ATE258549T1 - Oxazolidindion-derivate, ihre herstellung und verwendung - Google Patents
Oxazolidindion-derivate, ihre herstellung und verwendungInfo
- Publication number
- ATE258549T1 ATE258549T1 AT95307793T AT95307793T ATE258549T1 AT E258549 T1 ATE258549 T1 AT E258549T1 AT 95307793 T AT95307793 T AT 95307793T AT 95307793 T AT95307793 T AT 95307793T AT E258549 T1 ATE258549 T1 AT E258549T1
- Authority
- AT
- Austria
- Prior art keywords
- oxazolidindone
- derivatives
- preparation
- oxazolidindone derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/44—Two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/24—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP26982694 | 1994-11-02 | ||
JP17176895 | 1995-07-07 | ||
JP22094295 | 1995-08-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE258549T1 true ATE258549T1 (de) | 2004-02-15 |
Family
ID=27323527
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT95307793T ATE258549T1 (de) | 1994-11-02 | 1995-11-01 | Oxazolidindion-derivate, ihre herstellung und verwendung |
Country Status (14)
Country | Link |
---|---|
US (1) | US5932601A (de) |
EP (1) | EP0710659B1 (de) |
KR (1) | KR960017648A (de) |
AR (2) | AR002241A1 (de) |
AT (1) | ATE258549T1 (de) |
AU (1) | AU701847B2 (de) |
BR (1) | BR9505051A (de) |
CA (1) | CA2161944A1 (de) |
DE (1) | DE69532495T2 (de) |
FI (1) | FI955235A (de) |
HU (1) | HUT75101A (de) |
NO (1) | NO306401B1 (de) |
RU (1) | RU2144030C1 (de) |
TW (1) | TW403748B (de) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW438587B (en) | 1995-06-20 | 2001-06-07 | Takeda Chemical Industries Ltd | A pharmaceutical composition for prophylaxis and treatment of diabetes |
JPH09323930A (ja) * | 1996-04-04 | 1997-12-16 | Takeda Chem Ind Ltd | 悪液質の予防・治療剤 |
AU7595298A (en) * | 1997-12-02 | 1998-12-11 | Dr. Reddy's Research Foundation | Azolidinediones useful for the treatment of diabetes, dyslipidemia and hy pertension |
US6329372B1 (en) | 1998-01-27 | 2001-12-11 | Celltech Therapeutics Limited | Phenylalanine derivatives |
ES2226413T3 (es) | 1998-02-26 | 2005-03-16 | Celltech Therapeutics Limited | Derivados de fenilalanina como inhibidores de alfa-4 integrinas. |
GB9805655D0 (en) | 1998-03-16 | 1998-05-13 | Celltech Therapeutics Ltd | Chemical compounds |
US6521626B1 (en) | 1998-03-24 | 2003-02-18 | Celltech R&D Limited | Thiocarboxamide derivatives |
CA2291620C (en) | 1998-03-30 | 2003-10-07 | Japan Tobacco Inc. | Production method of isoxazolidinedione compound |
GB9811159D0 (en) | 1998-05-22 | 1998-07-22 | Celltech Therapeutics Ltd | Chemical compounds |
GB9811969D0 (en) | 1998-06-03 | 1998-07-29 | Celltech Therapeutics Ltd | Chemical compounds |
GB9812088D0 (en) | 1998-06-05 | 1998-08-05 | Celltech Therapeutics Ltd | Chemical compounds |
DE69919707T2 (de) * | 1998-06-19 | 2005-09-01 | Chiron Corp., Emeryville | Glycogen synthase kinase 3 inhibitoren |
GB9814414D0 (en) * | 1998-07-03 | 1998-09-02 | Celltech Therapeutics Ltd | Chemical compounds |
GB9821061D0 (en) | 1998-09-28 | 1998-11-18 | Celltech Therapeutics Ltd | Chemical compounds |
GB9821222D0 (en) | 1998-09-30 | 1998-11-25 | Celltech Therapeutics Ltd | Chemical compounds |
US6087385A (en) * | 1998-10-30 | 2000-07-11 | University Of Mississippi | Flavonoid derivatives |
GB9825652D0 (en) | 1998-11-23 | 1999-01-13 | Celltech Therapeutics Ltd | Chemical compounds |
GB9826174D0 (en) | 1998-11-30 | 1999-01-20 | Celltech Therapeutics Ltd | Chemical compounds |
NZ514662A (en) * | 1999-04-07 | 2004-01-30 | Sankyo Co | Amine derivatives |
TWI249401B (en) * | 1999-04-14 | 2006-02-21 | Takeda Chemical Industries Ltd | Agent for improving ketosis |
US6518283B1 (en) | 1999-05-28 | 2003-02-11 | Celltech R&D Limited | Squaric acid derivatives |
AU770870B2 (en) | 1999-06-18 | 2004-03-04 | Merck & Co., Inc. | Arylthiazolidinedione and aryloxazolidinedione derivatives |
AU773505B2 (en) | 1999-06-18 | 2004-05-27 | Merck & Co., Inc. | Arylthiazolidinedione and aryloxazolidinedione derivatives |
US6534513B1 (en) | 1999-09-29 | 2003-03-18 | Celltech R&D Limited | Phenylalkanoic acid derivatives |
US6455539B2 (en) | 1999-12-23 | 2002-09-24 | Celltech R&D Limited | Squaric acid derivates |
WO2001079173A2 (en) | 2000-04-17 | 2001-10-25 | Celltech R & D Limited | Enamine derivatives as cell adhesion molecules |
US6403608B1 (en) | 2000-05-30 | 2002-06-11 | Celltech R&D, Ltd. | 3-Substituted isoquinolin-1-yl derivatives |
US6545013B2 (en) | 2000-05-30 | 2003-04-08 | Celltech R&D Limited | 2,7-naphthyridine derivatives |
WO2002004426A1 (en) | 2000-07-07 | 2002-01-17 | Celltech R & D Limited | Squaric acid derivatives containing a bicyclic heteroaromatic ring as integrin antagonists |
EP1305291A1 (de) | 2000-08-02 | 2003-05-02 | Celltech R&D Limited | 3-substituierte isochinolin-1-yl-derivate |
AU9502601A (en) * | 2000-09-06 | 2002-03-22 | Chiron Corp | Inhibitors of glycogen synthase kinase 3 |
US7105551B2 (en) | 2000-12-20 | 2006-09-12 | Smithkline Beecham Corporation | Thiazole derivatives for treating PPAR related disorders |
EP1394154A4 (de) * | 2001-03-23 | 2005-05-18 | Takeda Pharmaceutical | Fünfgliedriges heterocyclisches alkansäurederivat |
WO2003059907A1 (fr) * | 2002-01-17 | 2003-07-24 | Takeda Chemical Industries, Ltd. | Composes heterocycliques azotes : procede de preparation et d'utilisation |
TWI327462B (en) * | 2002-01-18 | 2010-07-21 | Sumitomo Chemical Co | Condensed heterocyclic sulfonyl urea compound, a herbicide containing the same, and a method for weed control using the same |
US7232828B2 (en) * | 2002-08-10 | 2007-06-19 | Bethesda Pharmaceuticals, Inc. | PPAR Ligands that do not cause fluid retention, edema or congestive heart failure |
DE602004024382D1 (de) * | 2003-04-22 | 2010-01-14 | Wellstat Therapeutics Corp | Verbindungen zur behandlung von stoffwechselstörungen |
KR20080042188A (ko) | 2003-11-05 | 2008-05-14 | 에프. 호프만-라 로슈 아게 | Ppar 작용제로서 페닐 유도체 |
US7157584B2 (en) * | 2004-02-25 | 2007-01-02 | Takeda Pharmaceutical Company Limited | Benzimidazole derivative and use thereof |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4342771A (en) * | 1981-01-02 | 1982-08-03 | Pfizer Inc. | Hypoglycemic 5-substituted oxazolidine-2,4-diones |
US4332952A (en) * | 1980-07-28 | 1982-06-01 | Pfizer Inc. | Hypoglycemic 5-substituted oxazolidine-2,4-diones |
SG56656G (en) | 1980-07-28 | 1987-03-27 | Pfizer | Hypoglycemic 5-substituted oxazolidine-2, 4-diones |
US4430337A (en) | 1982-06-23 | 1984-02-07 | Pfizer Inc. | Alicyclic substituted oxazolidine-2,4-diones having hypoglycemic activity |
CN1003445B (zh) * | 1984-10-03 | 1989-03-01 | 武田药品工业株式会社 | 噻唑烷二酮衍生物,其制备方法和用途 |
WO1991007107A1 (en) * | 1989-11-13 | 1991-05-30 | Pfizer Inc. | Oxazolidinedione hypoglycemic agents |
GB9017218D0 (en) * | 1990-08-06 | 1990-09-19 | Beecham Group Plc | Novel compounds |
US5498621A (en) * | 1992-05-01 | 1996-03-12 | Pfizer Inc. | Oxazolidinedione hypoglycemic agents |
TW268952B (de) * | 1993-02-26 | 1996-01-21 | Takeda Pharm Industry Co Ltd | |
US5614544A (en) * | 1993-09-14 | 1997-03-25 | Takeda Chemical Industries, Ltd. | Oxazolidinedione derivatives and their use |
US5478852C1 (en) * | 1993-09-15 | 2001-03-13 | Sankyo Co | Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of impaired glucose tolerance in order to prevent or delay the onset of noninsulin-dependent diabetes mellitus |
CA2157032C (en) * | 1993-12-27 | 1999-09-28 | Hisashi Shinkai | Isoxazolidinedione derivative and use thereof |
CA2146701A1 (en) * | 1994-04-11 | 1995-10-12 | Takashi Fujita | Heterocyclic compounds having anti-diabetic activity, their preparation and their use |
US5468762A (en) * | 1994-05-18 | 1995-11-21 | American Home Products Corporation | Azolidinediones as antihyperglycemic agents |
-
1995
- 1995-10-28 TW TW084111412A patent/TW403748B/zh not_active IP Right Cessation
- 1995-10-30 US US08/550,289 patent/US5932601A/en not_active Expired - Lifetime
- 1995-10-31 KR KR1019950038881A patent/KR960017648A/ko not_active Application Discontinuation
- 1995-11-01 AU AU36607/95A patent/AU701847B2/en not_active Ceased
- 1995-11-01 NO NO954369A patent/NO306401B1/no not_active IP Right Cessation
- 1995-11-01 DE DE69532495T patent/DE69532495T2/de not_active Expired - Lifetime
- 1995-11-01 RU RU95118725A patent/RU2144030C1/ru active
- 1995-11-01 AT AT95307793T patent/ATE258549T1/de not_active IP Right Cessation
- 1995-11-01 FI FI955235A patent/FI955235A/fi unknown
- 1995-11-01 HU HU9503116A patent/HUT75101A/hu unknown
- 1995-11-01 BR BR9505051A patent/BR9505051A/pt not_active Application Discontinuation
- 1995-11-01 CA CA002161944A patent/CA2161944A1/en not_active Abandoned
- 1995-11-01 EP EP95307793A patent/EP0710659B1/de not_active Expired - Lifetime
- 1995-11-02 AR ARP950100022A patent/AR002241A1/es unknown
- 1995-11-02 AR ARP950100021A patent/AR002240A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
DE69532495D1 (de) | 2004-03-04 |
AR002241A1 (es) | 1998-03-11 |
NO954369L (no) | 1996-05-03 |
EP0710659B1 (de) | 2004-01-28 |
TW403748B (en) | 2000-09-01 |
AR002240A1 (es) | 1998-03-11 |
DE69532495T2 (de) | 2004-11-04 |
HU9503116D0 (en) | 1995-12-28 |
NO306401B1 (no) | 1999-11-01 |
US5932601A (en) | 1999-08-03 |
BR9505051A (pt) | 1997-10-21 |
FI955235A0 (fi) | 1995-11-01 |
RU2144030C1 (ru) | 2000-01-10 |
AU3660795A (en) | 1996-05-09 |
HUT75101A (en) | 1997-04-28 |
KR960017648A (ko) | 1996-06-17 |
AU701847B2 (en) | 1999-02-04 |
EP0710659A1 (de) | 1996-05-08 |
CA2161944A1 (en) | 1996-05-03 |
NO954369D0 (no) | 1995-11-01 |
FI955235A (fi) | 1996-05-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |