A (es) 2014-10-24 2017-06-29 Bristol Myers Squibb Co Polipeptidos del factor de crecimiento de fibroblastos 2 (fgf-21) modificados y usos de los mismos.
SG10201912034UA (en) 2017-02-08 2020-02-27 Bristol Myers Squibb Co Modified relaxin polypeptides comprising a pharmacokinetic enhancer and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ199722A (en) * 1981-02-25 1985-12-13 Genentech Inc Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain
GR76274B (da) * 1981-08-04 1984-08-04 Univ California
NZ201705A (en) * 1981-08-31 1986-03-14 Genentech Inc Recombinant dna method for production of hepatitis b surface antigen in yeast
JPS58146281A (ja) * 1981-10-19 1983-08-31 Suntory Ltd 酵母細胞の形質転換法
US4446235A (en) * 1982-03-22 1984-05-01 Genentech, Inc. Method for cloning human growth hormone varient genes
EP0096910B1 (en) * 1982-05-19 1989-04-19 Unilever N.V. Yeast of the genus kluyveromyces modified for the expression of preprothaumatin or its various allelic and modified forms or their maturation forms
AU577259B2 (en) * 1982-08-13 1988-09-22 Zymogenetics Inc. Glycolytic promters for regulated protein expression protease inhibitor
JPH0716432B2 (ja) * 1982-10-20 1995-03-01 サントリー株式会社 酵母の高発現ベクタープラスミドを用いたペプチドの生産方法

Also Published As

Publication number Publication date
JPH0515431B2 (da) 1993-03-01
ATE138975T1 (de) 1996-06-15
CA1341302C (en) 2001-10-09
DE3486431D1 (de) 1996-07-11
EP0120551B1 (en) 1990-08-01
ATE55151T1 (de) 1990-08-15
DE3482844D1 (de) 1990-09-06
EP0329203A1 (en) 1989-08-23
DE3486206D1 (de) 1993-10-07
ATE93894T1 (de) 1993-09-15
JPS59210888A (ja) 1984-11-29
DK173604B1 (da) 2001-04-23
DE3486431T3 (de) 2000-05-04
JPH0724594B2 (ja) 1995-03-22
EP0329203B1 (en) 1993-09-01
DK577783D0 (da) 1983-12-15
DE3486206T2 (de) 1994-02-03
JPH05268984A (ja) 1993-10-19
SG48422A1 (en) 1998-04-17
CA1341116C (en) 2000-10-17
DE3486431T2 (de) 1996-10-10
EP0120551A2 (en) 1984-10-03
EP0460716B1 (en) 1996-06-05
EP0120551A3 (en) 1986-05-14
EP0460716A1 (en) 1991-12-11
EP0460716B2 (en) 1999-12-15
EP0732403A1 (en) 1996-09-18

Similar Documents

Publication Publication Date Title
DK577783D0 (da) Vektor for udtrykkelse af et dna-segment i gaer
BG60107B2 (bg) Метод за получаване на еукариотен полипептид
EP1245678A3 (en) Recombinant proteins of viruses associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome
AU8223187A (en) T cell epitopes of the hepatitis b virus nucleocapsid protein
EG17949A (en) Yeast production of hepatitis b surface antigen
IE842210L (en) Vaccine
ATE35152T1 (de) Plasmide und modifizierte staemme von vibrio cholerae, ihre herstellung und davon abgeleitete vakzine.
EP0260148A3 (en) Improved recombinant expression method, vector and transformed cells
ATE451462T1 (de) Klonierung und expression von htlv-iii-dns
HK26684A (en) Purified proteins and process therefor
YU46723B (sh) Ekspresija, prerada i sekrecija heterologog proteina pomoću kvasca
DK0414475T3 (da) Fremgangsmåder til dyrkning af HCV i B- eller T-lymfocyt-cellelinier
ES8706208A1 (es) Un metodo para preparar proteinas que son inmunologicamente reactivas con anticuerpos para virus asociados con linfadenopatia
DE3381566D1 (de) Hepatitis-b-virus-gen enthaltendes rekombinantes plasmid, mit diesem rekombinanten plasmid transformierte hefe und herstellung von hepatitis-b-virus-oberflaechenantigen.
EP0152030A3 (en) Adult t cell leukemia virus antigen polypeptide
EP0228036A3 (en) Method for producing selected polypeptides in virally infected insect cells and polypeptides isolated therefrom
DK0396436T3 (da) Gærstammer til fremstilling af modne heterologe proteiner, især hirudin
AU2190288A (en) Vector for the expression of proteins of the HIV-2 virus, one of the casual agents of AIDS, cell culture infected or transformed by this vector, proteins obtained, vaccine and antibodies obtained
DK107493A (da) Vektor for udtrykkelse i gaer, bestaaende af et fremmed dna-segment og en fremgangsmaade til syntese af fremmede proteiner ved hjaelp af en saadan vektor
ES8800342A1 (es) Procedimiento para preparar un vector de levadura de copias multiples,estables y recombinante
DK204586A (da) Hybridceller, der producerer et karakteristisk antigen for hepatitis b-virus, opnaaet ud fra hepatocytter og celler, der er tilvejebragt fra aber, fremgangsmaade til opnaaelse af hybridcellerne og anvendelse af disse til produktion af antigenet
SU1380209A1 (ru) РЕКОМБИНАНТНАЯ ПЛАЗМИДНАЯ ДНК PUR 291-HAV 22, КОДИРУЮЩАЯ СИНТЕЗ ГИБРИДНОГО ПОЛИПЕПТИДА АНТИГЕННЫХ ДЕТЕРМИНАНТ ВИРУСА ГЕПАТИТА А С β -ГАЛАКТОЗИДАЗОЙ
AU2860384A (en) Cloning vector,method of constructing such,and method of concentrating and purifying product proteins produced by the cloning vector
DK28386A (da) Fremstilling af peptider
SE8204332D0 (sv) Cellodling, viruspropagering och interferonproduktion pa serumfritt medium

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired