ATA280489A - Neue adenosin-derivate, deren herstellung und verwendung - Google Patents

Neue adenosin-derivate, deren herstellung und verwendung

Info

Publication number
ATA280489A
ATA280489A AT0280489A AT280489A ATA280489A AT A280489 A ATA280489 A AT A280489A AT 0280489 A AT0280489 A AT 0280489A AT 280489 A AT280489 A AT 280489A AT A280489 A ATA280489 A AT A280489A
Authority
AT
Austria
Prior art keywords
production
adenosine derivatives
new adenosine
new
derivatives
Prior art date
Application number
AT0280489A
Other languages
English (en)
Other versions
AT397964B (de
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of ATA280489A publication Critical patent/ATA280489A/de
Application granted granted Critical
Publication of AT397964B publication Critical patent/AT397964B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/167—Purine radicals with ribosyl as the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biotechnology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AT0280489A 1988-12-13 1989-12-12 Neue adenosin-derivate, deren herstellung und verwendung AT397964B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3841881 1988-12-13

Publications (2)

Publication Number Publication Date
ATA280489A true ATA280489A (de) 1993-12-15
AT397964B AT397964B (de) 1994-08-25

Family

ID=6369027

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0280489A AT397964B (de) 1988-12-13 1989-12-12 Neue adenosin-derivate, deren herstellung und verwendung

Country Status (29)

Country Link
US (1) US5534503A (de)
JP (2) JPH0725786B2 (de)
KR (1) KR900009647A (de)
AT (1) AT397964B (de)
AU (1) AU618865B2 (de)
BE (1) BE1003632A3 (de)
CA (1) CA2005110A1 (de)
CH (1) CH678327A5 (de)
CS (1) CS411191A3 (de)
CY (1) CY1829A (de)
DE (1) DE3940021C2 (de)
DK (1) DK626989A (de)
ES (1) ES2022771A6 (de)
FR (1) FR2640271B1 (de)
GB (1) GB2226027B (de)
HK (1) HK70895A (de)
HU (1) HU211248A9 (de)
IE (1) IE65506B1 (de)
IL (1) IL92634A (de)
IT (1) IT1237431B (de)
LU (1) LU87639A1 (de)
MX (1) MX9203613A (de)
MY (1) MY106333A (de)
NL (1) NL8903054A (de)
NZ (1) NZ231701A (de)
PH (1) PH27533A (de)
SE (1) SE8904186L (de)
SG (1) SG8695G (de)
ZA (1) ZA899528B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0725785B2 (ja) * 1989-01-11 1995-03-22 日本臓器製薬株式会社 アデノシン誘導体及び該化合物を有効成分として含有する医薬組成物
DE4037363A1 (de) * 1990-04-09 1991-10-10 Europ Lab Molekularbiolog 2-0-alkylnukleotide sowie polymere, die solche nukleotide enthalten
US5561134A (en) * 1990-09-25 1996-10-01 Rhone-Poulenc Rorer Pharmaceuticals Inc. Compounds having antihypertensive, cardioprotective, anti-ischemic and antilipolytic properties
ES2095960T3 (es) * 1990-09-25 1997-03-01 Rhone Poulenc Rorer Int Compuestos que tienen propiedades antihipertensivas y antiisquemicas.
HUT61567A (en) 1990-12-07 1993-01-28 Sandoz Ag Process for producing new pharmaceutical compositions comprising 2'-o-alkyladenosine derivatives and for producing 6-cyclohexyl-2'-o-methyladenosinehydrate
GB9111580D0 (en) * 1991-05-30 1991-07-24 Wellcome Found Nucleoside derivative
US5705491A (en) * 1992-10-27 1998-01-06 Nippon Zoki Pharmaceutical Co., Ltd. Adenosine deaminase inhibitor
PL316985A1 (en) * 1994-05-10 1997-03-03 Sandoz Ltd Derivatives of adenosine
US6107300A (en) * 1996-03-27 2000-08-22 Dupont Pharmaceuticals Arylamino fused pyrimidines
JP3619017B2 (ja) 1998-06-24 2005-02-09 日本臓器製薬株式会社 新規アラビノシルアデニン誘導体

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL130136C (de) * 1966-10-20
DE2628202A1 (de) * 1976-06-23 1977-12-29 Max Planck Gesellschaft Verfahren zur herstellung von 2'-substituierten-d-ribofuranosylpurinderivaten
CA1239397A (en) * 1983-08-01 1988-07-19 James A. Bristol N.sup.6-substituted adenosines
DE3406533A1 (de) * 1984-02-23 1985-08-29 Boehringer Mannheim Gmbh, 6800 Mannheim Verwendung von adenosin-derivaten als antiallergica und arzneimittel, die diese enthalten
AU575438B2 (en) * 1984-10-26 1988-07-28 Warner-Lambert Company N6 - substituted deoxyribose analogues of adenosines
US4755594A (en) * 1986-01-31 1988-07-05 Warner-Lambert Company N6 -substituted adenosines
US4780452A (en) * 1986-09-08 1988-10-25 Burroughs Wellcome Co. F-substituted-3-β-D-ribofuranosyl-3H-imidazo[4,5-b]pyridines and pharmaceutical compositions thereof
WO1988003148A2 (en) * 1986-10-31 1988-05-05 Warner-Lambert Company Heteroaromatic derivatives of adenoside
US4843066A (en) * 1986-11-27 1989-06-27 Nippon Zoki Pharmaceutical Co., Ltd. Novel adenosine derivatives and pharmaceutical composition containing them as an active ingredient
US4962194A (en) * 1987-04-02 1990-10-09 Warner-Lambert Company Method of preparing 51,N6-disubstituted adenosines from inosines
GB8729994D0 (en) * 1987-12-23 1988-02-03 Glaxo Group Ltd Chemical compounds
JPH0725785B2 (ja) * 1989-01-11 1995-03-22 日本臓器製薬株式会社 アデノシン誘導体及び該化合物を有効成分として含有する医薬組成物

Also Published As

Publication number Publication date
JPH02218689A (ja) 1990-08-31
IL92634A0 (en) 1990-08-31
ZA899528B (en) 1991-08-28
CS411191A3 (en) 1992-06-17
AT397964B (de) 1994-08-25
DK626989D0 (da) 1989-12-12
JPH0725786B2 (ja) 1995-03-22
LU87639A1 (fr) 1991-09-18
NZ231701A (en) 1992-09-25
HK70895A (en) 1995-05-19
MY106333A (en) 1995-05-30
PH27533A (en) 1993-08-18
DK626989A (da) 1990-06-14
CY1829A (en) 1995-12-01
DE3940021C2 (de) 1994-08-25
FR2640271A1 (fr) 1990-06-15
IL92634A (en) 1994-01-25
MX9203613A (es) 1992-07-01
IE893965L (en) 1990-06-13
HU211248A9 (en) 1995-11-28
GB8925439D0 (en) 1989-12-28
SG8695G (en) 1995-06-16
CH678327A5 (de) 1991-08-30
NL8903054A (nl) 1990-07-02
IT1237431B (it) 1993-06-04
AU618865B2 (en) 1992-01-09
SE8904186D0 (sv) 1989-12-12
US5534503A (en) 1996-07-09
IT8948640A0 (it) 1989-12-12
DE3940021A1 (de) 1990-06-21
GB2226027B (en) 1992-05-20
JPH07223961A (ja) 1995-08-22
IT8948640A1 (it) 1991-06-12
BE1003632A3 (fr) 1992-05-12
KR900009647A (ko) 1990-07-05
CA2005110A1 (en) 1990-06-13
ES2022771A6 (es) 1991-12-01
FR2640271B1 (fr) 1995-02-03
GB2226027A (en) 1990-06-20
SE8904186L (sv) 1991-06-13
IE65506B1 (en) 1995-11-01
AU4617289A (en) 1990-06-21

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Legal Events

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