ATE202782T1 - Optisch-aktives benzothiepin-derivate, ihre herstellung und verwendung - Google Patents
Optisch-aktives benzothiepin-derivate, ihre herstellung und verwendungInfo
- Publication number
- ATE202782T1 ATE202782T1 AT95120444T AT95120444T ATE202782T1 AT E202782 T1 ATE202782 T1 AT E202782T1 AT 95120444 T AT95120444 T AT 95120444T AT 95120444 T AT95120444 T AT 95120444T AT E202782 T1 ATE202782 T1 AT E202782T1
- Authority
- AT
- Austria
- Prior art keywords
- preparation
- optically active
- active benzothiepine
- benzothiepine derivatives
- derivatives
- Prior art date
Links
- NIGNBCLEMMGDQP-UHFFFAOYSA-N 1-benzothiepine Chemical class S1C=CC=CC2=CC=CC=C12 NIGNBCLEMMGDQP-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms
- C07F9/655363—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a six-membered ring
- C07F9/655372—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/67—Phosphorus compounds having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
- C07F9/657163—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom
- C07F9/657181—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom the ring phosphorus atom and, at least, one ring oxygen atom being part of a (thio)phosphonic acid derivative
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP32727594 | 1994-12-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE202782T1 true ATE202782T1 (de) | 2001-07-15 |
Family
ID=18197308
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT95120444T ATE202782T1 (de) | 1994-12-28 | 1995-12-22 | Optisch-aktives benzothiepin-derivate, ihre herstellung und verwendung |
Country Status (20)
Country | Link |
---|---|
US (2) | US6346521B1 (de) |
EP (1) | EP0719782B1 (de) |
KR (1) | KR960022542A (de) |
CN (1) | CN1058718C (de) |
AR (1) | AR002018A1 (de) |
AT (1) | ATE202782T1 (de) |
AU (1) | AU689004B2 (de) |
BR (1) | BR9506098A (de) |
CA (1) | CA2166152A1 (de) |
DE (1) | DE69521595T2 (de) |
DK (1) | DK0719782T3 (de) |
ES (1) | ES2158034T3 (de) |
FI (1) | FI956273A (de) |
GR (1) | GR3036757T3 (de) |
HU (1) | HUT74562A (de) |
NO (1) | NO303641B1 (de) |
NZ (1) | NZ280745A (de) |
PT (1) | PT719782E (de) |
RU (1) | RU2162083C2 (de) |
TW (1) | TW403757B (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5910492A (en) * | 1995-06-05 | 1999-06-08 | Takeda Chemical Industries, Ltd. | Osteogenic promoting pharmaceutical composition |
HUP9802573A3 (en) * | 1995-06-05 | 2000-04-28 | Takeda Chemical Industries Ltd | Osteogenetic promoting pharmaceutical composition containing benzothian or benzothiepane derivatives and a biodegradable polimer |
KR19990029013A (ko) * | 1995-07-24 | 1999-04-15 | 다께다 구니오 | 광학 활성 벤조티에핀 염의 제조방법 |
EP0949927B1 (de) | 1996-08-26 | 2002-10-16 | Takeda Chemical Industries, Ltd. | Pharmazeutische zusammensetzung enthaltend ein osteogenese foerderndes mittel und ein polyethylen-glycol |
AU4571097A (en) * | 1996-10-09 | 1998-05-05 | Takeda Chemical Industries Ltd. | A method for producing a microparticle |
AU4165699A (en) * | 1998-06-15 | 2000-01-05 | Takeda Chemical Industries Ltd. | Composition for treating cartilage disease |
WO2000008018A1 (fr) | 1998-08-07 | 2000-02-17 | Takeda Chemical Industries, Ltd. | Derives de benzothiepine, leur procede de preparation et leurs utilisations |
WO2000009100A2 (en) * | 1998-08-12 | 2000-02-24 | Takeda Chemical Industries, Ltd. | Benzothiepine compounds as enhancer of cell differentiation induction factor |
EP1120122A1 (de) * | 1998-09-30 | 2001-08-01 | Takeda Chemical Industries, Ltd. | Knochenreparaturmaterial und zusammensetzungen für knochenersatz |
AU2001240115A1 (en) * | 2000-03-10 | 2001-09-24 | Pharmacia Corporation | Method for the preparation of tetrahydrobenzothiepines |
US20030158154A1 (en) * | 2001-07-17 | 2003-08-21 | Moshe Fleshner-Barak | Dosage forms for immediate gastric release of a calcium transport stimulator coupled with delayed gastric release of a bis-phosphonate |
US20050026871A1 (en) * | 2002-07-17 | 2005-02-03 | Moshe Flashner-Barak | Method of increasing bioavailability of alendronate or other bis-phosphonate by predose administration of vitamin D derivative |
US20060173009A1 (en) * | 2003-01-07 | 2006-08-03 | Hiroyuki Kanoh | Agent inducing increase in bone mass |
MX2009013767A (es) * | 2007-06-29 | 2010-01-26 | Kci Licensing Inc | Activacion de la formacion de hueso y cartilago. |
EP2380878B1 (de) | 2009-01-19 | 2013-08-14 | Daiichi Sankyo Company, Limited | Zyklische verbindung mit heteroatomen |
WO2010116915A1 (ja) | 2009-04-06 | 2010-10-14 | 第一三共株式会社 | 置換フェニル基を有する環状化合物 |
MX2012012145A (es) | 2010-04-28 | 2012-11-21 | Daiichi Sankyo Co Ltd | Compuestos [5, 6] heterociclico. |
CA2922716C (en) | 2013-08-29 | 2021-10-12 | Kyoto Pharmaceutical Industries, Ltd. | Aromatic compound and use thereof in the treatment of disorders associated with bone metabolism |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5158943A (en) * | 1988-11-21 | 1992-10-27 | Takeda Chemical Industries, Ltd. | Sulfur-containing heterocyclic compounds |
NZ231939A (en) | 1988-12-28 | 1991-07-26 | Takeda Chemical Industries Ltd | Benzothiopyran derivatives and medicaments |
ES2157887T3 (es) * | 1990-05-30 | 2001-09-01 | Takeda Chemical Industries Ltd | Compuestos heterociclicos que contienen azufre. |
JP3165866B2 (ja) * | 1990-06-06 | 2001-05-14 | 武田薬品工業株式会社 | 含硫黄複素環化合物 |
-
1995
- 1995-12-20 TW TW084113629A patent/TW403757B/zh not_active IP Right Cessation
- 1995-12-21 NZ NZ280745A patent/NZ280745A/en unknown
- 1995-12-22 PT PT95120444T patent/PT719782E/pt unknown
- 1995-12-22 AT AT95120444T patent/ATE202782T1/de not_active IP Right Cessation
- 1995-12-22 DK DK95120444T patent/DK0719782T3/da active
- 1995-12-22 DE DE69521595T patent/DE69521595T2/de not_active Expired - Fee Related
- 1995-12-22 ES ES95120444T patent/ES2158034T3/es not_active Expired - Lifetime
- 1995-12-22 AU AU40693/95A patent/AU689004B2/en not_active Ceased
- 1995-12-22 EP EP95120444A patent/EP0719782B1/de not_active Expired - Lifetime
- 1995-12-27 FI FI956273A patent/FI956273A/fi unknown
- 1995-12-27 NO NO955305A patent/NO303641B1/no not_active IP Right Cessation
- 1995-12-27 HU HU9503802A patent/HUT74562A/hu unknown
- 1995-12-27 BR BR9506098A patent/BR9506098A/pt unknown
- 1995-12-27 RU RU95122478/04A patent/RU2162083C2/ru active
- 1995-12-27 CA CA002166152A patent/CA2166152A1/en not_active Abandoned
- 1995-12-28 AR ARP950100805A patent/AR002018A1/es unknown
- 1995-12-28 CN CN95121715A patent/CN1058718C/zh not_active Expired - Fee Related
- 1995-12-28 KR KR1019950061545A patent/KR960022542A/ko not_active Application Discontinuation
- 1995-12-28 US US08/579,731 patent/US6346521B1/en not_active Expired - Fee Related
-
2000
- 2000-08-09 US US09/635,067 patent/US6632807B1/en not_active Expired - Fee Related
-
2001
- 2001-09-28 GR GR20010401614T patent/GR3036757T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0719782A1 (de) | 1996-07-03 |
HUT74562A (en) | 1997-01-28 |
DE69521595T2 (de) | 2002-05-23 |
ES2158034T3 (es) | 2001-09-01 |
NO955305D0 (no) | 1995-12-27 |
AR002018A1 (es) | 1998-01-07 |
FI956273A (fi) | 1996-06-29 |
US6346521B1 (en) | 2002-02-12 |
KR960022542A (ko) | 1996-07-18 |
NO955305L (no) | 1996-07-01 |
RU2162083C2 (ru) | 2001-01-20 |
HU9503802D0 (en) | 1996-02-28 |
EP0719782B1 (de) | 2001-07-04 |
US6632807B1 (en) | 2003-10-14 |
AU689004B2 (en) | 1998-03-19 |
NO303641B1 (no) | 1998-08-10 |
AU4069395A (en) | 1996-07-04 |
NZ280745A (en) | 1997-09-22 |
TW403757B (en) | 2000-09-01 |
DK0719782T3 (da) | 2001-09-24 |
DE69521595D1 (de) | 2001-08-09 |
CN1131669A (zh) | 1996-09-25 |
GR3036757T3 (en) | 2001-12-31 |
CN1058718C (zh) | 2000-11-22 |
PT719782E (pt) | 2001-10-31 |
BR9506098A (pt) | 1997-12-23 |
FI956273A0 (fi) | 1995-12-27 |
CA2166152A1 (en) | 1996-06-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |