DE69019550D1 - Piperidin-Derivate, ihre Herstellung und ihre Verwendung. - Google Patents
Piperidin-Derivate, ihre Herstellung und ihre Verwendung.Info
- Publication number
- DE69019550D1 DE69019550D1 DE69019550T DE69019550T DE69019550D1 DE 69019550 D1 DE69019550 D1 DE 69019550D1 DE 69019550 T DE69019550 T DE 69019550T DE 69019550 T DE69019550 T DE 69019550T DE 69019550 D1 DE69019550 D1 DE 69019550D1
- Authority
- DE
- Germany
- Prior art keywords
- preparation
- piperidine derivatives
- piperidine
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK82589A DK82589A (da) | 1989-02-22 | 1989-02-22 | Piperidinforbindelser, deres fremstilling og anvendelse |
DK231589A DK231589D0 (da) | 1989-05-12 | 1989-05-12 | Piperidinforbindelser og deres fremstilling og anvendelse |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69019550D1 true DE69019550D1 (de) | 1995-06-29 |
DE69019550T2 DE69019550T2 (de) | 1995-10-05 |
Family
ID=26064725
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69019550T Expired - Fee Related DE69019550T2 (de) | 1989-02-22 | 1990-02-14 | Piperidin-Derivate, ihre Herstellung und ihre Verwendung. |
Country Status (22)
Country | Link |
---|---|
US (5) | US5043345A (de) |
EP (2) | EP0384285A3 (de) |
JP (2) | JP2921578B2 (de) |
KR (1) | KR0163763B1 (de) |
CN (1) | CN1028105C (de) |
AR (1) | AR247565A1 (de) |
AT (1) | ATE123030T1 (de) |
AU (2) | AU629302B2 (de) |
CA (2) | CA2010579A1 (de) |
DE (1) | DE69019550T2 (de) |
DK (1) | DK0384288T3 (de) |
ES (1) | ES2072323T3 (de) |
FI (2) | FI900887A0 (de) |
GR (1) | GR3017062T3 (de) |
HU (2) | HU221623B1 (de) |
IE (1) | IE69672B1 (de) |
IL (2) | IL93352A (de) |
NO (2) | NO900831L (de) |
NZ (1) | NZ232615A (de) |
PH (1) | PH26465A (de) |
PT (2) | PT93242A (de) |
RU (1) | RU2042676C1 (de) |
Families Citing this family (89)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0372125A1 (de) * | 1988-11-08 | 1990-06-13 | Akzo N.V. | Oxazol und Thiazol-Derivate |
US5264444A (en) * | 1989-02-22 | 1993-11-23 | Novo Nordisk A/S | Piperidine compounds and use |
US5260311A (en) * | 1989-02-22 | 1993-11-09 | Novo Nordisk A/S | Piperidine compounds and their use |
US5328925A (en) * | 1989-02-22 | 1994-07-12 | Novo Nordisk A/S | Piperidine compounds and their use |
US5043345A (en) * | 1989-02-22 | 1991-08-27 | Novo Nordisk A/S | Piperidine compounds and their preparation and use |
EP0459568A3 (en) * | 1990-05-31 | 1992-09-30 | Merck Sharp & Dohme Ltd. | Substituted oxadiazoles and thiadiazoles for use in the treatment of glaucoma and novel compounds having such use |
US5418240A (en) * | 1990-08-21 | 1995-05-23 | Novo Nordisk A/S | Heterocyclic compounds and their preparation and use |
US5527813A (en) * | 1990-08-21 | 1996-06-18 | Novo Nordisk A/S | Heterocyclic compounds and their preparation and use |
DK198490D0 (da) * | 1990-08-21 | 1990-08-21 | Novo Nordisk As | Heterocykliske forbindelser, deres fremstilling og anvendelse |
DK198590D0 (da) * | 1990-08-21 | 1990-08-21 | Novo Nordisk As | Heterocykliske forbindelser, deres fremstilling og anvendelse |
USRE35822E (en) * | 1990-08-21 | 1998-06-09 | Novo Nordisk A/S | Heterocyclic compounds |
DK198390D0 (da) * | 1990-08-21 | 1990-08-21 | Novo Nordisk As | Heterocykliske forbindelser, deres fremstilling og anvendelse |
US5376668A (en) * | 1990-08-21 | 1994-12-27 | Novo Nordisk A/S | Heterocyclic compounds |
JPH06503563A (ja) * | 1990-11-29 | 1994-04-21 | アラーガン、インコーポレイテッド | 高眼圧の処置におけるピリジン誘導体の用途 |
EP0492903A1 (de) * | 1990-12-21 | 1992-07-01 | MERCK SHARP & DOHME LTD. | Substituierte Pyrazine, Pyrimidine und Pyridazine zur Anwendung in der Behandlung von Glaukoma |
IE922270A1 (en) * | 1991-07-26 | 1993-01-27 | Akzo Nv | Pyrazole derivatives |
US5641791A (en) * | 1991-08-13 | 1997-06-24 | Novo Nordisk A.S | Heterocyclic compounds and their preparation and use |
US5175166A (en) * | 1991-08-27 | 1992-12-29 | The University Of Toledo | Muscarinic agonists |
WO1993014089A1 (en) * | 1992-01-13 | 1993-07-22 | Novo Nordisk A/S | Heterocyclic compounds and their preparation and use |
US5244906A (en) * | 1992-01-23 | 1993-09-14 | Dowelanco | Insect control with substituted oxadiazole and thiadiazole compounds |
JPH08502508A (ja) * | 1992-10-23 | 1996-03-19 | メルク シヤープ エンド ドーム リミテツド | ドーパミンレセプターサブタイプリガンド |
KR100339115B1 (ko) * | 1993-06-04 | 2002-11-07 | 노보 노르디스크 에이/에스 | 결정성3-(4-헥실옥시-1,2,5-티아디아졸-3-일)-1,2,5,6-테트라하이드로-1-메틸피리딘(+)l-하이드로겐타르트레이트,이의제조방법및이를포함하는약제학적조성물 |
NZ271311A (en) * | 1993-08-19 | 1999-09-29 | Novo Nordisk As | Pharmaceutical usage of oxa- or thia-diazole-substituted pyridines |
US5753683A (en) * | 1993-08-19 | 1998-05-19 | Novo Nordisk A/S | Antipsychotic method |
US5545638A (en) * | 1993-12-21 | 1996-08-13 | Novo Nordisk A/S | Method of treating gastrointestinal motility disorders |
IL112024A (en) * | 1993-12-21 | 1999-07-14 | Novo Nordisk As | Pharmaceutical compositions comprising tetrahydropyridine derivatives substituted with oxadiazole or thiadiazole for treating gastrointestinal motility disorders |
US5929247A (en) * | 1994-10-24 | 1999-07-27 | Eli Lilly And Company | Heterocyclic compounds and their preparation and use |
US5605908A (en) * | 1994-10-24 | 1997-02-25 | Eli Lilly And Company | Heterocyclic compounds and their use |
US5998404A (en) * | 1994-10-24 | 1999-12-07 | Eli Lilly And Company | Heterocyclic compounds and their use |
US5726193A (en) * | 1994-10-31 | 1998-03-10 | Eli Lilly And Company | Method for treating anxiety |
US5484794A (en) * | 1994-11-09 | 1996-01-16 | Eli Lilly And Company | Method for treating anxiety |
US5574028A (en) * | 1994-10-31 | 1996-11-12 | Eli Lilly And Company | Method for treating anxiety |
US5488056A (en) * | 1994-10-31 | 1996-01-30 | Eli Lilly And Company | Method for treating anxiety |
CA2202776A1 (en) * | 1994-10-31 | 1996-05-09 | Franklin Porter Bymaster | Method for treating anxiety |
US5612351A (en) * | 1994-11-08 | 1997-03-18 | Novo Nordisk A/S | Method of treating urinary bladder dysfunctions |
US5565475A (en) * | 1994-11-08 | 1996-10-15 | Muhlhauser; Mark A. | Method of treating urinary bladder dysfunctions with 3-tetrahydropyridine derivatives |
TW304167B (de) * | 1995-01-30 | 1997-05-01 | Lilly Co Eli | |
US5605701A (en) * | 1995-02-17 | 1997-02-25 | Eli Lilly And Company | Transdermal formulation |
US5852037A (en) * | 1995-11-13 | 1998-12-22 | Eli Lilly And Company | Method for treating anxiety |
US5763457A (en) | 1995-11-13 | 1998-06-09 | Eli Lilly And Company | Method for treating anxiety |
US5998434A (en) * | 1995-12-06 | 1999-12-07 | Eli Lilly And Company | Composition for treating pain |
NZ324594A (en) * | 1995-12-07 | 1999-09-29 | Lilly Co Eli | A method and composition for treating pain using a composition comprising an azacyclic azabicyclic or tetrahydropyridine compound and an analgesic |
GB9603755D0 (en) * | 1996-02-22 | 1996-04-24 | Pfizer Ltd | Therapeutic agents |
JP2000509042A (ja) * | 1996-04-23 | 2000-07-18 | イーライ・リリー・アンド・カンパニー | ヘテロサイクリック化合物群 |
EP0912183A4 (de) * | 1996-04-23 | 1999-08-04 | Lilly Co Eli | Heterozyclische zusammensetzungen |
WO1997040045A1 (en) * | 1996-04-24 | 1997-10-30 | Novo Nordisk A/S | Heterocyclic compounds and their preparation and use |
US6090829A (en) * | 1996-08-01 | 2000-07-18 | Eli Lilly And Company | Method for treating excessive aggression |
US6043258A (en) * | 1996-08-01 | 2000-03-28 | Eli Lilly And Company | Method for treating disruptive behavior disorders with xanomeline |
EP0821959A3 (de) * | 1996-08-01 | 1998-09-16 | Eli Lilly And Company | Verwendung von 3-(4-Hexyloxy-1,2,5-Thiadiazol-3-yl)-1,2,5,6-Tetrahydro-1-Methylpyridin zur Behandlung von Nikotin-Entzug |
EP0821958A3 (de) * | 1996-08-01 | 1998-07-08 | Eli Lilly And Company | Verwendung von 3-(4-Hexyloxy-1,2,5-Thiadiazol-3-yl)-1,2,5,6-Tetrahydro-1-Methylpyridin (Xanomelin) zur Behandlung von übermässiger Streitsucht |
EP0821956A1 (de) * | 1996-08-01 | 1998-02-04 | Eli Lilly And Company | Verfahren zur Behandlung disruptiver Verhaltensstörungen |
PT821955E (pt) * | 1996-08-01 | 2002-07-31 | Lilly Co Eli | Uso de 3-(4-hexiloxi-1,2,5-tiadiazol-3-il)-1,2,5,6-tetrahidro-1-metilpiridina (xanomelina) para o tratamento da doenca bipolar |
US6117890A (en) * | 1996-08-01 | 2000-09-12 | Eli Lilly And Company | Method for treating bipolar disorder |
EP0821957A3 (de) * | 1996-08-01 | 1998-04-22 | Eli Lilly And Company | Verwendung von 3-(4-Hexyloxy-1,2,5-Thiadiazol-3-yl)-1,2,5,6-Tetrahydro-1-Methylpyridin (Xanomelin) zur Behandlung von Drogenmissbrauch |
EP0821954A1 (de) * | 1996-08-01 | 1998-02-04 | Eli Lilly And Company | Verfahren zur Behandlung von geistiger Zurückgebliebenheit |
EP0934040A1 (de) * | 1996-10-23 | 1999-08-11 | Eli Lilly And Company | Methode zur behandlung von im zusammenhang mit aids auftretende dementia |
US6297262B1 (en) | 1997-05-29 | 2001-10-02 | H. Lundbeck A/S | Treatment of schizophrenia and psychosis |
US6034108A (en) * | 1997-07-28 | 2000-03-07 | Eli Lilly And Company | Method for treating mental retardation |
US6528529B1 (en) | 1998-03-31 | 2003-03-04 | Acadia Pharmaceuticals Inc. | Compounds with activity on muscarinic receptors |
US6211204B1 (en) | 1999-01-22 | 2001-04-03 | University Of Toledo | Muscarinic receptor agonists |
US6376675B2 (en) * | 1999-01-22 | 2002-04-23 | The University Of Toledo | Muscarinic receptor agonists |
US6096767A (en) | 1999-01-22 | 2000-08-01 | The University Of Toledo | Muscarinic receptor agonists |
US20040023951A1 (en) * | 2001-06-18 | 2004-02-05 | Bymaster Franklin Porter | Combination therapy for treatment of psychoses |
EP2258358A3 (de) | 2005-08-26 | 2011-09-07 | Braincells, Inc. | Neurogenese mit Acetylcholinesterasehemmer |
US7678363B2 (en) * | 2005-08-26 | 2010-03-16 | Braincells Inc | Methods of treating psychiatric conditions comprising administration of muscarinic agents in combination with SSRIs |
CN1821243B (zh) * | 2005-08-30 | 2010-12-08 | 北京大学 | 取代的吡啶类m1受体激动剂、其制备方法及其用途 |
JP2009512711A (ja) | 2005-10-21 | 2009-03-26 | ブレインセルス,インコーポレイティド | Pde阻害による神経新生の調節 |
AU2006308889A1 (en) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | GABA receptor mediated modulation of neurogenesis |
CN101374836A (zh) * | 2005-12-27 | 2009-02-25 | 托莱多大学 | 毒蕈碱激动剂及其使用方法 |
US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
EP2377531A2 (de) | 2006-05-09 | 2011-10-19 | Braincells, Inc. | Neurogenese mittels Angiotensin-Modulation |
EP2026813A2 (de) | 2006-05-09 | 2009-02-25 | Braincells, Inc. | 5-ht-rezeptor-vermittelte neurogenese |
AU2007292848A1 (en) | 2006-09-08 | 2008-03-13 | Braincells, Inc. | Combinations containing a 4-acylaminopyridine derivative |
US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
US20110294835A1 (en) | 2008-05-15 | 2011-12-01 | The Board Of Trustees Of The University Of Illinois | Muscarinic Agonists as Cognitive Enhancers |
US20100216805A1 (en) | 2009-02-25 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
JP2012533621A (ja) | 2009-07-22 | 2012-12-27 | ピュアテック ベンチャーズ | ムスカリン性受容体活性化によって改善される疾患の治療のための方法および組成物 |
US10265311B2 (en) | 2009-07-22 | 2019-04-23 | PureTech Health LLC | Methods and compositions for treatment of disorders ameliorated by muscarinic receptor activation |
CA2818025A1 (en) | 2010-11-15 | 2012-05-24 | Agenebio, Inc. | Pyridazine derivatives, compositions and methods for treating cognitive impairment |
US9549928B2 (en) | 2011-04-29 | 2017-01-24 | The University Of Toledo | Muscarinic agonists as enhancers of cognitive flexibility |
US10329301B2 (en) | 2013-12-20 | 2019-06-25 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
MA42624A (fr) | 2015-06-19 | 2021-04-28 | Agenebio Inc | Dérivés de benzodiazépine, compositions et méthodes de traitement de la déficience cognitive |
CA2996717A1 (en) | 2015-09-11 | 2017-03-16 | Chase Pharmaceuticals Corporation | Muscarinic combination and its use for combating hypocholinergic disorders of the central nervous system |
US20180170941A1 (en) | 2016-12-19 | 2018-06-21 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
BR112019012821A2 (pt) | 2016-12-19 | 2019-11-26 | Agenebio Inc | derivados de benzodiazepina, composições e métodos para o tratamento do comprometimento cognitivo |
WO2019246300A1 (en) | 2018-06-19 | 2019-12-26 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
CN112789042A (zh) | 2018-09-28 | 2021-05-11 | 卡鲁娜治疗学有限公司 | 用于治疗由毒蕈碱受体激活所缓解的障碍的组合物和方法 |
WO2021097427A1 (en) | 2019-11-15 | 2021-05-20 | Karuna Therapeutics, Inc. | Xanomeline derivatives and methods for treating neurological disorders |
WO2024039886A1 (en) | 2022-08-19 | 2024-02-22 | Agenebio, Inc. | Benzazepine derivatives, compositions, and methods for treating cognitive impairment |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ219646A (en) * | 1986-03-27 | 1990-10-26 | Merck Sharp & Dohme | Oxadiazole derivatives of azacyclics for treating cns disorders |
IL83275A (en) * | 1986-09-08 | 1994-02-27 | Novo Nordisk As | Compounds 1,2, 4-Oxadiazolyl Pipridine Transformed, their preparation and pharmaceutical preparations containing them |
US5017618A (en) * | 1987-03-16 | 1991-05-21 | University Of Florida | Labile derivatives of ketone analogs of 3-substituted-1-alkylamino-2-propanols and their use as beta-adrenergic blockers |
GB8714789D0 (en) * | 1987-06-24 | 1987-07-29 | Lundbeck & Co As H | Heterocyclic compounds |
NZ225999A (en) * | 1987-09-10 | 1992-04-28 | Merck Sharp & Dohme | Azacyclic- or azabicyclic-substituted thiadiazole derivatives and pharmaceutical compositions |
IE63906B1 (en) * | 1987-11-13 | 1995-06-14 | Novo Nordisk As | Azabicyclic compounds and their preparation and use |
NZ227841A (en) * | 1988-02-12 | 1991-08-27 | Merck Sharp & Dohme | Heterocyclic compounds with at least two non-condensed five membered rings and pharmaceutical compositions |
DK162892C (da) * | 1988-07-04 | 1992-05-11 | Novo Nordisk As | 1,2,5,6-tetrahydropyridinforbindelser, deres fremstilling og farmaceutiske praeparater indeholdende disse |
US5328925A (en) * | 1989-02-22 | 1994-07-12 | Novo Nordisk A/S | Piperidine compounds and their use |
US5260311A (en) * | 1989-02-22 | 1993-11-09 | Novo Nordisk A/S | Piperidine compounds and their use |
US5043345A (en) * | 1989-02-22 | 1991-08-27 | Novo Nordisk A/S | Piperidine compounds and their preparation and use |
US5264444A (en) * | 1989-02-22 | 1993-11-23 | Novo Nordisk A/S | Piperidine compounds and use |
DK198490D0 (da) * | 1990-08-21 | 1990-08-21 | Novo Nordisk As | Heterocykliske forbindelser, deres fremstilling og anvendelse |
DK198390D0 (da) * | 1990-08-21 | 1990-08-21 | Novo Nordisk As | Heterocykliske forbindelser, deres fremstilling og anvendelse |
US5175166A (en) * | 1991-08-27 | 1992-12-29 | The University Of Toledo | Muscarinic agonists |
-
1989
- 1989-08-31 US US07/401,370 patent/US5043345A/en not_active Expired - Lifetime
-
1990
- 1990-02-12 IL IL9335290A patent/IL93352A/en not_active IP Right Cessation
- 1990-02-13 IE IE50490A patent/IE69672B1/en not_active IP Right Cessation
- 1990-02-14 PH PH40049A patent/PH26465A/en unknown
- 1990-02-14 DE DE69019550T patent/DE69019550T2/de not_active Expired - Fee Related
- 1990-02-14 DK DK90102913.2T patent/DK0384288T3/da active
- 1990-02-14 ES ES90102913T patent/ES2072323T3/es not_active Expired - Lifetime
- 1990-02-14 EP EP19900102889 patent/EP0384285A3/de not_active Withdrawn
- 1990-02-14 AT AT90102913T patent/ATE123030T1/de not_active IP Right Cessation
- 1990-02-14 EP EP90102913A patent/EP0384288B1/de not_active Expired - Lifetime
- 1990-02-16 IL IL93423A patent/IL93423A0/xx unknown
- 1990-02-20 AU AU49997/90A patent/AU629302B2/en not_active Ceased
- 1990-02-20 NZ NZ232615A patent/NZ232615A/en unknown
- 1990-02-20 AU AU49996/90A patent/AU4999690A/en not_active Abandoned
- 1990-02-20 US US07/482,272 patent/US5041455A/en not_active Expired - Lifetime
- 1990-02-21 CA CA002010579A patent/CA2010579A1/en not_active Abandoned
- 1990-02-21 CA CA002010578A patent/CA2010578C/en not_active Expired - Lifetime
- 1990-02-21 HU HU9000884A patent/HU221623B1/hu not_active IP Right Cessation
- 1990-02-21 AR AR90316209A patent/AR247565A1/es active
- 1990-02-21 RU SU904743296A patent/RU2042676C1/ru not_active IP Right Cessation
- 1990-02-21 KR KR1019900002108A patent/KR0163763B1/ko not_active IP Right Cessation
- 1990-02-21 NO NO90900831A patent/NO900831L/no unknown
- 1990-02-21 NO NO900830A patent/NO179639C/no not_active IP Right Cessation
- 1990-02-22 JP JP2039899A patent/JP2921578B2/ja not_active Expired - Fee Related
- 1990-02-22 FI FI900887A patent/FI900887A0/fi not_active Application Discontinuation
- 1990-02-22 PT PT93242A patent/PT93242A/pt not_active Application Discontinuation
- 1990-02-22 JP JP2039900A patent/JPH02255680A/ja active Pending
- 1990-02-22 FI FI900886A patent/FI95704C/fi active IP Right Grant
- 1990-02-22 PT PT93241A patent/PT93241B/pt not_active IP Right Cessation
- 1990-02-22 CN CN90100873A patent/CN1028105C/zh not_active Expired - Fee Related
-
1991
- 1991-08-15 US US07/745,568 patent/US5284859A/en not_active Expired - Lifetime
-
1995
- 1995-06-07 US US08/472,356 patent/US5559138A/en not_active Expired - Lifetime
- 1995-06-29 HU HU95P/P00607P patent/HU211705A9/hu unknown
- 1995-08-09 GR GR950402188T patent/GR3017062T3/el unknown
-
1996
- 1996-09-23 US US08/717,647 patent/US5712297A/en not_active Expired - Lifetime
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