ATA3589A - Neue isochinolinderivate, ihre herstellung und ihre verwendung - Google Patents

Neue isochinolinderivate, ihre herstellung und ihre verwendung

Info

Publication number
ATA3589A
ATA3589A AT35/89A AT3589A ATA3589A AT A3589 A ATA3589 A AT A3589A AT 35/89 A AT35/89 A AT 35/89A AT 3589 A AT3589 A AT 3589A AT A3589 A ATA3589 A AT A3589A
Authority
AT
Austria
Prior art keywords
isochinol
derivatives
new
production
new isochinol
Prior art date
Application number
AT35/89A
Other languages
English (en)
Other versions
AT394365B (de
Inventor
Klaus Hasspacher
Reto Naef
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of ATA3589A publication Critical patent/ATA3589A/de
Application granted granted Critical
Publication of AT394365B publication Critical patent/AT394365B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
AT0003589A 1988-01-08 1989-01-09 Neue isochinolinderivate, ihre herstellung und ihre verwendung AT394365B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888800397A GB8800397D0 (en) 1988-01-08 1988-01-08 Improvements in/relating to organic compounds

Publications (2)

Publication Number Publication Date
ATA3589A true ATA3589A (de) 1991-09-15
AT394365B AT394365B (de) 1992-03-25

Family

ID=10629678

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0003589A AT394365B (de) 1988-01-08 1989-01-09 Neue isochinolinderivate, ihre herstellung und ihre verwendung

Country Status (28)

Country Link
US (1) US4980359A (de)
JP (1) JPH0649686B2 (de)
KR (1) KR0142686B1 (de)
AT (1) AT394365B (de)
AU (1) AU622429B2 (de)
BE (1) BE1002730A3 (de)
CA (1) CA1332944C (de)
CH (1) CH678727A5 (de)
DE (1) DE3900233C2 (de)
DK (1) DK5789A (de)
ES (1) ES2010071A6 (de)
FI (1) FI90865C (de)
FR (1) FR2625743B1 (de)
GB (2) GB8800397D0 (de)
GR (1) GR1002750B (de)
HU (1) HU205083B (de)
IE (1) IE61914B1 (de)
IL (1) IL88899A (de)
IT (1) IT1229523B (de)
LU (1) LU87423A1 (de)
MY (1) MY103963A (de)
NL (1) NL8900029A (de)
NZ (1) NZ227561A (de)
PH (1) PH25640A (de)
PL (1) PL156099B1 (de)
PT (1) PT89405B (de)
SE (1) SE501548C2 (de)
ZA (1) ZA89133B (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2723674A (en) * 1951-11-28 1955-11-15 Charles E Harris Telephone cableman's tent
US3007541A (en) * 1959-02-24 1961-11-07 Jr John B Mast Temporary covering and support structure therefor
GB8807922D0 (en) * 1988-04-05 1988-05-05 Fujisawa Pharmaceutical Co Isoquinoline compound & process for preparation thereof
US4956371A (en) * 1989-09-19 1990-09-11 Euroceltique, S.A. Substituted isoquinolines and methods of using same
GB8921304D0 (en) * 1989-09-20 1989-11-08 Wyeth John & Brother Ltd New method of treatment and heterocyclic compounds used therein
GB9027055D0 (en) * 1990-12-13 1991-02-06 Sandoz Ltd Organic compounds
JPH06503564A (ja) * 1990-12-17 1994-04-21 シエル・インターナシヨネイル・リサーチ・マーチヤツピイ・ベー・ウイ 殺菌性イソキノリン誘導体
CA2093577C (en) * 1992-05-07 2006-01-03 Michael Klaus Alkyl or alkoxy substituted s-heterocyclic retinoids
US5350423A (en) * 1992-09-23 1994-09-27 Burlington Industries Inc. Fabric finishing procedure
GB9322828D0 (en) * 1993-11-05 1993-12-22 Sandoz Ltd Organic compounds
US5693323A (en) * 1994-12-23 1997-12-02 Smithkline Beecham Corporation Recombinant IL-5 antagonists useful in treatment of IL-5 mediated disorders
US7399837B2 (en) * 1995-12-22 2008-07-15 Smithkline Beecham Corporation Recombinant IL-5 antagonists useful in treatment of IL-5 mediated disorders
WO1996021000A2 (en) * 1994-12-23 1996-07-11 Smithkline Beecham Corporation Recombinant il-5 antagonists useful in treatment of il-5 mediated disorders
US5783184A (en) * 1994-12-23 1998-07-21 Smithkline Beecham Corporation Method for treatment and diagnosis of IL-5 mediated disorders
GB9622386D0 (en) * 1996-10-28 1997-01-08 Sandoz Ltd Organic compounds
IT1296985B1 (it) * 1997-12-19 1999-08-03 Zambon Spa Derivati benzazinici inibitori della fosfodiesterasi 4
ATE356810T1 (de) * 1999-01-15 2007-04-15 Altana Pharma Ag Polysubstituted 6-phenylphenanthridines mit pde- iv hemmender wirkung
SK287231B6 (sk) 1999-08-21 2010-04-07 Nycomed Gmbh Liečivo zahŕňajúce PDE inhibítor a agonistu beta2 adrenoreceptora
BRPI0409229A (pt) 2003-04-01 2006-03-28 Applied Research Systems inibidores das fosfodiesterases na infertilidade
WO2008134724A2 (en) * 2007-04-30 2008-11-06 Smithkline Beecham Corporation Methods for administering anti-il-5 antibodies
EP2274009B1 (de) 2008-03-28 2013-11-13 GlaxoSmithKline LLC Behandlungsverfahren
KR20110071014A (ko) 2008-10-17 2011-06-27 위스콘신 얼럼나이 리서어치 화운데이션 생물학적으로 활성인 알파-베타 펩티드의 제조 방법
CA3064859A1 (en) 2017-06-06 2018-12-13 Glaxosmithkline Llc Biopharmaceutical compositions and methods for pediatric patients

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB645139A (en) * 1946-10-22 1950-10-25 Servita Gyogyszeryar Es Vegyip Improved process for the production of isoquinoline derivatives
DE1184344B (de) * 1962-06-16 1964-12-31 Orgamol Sa Verfahren zur Herstellung von Isochinolinderivaten
US3878215A (en) * 1971-12-01 1975-04-15 Sandoz Ag 2-Alkyl-3-substituted-4-aryl isoquinolines
DE2401453A1 (de) * 1973-01-16 1974-07-18 John James Voorhees Pharmazeutische zusammensetzung zur behandlung von hautproliferationserkrankungen
US4018927A (en) * 1973-12-17 1977-04-19 The Regents Of The University Of Michigan Treatment of proliferating skin diseases with papaverine alkaloids
DE2503156A1 (de) * 1974-02-05 1975-08-07 Sandoz Ag Verfahren zur herstellung neuer heterocyclischer verbindungen
DE2811361A1 (de) * 1978-03-16 1979-09-27 Hoechst Ag Neue isochinolinaldehyde und verfahren zu ihrer herstellung
DE3244594A1 (de) * 1982-12-02 1984-06-07 Hoechst Ag, 6230 Frankfurt 1-phenylisochinolinderivate und verfahren zu ihrer herstellung, diese verbindung enthaltende pharmazeutische praeparate und deren anwendung
HU196758B (en) * 1986-05-21 1989-01-30 Gyogyszerkutato Intezet Process for production of 3-hidroxi-methil-quinolines and medical compositions containing them
PH25651A (en) * 1986-05-21 1991-08-21 Duphar Int Res New di, tetrahydroisoquinoline derivatives

Also Published As

Publication number Publication date
KR0142686B1 (ko) 1998-07-15
HUT52061A (en) 1990-06-28
US4980359A (en) 1990-12-25
PL277092A1 (en) 1989-09-04
IL88899A (en) 1994-07-31
AU622429B2 (en) 1992-04-09
KR890011851A (ko) 1989-08-22
MY103963A (en) 1993-10-30
DE3900233C2 (de) 2000-04-27
NZ227561A (en) 1991-11-26
FI890072A0 (fi) 1989-01-06
CA1332944C (en) 1994-11-08
NL8900029A (nl) 1989-08-01
DK5789A (da) 1989-07-09
GR890100008A (el) 1994-03-31
ZA89133B (en) 1990-09-26
HU205083B (en) 1992-03-30
SE8900039L (sv) 1989-07-09
PT89405A (pt) 1990-02-08
GB8900102D0 (en) 1989-03-01
SE8900039D0 (sv) 1989-01-05
BE1002730A3 (fr) 1991-05-21
GB2213482A (en) 1989-08-16
SE501548C2 (sv) 1995-03-13
AT394365B (de) 1992-03-25
AU2779589A (en) 1989-07-20
FR2625743A1 (fr) 1989-07-13
IE61914B1 (en) 1994-11-30
DE3900233A1 (de) 1989-07-20
GB2213482B (en) 1991-09-11
CH678727A5 (de) 1991-10-31
GR1002750B (el) 1997-08-26
IT1229523B (it) 1991-09-04
PH25640A (en) 1991-08-21
LU87423A1 (fr) 1989-08-30
PL156099B1 (pl) 1992-02-28
JPH0649686B2 (ja) 1994-06-29
PT89405B (pt) 1993-09-30
JPH01213267A (ja) 1989-08-28
FI90865B (fi) 1993-12-31
GB8800397D0 (en) 1988-02-10
IL88899A0 (en) 1989-08-15
IT8947504A0 (it) 1989-01-04
FI890072A (fi) 1989-07-09
FR2625743B1 (fr) 1990-11-09
DK5789D0 (da) 1989-01-06
ES2010071A6 (es) 1989-10-16
FI90865C (fi) 1994-04-11
IE890037L (en) 1989-07-08

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