DE69206893D1 - Nucleosidderivate und deren Herstellung - Google Patents

Nucleosidderivate und deren Herstellung

Info

Publication number
DE69206893D1
DE69206893D1 DE69206893T DE69206893T DE69206893D1 DE 69206893 D1 DE69206893 D1 DE 69206893D1 DE 69206893 T DE69206893 T DE 69206893T DE 69206893 T DE69206893 T DE 69206893T DE 69206893 D1 DE69206893 D1 DE 69206893D1
Authority
DE
Germany
Prior art keywords
production
nucleoside derivatives
nucleoside
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69206893T
Other languages
English (en)
Other versions
DE69206893T2 (de
Inventor
Hiroshi Shiragami
Yumiko Uchida
Kunisuke Izawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Publication of DE69206893D1 publication Critical patent/DE69206893D1/de
Application granted granted Critical
Publication of DE69206893T2 publication Critical patent/DE69206893T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE69206893T 1991-06-19 1992-06-17 Nucleosidderivate und deren Herstellung Expired - Fee Related DE69206893T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3245290A JP3042073B2 (ja) 1991-06-19 1991-06-19 ヌクレオシド誘導体とその製造方法

Publications (2)

Publication Number Publication Date
DE69206893D1 true DE69206893D1 (de) 1996-02-01
DE69206893T2 DE69206893T2 (de) 1996-08-14

Family

ID=17131469

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69206893T Expired - Fee Related DE69206893T2 (de) 1991-06-19 1992-06-17 Nucleosidderivate und deren Herstellung

Country Status (4)

Country Link
US (1) US5625057A (de)
EP (1) EP0519464B1 (de)
JP (1) JP3042073B2 (de)
DE (1) DE69206893T2 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3677790B2 (ja) * 1993-08-04 2005-08-03 味の素株式会社 ヌクレオシド誘導体とその製造方法
US6391859B1 (en) 1995-01-27 2002-05-21 Emory University [5-Carboxamido or 5-fluoro]-[2′,3′-unsaturated or 3′-modified]-pyrimidine nucleosides
US5703058A (en) 1995-01-27 1997-12-30 Emory University Compositions containing 5-fluoro-2',3'-didehydro-2',3'-dideoxycytidine or a mono-, di-, or triphosphate thereof and a second antiviral agent
EP0827960A1 (de) 1996-09-10 1998-03-11 Ajinomoto Co., Inc. Verfahren zur Herstellung von Purinderivaten
US6090937A (en) * 1998-03-17 2000-07-18 Ajinomoto Co., Inc. Methods for producing nucleoside derivatives and intermediates therefor
US6579976B2 (en) * 1998-11-02 2003-06-17 Ajinomoto Co., Inc. Process for producing 2′,3′-diethyl substituted nucleoside derivatives
US7635690B2 (en) 1999-01-22 2009-12-22 Emory University HIV-1 mutations selected for by β-2′,3′-didehydro-2′,3′-dideoxy-5-fluorocytidine
US7115584B2 (en) 1999-01-22 2006-10-03 Emory University HIV-1 mutations selected for by β-2′,3′-didehydro-2′,3′-dideoxy-5-fluorocytidine
EP1363927A2 (de) * 2001-03-01 2003-11-26 Pharmasset Limited Verfahren zur herstellung von 2',3'-didehydronucleoside
US20050171126A1 (en) * 2003-12-26 2005-08-04 Ajinomoto Co., Inc. Process for the production of purine nucleoside compounds
WO2009125841A1 (ja) * 2008-04-10 2009-10-15 浜理薬品工業株式会社 ５－メチルウリジンを出発原料とするエチニルチミジン化合物の製造方法
CN103288907A (zh) * 2013-03-22 2013-09-11 西北师范大学 2’,3’-双脱氧尿苷的合成方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6038395A (ja) * 1983-08-10 1985-02-27 Daikin Ind Ltd ５−フルオロシチジン類の製法
JPH0692393B2 (ja) * 1987-04-17 1994-11-16 味の素株式会社 ジデヒドロヌクレオシド類の製造方法
US4835104A (en) * 1987-06-16 1989-05-30 Ajinomoto Co., Inc., Patent & Licensing Department Process for producing and purifying 2',3'-dideoxynucleosides, and process for producing 2',3'-dideoxy-2',3'-didehydronucleosides
US5290927A (en) * 1988-03-01 1994-03-01 Ajinomoto Co., Inc. Process for preparing 2',3'-dideoxyadenosine
US4904770A (en) * 1988-03-24 1990-02-27 Bristol-Myers Company Production of 2',3'-dideoxy-2',3'-didehydronucleosides
US5310895A (en) * 1989-12-21 1994-05-10 Ajinomoto Co., Inc. Method for production of nucleoside derivatives by selective hydrolysis
US5200514A (en) * 1990-01-19 1993-04-06 University Of Georgia Research Foundation, Inc. Synthesis of 2'-deoxypyrimidine nucleosides
JP3225545B2 (ja) * 1991-09-18 2001-11-05 味の素株式会社 非環状ヌクレオシド類の製造法

Also Published As

Publication number Publication date
EP0519464B1 (de) 1995-12-20
JP3042073B2 (ja) 2000-05-15
US5625057A (en) 1997-04-29
JPH051092A (ja) 1993-01-08
EP0519464A1 (de) 1992-12-23
DE69206893T2 (de) 1996-08-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee