GR3036757T3 - Optically active benzothiepin derivative, its preparation and use - Google Patents

Optically active benzothiepin derivative, its preparation and use

Info

Publication number
GR3036757T3
GR3036757T3 GR20010401614T GR20010401614T GR3036757T3 GR 3036757 T3 GR3036757 T3 GR 3036757T3 GR 20010401614 T GR20010401614 T GR 20010401614T GR 20010401614 T GR20010401614 T GR 20010401614T GR 3036757 T3 GR3036757 T3 GR 3036757T3
Authority
GR
Greece
Prior art keywords
preparation
optically active
benzothiepin derivative
active benzothiepin
derivative
Prior art date
Application number
GR20010401614T
Other languages
English (en)
Inventor
Takashi Sohda
Shigehisa Taketomi
Tsuneo Oda
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of GR3036757T3 publication Critical patent/GR3036757T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms
    • C07F9/655363—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a six-membered ring
    • C07F9/655372—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/67—Phosphorus compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
    • C07F9/657163—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom
    • C07F9/657181—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom the ring phosphorus atom and, at least, one ring oxygen atom being part of a (thio)phosphonic acid derivative
GR20010401614T 1994-12-28 2001-09-28 Optically active benzothiepin derivative, its preparation and use GR3036757T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP32727594 1994-12-28

Publications (1)

Publication Number Publication Date
GR3036757T3 true GR3036757T3 (en) 2001-12-31

Family

ID=18197308

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20010401614T GR3036757T3 (en) 1994-12-28 2001-09-28 Optically active benzothiepin derivative, its preparation and use

Country Status (20)

Country Link
US (2) US6346521B1 (el)
EP (1) EP0719782B1 (el)
KR (1) KR960022542A (el)
CN (1) CN1058718C (el)
AR (1) AR002018A1 (el)
AT (1) ATE202782T1 (el)
AU (1) AU689004B2 (el)
BR (1) BR9506098A (el)
CA (1) CA2166152A1 (el)
DE (1) DE69521595T2 (el)
DK (1) DK0719782T3 (el)
ES (1) ES2158034T3 (el)
FI (1) FI956273A (el)
GR (1) GR3036757T3 (el)
HU (1) HUT74562A (el)
NO (1) NO303641B1 (el)
NZ (1) NZ280745A (el)
PT (1) PT719782E (el)
RU (1) RU2162083C2 (el)
TW (1) TW403757B (el)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998008517A2 (en) 1996-08-26 1998-03-05 Takeda Chemical Industries, Ltd. Pharmaceutical composition containing osteogenesis-promoting substance and a polyethylene glycol
US5910492A (en) * 1995-06-05 1999-06-08 Takeda Chemical Industries, Ltd. Osteogenic promoting pharmaceutical composition
RU2188011C2 (ru) * 1995-06-05 2002-08-27 Такеда Кемикал Индастриз, Лтд. Активирующая остеогенез фармацевтическая композиция
US5952512A (en) * 1995-07-24 1999-09-14 Takeda Chemical Industries, Ltd. Production of optically active benzothiepin salts
EP0930874A2 (en) * 1996-10-09 1999-07-28 Takeda Chemical Industries, Ltd. A method for producing a microparticle
CA2334815A1 (en) * 1998-06-15 1999-12-23 Haruhiko Makino Composition for treating cartilage disease
US6355672B1 (en) 1998-08-07 2002-03-12 Takeda Chemical Industries, Ltd. Benzothiepin derivatives, process for the preparation of the same and uses thereof
CA2340165A1 (en) * 1998-08-12 2000-02-24 Haruhiko Makino Enhancer of cell differentiation induction factor
CN1321094A (zh) * 1998-09-30 2001-11-07 武田药品工业株式会社 骨修复材料和人造骨组合物
WO2001068637A2 (en) * 2000-03-10 2001-09-20 Pharmacia Corporation Method for the preparation of tetrahydrobenzothiepines
EP1416919A1 (en) * 2001-07-17 2004-05-12 Teva Pharmaceutical Industries Ltd. Dosage forms for immediate gastric release of a calcium transport stimulator coupled with delayed gastric release of a bis-phosphonate
US20050026871A1 (en) * 2002-07-17 2005-02-03 Moshe Flashner-Barak Method of increasing bioavailability of alendronate or other bis-phosphonate by predose administration of vitamin D derivative
JPWO2005002590A1 (ja) * 2003-07-01 2006-08-10 アステラス製薬株式会社 骨量増加誘導剤
EP2160169A4 (en) * 2007-06-29 2017-07-05 KCI Licensing, Inc. Activation of bone and cartilage formation
NZ593996A (en) 2009-01-19 2012-10-26 Daiichi Sankyo Co Ltd Naphthyridine-carboxamide and isoquinoline-carboxamide derivatives for treating osteoporosis
AU2010235619A1 (en) 2009-04-06 2011-11-10 Daiichi Sankyo Company, Limited Cyclic compound having substituted phenyl group
JPWO2011136264A1 (ja) 2010-04-28 2013-07-22 第一三共株式会社 ［５，６］複素環化合物
WO2015030189A1 (ja) 2013-08-29 2015-03-05 京都薬品工業株式会社 新規芳香族化合物およびその用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5158943A (en) * 1988-11-21 1992-10-27 Takeda Chemical Industries, Ltd. Sulfur-containing heterocyclic compounds
NZ231939A (en) * 1988-12-28 1991-07-26 Takeda Chemical Industries Ltd Benzothiopyran derivatives and medicaments
EP0460488B1 (en) * 1990-05-30 2001-07-11 Takeda Chemical Industries, Ltd. Sulfur-containing heterocyclic compounds
JP3165866B2 (ja) * 1990-06-06 2001-05-14 武田薬品工業株式会社 含硫黄複素環化合物

Also Published As

Publication number Publication date
CA2166152A1 (en) 1996-06-29
AR002018A1 (es) 1998-01-07
NO955305D0 (no) 1995-12-27
HUT74562A (en) 1997-01-28
FI956273A0 (fi) 1995-12-27
TW403757B (en) 2000-09-01
DE69521595D1 (de) 2001-08-09
NZ280745A (en) 1997-09-22
HU9503802D0 (en) 1996-02-28
ES2158034T3 (es) 2001-09-01
RU2162083C2 (ru) 2001-01-20
AU689004B2 (en) 1998-03-19
CN1058718C (zh) 2000-11-22
EP0719782B1 (en) 2001-07-04
US6632807B1 (en) 2003-10-14
DK0719782T3 (da) 2001-09-24
CN1131669A (zh) 1996-09-25
NO955305L (no) 1996-07-01
US6346521B1 (en) 2002-02-12
PT719782E (pt) 2001-10-31
NO303641B1 (no) 1998-08-10
ATE202782T1 (de) 2001-07-15
KR960022542A (ko) 1996-07-18
FI956273A (fi) 1996-06-29
DE69521595T2 (de) 2002-05-23
EP0719782A1 (en) 1996-07-03
AU4069395A (en) 1996-07-04
BR9506098A (pt) 1997-12-23

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Legal Events

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ML Lapse due to non-payment of fees