DK0719782T3 - Optisk aktive benzothiepinderivater samt fremstilling og anvendelse deraf - Google Patents
Optisk aktive benzothiepinderivater samt fremstilling og anvendelse derafInfo
- Publication number
- DK0719782T3 DK0719782T3 DK95120444T DK95120444T DK0719782T3 DK 0719782 T3 DK0719782 T3 DK 0719782T3 DK 95120444 T DK95120444 T DK 95120444T DK 95120444 T DK95120444 T DK 95120444T DK 0719782 T3 DK0719782 T3 DK 0719782T3
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- optically active
- active benzothiepine
- benzothiepine derivatives
- derivatives
- Prior art date
Links
- NIGNBCLEMMGDQP-UHFFFAOYSA-N 1-benzothiepine Chemical class S1C=CC=CC2=CC=CC=C12 NIGNBCLEMMGDQP-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms
- C07F9/655363—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a six-membered ring
- C07F9/655372—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/67—Phosphorus compounds having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
- C07F9/657163—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom
- C07F9/657181—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom the ring phosphorus atom and, at least, one ring oxygen atom being part of a (thio)phosphonic acid derivative
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP32727594 | 1994-12-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0719782T3 true DK0719782T3 (da) | 2001-09-24 |
Family
ID=18197308
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK95120444T DK0719782T3 (da) | 1994-12-28 | 1995-12-22 | Optisk aktive benzothiepinderivater samt fremstilling og anvendelse deraf |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US6346521B1 (de) |
| EP (1) | EP0719782B1 (de) |
| KR (1) | KR960022542A (de) |
| CN (1) | CN1058718C (de) |
| AR (1) | AR002018A1 (de) |
| AT (1) | ATE202782T1 (de) |
| AU (1) | AU689004B2 (de) |
| BR (1) | BR9506098A (de) |
| CA (1) | CA2166152A1 (de) |
| DE (1) | DE69521595T2 (de) |
| DK (1) | DK0719782T3 (de) |
| ES (1) | ES2158034T3 (de) |
| FI (1) | FI956273A (de) |
| GR (1) | GR3036757T3 (de) |
| HU (1) | HUT74562A (de) |
| NO (1) | NO303641B1 (de) |
| NZ (1) | NZ280745A (de) |
| PT (1) | PT719782E (de) |
| RU (1) | RU2162083C2 (de) |
| TW (1) | TW403757B (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998008517A2 (en) | 1996-08-26 | 1998-03-05 | Takeda Chemical Industries, Ltd. | Pharmaceutical composition containing osteogenesis-promoting substance and a polyethylene glycol |
| US5910492A (en) * | 1995-06-05 | 1999-06-08 | Takeda Chemical Industries, Ltd. | Osteogenic promoting pharmaceutical composition |
| RU2188011C2 (ru) * | 1995-06-05 | 2002-08-27 | Такеда Кемикал Индастриз, Лтд. | Активирующая остеогенез фармацевтическая композиция |
| US5952512A (en) * | 1995-07-24 | 1999-09-14 | Takeda Chemical Industries, Ltd. | Production of optically active benzothiepin salts |
| EP0930874A2 (de) * | 1996-10-09 | 1999-07-28 | Takeda Chemical Industries, Ltd. | Herstellungsverfahren für mikropartikel |
| CA2334815A1 (en) * | 1998-06-15 | 1999-12-23 | Haruhiko Makino | Composition for treating cartilage disease |
| US6355672B1 (en) | 1998-08-07 | 2002-03-12 | Takeda Chemical Industries, Ltd. | Benzothiepin derivatives, process for the preparation of the same and uses thereof |
| CA2340165A1 (en) * | 1998-08-12 | 2000-02-24 | Haruhiko Makino | Enhancer of cell differentiation induction factor |
| CN1321094A (zh) * | 1998-09-30 | 2001-11-07 | 武田药品工业株式会社 | 骨修复材料和人造骨组合物 |
| WO2001068637A2 (en) * | 2000-03-10 | 2001-09-20 | Pharmacia Corporation | Method for the preparation of tetrahydrobenzothiepines |
| EP1416919A1 (de) * | 2001-07-17 | 2004-05-12 | Teva Pharmaceutical Industries Ltd. | Dosierformen für die unmittelbare gastrische freisetzung eines calcium-transport-stimulators in verbindung mit der verzögerten gastrischen freisetzung eines bis-phosphonats |
| US20050026871A1 (en) * | 2002-07-17 | 2005-02-03 | Moshe Flashner-Barak | Method of increasing bioavailability of alendronate or other bis-phosphonate by predose administration of vitamin D derivative |
| JPWO2005002590A1 (ja) * | 2003-07-01 | 2006-08-10 | アステラス製薬株式会社 | 骨量増加誘導剤 |
| EP2160169A4 (de) * | 2007-06-29 | 2017-07-05 | KCI Licensing, Inc. | Aktivierung von knochen- und knorpelbildung |
| NZ593996A (en) | 2009-01-19 | 2012-10-26 | Daiichi Sankyo Co Ltd | Naphthyridine-carboxamide and isoquinoline-carboxamide derivatives for treating osteoporosis |
| AU2010235619A1 (en) | 2009-04-06 | 2011-11-10 | Daiichi Sankyo Company, Limited | Cyclic compound having substituted phenyl group |
| JPWO2011136264A1 (ja) | 2010-04-28 | 2013-07-22 | 第一三共株式会社 | ［５，６］複素環化合物 |
| WO2015030189A1 (ja) | 2013-08-29 | 2015-03-05 | 京都薬品工業株式会社 | 新規芳香族化合物およびその用途 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5158943A (en) * | 1988-11-21 | 1992-10-27 | Takeda Chemical Industries, Ltd. | Sulfur-containing heterocyclic compounds |
| NZ231939A (en) * | 1988-12-28 | 1991-07-26 | Takeda Chemical Industries Ltd | Benzothiopyran derivatives and medicaments |
| EP0460488B1 (de) * | 1990-05-30 | 2001-07-11 | Takeda Chemical Industries, Ltd. | Schwefel enthaltende heterocyclische Verbindungen |
| JP3165866B2 (ja) * | 1990-06-06 | 2001-05-14 | 武田薬品工業株式会社 | 含硫黄複素環化合物 |
-
1995
- 1995-12-20 TW TW084113629A patent/TW403757B/zh not_active IP Right Cessation
- 1995-12-21 NZ NZ280745A patent/NZ280745A/en unknown
- 1995-12-22 DK DK95120444T patent/DK0719782T3/da active
- 1995-12-22 ES ES95120444T patent/ES2158034T3/es not_active Expired - Lifetime
- 1995-12-22 AU AU40693/95A patent/AU689004B2/en not_active Ceased
- 1995-12-22 EP EP95120444A patent/EP0719782B1/de not_active Expired - Lifetime
- 1995-12-22 AT AT95120444T patent/ATE202782T1/de not_active IP Right Cessation
- 1995-12-22 PT PT95120444T patent/PT719782E/pt unknown
- 1995-12-22 DE DE69521595T patent/DE69521595T2/de not_active Expired - Fee Related
- 1995-12-27 RU RU95122478/04A patent/RU2162083C2/ru active
- 1995-12-27 NO NO955305A patent/NO303641B1/no not_active IP Right Cessation
- 1995-12-27 FI FI956273A patent/FI956273A/fi unknown
- 1995-12-27 BR BR9506098A patent/BR9506098A/pt unknown
- 1995-12-27 HU HU9503802A patent/HUT74562A/hu unknown
- 1995-12-27 CA CA002166152A patent/CA2166152A1/en not_active Abandoned
- 1995-12-28 CN CN95121715A patent/CN1058718C/zh not_active Expired - Fee Related
- 1995-12-28 KR KR1019950061545A patent/KR960022542A/ko not_active Application Discontinuation
- 1995-12-28 US US08/579,731 patent/US6346521B1/en not_active Expired - Fee Related
- 1995-12-28 AR ARP950100805A patent/AR002018A1/es unknown
-
2000
- 2000-08-09 US US09/635,067 patent/US6632807B1/en not_active Expired - Fee Related
-
2001
- 2001-09-28 GR GR20010401614T patent/GR3036757T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2166152A1 (en) | 1996-06-29 |
| AR002018A1 (es) | 1998-01-07 |
| NO955305D0 (no) | 1995-12-27 |
| HUT74562A (en) | 1997-01-28 |
| FI956273A0 (fi) | 1995-12-27 |
| TW403757B (en) | 2000-09-01 |
| DE69521595D1 (de) | 2001-08-09 |
| NZ280745A (en) | 1997-09-22 |
| HU9503802D0 (en) | 1996-02-28 |
| ES2158034T3 (es) | 2001-09-01 |
| RU2162083C2 (ru) | 2001-01-20 |
| AU689004B2 (en) | 1998-03-19 |
| CN1058718C (zh) | 2000-11-22 |
| EP0719782B1 (de) | 2001-07-04 |
| GR3036757T3 (en) | 2001-12-31 |
| US6632807B1 (en) | 2003-10-14 |
| CN1131669A (zh) | 1996-09-25 |
| NO955305L (no) | 1996-07-01 |
| US6346521B1 (en) | 2002-02-12 |
| PT719782E (pt) | 2001-10-31 |
| NO303641B1 (no) | 1998-08-10 |
| ATE202782T1 (de) | 2001-07-15 |
| KR960022542A (ko) | 1996-07-18 |
| FI956273A (fi) | 1996-06-29 |
| DE69521595T2 (de) | 2002-05-23 |
| EP0719782A1 (de) | 1996-07-03 |
| AU4069395A (en) | 1996-07-04 |
| BR9506098A (pt) | 1997-12-23 |
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